-
1
-
-
0037180812
-
Inflammation: Points of control
-
Nathan, C. Inflammation: points of control. Nature 420, 846-852 (2002).
-
(2002)
Nature
, vol.420
, pp. 846-852
-
-
Nathan, C.1
-
2
-
-
0037365968
-
Specificity of a third kind: Reactive oxygen and nitrogen intermediates in cell signalling
-
Nathan, C. Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signalling. J. Clin. Invest 111, 769-778 (2003).
-
(2003)
J. Clin. Invest
, vol.111
, pp. 769-778
-
-
Nathan, C.1
-
3
-
-
0023140258
-
Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins
-
Henson, P. M. & Johnston, R. B. Jr. Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins. J. Clin. Invest. 79, 669-674 (1987).
-
(1987)
J. Clin. Invest.
, vol.79
, pp. 669-674
-
-
Henson, P.M.1
Johnston Jr., R.B.2
-
4
-
-
0024602827
-
Tissue destruction by neutrophils
-
Weiss, S. J. Tissue destruction by neutrophils. N. Engl. J. Med. 320, 365-376 (1989).
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 365-376
-
-
Weiss, S.J.1
-
5
-
-
0034619970
-
Immunodeficiency diseases caused by defects in phagocytes
-
Lekstrom-Himes, J. A. & Gallin, J. I. Immunodeficiency diseases caused by defects in phagocytes. N. Engl. J. Med. 343, 1703-1714 (2000).
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1703-1714
-
-
Lekstrom-Himes, J.A.1
Gallin, J.I.2
-
7
-
-
0034119167
-
Neutrophils: Molecules, functions and pathophysiological aspects
-
Witko-Sarsat, V., Rieu, P., Descamps-Latscha, B., Lesavre, P. & Halbwachs-Mecarelli, L. Neutrophils: molecules, functions and pathophysiological aspects. Lab. Invest. 80, 617-653 (2000).
-
(2000)
Lab. Invest.
, vol.80
, pp. 617-653
-
-
Witko-Sarsat, V.1
Rieu, P.2
Descamps-Latscha, B.3
Lesavre, P.4
Halbwachs-Mecarelli, L.5
-
8
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger, P. The danger model: a renewed sense of self. Science 296, 301-305 (2002).
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
9
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov, R. & Janeway, C. A. Jr. Decoding the patterns of self and nonself by the innate immune system. Science 296, 298-300 (2002).
-
(2002)
Science
, vol.296
, pp. 298-300
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
10
-
-
15544369658
-
Host-bacterial mutualism in the human intestine
-
Backhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A. & Gordon, J. I. Host-bacterial mutualism in the human intestine. Science 307, 1915-1920 (2005).
-
(2005)
Science
, vol.307
, pp. 1915-1920
-
-
Backhed, F.1
Ley, R.E.2
Sonnenburg, J.L.3
Peterson, D.A.4
Gordon, J.I.5
-
11
-
-
0030866891
-
Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils
-
Chertov, O. et al. Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils. J. Exp. Med. 186, 739-747 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 739-747
-
-
Chertov, O.1
-
12
-
-
0345690207
-
Cross-talk in the innate immune system: Neutrophils instruct recruitment and activation of dendritic cells during microbial infection
-
Bennouna, S., Bliss, S. K., Curiel, T. J. & Denkers, E. Y. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J. Immunol. 171, 6052-6058 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 6052-6058
-
-
Bennouna, S.1
Bliss, S.K.2
Curiel, T.J.3
Denkers, E.Y.4
-
13
-
-
4143115478
-
Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus
-
Tsuda, Y. et al. Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus. Immunity 21, 215-226 (2004).
-
(2004)
Immunity
, vol.21
, pp. 215-226
-
-
Tsuda, Y.1
-
14
-
-
21244502469
-
Neutrophil-mediated maturation of chemerin: A link between innate and adaptive immunity
-
Wittamer, V. et al. Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity. J. Immunol. 175, 487-493 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 487-493
-
-
Wittamer, V.1
-
15
-
-
18244389671
-
Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN
-
van Gisbergen, K. P., Sanchez-Hernandez, M., Geijtenbeek, T. B. & van Kooyk, Y. Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. J. Exp. Med. 201, 1281-1292 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1281-1292
-
-
Van Gisbergen, K.P.1
Sanchez-Hernandez, M.2
Geijtenbeek, T.B.3
Van Kooyk, Y.4
-
16
-
-
19944428744
-
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: Implications for inflammatory diseases
-
Scapini, P. et al. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood 105, 830-837 (2005).
