Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

EMBO Journal

Volumn 19, Issue 21, 2000, Pages 5752-5761

  Mas, Antonio ^a   Parera, Mariona ^b   Briones, Carlos ^c   Soriano, Vicente ^c   Martínez, Miguel Angel ^b   Domingo, Esteban ^a   Menéndez Arias, Luis ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

ATP dependent phosphorolysis; AZT resistance; HIV 1; Pyrophosphorolysis; Reverse transcriptase

Indexed keywords

AZATHIOPRINE; DIPEPTIDE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SERINE;

ARTICLE; CODON; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE INSERTION; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; VIRUS RECOMBINANT;

EID: 0034329473     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.21.5752     Document Type: Article

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