Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)

Virology

Volumn 308, Issue 1, 2003, Pages 37-47

  Ruiz Jarabo, Carmen M ^a   Ly, Calvin ^b   Domingo, Esteban ^a   De La Torre, Juan Carlos ^b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; RIBAVIRIN; VIRUS RNA;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARENAVIRUS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; FOOT AND MOUTH DISEASE VIRUS; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MOUSE; MUTAGENESIS; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; RNA SYNTHESIS; VIRUS GENE; VIRUS GENOME; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ARENAVIRUS; CHORIOMENINGITIS VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; RNA VIRUSES;

EID: 0345578679     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(02)00046-6     Document Type: Article

References (59)

1. Alt F.W., Rathbun G., Oltz E., Taccioli G., Shinkai Y. Function and control of recombination-activating gene activity. Ann. NY Acad. Sci. 651:1992;277-294.
2. Bowen M.D., Peters C.J., Nichol S.T. Phylogenetic analysis of the Arenaviridae patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts . Mol. Phylogenet. Evol. 8:(3):1997;301-316.
3. Bowen M.D., Rollin P.E., Ksiazek T.G., Hustad H.L., Bausch D.G., Demby A.H., Bajani M.D., Peters C.J., Nichol S.T. Genetic diversity among Lassa virus strains. J. Virol. 74:(15):2000;6992-7004.
4. Buchmeier, M.J., Zajac, A.J. 1999. Lymphocitic choriomeningitis virus. In: Ahmed, R., Chen, J. (Eds.), Persistent Viral Infections, Vol. 1. John Wiley & Sons Ltd, pp. 575-605.
5. Campbell Dwyer E.J., Lai H., MacDonald R.C., Salvato M.S., Borden K.L. The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner. J. Virol. 74:(7):2000;3293-3300.
6. Cao W., Henry M.D., Borrow P., Yamada H., Elder J.H., Ravkov E.V., Nichol S.T., Compans R.W., Campbell K.P., Oldstone M.B. Identification of alpha- dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus [see comments]. Science. 282:(5396):1998;2079-2081.
7. Chao L. Fitness of RNA virus decreased by Muller's ratchet. Nature. 348:(6300):1990;454-455.
8. Cornu T.I., De Latorre J.C. RING finger Z protein of lymphocytic choriomeningitis virus (LCMV) inhibits transcription and RNA replication of an LCMV S- segment minigenome. J. Virol. 75:(19):2001;9415-9426.
9. Crotty S., Maag D., Arnold J.J., Zhong W., Lau J.Y.N., Hong Z., Andino R., Cameron C.E. The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen. Nature Medicine. 6:2000;1375-1379.
10. Crotty S., Cameron C.E., Aandino R. RNA virus error catastrophe direct molecular test by using ribavirin . Proc. Natl. Acad. Sci. USA. 98:(12):2001;6895-6900.
11. De la Torre J.C., Oldstone M.B. Selective disruption of growth hormone transcription machinery by viral infection. Proc. Natl. Acad. Sci. USA. 89:(20):1992;9939-9943.
12. Djavani M., Rodas J., Lukashevich I.S., Horejsh D., Pandolfi P.P., Borden K.L., Salvato M.S. Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virus. J. Virol. 75:(13):2001;6204-6208.
13. Domingo E., Holland J.J. RNA virus mutations and fitness for survival. Annu. Rev. Microbiol. 51:1997;151-178.
14. Domingo E., Biebricher C., Eigen M., Holland J.J. Quasispecies and RNA Virus EvolutionPrinciples and Consequences. 2001;Landes Bioscience, Austin.
15. Drake J.W., Holland J.J. Mutation rates among RNA viruses. Proc. Natl. Acad. Sci. USA. 96:1999;13910-13913.
16. Eigen M., Biebricher C.K. Sequence Space and Quasispecies Distribution. Domingo E., Ahlquist P., Holland J.J. RNA Genetics. Vol. 3:1988;211-245 CRC Press, Boca Raton, FL.
17. Eigen M. Natural selection a phase transition? Biophys. Chem. 85:(2-3):2000;101-123.
