Role of innate immunity in acetaminophen-induced hepatotoxicity

Expert Opinion on Drug Metabolism and Toxicology

Volumn 2, Issue 4, 2006, Pages 493-503

  Liu, Zhang Xu ^a   Kaplowitz, Neil ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Acetaminophen; c Jun N terminal kinase; Chemokines; Cytokines; Hepatotoxicity; Inflammation; Innate immunity; Kupffer cells; Neutrophils; NK cells; NKT cells

Indexed keywords

GLUTATHIONE; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; ANALGESIC AGENT; CHEMOKINE; CYTOKINE;

ANTIINFLAMMATORY ACTIVITY; CELL STRESS; COVALENT BOND; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; DRUG EFFECT; DRUG SENSITIVITY; GENETIC REGULATION; HUMAN; INNATE IMMUNITY; LIVER TOXICITY; PROTEIN DEPLETION; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; UNITED STATES; ANIMAL; IMMUNOLOGY; LIVER; PATHOPHYSIOLOGY; PHYSIOLOGY; TOXIC HEPATITIS;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CHEMOKINES; CYTOKINES; HEPATITIS, TOXIC; HUMANS; IMMUNITY, NATURAL; LIVER;

EID: 33747834655     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2.4.493     Document Type: Review

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