-
1
-
-
0002296754
-
Reverse transcriptase and the generation of retroviral DNA
-
Coffin J., Hughes S.H., and Varmus H.E. (Eds), Cold Spring Harbor Laboratory Press, Plainview, NY
-
Telesnitsky A., and Goff S.P. Reverse transcriptase and the generation of retroviral DNA. In: Coffin J., Hughes S.H., and Varmus H.E. (Eds). Retroviruses (1997), Cold Spring Harbor Laboratory Press, Plainview, NY 121-160
-
(1997)
Retroviruses
, pp. 121-160
-
-
Telesnitsky, A.1
Goff, S.P.2
-
2
-
-
33645891478
-
HIV-1 reverse transcriptase: a therapeutical target in the spotlight
-
Castro H.C., Loureiro N.I.V., Pujol-Luz M., Souza A.M.T., Albuquerque M.G., Santos D.O., et al. HIV-1 reverse transcriptase: a therapeutical target in the spotlight. Curr. Med. Chem. 13 (2006) 313-324
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 313-324
-
-
Castro, H.C.1
Loureiro, N.I.V.2
Pujol-Luz, M.3
Souza, A.M.T.4
Albuquerque, M.G.5
Santos, D.O.6
-
3
-
-
0036696712
-
Targeting HIV: antiretroviral therapy and development of drug resistance
-
Menéndez-Arias L. Targeting HIV: antiretroviral therapy and development of drug resistance. Trends Pharmacol. Sci. 23 (2002) 381-388
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 381-388
-
-
Menéndez-Arias, L.1
-
4
-
-
4444256678
-
Antivirals and antiviral strategies
-
De Clercq E. Antivirals and antiviral strategies. Nature Rev. Microbiol. 2 (2004) 704-720
-
(2004)
Nature Rev. Microbiol.
, vol.2
, pp. 704-720
-
-
De Clercq, E.1
-
5
-
-
19444384266
-
Molecular mechanisms of resistance to nucleoside analogue inhibitors of human immunodeficiency virus reverse transcriptase
-
Menéndez-Arias L., Matamoros T., Deval J., and Canard B. Molecular mechanisms of resistance to nucleoside analogue inhibitors of human immunodeficiency virus reverse transcriptase. Drug Design Rev. (On line) 2 (2005) 101-113
-
(2005)
Drug Design Rev. (On line)
, vol.2
, pp. 101-113
-
-
Menéndez-Arias, L.1
Matamoros, T.2
Deval, J.3
Canard, B.4
-
7
-
-
0033621167
-
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids
-
Sarafianos S.G., Das K., Clark Jr. A.D., Ding J., Boyer P.L., Hughes S.H., and Arnold E. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids. Proc. Natl Acad. Sci. USA 96 (1999) 10027-10032
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 10027-10032
-
-
Sarafianos, S.G.1
Das, K.2
Clark Jr., A.D.3
Ding, J.4
Boyer, P.L.5
Hughes, S.H.6
Arnold, E.7
-
8
-
-
0033165851
-
A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase
-
Meyer P.R., Matsuura S.E., Mian A.M., So A.G., and Scott W.A. A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase. Mol. Cell 4 (1999) 35-43
-
(1999)
Mol. Cell
, vol.4
, pp. 35-43
-
-
Meyer, P.R.1
Matsuura, S.E.2
Mian, A.M.3
So, A.G.4
Scott, W.A.5
-
9
-
-
0034425841
-
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2′-deoxynucleoside triphosphates
-
Meyer P.R., Matsuura S.E., Schinazi R.F., So A.G., and Scott W.A. Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2′-deoxynucleoside triphosphates. Antimicrob. Agents Chemother. 44 (2000) 3465-3472
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 3465-3472
-
-
Meyer, P.R.1
Matsuura, S.E.2
Schinazi, R.F.3
So, A.G.4
Scott, W.A.5
-
10
-
-
0035031936
-
Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase
-
Boyer P.L., Sarafianos S.G., Arnold E., and Hughes S.H. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase. J. Virol. 75 (2001) 4832-4842
-
(2001)
J. Virol.
, vol.75
, pp. 4832-4842
-
-
Boyer, P.L.1
Sarafianos, S.G.2
Arnold, E.3
Hughes, S.H.4
-
11
-
-
0034948070
-
Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants
-
Lennerstrand J., Hertogs K., Stammers D.K., and Larder B.A. Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants. J. Virol. 75 (2001) 7202-7205
-
(2001)
J. Virol.
, vol.75
, pp. 7202-7205
-
-
Lennerstrand, J.1
Hertogs, K.2
Stammers, D.K.3
Larder, B.A.4
-
12
-
-
0034947293
-
Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudine-associated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication
-
Naeger L.K., Margot N.A., and Miller M.D. Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudine-associated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication. Antivir. Ther. 6 (2001) 115-126
-
(2001)
Antivir. Ther.