-
(2005)
Blood
, vol.105
, pp. 830-837
-
-
Scapini, P.1
-
17
-
-
4944249660
-
Human neutrophils produce interferon-γ upon stimulation by interleukin-12
-
Ethuin, F. et al. Human neutrophils produce interferon-γ upon stimulation by interleukin-12. Lab. Invest. 84, 1363-1371 (2004).
-
(2004)
Lab. Invest.
, vol.84
, pp. 1363-1371
-
-
Ethuin, F.1
-
18
-
-
0035874990
-
Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
-
Schmielau, J. & Finn, O. J. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res. 61, 4756-4760 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 4756-4760
-
-
Schmielau, J.1
Finn, O.J.2
-
19
-
-
18444389451
-
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
-
Heissig, B. et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109, 625-637 (2002).
-
(2002)
Cell
, vol.109
, pp. 625-637
-
-
Heissig, B.1
-
20
-
-
0036800086
-
G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood
-
Semerad, C. L., Liu, F., Gregory, A. D., Stumpf, K. & Link, D. C. G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity 17, 413-423 (2002).
-
(2002)
Immunity
, vol.17
, pp. 413-423
-
-
Semerad, C.L.1
Liu, F.2
Gregory, A.D.3
Stumpf, K.4
Link, D.C.5
-
21
-
-
15244344110
-
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
-
Stark, M. A. et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22, 285-294 (2005).
-
(2005)
Immunity
, vol.22
, pp. 285-294
-
-
Stark, M.A.1
-
22
-
-
0031907920
-
Type 1 interferon (IFNα/β) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite
-
Diefenbach, A. et al. Type 1 interferon (IFNα/β) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite. Immunity 8, 77-87 (1998).
-
(1998)
Immunity
, vol.8
, pp. 77-87
-
-
Diefenbach, A.1
-
23
-
-
4444317346
-
Neutrophil function in the healing wound: Adding insult to injury?
-
Dovi, J. V., Szpaderska, A. M. & DiPietro, L. A. Neutrophil function in the healing wound: adding insult to injury? Thromb. Haemost. 92, 275-280 (2004).
-
(2004)
Thromb. Haemost.
, vol.92
, pp. 275-280
-
-
Dovi, J.V.1
Szpaderska, A.M.2
DiPietro, L.A.3
-
24
-
-
0038348096
-
Wound healing in the PU. 1 null mouse - Tissue repair is not dependent on inflammatory cells
-
Martin, P. et al. Wound healing in the PU. 1 null mouse - tissue repair is not dependent on inflammatory cells. Curr. Biol. 13, 1122-1128 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 1122-1128
-
-
Martin, P.1
-
26
-
-
0035544706
-
Hematologically important mutations: Leukocyte adhesion deficiency
-
Roos, D. & Law, S. K. Hematologically important mutations: leukocyte adhesion deficiency. Blood Cells Mol. Dis. 27, 1000-1004 (2001).
-
(2001)
Blood Cells Mol. Dis.
, vol.27
, pp. 1000-1004
-
-
Roos, D.1
Law, S.K.2
-
27
-
-
0141670816
-
LAD-III, a novel group of leukocyte integrin activation deficiencies
-
Alon, R. & Etzioni, A. LAD-III, a novel group of leukocyte integrin activation deficiencies. Trends Immunol. 24, 561-566 (2003).
-
(2003)
Trends Immunol.
, vol.24
, pp. 561-566
-
-
Alon, R.1
Etzioni, A.2
-
28
-
-
0023484511
-
Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes
-
Nathan, C. F. Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. J. Clin. Invest. 80, 1550-1560 (1987).
-
(1987)
J. Clin. Invest.
, vol.80
, pp. 1550-1560
-
-
Nathan, C.F.1
-
29
-
-
11044221394
-
Novel ω-3-derived local mediators in anti-inflammation and resolution
-
Serhan, C. N. Novel ω-3-derived local mediators in anti-inflammation and resolution. Pharmacol. Ther. 105, 7-21 (2005).
-
(2005)
Pharmacol. Ther.
