Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: Diversification by mutation clustering

Journal of Molecular Biology

Volumn 315, Issue 4, 2002, Pages 647-661

  Escarmís, Cristina ^a   Gómez Mariano, Gema ^a   Dávila, Mercedes ^a   Lázaro, Ester ^b   Domingo, Esteban ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b CENTRO DE ASTROBIOLOGÍA CSIC INTA   (Spain)

Author keywords

Foot and mouth disease virus; Muller's ratchet; Mutation; Viral quasispecies

Indexed keywords

POLYADENYLIC ACID;

ANIMAL CELL; ARTICLE; CLONING; CONTROLLED STUDY; FOOT AND MOUTH DISEASE VIRUS; GENETIC VARIABILITY; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SPECIES EXTINCTION; VIRUS CULTURE; VIRUS RESISTANCE;

FOOT-AND-MOUTH DISEASE VIRUS; RNA VIRUSES;

EID: 0036301071     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5259     Document Type: Article

References (89)

1. The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate
2. Mutation rates among RNA viruses
3. Self-organization of matter and the evolution of biological macromolecules
4. On the nature of virus quasispecies
5. Rapid evolution of RNA genomes
6. RNA virus populations as quasispecies
7. The high rate of retrovirus variation results in rapid evolution
8. Nucleotide sequence heterogeneity of an RNA phage population
9. Evolutio-narily related Sindbis-like plant viruses maintain different levels of population diversity in a common host
10. Genetic diversity in RNA virus quasispecies is controlled by host-virus interactions
11. Molecular intermediates of fitness gain of an RNA virus: Characterization of a mutant spectrum by biological and molecular cloning
12. Interferon resistance of hepatitis C virus genotype 1b: Relationship to nonstructural 5A gene quasispecies mutations
13. Analysis of pol gene heterogeneity, viral quasispecies, and drug resistance in individuals infected with group O strains of human immunodeficiency virus type 1
14. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
15. Quasispecies in viral persistence and pathogenesis of hepatitis C virus
16. Hepatitis C virus resistance to antiviral therapy
17. Evolution of cell recognition by viruses
18. Self-replication with errors. A model for polynucleotide replication
19. Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet
20. Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis
21. 5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate
22. Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virus
23. Lethal mutagenesis of HIV with mutagenic nucleoside analogs
24. Response of foot-and-mouth disease virus to increased mutagenesis. Influence of viral load and fitness in loss of infectivity
25. The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen
26. Nature and evolution of early replicons
27. Viruses at the edge of adaptation
28. Fitness of RNA virus decreased by Muller's ratchet
29. Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet
30. Evolution of fitness in experimental populations of vesicular stomatitis virus
31. Genetic lesions associated with Muller's ratchet in an RNA virus
32. Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet
33. Drastic fitness loss in human immunodeficiency virus type 1 upon serial bottleneck events
34. Unusual distribution of mutations associated with serial bottleneck passages of human immunodeficiency virus type 1
35. Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses
36. The relation of recombination to mutational advance
37. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family; aspects of virus protein synthesis, protein processing and structure
38. Picornaviridae: The viruses and their replication
39. Foot-and-mouth disease virus: A long known virus, but a current threat
40. Efficient virus extinction by combinations of a mutagen and antiviral inhibitors
41. Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding
42. Frameshift mutation: Determinants of specificity
43. Mutagenicity and pausing of HIV reverse transcriptase during HIV plus- strand DNA synthesis
44. Prediction of RNA secondary structure by energy minimization
45. Modifications of the 5′ untranslated region of foot-and-mouth disease virus after prolonged persistence in cell culture
46. Large deletions in the 5′-untranslated region of foot-and-mouth disease virus of serotype C
47. Functional interactions in internal translation initiation directed by viral and cellular IRES elements
48. A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase
49. Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites
50. Genetic variability and antigenic diversity of foot-and-mouth disease virus
51. Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication
52. Emergence in Asia of foot-and-mouth disease viruses with attered host range: Characterization of alterations in the 3A protein
53. Heterogeneity of the genome-linked protein of foot-and-mouth disease virus
54. A tandem repeat gene in a picornavirus
55. Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg
56. VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus
57. Structure of the RNA-dependent RNA polymerase of poliovirus
58. Evolution of RNA viruses
59. Antibodies raised in a natural host and monoclonal antibodies recognize similar antigenic features of foot-and-mouth disease virus
60. Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host
61. Multiple virulence determinants of foot-and-mouth disease virus in cell culture
62. Evolution subverting essentiality: Dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus
63. Contingent neutrality in competing viral populations
64. Template-determined, variable rate of RNA chain elongation
65. Secondary structure formation during RNA synthesis
66. Comparison of pausing during transcription and replication
67. Direct measurement of the poliovirus RNA polymerase error frequency in vitro
68. Sequence variation in the gene for the immunogenic capsid protein VP1 of foot-and-mouth disease virus type A
69. Altering the intracellular environment increases the frequency of tandem repeat deletion during Moloney murine leukemia virus reverse transcription
70. Retroviral recombination is temperature dependent
71. Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors
72. Reverse transcription and the generation of retroviral DNA
73. Recombination in RNA
74. The mechanism of RNA recombination in poliovirus
75. RNA virus error catastrophe: Direct molecular test by using ribavirin
76. Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus
77. Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture
78. Quantitation of mRNA by the polymerase chain reaction
79. Genomic nucleotide sequence of a foot-and-mouth disease virus clone and its persistent derivatives. Implications for the evolution of viral quasispecies during a persistent infection
80. Aligning amino acid sequences: Comparison of commonly used methods