Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

Journal of Molecular Biology

Volumn 353, Issue 5, 2005, Pages 1021-1032

  Arias, Armando ^a   Agudo, Rubén ^a   Ferrer Orta, Cristina ^b   Pérez Luque, Rosa ^b   Airaksinen, Antero ^a   Brocchi, Emiliana ^c   Domingo, Esteban ^a   Verdaguer, Nuria ^b   Escarmís, Cristina ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

Author keywords

Foot and mouth disease virus; Lethal mutagenesis; Reversion; RNA dependent RNA polymerase; Viral quasispecies

Indexed keywords

AMINO ACID; MONOCLONAL ANTIBODY; MUTANT PROTEIN; RIBAVIRIN; VIRUS ENZYME;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONTROLLED STUDY; ESCHERICHIA COLI; FOOT AND MOUTH DISEASE VIRUS; GENETIC TRANSFECTION; MOLECULAR CLONING; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN MOTIF; RNA BINDING; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ESCHERICHIA COLI; FOOT-AND-MOUTH DISEASE VIRUS;

EID: 27144462037     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.09.022     Document Type: Article

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