, vol.105
, pp. 7-21
-
-
Serhan, C.N.1
-
30
-
-
0030941175
-
Secretory leukocyte protease inhibitor: A macrophage product induced by and antagonistic to bacterial lipopolysaccharide
-
Jin, F. Y., Nathan, C., Radzioch, D. & Ding, A. Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell 88, 417-426 (1997).
-
(1997)
Cell
, vol.88
, pp. 417-426
-
-
Jin, F.Y.1
Nathan, C.2
Radzioch, D.3
Ding, A.4
-
31
-
-
0037074016
-
Conversion of proepithelin to epithelins: Roles of SLPI and elastase in host defense and wound repair
-
Zhu, J. et al. Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell 111, 867-878 (2002).
-
(2002)
Cell
, vol.111
, pp. 867-878
-
-
Zhu, J.1
-
32
-
-
0034075048
-
Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia
-
Grobmyer, S. R. et al. Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia. Crit. Care Med. 28, 1276-1282 (2000).
-
(2000)
Crit. Care Med.
, vol.28
, pp. 1276-1282
-
-
Grobmyer, S.R.1
-
33
-
-
0037329891
-
Progranulin is a mediator of the wound response
-
He, Z., Ong, C. H., Halper, J. & Bateman, A. Progranulin is a mediator of the wound response. Nature Med. 9, 225-229 (2003).
-
(2003)
Nature Med.
, vol.9
, pp. 225-229
-
-
He, Z.1
Ong, C.H.2
Halper, J.3
Bateman, A.4
-
34
-
-
18244390487
-
Myeloperoxidase: Friend and foe
-
Klebanoff, S. J. Myeloperoxidase: friend and foe. J. Leukoc. Biol. 77, 598-625 (2005).
-
(2005)
J. Leukoc. Biol.
, vol.77
, pp. 598-625
-
-
Klebanoff, S.J.1
-
35
-
-
8444249576
-
The acquired immune system: A vantage from beneath
-
Hedrick, S. M. The acquired immune system: a vantage from beneath. Immunity 21, 607-615 (2004).
-
(2004)
Immunity
, vol.21
, pp. 607-615
-
-
Hedrick, S.M.1
-
36
-
-
22944461763
-
Inborn errors of immunity to infection: The rule rather than the exception
-
Casanova, J. L. & Abel, L. Inborn errors of immunity to infection: the rule rather than the exception. J. Exp. Med. 202, 197-201 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 197-201
-
-
Casanova, J.L.1
Abel, L.2
-
37
-
-
20444411648
-
The moving frontier in nitric oxide-dependent signalling
-
2 Nov 2004 (doi: 10.1126/stke. 2572004pe2572052)
-
Nathan, C. The moving frontier in nitric oxide-dependent signalling. Sci. STKE 2 Nov 2004 (doi: 10.1126/stke. 2572004pe2572052).
-
Sci. STKE
-
-
Nathan, C.1
-
38
-
-
0026629902
-
Nitric oxide as a secretory product of mammalian cells
-
Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB. J. 6, 3051-3064 (1992).
-
(1992)
FASEB. J.
, vol.6
, pp. 3051-3064
-
-
Nathan, C.1
-
39
-
-
20444400257
-
Redox redux: Revisiting PTPs and the control of cell signalling
-
Tonks, N. K. Redox redux: revisiting PTPs and the control of cell signalling. Cell 121, 667-670 (2005).
-
(2005)
Cell
, vol.121
, pp. 667-670
-
-
Tonks, N.K.1
-
40
-
-
0037062477
-
A critical concentration of neutrophils is required for effective bacterial killing in suspension
-
Li, Y., Karlin, A., Loike, J. D. & Silverstein, S. C. A critical concentration of neutrophils is required for effective bacterial killing in suspension. Proc. Natl Acad. Sci. USA 99, 8289-8294 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8289-8294
-
-
Li, Y.1
Karlin, A.2
Loike, J.D.3
Silverstein, S.C.4
-
41
-
-
0029438387
-
Granulocyte clearance by apoptosis in the resolution of inflammation
-
Savill, J. & Haslett, C. Granulocyte clearance by apoptosis in the resolution of inflammation. Semin. Cell Biol. 6, 385-393 (1995).
-
(1995)
Semin. Cell Biol.