, vol.6
, pp. 115-126
-
-
Naeger, L.K.1
Margot, N.A.2
Miller, M.D.3
-
13
-
-
0036233261
-
Effect of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase
-
Meyer P.R., Matsuura S.E., Tolun A.A., Pfeifer I., So A.G., Mellors J.W., and Scott W.A. Effect of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 46 (2002) 1540-1545
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 1540-1545
-
-
Meyer, P.R.1
Matsuura, S.E.2
Tolun, A.A.3
Pfeifer, I.4
So, A.G.5
Mellors, J.W.6
Scott, W.A.7
-
14
-
-
8544267978
-
Effects of primer-template sequence on ATP-dependent removal of chain terminating nucleotide analogues by HIV-1 reverse transcriptase
-
Meyer P.R., Smith A.J., Matsuura S.E., and Scott W.A. Effects of primer-template sequence on ATP-dependent removal of chain terminating nucleotide analogues by HIV-1 reverse transcriptase. J. Biol. Chem. 279 (2004) 45389-45398
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45389-45398
-
-
Meyer, P.R.1
Smith, A.J.2
Matsuura, S.E.3
Scott, W.A.4
-
15
-
-
0035984790
-
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase
-
Naeger L.K., Margot N.A., and Miller M.D. ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 46 (2002) 2179-2184
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 2179-2184
-
-
Naeger, L.K.1
Margot, N.A.2
Miller, M.D.3
-
16
-
-
0036406111
-
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors
-
Mas A., Vázquez-Álvarez B., Domingo E., and Menéndez-Arias L. Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. J. Mol. Biol. 323 (2002) 181-197
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 181-197
-
-
Mas, A.1
Vázquez-Álvarez, B.2
Domingo, E.3
Menéndez-Arias, L.4
-
17
-
-
0030987309
-
Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase
-
Tong W., Lu C.-D., Sharma S.K., Matsuura S., So A.G., and Scott W.A. Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase. Biochemistry 36 (1997) 5749-5757
-
(1997)
Biochemistry
, vol.36
, pp. 5749-5757
-
-
Tong, W.1
Lu, C.-D.2
Sharma, S.K.3
Matsuura, S.4
So, A.G.5
Scott, W.A.6
-
18
-
-
0042316944
-
Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase - Implications for polymerase translocation and drug resistance
-
Marchand B., and Götte M. Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase - Implications for polymerase translocation and drug resistance. J. Biol. Chem. 278 (2003) 35362-35372
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35362-35372
-
-
Marchand, B.1
Götte, M.2
-
19
-
-
0030840407
-
Mutations in the pol gene of human immunodeficiency virus type 1 in infected patients receiving didanosine and hydroxyurea combination therapy
-
De Antoni A., Foli A., Liscziewicz J., and Lori F. Mutations in the pol gene of human immunodeficiency virus type 1 in infected patients receiving didanosine and hydroxyurea combination therapy. J. Infect. Dis. 176 (1997) 899-903
-
(1997)
J. Infect. Dis.
, vol.176
, pp. 899-903
-
-
De Antoni, A.1
Foli, A.2
Liscziewicz, J.3
Lori, F.4
-
20
-
-
0032533207
-
A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors
-
Winters M.A., Coolley K.L., Girard Y.A., Levee D.J., Hamdan H., Shafer R.W., et al. A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. J. Clin. Invest. 102 (1998) 1769-1775
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1769-1775
-
-
Winters, M.A.1
Coolley, K.L.2
Girard, Y.A.3
Levee, D.J.4
Hamdan, H.5
Shafer, R.W.6
-
21
-
-
21444441862
-
Insertions in the human immunodeficiency virus type 1 protease and reverse transcriptase genes: clinical impact and molecular mechanisms
-
Winters M.A., and Merigan T.C. Insertions in the human immunodeficiency virus type 1 protease and reverse transcriptase genes: clinical impact and molecular mechanisms. Antimicrob. Agents Chemother. 49 (2005) 2575-2582
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 2575-2582
-
-
Winters, M.A.1
Merigan, T.C.2
-
22
-
-
33646528913
-
Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness
-
Menéndez-Arias L., Matamoros T., and Cases-González C.E. Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness. Curr. Pharm. Des. 12 (2006) 1811-1825
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 1811-1825
-
-
Menéndez-Arias, L.1
Matamoros, T.2
Cases-González, C.E.3
-
23
-
-
0033914679
-
Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues
-
Van Vaerenbergh K., van Laethem K., Albert J., Boucher C.A.B., Clotet B., Floridia M., et al. Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues. Antimicrob. Agents Chemother. 44 (2000) 2109-2117
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 2109-2117
-
-
Van Vaerenbergh, K.1
van Laethem, K.2
Albert, J.3
Boucher, C.A.B.4
Clotet, B.5
Floridia, M.6
-
24
-
-
33646440592
-
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations
-
Parikh U.M., Bacheler L., Koontz D., and Mellors J.W. The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations. J. Virol. 80 (2006) 4971-4977
-
(2006)
