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Volumn 72, Issue 6, 1998, Pages 5154-5164

Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy

Author keywords

[No Author keywords available]

Indexed keywords

RITONAVIR; SAQUINAVIR; VIRUS RNA; ZIDOVUDINE;

EID: 0031950370     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.6.5154-5164.1998     Document Type: Article
Times cited : (73)

References (49)
  • 1
    • 0026805986 scopus 로고
    • Persistence of azidothymidine-resistant human immunodeficiency virus type 1 RNA genotypes in posttreatment sera
    • Albert, J., J. Wahlberg, J. Lundeberg, S. Cox, E. Sandström, B. Wahren, and M. Uhlén. 1992. Persistence of azidothymidine-resistant human immunodeficiency virus type 1 RNA genotypes in posttreatment sera. J. Virol. 66:5627-5630.
    • (1992) J. Virol. , vol.66 , pp. 5627-5630
    • Albert, J.1    Wahlberg, J.2    Lundeberg, J.3    Cox, S.4    Sandström, E.5    Wahren, B.6    Uhlén, M.7
  • 2
    • 0027373308 scopus 로고
    • High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase
    • Boucher, C. A. B., N. Cammack, P. Schipper, R. Schuurman, P. Rouse, M. A. Wainberg, and J. M. Cameron. 1993. High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 37:2231-2234.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 2231-2234
    • Boucher, C.A.B.1    Cammack, N.2    Schipper, P.3    Schuurman, R.4    Rouse, P.5    Wainberg, M.A.6    Cameron, J.M.7
  • 4
    • 0004732998 scopus 로고    scopus 로고
    • Independent evolution of the env and pol genes of HIV-1 during zidovudine therapy
    • Brown, A. L. B., and A. Cleland. 1996. Independent evolution of the env and pol genes of HIV-1 during zidovudine therapy. AIDS 10:1067-1073.
    • (1996) AIDS , vol.10 , pp. 1067-1073
    • Brown, A.L.B.1    Cleland, A.2
  • 5
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin, J. M. 1995. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 267:483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 9
    • 0029980114 scopus 로고    scopus 로고
    • Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNa load suppression by zidovudine
    • deJong, M. D., J. Veenstra, N. I. Stilianakis, R. Schuurman, J. M. A. Lange, R. J. deBoer, and C. A. B. Boucher. 1996. Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine. Proc. Natl. Acad. Sci. USA 93:5501-5506.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5501-5506
    • DeJong, M.D.1    Veenstra, J.2    Stilianakis, N.I.3    Schuurman, R.4    Lange, J.M.A.5    Deboer, R.J.6    Boucher, C.A.B.7
  • 10
    • 0029164375 scopus 로고
    • Nonisotopic hybridization assay for determination of relative amounts of genotypic human immunodeficiency virus type 1 zidovudine resistance
    • Eastman, P. S., E. Boyer, L. Mole, J. Kolberg, M. Urdea, and M. Holodniy. 1995. Nonisotopic hybridization assay for determination of relative amounts of genotypic human immunodeficiency virus type 1 zidovudine resistance. J. Clin. Microbiol. 33:2777-2780.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 2777-2780
    • Eastman, P.S.1    Boyer, E.2    Mole, L.3    Kolberg, J.4    Urdea, M.5    Holodniy, M.6
  • 11
    • 0026542755 scopus 로고
    • In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine
    • Gao, Q., Z. X. Gu, M. A. Parniak, X. G. Li, and M. A. Wainberg. 1992. In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine. J. Virol. 66:12-19.
    • (1992) J. Virol. , vol.66 , pp. 12-19
    • Gao, Q.1    Gu, Z.X.2    Parniak, M.A.3    Li, X.G.4    Wainberg, M.A.5
  • 13
    • 0029798237 scopus 로고    scopus 로고
    • Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients
    • Havlir, D. V., S. Eastman, A. Gamst, and D. D. Richman. 1996. Nevirapine-resistant human immunodeficiency virus: kinetics of replication and estimated prevalence in untreated patients. J. Virol. 70:7894-7899.
    • (1996) J. Virol. , vol.70 , pp. 7894-7899
    • Havlir, D.V.1    Eastman, S.2    Gamst, A.3    Richman, D.D.4