, vol.6
, pp. 385-393
-
-
Savill, J.1
Haslett, C.2
-
42
-
-
22144492953
-
HIF-1 α expression regulates the bactericidal capacity of phagocytes
-
Peyssonnaux, C. et al. HIF-1 α expression regulates the bactericidal capacity of phagocytes. J. Clin. Invest. 115, 1806-1815 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1806-1815
-
-
Peyssonnaux, C.1
-
43
-
-
19944432390
-
Hypoxia-induced neutrophil survival is mediated by HIF-1 α-dependent NF-κB activity
-
Walmsley, S. R. et al. Hypoxia-induced neutrophil survival is mediated by HIF-1 α-dependent NF-κB activity. J. Exp. Med. 201, 105-115 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 105-115
-
-
Walmsley, S.R.1
-
44
-
-
20944443597
-
Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
-
Jonsson, H., Allen, P. & Peng, S. L. Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis. Nature Med. 11, 666-671 (2005).
-
(2005)
Nature Med.
, vol.11
, pp. 666-671
-
-
Jonsson, H.1
Allen, P.2
Peng, S.L.3
-
45
-
-
2542466891
-
Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils
-
Altznauer, F. et al. Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. J. Exp. Med. 199, 1343-1354 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1343-1354
-
-
Altznauer, F.1
-
46
-
-
11144314814
-
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
-
Flo, T. H. et al. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432, 917-921 (2004).
-
(2004)
Nature
, vol.432
, pp. 917-921
-
-
Flo, T.H.1
-
47
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann, V. et al. Neutrophil extracellular traps kill bacteria. Science 303, 1532-1535 (2004).
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
-
48
-
-
2942748480
-
Calprotectin- a pleiotropic molecule in acute and chronic inflammation
-
Striz, I. & Trebichavsky, I. Calprotectin- a pleiotropic molecule in acute and chronic inflammation. Physiol. Res. 53, 245-253 (2004).
-
(2004)
Physiol. Res.
, vol.53
, pp. 245-253
-
-
Striz, I.1
Trebichavsky, I.2
-
49
-
-
0025240360
-
Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate
-
Wright, G. W., Ooi, C. E., Weiss, J. & Elsbach, P. Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate. J. Biol. Chem. 265, 6675-6681 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 6675-6681
-
-
Wright, G.W.1
Ooi, C.E.2
Weiss, J.3
Elsbach, P.4
-
50
-
-
0242713072
-
Neutrophil granules and secretory vesicles in inflammation
-
Faurschou, M. & Borregaard, N. Neutrophil granules and secretory vesicles in inflammation. Microbes Infect. 5, 1317-1327 (2003).
-
(2003)
Microbes Infect.
, vol.5
, pp. 1317-1327
-
-
Faurschou, M.1
Borregaard, N.2
-
51
-
-
20644462344
-
Mammalian defensins in the antimicrobial immune response
-
Selsted, M. E. & Ouellette, A. J. Mammalian defensins in the antimicrobial immune response. Nature Immunol. 6, 551-557 (2005).
-
(2005)
Nature Immunol.
, vol.6
, pp. 551-557
-
-
Selsted, M.E.1
Ouellette, A.J.2
-
52
-
-
0017804093
-
Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes
-
Weiss, J., Elsbach, P., Olsson, I. & Odeberg, H. Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes. J. Biol. Chem. 253, 2664-2672 (1978).
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 2664-2672
-
-
Weiss, J.1
Elsbach, P.2
Olsson, I.3
Odeberg, H.4
-
53
-
-
0025239075
-
Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties
-
Campanelli, D., Detmers, P. A., Nathan, C. F. & Gabay, J. E. Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. J. Clin. Invest. 85, 904-915 (1990).
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 904-915
-
-
Campanelli, D.1
Detmers, P.A.2
Nathan, C.F.3
Gabay, J.E.4
-
54
-
-
0025310338
-
CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity
-
Pereira, H. A., Shafer, W. M., Pohl, J., Martin, L. E. & Spitznagel, J. K. CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity. J. Clin. Invest. 85, 1468-1476 (1990).
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 1468-1476
-
-
Pereira, H.A.1
Shafer, W.M.2
Pohl, J.3
Martin, L.E.4
Spitznagel, J.K.5
-
55
-
-
0014691242
-
Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
-
McCord, J. M. & Fridovich, I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 244, 6049-6055 (1969).
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
56
-
-
0015596284
-
Biological defense mechanisms. the production by leukocytes of superoxide, a potential bactericidal agent
-
Babior, B. M., Kipnes, R. S. & Curnutte, J. T. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest. 52, 741-744 (1973).