J. Virol.
, vol.80
, pp. 4971-4977
-
-
Parikh, U.M.1
Bacheler, L.2
Koontz, D.3
Mellors, J.W.4
-
25
-
-
0034329473
-
Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance
-
Mas A., Parera M., Briones C., Soriano V., Martínez M.A., Domingo E., and Menéndez-Arias L. Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance. EMBO J. 19 (2000) 5752-5761
-
(2000)
EMBO J.
, vol.19
, pp. 5752-5761
-
-
Mas, A.1
Parera, M.2
Briones, C.3
Soriano, V.4
Martínez, M.A.5
Domingo, E.6
Menéndez-Arias, L.7
-
26
-
-
3242735078
-
Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215
-
Prado J.G., Franco S., Matamoros T., Ruiz L., Clotet B., Menéndez-Arias L., et al. Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215. Virology 326 (2004) 103-112
-
(2004)
Virology
, vol.326
, pp. 103-112
-
-
Prado, J.G.1
Franco, S.2
Matamoros, T.3
Ruiz, L.4
Clotet, B.5
Menéndez-Arias, L.6
-
27
-
-
2642518791
-
Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain - Effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA primers
-
Matamoros T., Franco S., Vázquez-Álvarez B.M., Mas A., Martínez M.A., and Menéndez-Arias L. Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain - Effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA primers. J. Biol. Chem. 279 (2004) 24569-24577
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24569-24577
-
-
Matamoros, T.1
Franco, S.2
Vázquez-Álvarez, B.M.3
Mas, A.4
Martínez, M.A.5
Menéndez-Arias, L.6
-
28
-
-
0036720770
-
Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision
-
Boyer P.L., Sarafianos S.G., Arnold E., and Hughes S.H. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision. J. Virol. 76 (2002) 9143-9151
-
(2002)
J. Virol.
, vol.76
, pp. 9143-9151
-
-
Boyer, P.L.1
Sarafianos, S.G.2
Arnold, E.3
Hughes, S.H.4
-
29
-
-
0035822981
-
World-wide variation in HIV-1 phenotypic susceptibility in untreated individuals: biologically relevant values for resistance testing
-
Harrigan P.R., Montaner J.S.G., Wegner S.A., Verbiest W., Miller V., Wood R., and Larder B.A. World-wide variation in HIV-1 phenotypic susceptibility in untreated individuals: biologically relevant values for resistance testing. AIDS 15 (2001) 1671-1677
-
(2001)
AIDS
, vol.15
, pp. 1671-1677
-
-
Harrigan, P.R.1
Montaner, J.S.G.2
Wegner, S.A.3
Verbiest, W.4
Miller, V.5
Wood, R.6
Larder, B.A.7
-
30
-
-
0036135675
-
Comparative analysis of two commercial phenotypic assays for drug susceptibility testing of human immunodeficiency virus type 1
-
Qari S.H., Respess R., Weinstock H., Beltrami E.M., Hertogs K., Larder B.A., et al. Comparative analysis of two commercial phenotypic assays for drug susceptibility testing of human immunodeficiency virus type 1. J. Clin. Microbiol. 40 (2002) 31-35
-
(2002)
J. Clin. Microbiol.
, vol.40
, pp. 31-35
-
-
Qari, S.H.1
Respess, R.2
Weinstock, H.3
Beltrami, E.M.4
Hertogs, K.5
Larder, B.A.6
-
31
-
-
0042347690
-
Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis
-
Ray A.S., Murakami E., Basavapathruni A., Vaccaro J.A., Ulrich D., Chu C.K., et al. Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis. Biochemistry 42 (2003) 8831-8841
-
(2003)
Biochemistry
, vol.42
, pp. 8831-8841
-
-
Ray, A.S.1
Murakami, E.2
Basavapathruni, A.3
Vaccaro, J.A.4
Ulrich, D.5
Chu, C.K.6
-
32
-
-
18744365757
-
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA
-
Sarafianos S.G., Clark Jr. A.D., Das K., Tuske S., Birktoft J.J., Ilankumaran P., et al. Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. EMBO J. 21 (2002) 6614-6624
-
(2002)
EMBO J.