18. Fuller-Pace F.V., Southern P.J. Detection of virus-specific RNA-dependent RNA polymerase activity in extracts from cells infected with lymphocytic choriomeningitis virus In vitro synthesis of full-length viral RNA species . J. Virol. 63:(5):1989;1938-1944.
19. Ghosh A., Nayak R., Shaila M.S. Inhibition of replication of rinderpest virus by 5- fluorouracil. Antiviral Res. 31:(1-2):1996;35-44.
20. Holland J., Spindler K., Horodyski F., Grabau E., Nichol S., Vandepol S. Rapid evolution of RNA genomes. Science. 215:(4540):1982;1577-1585.
21. Holland J.J., Domingo E., De Latorre J.C., Steinhauer D.A. Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis. J. Virol. 64:1990;3960-3962.
22. Holland, J.J. (Ed.), 1992. Genetic Diversity of RNA Viruses, Curr. Top. Microbiol. Immunol., Vol. 176. Berlin: Springer-Verlag.
23. Huggins J.W., Robins R.K., Canonico P.G. Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. Antimicrob. Agents Chemother. 26:(4):1984;476-480.
24. Huggins J.W. Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad- spectrum antiviral drug. Rev. Infect. Dis. 11:(Suppl 4):1989;S750-S761.
25. Kentsis A., Dwyer E.C., Perez J.M., Sharma M., Chen A., Pan Z.Q., Borden K.L. The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E. J. Mol. Biol. 312:(4):2001;609-623.
26. Kunz S., Borrow P., Oldstone M.B.A. Receptor Structure, Binding and Cell Entry of Arenaviruses. Oldstone M.B.A. Arenaviruses I. Vol. 262:2002;111-138 Springer-Verlag, Berlin Heidelberg.
27. Lanford R.E., Chavez D., Guerra B., Lau J.Y., Hong Z., Brasky K.M., Beames B. Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. J. Virol. 75:(17):2001;8074-8081.
28. Lee K.J., Novella I.S., Teng M.N., Oldstone M.B., De Latorre J.C. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J. Virol. 74:(8):2000;3470-3477.
29. Loeb L.A., Essigmann J.M., Kazazi F., Zhang J., Rose K.D., Mullins J.I. Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Proc. Natl. Acad. Sci. USA. 96:1999;1492-1497.
30. Lucchinetti C.F., Kimmel D.W., Pavelko K., Rodriguez M. 5-Fluorouracil and levamisole exacerbate demyelination in susceptible mice infected with Theiler's virus. Exp. Neurol. 147:(1):1997;123-129.
31. McCormick J.B., Fisher-Hoch S.P. Lassa Fever. Oldstone M.B. Arenaviruses I. Vol. 262:2002;75-110 Springer-Verlag, Berlin, Heidelberg, New York.
32. McKee K.T. Jr., Huggins J.W., Trahan C.J., Mahlandt B.G. Ribavirin prophylaxis and therapy for experimental argentine hemorrhagic fever. Antimicrob. Agents Chemother. 32:(9):1988;1304-1309.
33. Meyer B.J., De Latorre J.C., Southern P.J. Arenaviruses Genomic RNAs, Transcription, and Replication . Oldstone M.B. Arenaviruses I. Vol. 262:2002;139-149 Springer-Verlag, Berlin Heidelberg.
34. Muller U., Steinhoff U., Reis L.F., Hemmi S., Pavlovic J., Zinkernagel R.M., Aguet M. Functional role of type I and type II interferons in antiviral defense. Science. 264:(5167):1994;1918-1921.
35. Najera I., Holguin A., Quinones-Mateu M.E., Munoz-Fernandez M.A., Najera R., Lopez-Galindez C., Domingo E. Pol gene quasispecies of human immunodeficiency virus mutations associated with drug resistance in virus from patients undergoing no drug therapy . J. Virol. 69:(1):1995;23-31.
36. Pariente, N., Sierra, S., Lowenstein, P.R., Domingo, E., 2001. Efficient viral extinction by combinations of a mutagen and antiviral inhibitors. Submitted for publication.
37. Parker W.B., Cheng Y.C. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol. Ther. 48:(3):1990;381-395.
38. Peters C.J. Human Infection with Arenaviruses in the Americas. Oldstone M.B. Arenaviruses I. Vol. 262:2002;65-74 Springer-Verlag, Berlin Heidelberg.