-
(1973)
J. Clin. Invest.
, vol.52
, pp. 741-744
-
-
Babior, B.M.1
Kipnes, R.S.2
Curnutte, J.T.3
-
57
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth, J. D. NOX enzymes and the biology of reactive oxygen. Nature Rev. Immunol. 4, 181-189 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
58
-
-
0014311555
-
Fatal (chronic) granulomatous disease of childhood: A hereditary defect of leukocyte function
-
Good, R. A. et al. Fatal (chronic) granulomatous disease of childhood: a hereditary defect of leukocyte function. Semin. Hematol. 5, 215-254 (1968).
-
(1968)
Semin. Hematol.
, vol.5
, pp. 215-254
-
-
Good, R.A.1
-
59
-
-
0037149510
-
+ flux
-
+ flux. Nature 416, 291-297 (2002).
-
(2002)
Nature
, vol.416
, pp. 291-297
-
-
Reeves, E.P.1
-
60
-
-
0242460542
-
Oxidative killing of microbes by neutrophils
-
Roos, D., van Bruggen, R. & Meischl, C. Oxidative killing of microbes by neutrophils. Microbes Infect. 5, 1307-1315 (2003).
-
(2003)
Microbes Infect.
, vol.5
, pp. 1307-1315
-
-
Roos, D.1
Van Bruggen, R.2
Meischl, C.3
-
61
-
-
0032984248
-
Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase
-
Shiloh, M. U. et al. Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. Immunity 10, 29-38 (1999).
-
(1999)
Immunity
, vol.10
, pp. 29-38
-
-
Shiloh, M.U.1
-
62
-
-
0036802316
-
MRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils
-
Staudinger, B. J., Oberdoerster, M. A., Lewis, P. J. & Rosen, H. mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils. J. Clin. Invest. 110, 1151-1163 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1151-1163
-
-
Staudinger, B.J.1
Oberdoerster, M.A.2
Lewis, P.J.3
Rosen, H.4
-
63
-
-
22944462082
-
Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity
-
Liu, G. Y. et al. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J. Exp. Med. 202, 209-215 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 209-215
-
-
Liu, G.Y.1
-
64
-
-
0024595405
-
Respiratory burst in adherent human neutrophils: Triggering by colony-stimulating factors CSF-GM and CSF-G
-
Nathan, C. F. Respiratory burst in adherent human neutrophils: triggering by colony-stimulating factors CSF-GM and CSF-G. Blood 73, 301-306 (1989).
-
(1989)
Blood
, vol.73
, pp. 301-306
-
-
Nathan, C.F.1
-
65
-
-
0023841073
-
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties
-
Wolpe, S. D. et al. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J. Exp. Med. 167, 570-581 (1988).
-
(1988)
J. Exp. Med.
, vol.167
, pp. 570-581
-
-
Wolpe, S.D.1
-
66
-
-
0024444326
-
Cytokine-induced respiratory burst of human neutrophils: Dependence on extracellular matrix proteins and CD11/CD18 integrins
-
Nathan, C. et al. Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. J. Cell. Biol. 109, 1341-1349 (1989).
-
(1989)
J. Cell. Biol.
, vol.109
, pp. 1341-1349
-
-
Nathan, C.1
-
67
-
-
0025719982
-
Cytokines in context
-
Nathan, C. & Sporn, M. Cytokines in context. J. Cell Biol. 113, 981-986 (1991).
-
(1991)
J. Cell Biol.
, vol.113
, pp. 981-986
-
-
Nathan, C.1
Sporn, M.2
-
69
-
-
0033555864
-
Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck
-
Mocsai, A., Ligeti, E., Lowell, C. A. & Berton, G. Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck. J. Immunol. 162, 1120-1126 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 1120-1126
-
-
Mocsai, A.1
Ligeti, E.2
Lowell, C.A.3
Berton, G.4
-
70
-
-
0032752657
-
Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF
-
Fuortes, M., Melchior, M., Han, H., Lyon, G. J. & Nathan, C. Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. J. Clin. Invest. 104, 327-335 (1999).
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 327-335
-
-
Fuortes, M.1
Melchior, M.2
Han, H.3
Lyon, G.J.4
Nathan, C.5
-
71
-
-
0036231179
-
Syk is required for integrin signalling in neutrophils
-
Mocsai, A., Zhou, M., Meng, F, Tybulewicz, V. L. & Lowell, C. A. Syk is required for integrin signalling in neutrophils. Immunity 16, 547-558 (2002).