, vol.21
, pp. 6614-6624
-
-
Sarafianos, S.G.1
Clark Jr., A.D.2
Das, K.3
Tuske, S.4
Birktoft, J.J.5
Ilankumaran, P.6
-
33
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance
-
Huang H., Chopra R., Verdine G.L., and Harrison S.C. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science 282 (1998) 1669-1675
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
34
-
-
0032506228
-
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism
-
Meyer P.R., Matsuura S.E., So A.G., and Scott W.A. Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. Proc. Natl Acad. Sci. USA 95 (1998) 13471-13476
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 13471-13476
-
-
Meyer, P.R.1
Matsuura, S.E.2
So, A.G.3
Scott, W.A.4
-
35
-
-
13544271167
-
Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using α-boranophosphate nucleoside analogs
-
Deval J., Alvarez K., Selmi B., Bermond M., Boretto J., Guerreiro C., et al. Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using α-boranophosphate nucleoside analogs. J. Biol. Chem. 280 (2005) 3838-3846
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3838-3846
-
-
Deval, J.1
Alvarez, K.2
Selmi, B.3
Bermond, M.4
Boretto, J.5
Guerreiro, C.6
-
36
-
-
0029112612
-
Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase - Catalytic role and inhibitor sensitivity
-
Sarafianos S.G., Pandey V.N., Kaushik N., and Modak M.J. Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase - Catalytic role and inhibitor sensitivity. J. Biol. Chem. 270 (1995) 19729-19735
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19729-19735
-
-
Sarafianos, S.G.1
Pandey, V.N.2
Kaushik, N.3
Modak, M.J.4
-
37
-
-
0030664549
-
Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis
-
Kaushik N., Harris D., Rege N., Modak M.J., Yadav P.N.S., and Pandey V.N. Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis. Biochemistry 36 (1997) 14430-14438
-
(1997)
Biochemistry
, vol.36
, pp. 14430-14438
-
-
Kaushik, N.1
Harris, D.2
Rege, N.3
Modak, M.J.4
Yadav, P.N.S.5
Pandey, V.N.6
-
38
-
-
0032509209
-
Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase
-
Harris D., Kaushik N., Pandey P.K., Yadav P.N.S., and Pandey V.N. Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase. J. Biol. Chem. 273 (1998) 33624-33634
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33624-33634
-
-
Harris, D.1
Kaushik, N.2
Pandey, P.K.3
Yadav, P.N.S.4
Pandey, V.N.5
-
39
-
-
0036156325
-
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails
-
Mewshaw J.P., Myrick F.T., Wakefield D.A.C.S., Hooper B.J., Harris J.L., McCreedy B., and Borroto-Esoda K. Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails. J. Acquir. Immune Defic. Syndr. 29 (2002) 11-20
-
(2002)
J. Acquir. Immune Defic. Syndr.
, vol.29
, pp. 11-20
-
-
Mewshaw, J.P.1
Myrick, F.T.2
Wakefield, D.A.C.S.3
Hooper, B.J.4
Harris, J.L.5
McCreedy, B.6
Borroto-Esoda, K.7
-
40
-
-
0031948662
-
Altered drug sensitivity, fitness and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance
-
Maeda Y., Venzon D.J., and Mitsuya H. Altered drug sensitivity, fitness and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance. J. Infect. Dis. 177 (1998) 1207-1213
-
(1998)
J. Infect. Dis.
, vol.177
, pp. 1207-1213
-
-
Maeda, Y.1
Venzon, D.J.2
Mitsuya, H.3
-
41
-
-
0033064963
-
Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an in vitro competitive HIV-1 replication assay
-
Kosalaraksa P., Kavlick M.F., Maroun V., Le R., and Mitsuya H. Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an in vitro competitive HIV-1 replication assay. J. Virol. 73 (1999) 5356-5363
-
(1999)
