Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses

Nature Genetics

Volumn 37, Issue 7, 2005, Pages 701-709

  Crowder, Scott ^a   Kirkegaard, Karla ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN VIRAL PROTEINASE 2A; PROTEINASE; RNA POLYMERASE; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; CAPSID PROTEIN; CYSTEINE PROTEINASE; DISOXARIL; ISOXAZOLE DERIVATIVE; PICORNAIN 2A, PICORNAVIRUS; VIRUS PROTEIN;

ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE MUTATION; GENOME ANALYSIS; NONHUMAN; PHENOTYPE; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SYNTHESIS; RNA VIRUS; VIROGENESIS; VIRUS CAPSID; VIRUS GENOME; VIRUS INHIBITION; VIRUS REPLICATION; ALLELE; CHEMICAL STRUCTURE; DRUG EFFECT; GENETICS; HELA CELL; HUMAN; MUTATION; PHYSIOLOGY; PROTEIN SYNTHESIS;

MIRIDAE; POLIOVIRUS; RNA VIRUSES;

ALLELES; ANTIVIRAL AGENTS; CAPSID PROTEINS; CYSTEINE ENDOPEPTIDASES; DRUG RESISTANCE, VIRAL; GENOME, VIRAL; HELA CELLS; HUMANS; ISOXAZOLES; MODELS, MOLECULAR; MUTATION; PHENOTYPE; POLIOVIRUS; PROTEIN BIOSYNTHESIS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 22844440540     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1583     Document Type: Article

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