메뉴 건너뛰기




Volumn 279, Issue 3, 1996, Pages 1470-1483

Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CELL DNA; CHOLESTEROL HYDROGEN SUCCINATE; PARACETAMOL;

EID: 0030434801     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (183)

References (95)
  • 1
    • 0028238284 scopus 로고
    • Liver cell death: Patterns and mechanisms
    • ALISON, M. R. AND SARRAF, C. E.: Liver cell death: Patterns and mechanisms. Gut 35: 577-581, 1994.
    • (1994) Gut , vol.35 , pp. 577-581
    • Alison, M.R.1    Sarraf, C.E.2
  • 3
    • 0025774993 scopus 로고
    • Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes
    • BURCHAM, P. C. AND HARMAN, A. W.: Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes. J. Biol. Chem. 266: 5049-5054, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 5049-5054
    • Burcham, P.C.1    Harman, A.W.2
  • 4
    • 77957186430 scopus 로고
    • DMBA induces programmed cell death (apoptosis) in the A20.1 murine B cell lymphoma
    • BURCHIEL, S. W., DAVIS, D. A. P., RAY, S. D. AND BARTON, S. L.: DMBA induces programmed cell death (apoptosis) in the A20.1 murine B cell lymphoma. Fund. Appl. Toxicol. 21: 120-124, 1993.
    • (1993) Fund. Appl. Toxicol. , vol.21 , pp. 120-124
    • Burchiel, S.W.1    Davis, D.A.P.2    Ray, S.D.3    Barton, S.L.4
  • 5
    • 0026581758 scopus 로고
    • DMBA -induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: Relation of cell death to target cell intracellular calcium and DNA damage
    • BURCHIEL, S. W., DAVIS, D. A. P., RAY, S. D., ARCHULETA, M. M. THILSTEAD, J. P. AND CORCORAN, G. B.: DMBA -induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: Relation of cell death to target cell intracellular calcium and DNA damage. Toxicol. Appl. Pharmacol. 113: 126-132, 1992.
    • (1992) Toxicol. Appl. Pharmacol. , vol.113 , pp. 126-132
    • Burchiel, S.W.1    Davis, D.A.P.2    Ray, S.D.3    Archuleta, M.M.4    Thilstead, J.P.5    Corcoran, G.B.6
  • 6
    • 0025272539 scopus 로고
    • Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats
    • BURSCH, W., PAFFE, S., PUTZ, B., BARTHEL, G. AND SCHULTE-HERMAN, R.: Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis 11: 847-851, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 847-851
    • Bursch, W.1    Paffe, S.2    Putz, B.3    Barthel, G.4    Schulte-Herman, R.5
  • 7
    • 6544229829 scopus 로고
    • A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
    • BURTON, K.: A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62: 315-322, 1956.
    • (1956) Biochem. J. , vol.62 , pp. 315-322
    • Burton, K.1
  • 8
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • BUTTKE, T. M. AND SANDSTROM, P. A.: Oxidative stress as a mediator of apoptosis. Immunol. Today 15: 7-10, 1994.
    • (1994) Immunol. Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 9
    • 0025804702 scopus 로고
    • The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes
    • CANNON, J. R., HARVISON, P. J. AND RUSH, G. F.: The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. Toxicol. Appl. Pharm. 108: 407-416, 1991.
    • (1991) Toxicol. Appl. Pharm. , vol.108 , pp. 407-416
    • Cannon, J.R.1    Harvison, P.J.2    Rush, G.F.3
  • 10
    • 0018572128 scopus 로고
    • Ischemic myocardial cell injury: Prevention by chlorpromazine of an accelerated phospholipid degradation and associated membrane dysfunction
    • CHIEN, K. R., PFAU, R. G. AND FARBER, J. L.: Ischemic myocardial cell injury: Prevention by chlorpromazine of an accelerated phospholipid degradation and associated membrane dysfunction. Am. J. Pathol. 97: 505-530, 1979.
    • (1979) Am. J. Pathol. , vol.97 , pp. 505-530
    • Chien, K.R.1    Pfau, R.G.2    Farber, J.L.3
  • 11
    • 0014237396 scopus 로고
    • Acidophillic bodies: Their chemical and physical nature in patients with bolivian hemorrhagic fever
    • CHILD, P. AND RUIZ, L. A.: Acidophillic bodies: their chemical and physical nature in patients with bolivian hemorrhagic fever. Arch. Pathol. 85: 45-50, 1968.