J. Virol.
, vol.73
, pp. 5356-5363
-
-
Kosalaraksa, P.1
Kavlick, M.F.2
Maroun, V.3
Le, R.4
Mitsuya, H.5
-
42
-
-
0032817241
-
A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance
-
Larder B.A., Bloor S., Kemp S.D., Hertogs K., Desmet R.L., Miller V., et al. A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. Antimicrob. Agents Chemother. 43 (1999) 1961-1967
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 1961-1967
-
-
Larder, B.A.1
Bloor, S.2
Kemp, S.D.3
Hertogs, K.4
Desmet, R.L.5
Miller, V.6
-
43
-
-
0037334586
-
Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation
-
Meyer P.R., Lennerstrand J., Matsuura S.E., Larder B.A., and Scott W.A. Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation. J. Virol. 77 (2003) 3871-3877
-
(2003)
J. Virol.
, vol.77
, pp. 3871-3877
-
-
Meyer, P.R.1
Lennerstrand, J.2
Matsuura, S.E.3
Larder, B.A.4
Scott, W.A.5
-
44
-
-
13844312476
-
Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision
-
Nikolenko G.N., Palmer S., Maldarelli F., Mellors J.W., Coffin J.M., and Pathak V.K. Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision. Proc. Natl Acad. Sci. USA 102 (2005) 2093-2098
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2093-2098
-
-
Nikolenko, G.N.1
Palmer, S.2
Maldarelli, F.3
Mellors, J.W.4
Coffin, J.M.5
Pathak, V.K.6
-
45
-
-
33646519924
-
The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell
-
Smith A.J., and Scott W.A. The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell. Curr. Pharm. Des. 12 (2006) 1827-1841
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 1827-1841
-
-
Smith, A.J.1
Scott, W.A.2
-
46
-
-
0034019566
-
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1
-
Petropoulos C.J., Parkin N.T., Limoli K.L., Lie Y.S., Wrin T., Huang W., et al. A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 44 (2000) 920-928
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 920-928
-
-
Petropoulos, C.J.1
Parkin, N.T.2
Limoli, K.L.3
Lie, Y.S.4
Wrin, T.5
Huang, W.6
-
47
-
-
0027988547
-
Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy
-
Lin P.-F., Samanta H., Rose R.E., Patick A.K., Trimble J., Bechtold C.M., et al. Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy. J. Infect. Dis. 170 (1994) 1157-1164
-
(1994)
J. Infect. Dis.
, vol.170
, pp. 1157-1164
-
-
Lin, P.-F.1
Samanta, H.2
Rose, R.E.3
Patick, A.K.4
Trimble, J.5
Bechtold, C.M.6
-
48
-
-
0032693960
-
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine
-
Izopet J., Bicart-See A., Pasquier C., Sandres K., Bonnet E., Marchou B., et al. Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine. J. Med. Virol. 59 (1999) 507-511
-
(1999)
J. Med. Virol.
, vol.59
, pp. 507-511
-
-
Izopet, J.1
Bicart-See, A.2
Pasquier, C.3
Sandres, K.4
Bonnet, E.5
Marchou, B.6
-
49
-
-
0001822944
-
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine
-
Coakley E.P., Gillis J.M., and Hammer S.M. Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine. AIDS 14 (2000) F9-F15
-
(2000)
AIDS
, vol.14
-
-
Coakley, E.P.1
Gillis, J.M.2
Hammer, S.M.3
-
50
-
-
0036768696
-
Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial
-
Calvez V., Costagliola D., Descamps D., Yvon A., Collin G., Cécile A., et al. Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial. Antivir. Ther. 7 (2002) 211-218
-
(2002)
Antivir. Ther.
, vol.7
, pp. 211-218
-
-
Calvez, V.1
Costagliola, D.2
Descamps, D.3
Yvon, A.4
Collin, G.5
Cécile, A.6
-
51
-
-
0032701542
-
Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: survey of 787 sequences
-
Yahi N., Tamalet C., Tourrés C., Tivoli N., Ariasi F., Volot F., et al. Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: survey of 787 sequences. J. Clin. Microbiol. 37 (1999) 4099-4106
-
(1999)
