The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

Toxicology Letters

Volumn 144, Issue 3, 2003, Pages 279-288

  Jaeschke, Hartmut ^a   Knight, Tamara R ^a,b   Bajt, Mary Lynn ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Acetaminophen; Apoptosis; Liver cell necrosis; Oxidant stress; Peroxynitrite

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL PROTEIN; GLUTATHIONE; MITOCHONDRIAL PROTEIN; OXIDIZING AGENT; PARACETAMOL; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; SUPEROXIDE;

APOPTOSIS; CELL DEATH; CHRONIC TOXICITY; HUMAN; INHIBITION KINETICS; LIPID PEROXIDATION; LIVER CELL DAMAGE; LIVER TOXICITY; MACROMOLECULE; METABOLIC DISORDER; MITOCHONDRIAL RESPIRATION; NITRATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; REVIEW; TOXICOKINETICS;

ANIMALIA;

EID: 0043135016     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(03)00239-X     Document Type: Short Survey

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