    • (1968) Arch. Pathol. , vol.85 , pp. 45-50
    • Child, P.1    Ruiz, L.A.2
  • 13
    • 0026555808 scopus 로고
    • Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis
    • COLLINS, R. J., HARMON, B. V., GOBE, G. C. AND KERR, J. F. R.: Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int. J. Rad. Biol. 61: 451-453, 1992.
    • (1992) Int. J. Rad. Biol. , vol.61 , pp. 451-453
    • Collins, R.J.1    Harmon, B.V.2    Gobe, G.C.3    Kerr, J.F.R.4
  • 14
    • 0026766118 scopus 로고
    • Contemporary issues in toxicology. The role of nucleus and other compartnents in toxic cell death produced by alkylating hepatotoxicants
    • CORCORAN, G. B. AND RAY, S. D.: Contemporary issues in toxicology. The role of nucleus and other compartnents in toxic cell death produced by alkylating hepatotoxicants. Tox. Appl. Pharm. 113: 167-183, 1992.
    • (1992) Tox. Appl. Pharm. , vol.113 , pp. 167-183
    • Corcoran, G.B.1    Ray, S.D.2
  • 15
    • 0021345926 scopus 로고
    • N-acetyl-p-benzoquinoneimine: A cytochrome P-450 mediated oxidation product of acetaminophen
    • DAHLIN, D. C., MIWA, G. T., LU, A. Y. H. AND NELSON, S. D.: N-acetyl-p-benzoquinoneimine: A cytochrome P-450 mediated oxidation product of acetaminophen. Proc. Natl. Acad. Sci. U.S.A. 81: 1327-1331, 1984.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 1327-1331
    • Dahlin, D.C.1    Miwa, G.T.2    Lu, A.Y.H.3    Nelson, S.D.4
  • 16
    • 0014029813 scopus 로고
    • Acute liver necrosis following overdose of paracetamol
    • DAVIDSON, D. G. D. AND EASTHAM, W. N.: Acute liver necrosis following overdose of paracetamol. Br. Med. J. 2: 497-499, 1966.
    • (1966) Br. Med. J. , vol.2 , pp. 497-499
    • Davidson, D.G.D.1    Eastham, W.N.2
  • 19
    • 0024341761 scopus 로고
    • Reversible and irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI)
    • ESTERLINE, R. L., RAY, S. D. AND JI, S.: Reversible and irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). Biochem. Pharmacol. 38: 2387-2390, 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 2387-2390
    • Esterline, R.L.1    Ray, S.D.2    Ji, S.3
  • 22
    • 0028099926 scopus 로고
    • An electron microscopic study of apoptosis induced by cycloheximide in rat liver
    • FAA, G., LEDDA-COLUMBANO, G. M., AMBU, R., CONGIU, T., CONI, P., RIVA, A. AND COLUMBANO, A.: An electron microscopic study of apoptosis induced by cycloheximide in rat liver. Liver 14: 270-278, 1994.
    • (1994) Liver , vol.14 , pp. 270-278
    • Faa, G.1    Ledda-Columbano, G.M.2    Ambu, R.3    Congiu, T.4    Coni, P.5    Riva, A.6    Columbano, A.7
  • 23
    • 0025572583 scopus 로고
    • Oxygen toxicity: Unique cytoprotective properties of alpha tocopheryl succinate in hepatocytes
    • FARISS, M. W.: Oxygen toxicity: Unique cytoprotective properties of alpha tocopheryl succinate in hepatocytes. Free Rad. Biol. Med. 9: 333-343, 1990.
    • (1990) Free Rad. Biol. Med. , vol.9 , pp. 333-343
    • Fariss, M.W.1
  • 24
    • 0027435495 scopus 로고
    • Protection against carbontetrachloride-induced hepatotoxicity by pretreating rats with the hemisuccinate esters of tocopherol and cholesterol
    • FARISS, M. W., BRYSON, K. F., HYLTON, E. E., LIPPMAN, H. R., STUBIN, C. H. AND ZHAO, X-G.: Protection against carbontetrachloride-induced hepatotoxicity by pretreating rats with the hemisuccinate esters of tocopherol and cholesterol. Env. Health Pers. 101: 528-536, 1993.
    • (1993) Env. Health Pers. , vol.101 , pp. 528-536
    • Fariss, M.W.1    Bryson, K.F.2    Hylton, E.E.3    Lippman, H.R.4    Stubin, C.H.5    Zhao, X.-G.6
  • 25
    • 0027990215 scopus 로고
    • Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death
    • FERNANDES, R. S. AND COTTER, T. G.: Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death. Biochem. Pharmacol. 48: 675-681, 1994.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 675-681
    • Fernandes, R.S.1    Cotter, T.G.2
  • 26
    • 0026689242 scopus 로고
    • Apoptosis: A different type of cell death
    • GERSCHENSON, L. E. AND ROTELLO, R. J.: Apoptosis: A different type of cell death. FASEB J. 6: 2450-2455, 1992.