J. Clin. Microbiol.
, vol.37
, pp. 4099-4106
-
-
Yahi, N.1
Tamalet, C.2
Tourrés, C.3
Tivoli, N.4
Ariasi, F.5
Volot, F.6
-
52
-
-
0034081772
-
Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine
-
Hanna G.J., Johnson V.A., Kuritzkes D.R., Richman D.D., Leigh-Brown A., Savara A.V., et al. Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine. J. Infect. Dis. 181 (2000) 904-911
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 904-911
-
-
Hanna, G.J.1
Johnson, V.A.2
Kuritzkes, D.R.3
Richman, D.D.4
Leigh-Brown, A.5
Savara, A.V.6
-
53
-
-
33745778007
-
Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1
-
Hu Z., Giguel F., Hatano H., Reid P., Lu J., and Kuritzkes D.R. Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1. J. Virol. 80 (2006) 7020-7027
-
(2006)
J. Virol.
, vol.80
, pp. 7020-7027
-
-
Hu, Z.1
Giguel, F.2
Hatano, H.3
Reid, P.4
Lu, J.5
Kuritzkes, D.R.6
-
54
-
-
33745781478
-
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
-
Svicher V., Sing T., Santoro M.M., Forbici F., Rodríguez-Barrios F., Bertoli A., et al. Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors. J. Virol. 80 (2006) 7186-7198
-
(2006)
J. Virol.
, vol.80
, pp. 7186-7198
-
-
Svicher, V.1
Sing, T.2
Santoro, M.M.3
Forbici, F.4
Rodríguez-Barrios, F.5
Bertoli, A.6
-
55
-
-
0345306634
-
Thymidine analogue reverse transcriptase inhibitors resistance mutation profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure
-
Marcelin A.-G., Delaugerre C., Wirden M., Viegas P., Simon A., Katlama C., and Calvez V. Thymidine analogue reverse transcriptase inhibitors resistance mutation profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure. J. Med. Virol. 72 (2004) 162-165
-
(2004)
J. Med. Virol.
, vol.72
, pp. 162-165
-
-
Marcelin, A.-G.1
Delaugerre, C.2
Wirden, M.3
Viegas, P.4
Simon, A.5
Katlama, C.6
Calvez, V.7
-
56
-
-
0029757502
-
Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis
-
Martín-Hernández A.M., Domingo E., and Menéndez-Arias L. Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis. EMBO J. 15 (1996) 4434-4442
-
(1996)
EMBO J.
, vol.15
, pp. 4434-4442
-
-
Martín-Hernández, A.M.1
Domingo, E.2
Menéndez-Arias, L.3
-
57
-
-
0039393614
-
Studies on the effects of truncating α-helix E′ of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis
-
Menéndez-Arias L. Studies on the effects of truncating α-helix E′ of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis. Biochemistry 37 (1998) 16636-16644
-
(1998)
Biochemistry
, vol.37
, pp. 16636-16644
-
-
Menéndez-Arias, L.1
-
58
-
-
0041145086
-
Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115
-
Martín-Hernández A.M., Gutiérrez-Rivas M., Domingo E., and Menéndez-Arias L. Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115. Nucl. Acids Res. 25 (1997) 1383-1389
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 1383-1389
-
-
Martín-Hernández, A.M.1
Gutiérrez-Rivas, M.2
Domingo, E.3
Menéndez-Arias, L.4
-
59
-
-
0040578732
-
Mutational analysis of Phe160 within the "palm" subdomain of human immunodeficiency virus type 1 reverse transcriptase
-
Gutiérrez-Rivas M., Ibáñez A., Martínez M.A., Domingo E., and Menéndez-Arias L. Mutational analysis of Phe160 within the "palm" subdomain of human immunodeficiency virus type 1 reverse transcriptase. J. Mol. Biol. 290 (1999) 615-625
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 615-625
-
-
Gutiérrez-Rivas, M.1
Ibáñez, A.2
Martínez, M.A.3
Domingo, E.4
Menéndez-Arias, L.5
-
60
-
-
0028085161
-
Recombinant virus assay: a rapid, phenotypic assay for assessment of drug susceptibility of human immunodeficiency virus type 1 isolates
-
Kellam P., and Larder B.A. Recombinant virus assay: a rapid, phenotypic assay for assessment of drug susceptibility of human immunodeficiency virus type 1 isolates. Antimicrob. Agents Chemother. 38 (1994) 23-30
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 23-30
-
-
Kellam, P.1
Larder, B.A.2
-
61
-
-
0023687234
-
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
-
Pauwels R., Balzarini J., Baba M., Snoeck R., Schols D., Herdewijn P., et al. Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J. Virol. Methods 20 (1988) 309-321
-
(1988)
J. Virol. Methods
, vol.20
, pp. 309-321
-
-
Pauwels, R.1
Balzarini, J.2
Baba, M.3
Snoeck, R.4
Schols, D.5
Herdewijn, P.6
|