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Volumn 277, Issue 8, 2002, Pages 5952-5961

Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors

(11) Gatanaga, Hiroyuki a,b,c Suzuki, Yasuhiro b Tsang, Hsinyi a Yoshimura, Kazuhisa b Kavlick, Mark F a Nagashima, Kunio c Gorelick, Robert J d Mardy, Sek a,b Tang, Chun a Summers, Michael F a Mitsuya, Hiroaki a,d

a NATIONAL INSTITUTES OF HEALTH (United States)

b KUMAMOTO UNIV SCHOOL OF MEDICINE (Japan)

c SAIC FREDERICK INC (United States)

d UNIVERSITY OF MARYLAND (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOASSAY; CHEMOTHERAPY; CLONING; MUTAGENESIS; VIRUSES;

CLEAVAGE SENSITIVITY;

PROTEINS;

AMPRENAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; GAG PROTEIN; JE 2147; KYNOSTATIN 272; PROTEINASE INHIBITOR; UIC 94003; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; VIRUS REPLICATION; VIRUS RESISTANCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-HIV AGENTS; CARBAMATES; CELL LINE; CLONING, MOLECULAR; DRUG RESISTANCE, MICROBIAL; GENE PRODUCTS, GAG; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; RESTRICTION MAPPING; SULFONAMIDES;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037155193 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M108005200 Document Type: Article

Times cited : (138)

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