  • 14
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho, D. D., A. U. Neumann, A. S. Perelson, W. Chen, J. M. Leonard, and M. Markowitz. 1995. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, A.U.2    Perelson, A.S.3    Chen, W.4    Leonard, J.M.5    Markowitz, M.6
  • 15
    • 0028014288 scopus 로고
    • Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor
    • Ho, D. D., T. Toyoshima, H. Mo, D. J. Kempf, D. Norbeck, C. M. Chen, N. E. Wideburg, S. K. Burt, J. W. Erickson, and M. K. Singh. 1994. Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor. J. Virol. 68:2016-2020.
    • (1994) J. Virol. , vol.68 , pp. 2016-2020
    • Ho, D.D.1    Toyoshima, T.2    Mo, H.3    Kempf, D.J.4    Norbeck, D.5    Chen, C.M.6    Wideburg, N.E.7    Burt, S.K.8    Erickson, J.W.9    Singh, M.K.10
  • 16
    • 0029019919 scopus 로고
    • Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy
    • Holodniy, M., L. Mole, D. Margolis, J. Moss, H. Dong, E. Boyer, M. Urdea, J. Kolberg, and S. Eastman. 1995. Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy. J. Virol. 69:3510-3516.
    • (1995) J. Virol. , vol.69 , pp. 3510-3516
    • Holodniy, M.1    Mole, L.2    Margolis, D.3    Moss, J.4    Dong, H.5    Boyer, E.6    Urdea, M.7    Kolberg, J.8    Eastman, S.9
  • 17
    • 0029824426 scopus 로고    scopus 로고
    • In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: Mutations, kinetics, and frequencies
    • Jacobsen, H., M. Hanggi, M. Ott, I. B. Duncan, S. Owen, M. Andreoni, S. Vella, and J. Mous. 1996. In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: mutations, kinetics, and frequencies. J. Infect. Dis. 173:1379-1387.
    • (1996) J. Infect. Dis. , vol.173 , pp. 1379-1387
    • Jacobsen, H.1    Hanggi, M.2    Ott, M.3    Duncan, I.B.4    Owen, S.5    Andreoni, M.6    Vella, S.7    Mous, J.8
  • 18
    • 0028843163 scopus 로고
    • Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959
    • Jacobsen, H., K. Yasargil, D. L. Winslow, J. C. Craig, A. Krohn, I. B. Duncan, and J. Mous. 1995. Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959. Virology 206:527-534.
    • (1995) Virology , vol.206 , pp. 527-534
    • Jacobsen, H.1    Yasargil, K.2    Winslow, D.L.3    Craig, J.C.4    Krohn, A.5    Duncan, I.B.6    Mous, J.7
  • 21
    • 0026036042 scopus 로고
    • Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes
    • Larder, B. A., P. Kellam, and S. D. Kemp. 1991. Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes. AIDS 5:137-144.
    • (1991) AIDS , vol.5 , pp. 137-144
    • Larder, B.A.1    Kellam, P.2    Kemp, S.D.3
  • 22
    • 0024310253 scopus 로고
    • Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
    • Larder, B. A., and S. D. Kemp. 1989. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246: 1155-1158.
    • (1989) Science , vol.246 , pp. 1155-1158
    • Larder, B.A.1    Kemp, S.D.2
  • 24
    • 0029075130 scopus 로고
    • Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
    • Mansky, L. M., and H. M. Temin. 1995. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J. Virol. 69:5087-5094.
    • (1995) J. Virol. , vol.69 , pp. 5087-5094
    • Mansky, L.M.1    Temin, H.M.2
  • 25
    • 0028854676 scopus 로고
    • Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor
    • Markowitz, M., H. Mo, D. J. Kempf, D. W. Norbeck, T. N. Bhat, J. W. Erickson, and D. D. Ho. 1995. Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor. J. Virol. 69:701-706.
    • (1995) J. Virol. , vol.69 , pp. 701-706
    • Markowitz, M.1    Mo, H.2    Kempf, D.J.3    Norbeck, D.W.4    Bhat, T.N.5    Erickson, J.W.6    Ho, D.D.7
  • 27
    • 0026564571 scopus 로고
    • Competition between zidovudine-sensitive and zidovudine-resistant strains of HIV
    • McLean, A. R., and M. A. Nowak. 1992. Competition between zidovudine-sensitive and zidovudine-resistant strains of HIV. AIDS 6:71-79.
    • (1992) AIDS , vol.6 , pp. 71-79
    • McLean, A.R.1    Nowak, M.A.2