-
(2002)
Immunity
, vol.16
, pp. 547-558
-
-
Mocsai, A.1
Zhou, M.2
Meng, F.3
Tybulewicz, V.L.4
Lowell, C.A.5
-
72
-
-
0031568669
-
Signalling by adhesion in human neutrophils: Activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophils spreading over fibrinogen
-
Yan, S. R., Huang, M. & Berton, G. Signalling by adhesion in human neutrophils: activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophils spreading over fibrinogen. J. Immunol. 158, 1902-1910 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 1902-1910
-
-
Yan, S.R.1
Huang, M.2
Berton, G.3
-
73
-
-
0034741265
-
TNFα elicits association of PI3-kinase with the p60TNFR and activation of PI3-kinase in adherent neutrophils
-
Korchak, H. M. & Kilpatrick, L. E. TNFα elicits association of PI3-kinase with the p60TNFR and activation of PI3-kinase in adherent neutrophils. Biochem. Biophys. Res. Commun. 281, 651-656 (2001).
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 651-656
-
-
Korchak, H.M.1
Kilpatrick, L.E.2
-
74
-
-
0346690398
-
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils
-
Zhao, T., Benard, V., Bohl, B. P. & Bokoch, G. M. The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. J. Clin. Invest. 112, 1732-1740 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1732-1740
-
-
Zhao, T.1
Benard, V.2
Bohl, B.P.3
Bokoch, G.M.4
-
75
-
-
3342903325
-
2 integrin-dependent functions of neutrophils
-
2 integrin-dependent functions of neutrophils. J. Cell Biol. 166, 273-282 (2004).
-
(2004)
J. Cell Biol.
, vol.166
, pp. 273-282
-
-
Gakidis, M.A.1
-
76
-
-
0027455465
-
Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumour necrosis factor
-
Fuortes, M., Jin, W. W. & Nathan, C. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumour necrosis factor. J. Cell Biol. 120, 777-784 (1993).
-
(1993)
J. Cell Biol.
, vol.120
, pp. 777-784
-
-
Fuortes, M.1
Jin, W.W.2
Nathan, C.3
-
77
-
-
0028170990
-
2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumour necrosis factor
-
2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumour necrosis factor. J. Cell Biol. 127, 1477-1483 (1994).
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1477-1483
-
-
Fuortes, M.1
Jin, W.W.2
Nathan, C.3
-
78
-
-
0027298857
-
Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin)
-
äé Jin, W. W. Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin). J. Cell Biol. 122, 243-256 (1993).
-
(1993)
J. Cell Biol.
, vol.122
, pp. 243-256
-
-
Nathan, C.1
Xie, Q.W.2
Halbwachs-Mecarelli, L.3
Jin, W.W.4
-
79
-
-
20444433960
-
Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
-
Raptis, S. Z., Shapiro, S. D., Simmons, P. M., Cheng, A. M. & Pham, C. T. Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering. Immunity 22, 679-691 (2005).
-
(2005)
Immunity
, vol.22
, pp. 679-691
-
-
Raptis, S.Z.1
Shapiro, S.D.2
Simmons, P.M.3
Cheng, A.M.4
Pham, C.T.5
-
81
-
-
0027470690
-
Recombinant human tumour necrosis factor α induces calcium oscillation and calcium-activated chloride current in human neutrophils. the role of calcium/ calmodulin-dependent protein kinase
-
Schumann, M. A., Gardner, P. & Raffin, T. A. Recombinant human tumour necrosis factor α induces calcium oscillation and calcium-activated chloride current in human neutrophils. The role of calcium/ calmodulin-dependent protein kinase. J. Biol. Chem. 268, 2134-2140 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2134-2140
-
-
Schumann, M.A.1
Gardner, P.2
Raffin, T.A.3
-
82
-
-
23744489145
-
Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils
-
Han, H. et al. Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. J. Exp. Med. 202, 353-361 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 353-361
-
-
Han, H.1
-
83
-
-
0027484041
-
Actin dynamics in human neutrophils during adhesion and phagocytosis is controlled by changes in intracellular free calcium
-
Bengtsson, T. et al. Actin dynamics in human neutrophils during adhesion and phagocytosis is controlled by changes in intracellular free calcium. Eur. J. Cell. Biol. 62, 49-58 (1993).