39. Peters C.J., Buchmeier, Michael, Rollin, Pierree, Ksiazek, Thomas G. Arenaviruses. Fields, Bernard N., Howely D.M.K., Peter M. Fields Virology. Vol. 2:1996;1521-1551 Lippincott-Raven Publishers, Philadelphia.
40. Pringle C.R. Genetic characteristics of conditional lethal mutants of vesicular stomatitis virus induced by 5-fluorouracil, 5-azacytidine, and ethyl methane sulfonate. J. Virol. 5:(5):1970;559-567.
41. Pringle C.R., Parry J.E. Measurement of surface antigen by specific bacterial adherence and scanning electron microscopy (SABA/SEM) in cells infected by vesiculovirus ts mutants. J. Gen. Virol. 59:(Pt 1):1982;207-211.
42. Salvato M., Shimomaye E., Oldstone M.B. The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase. Virology. 169:(2):1989;377-384.
43. Salvato M.S., Shimomaye E.M. The completed sequence of lymphocytic choriomeningitis virus reveals a unique RNA structure and a gene for a zinc finger protein. Virology. 173:(1):1989;1-10.
44. Salvato M.S., Schweighofer K.J., Burns J., Shimomaye E.M. Biochemical and immunological evidence that the 11 kDa zinc-binding protein of lymphocytic choriomeningitis virus is a structural component of the virus. Virus. Res. 22:(3):1992;185-198.
45. Salvato, M.S., 1993. Molecular biology of the prototype arenavirus lymphocytic choriomeningitis virus, in: Salvato, M.S. (Ed.) The Arenaviridae. F.-C. H. a. W. R.R. (Ed.), The Viruses. Plenum Press, New York, NY.
46. Sauder C., Muller A., Cubitt B., Mayer J., Steinmetz J., Trabert W., Ziegler B., Wanke K., Mueller-Lantzsch N., De Latorre J.C., Grasser F.A. Detection of Borna disease virus (BDV) antibodies and BDV RNA in psychiatric patients evidence for high sequence conservation of human blood-derived BDV RNA . J. Virol. 70:(11):1996;7713-7724.
47. Scheidel L.M., Durbin R.K., Stollar V. Sindbis virus mutants resistant to mycophenolic acid and ribavirin. Virology. 158:(1):1987;1-7.
48. Scheidel L.M., Stollar V. Mutations that confer resistance to mycophenolic acid and ribavirin on Sindbis virus map to the nonstructural protein nsP1. Virology. 181:(2):1991;490-499.
49. Schuster P., Stadler P.F. Nature and Evolution of Early Replicons. Domingo E., Webster R.G., Holland J.J. Origin and Evolution of Viruses. 1999;1-24 Academic Press, San Diego.
50. Sevilla N., Domingo E., De Latorre J.C. Contribution of LCMV towards deciphering biology of quasispecies in vivo. Curr. Top. Microbiol. Immunol. 263:2002;197-220.
51. Shinkai Y., Koyasu S., Nakayama K., Murphy K.M., Loh D.Y., Reinherz E.L., Alt F.W. Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science. 259:(5096):1993;822-825.
52. Sierra S., Dávila M., Lowenstein P.R., Domingo E. Response of foot-and-mouth disease virus to increased mutagenesis. Influence of viral load and fitness in loss of infectivity. J. Virol. 74:2000;8316-8323.
53. Snell N.J. Ribavirin-current status of a broad spectrum antiviral agent. Expert Opin. Pharmacother. 2:(8):2001;1317-1324.
54. Southern P.J. Arenaviridae The viruses and their replication . Bernard D.M.K., Fields N., Howley, Peter M. Fields Virology. Vol. 2:1996;1505-1551 Lippincott-Raven Publishers, Philadelphia.
55. Steinhauer D.A., Domingo E., Holland J.J. Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase. Gene. 122:(2):1992;281-288.
56. Swetina J., Schuster P. Self-replication with errors. A model for polynucleotide replication. Biophys. Chem. 16:(4):1982;329-345.
57. Teng M.N., Borrow P., Oldstone M.B., De Latorre J.C. A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome. J. Virol. 70:(12):1996;8438-8443.
58. Volkenstein M.V. Physical Approaches to Biological Evolution. 1994;Springer-Verlag, Berlin.
59. Yu H., Eritja R., Bloom L.B., Goodman M.F. Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine. J. Biol. Chem. 268:(21):1993;15935-15943.