  • 30
    • 0031581661 scopus 로고    scopus 로고
    • Anti-viral drug treatment: Dynamics of resistance in free virus and infected cell populations
    • Nowak, M. A., S. Bonhoeffer, G. M. Shaw, and R. M. May. 1997. Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations. J. Theor. Biol. 184:203-217.
    • (1997) J. Theor. Biol. , vol.184 , pp. 203-217
    • Nowak, M.A.1    Bonhoeffer, S.2    Shaw, G.M.3    May, R.M.4
  • 31
    • 0027219220 scopus 로고
    • In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease
    • Otto, M. J., S. Garber, D. L. Winslow, C. D. Reid, P. Aldrich, P. K. Jadhav, C. E. Patterson, C. N. Hodge, and Y. S. Cheng. 1993. In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease. Proc. Natl. Acad. Sci. USA 90:7543-7547.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7543-7547
    • Otto, M.J.1    Garber, S.2    Winslow, D.L.3    Reid, C.D.4    Aldrich, P.5    Jadhav, P.K.6    Patterson, C.E.7    Hodge, C.N.8    Cheng, Y.S.9
  • 35
    • 0024334170 scopus 로고
    • Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity
    • Peng, C., B. K. Ho, T. W. Chang, and N. T. Chang. 1989. Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity. J. Virol. 63:2550-2556.
    • (1989) J. Virol. , vol.63 , pp. 2550-2556
    • Peng, C.1    Ho, B.K.2    Chang, T.W.3    Chang, N.T.4
  • 36
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson, A. S., A. U. Neumann, M. Markowitz, J. M. Leonard, and D. D. Ho. 1996. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271:1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 41
    • 0030012398 scopus 로고    scopus 로고
    • Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538)
    • Schmit, J.-C., L. Ruiz, B. Clotet, A. Raventos, J. Tor, J. Leonard, J. Desmyter, E. de Clercq, and A.-M. Vandamme. 1996. Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538). AIDS 10:995-999.
    • (1996) AIDS , vol.10 , pp. 995-999
    • Schmit, J.-C.1    Ruiz, L.2    Clotet, B.3    Raventos, A.4    Tor, J.5    Leonard, J.6    Desmyter, J.7    De Clercq, E.8    Vandamme, A.-M.9
  • 43
    • 0027957898 scopus 로고
    • Long-term persistence of zidovudine resistance mutations in plasma isolates of human immunodeficiency virus type 1 of dideoxyinosine-treated patients removed from zidovudine therapy
    • Smith, M. S., K. L. Koerber, and J. S. Pagano. 1994. Long-term persistence of zidovudine resistance mutations in plasma isolates of human immunodeficiency virus type 1 of dideoxyinosine-treated patients removed from zidovudine therapy. J. Infect. Dis. 169:184-188.
    • (1994) J. Infect. Dis. , vol.169 , pp. 184-188
    • Smith, M.S.1    Koerber, K.L.2    Pagano, J.S.3
  • 45
    • 0031060375 scopus 로고    scopus 로고
    • Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model
    • Stilianakis, N. I., C. A. B. Boucher, M. D. De Jong, R. Van Leeuwen, R. Schuurman, and R. J. De Boer. 1997. Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model. J. Virol. 71:161-168.
    • (1997) J. Virol. , vol.71 , pp. 161-168
    • Stilianakis, N.I.1    Boucher, C.A.B.2    De Jong, M.D.3    Van Leeuwen, R.4    Schuurman, R.5    De Boer, R.J.6
  • 46
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
    • Tisdale, M., S. D. Kemp, N. R. Parry, and B. A. Larder. 1993. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc. Natl. Acad. Sci. USA 90:5653-5656.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parry, N.R.3    Larder, B.A.4
  • 47
    • 0029133978 scopus 로고
    • Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors
    • Tisdale, M., R. E. Myers, B. Maschera, N. R. Parry, N. M. Oliver, and E. D. Blair. 1995. Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors. Antimicrob. Agents Chemother. 39:1704-1710.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1704-1710
    • Tisdale, M.1    Myers, R.E.2    Maschera, B.3    Parry, N.R.4    Oliver, N.M.5    Blair, E.D.6


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