-
(1993)
Eur. J. Cell. Biol.
, vol.62
, pp. 49-58
-
-
Bengtsson, T.1
-
84
-
-
0037240676
-
Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumour necrosis factor: Separation of signals for the respiratory burst and degranulation
-
Han, H., Fuortes, M. & Nathan, C. Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumour necrosis factor: separation of signals for the respiratory burst and degranulation. J. Exp. Med. 197, 63-75 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 63-75
-
-
Han, H.1
Fuortes, M.2
Nathan, C.3
-
85
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M. & Werb, Z. Inflammation and cancer. Nature 420, 860-867 (2002).
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
86
-
-
0009535079
-
Synergy between tumour necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice
-
Rothstein, J. L. & Schreiber, H. Synergy between tumour necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice. Proc. Natl Acad. Sci. USA 85, 607-611 (1988).
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 607-611
-
-
Rothstein, J.L.1
Schreiber, H.2
-
87
-
-
0024502120
-
Murine interleukin-4 displays potent anti-tumour activity in vivo
-
Tepper, R. I., Pattengale, P. K. & Leder, P. Murine interleukin-4 displays potent anti-tumour activity in vivo. Cell 57, 503-512 (1989).
-
(1989)
Cell
, vol.57
, pp. 503-512
-
-
Tepper, R.I.1
Pattengale, P.K.2
Leder, P.3
-
88
-
-
0027163179
-
Regression of an established tumour genetically modified to release granulocyte colony-stimulating factor requires granulocyte-T-cell cooperation and T cell-produced interferon γ
-
Stoppacciaro, A. et al. Regression of an established tumour genetically modified to release granulocyte colony-stimulating factor requires granulocyte-T-cell cooperation and T cell-produced interferon γ. J. Exp. Med. 178, 151-161 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 151-161
-
-
Stoppacciaro, A.1
-
89
-
-
0032573225
-
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumour immunity in patients with metastatic melanoma
-
Soiffer, R. et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumour immunity in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 95, 13141-13146 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 13141-13146
-
-
Soiffer, R.1
-
90
-
-
0027976678
-
Hemorrhagic tumour necrosis during a pilot trial of tumour necrosis factor-α and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma
-
Minasian, L. M. et al. Hemorrhagic tumour necrosis during a pilot trial of tumour necrosis factor-α and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma. Blood 83, 56-64 (1994).
-
(1994)
Blood
, vol.83
, pp. 56-64
-
-
Minasian, L.M.1
-
92
-
-
22844438117
-
Progressive multifocal leukoencephalopathy and natalizumab - Unforeseen consequences
-
Berger, J. R. & Koralnik, I. J. Progressive multifocal leukoencephalopathy and natalizumab - unforeseen consequences. N. Engl. J. Med. 353, 414-416 (2005).
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 414-416
-
-
Berger, J.R.1
Koralnik, I.J.2
-
93
-
-
22844445230
-
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
-
Langer-Gould, A., Atlas, S. W., Green, A. J., Bollen, A. W. & Pelletier, D. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N. Engl. J. Med. 353, 375-381 (2005).
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 375-381
-
-
Langer-Gould, A.1
Atlas, S.W.2
Green, A.J.3
Bollen, A.W.4
Pelletier, D.5
-
94
-
-
22844439662
-
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon β-1 a for multiple sclerosis
-
Kleinschmidt-DeMasters, B. K. & Tyler, K. L. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon β-1 a for multiple sclerosis. N. Engl. J. Med. 353, 369-374 (2005).
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 369-374
-
-
Kleinschmidt-DeMasters, B.K.1
Tyler, K.L.2
-
95
-
-
8944254696
-
MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: A double-blind, randomized, placebo-controlled clinical trial
-
Luisetti, M. et al. MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled clinical trial. Eur. Respir. J. 9, 1482-1486 (1996).
-
(1996)
Eur. Respir. J.
, vol.9
, pp. 1482-1486
-
-
Luisetti, M.1
-
96
-
-
24044436201
-
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: Molecular mechanisms and anti-inflammatory activity in vivo
-
de Garavilla, L. et al. A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J. Biol. Chem. 280, 18001-18007 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18001-18007
-
-
De Garavilla, L.1
|