Opposite roles of neutrophils and macrophages in the pathogenesis of acetaminophen-induced acute liver injury

European Journal of Immunology

Volumn 36, Issue 4, 2006, Pages 1028-1038

  Ishida, Yuko ^a,b   Kondo, Toshikazu ^b   Kimura, Akihiko ^b   Tsuneyama, Kouichi ^c   Takayasu, Tatsunori ^a   Mukaida, Naofumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Chemokine; Liver immunology; Macrophages; Neutrophils; Toxicology

Indexed keywords

ALANINE AMINOTRANSFERASE; CHEMOKINE RECEPTOR CXCR2; GRANULOCYTE ANTIBODY; HEME OXYGENASE 1; IMMUNOGLOBULIN G; INDUCIBLE NITRIC OXIDE SYNTHASE; PARACETAMOL; PROTOPORPHYRIN TIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; LIVER INJURY; LIVER NECROSIS; MACROPHAGE; MORTALITY; MOUSE; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; SURVIVAL; WILD TYPE;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HEME OXYGENASE-1; IMMUNOHISTOCHEMISTRY; LIVER DISEASES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, INTERLEUKIN-8B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33645950774     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535261     Document Type: Article

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