    • (1992) FASEB J. , vol.6 , pp. 2450-2455
    • Gerschenson, L.E.1    Rotello, R.J.2
  • 27
    • 0021864145 scopus 로고
    • The effectiveness of antioxidants in reducing paracetamol-induced damage subsequent to paracetamol activation
    • HARMAN, A. W.: The effectiveness of antioxidants in reducing paracetamol-induced damage subsequent to paracetamol activation. Res. Commu. Chem. Pathol. Pharmacol. 49: 215-228, 1985.
    • (1985) Res. Commu. Chem. Pathol. Pharmacol. , vol.49 , pp. 215-228
    • Harman, A.W.1
  • 28
    • 0026582702 scopus 로고
    • Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
    • HENGARTNER, M. O., ELLIS, R. E. AND HORVITZ, H. R.: Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 356: 494-499, 1992.
    • (1992) Nature , vol.356 , pp. 494-499
    • Hengartner, M.O.1    Ellis, R.E.2    Horvitz, H.R.3
  • 29
    • 0028288277 scopus 로고
    • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
    • HENGARTNER, M. O. AND HORVITZ, H. R.: C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76: 665-676, 1994.
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 30
    • 0020606974 scopus 로고
    • Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice
    • HINSON, J. A., MAYS, J. B. AND CAMERON, A. M.: Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice. Biochem. Pharmacol. 32: 1979-1988, 1983.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 1979-1988
    • Hinson, J.A.1    Mays, J.B.2    Cameron, A.M.3
  • 31
    • 0020328147 scopus 로고
    • Cimitidine protects against acetaminophen toxicity
    • JACKSON, J. E.: Cimitidine protects against acetaminophen toxicity. Life Sci. 31: 31-35, 1982.
    • (1982) Life Sci. , vol.31 , pp. 31-35
    • Jackson, J.E.1
  • 32
    • 0025673837 scopus 로고
    • Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: The protective effect of allopurinol
    • JAESCHKE, H.: Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: The protective effect of allopurinol. J. Pharmacol. Exp. Ther. 265: 935-941, 1990.
    • (1990) J. Pharmacol. Exp. Ther. , vol.265 , pp. 935-941
    • Jaeschke, H.1
  • 34
    • 0028046589 scopus 로고
    • Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells
    • JARVIS, W. D., FORNARI, F. A., BROWNING, J. L., GEWIRTZ, D. A., KOLESNICK, R. N. AND GRANT, S.: Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. J. Biol. Chem. 269: 31685-31692, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31685-31692
    • Jarvis, W.D.1    Fornari, F.A.2    Browning, J.L.3    Gewirtz, D.A.4    Kolesnick, R.N.5    Grant, S.6
  • 35
    • 0019992090 scopus 로고
    • Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium homeostasis
    • JEWELL, S. A., BELLOMO, G., THOR, H., ORRENIUS, S. AND SMITH, M. T.: Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium homeostasis. Science 217: 1257-1259, 1982.
    • (1982) Science , vol.217 , pp. 1257-1259
    • Jewell, S.A.1    Bellomo, G.2    Thor, H.3    Orrenius, S.4    Smith, M.T.5
  • 36
    • 0022438444 scopus 로고
    • Intracellular dissipative structures as the ultimate targets of cytotoxicity
    • JI, S., RAY, S. D. AND ESTERLINE, R. L.: Intracellular dissipative structures as the ultimate targets of cytotoxicity. Adv. Exp. Biol. Med. 197: 871-889, 1986.
    • (1986) Adv. Exp. Biol. Med. , vol.197 , pp. 871-889
    • Ji, S.1    Ray, S.D.2    Esterline, R.L.3
  • 37
    • 0024543754 scopus 로고
    • Calcium-activated DNA fragmentation in rat liver nuclei
    • JONES, D. P., MCCONKEY, D. J., NICOTERA, P. AND ORRENIUS, S.: Calcium-activated DNA fragmentation in rat liver nuclei. J. Biol. Chem. 264: 6398-6403, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 6398-6403
    • Jones, D.P.1    Mcconkey, D.J.2    Nicotera, P.3    Orrenius, S.4
  • 39
    • 0015117787 scopus 로고
    • Shrinkage necrosis: A distinct mode of cellular death
    • KERR, J. F. R.: Shrinkage necrosis: A distinct mode of cellular death. J. Pathol. 105: 13-22, 1971.
    • (1971) J. Pathol. , vol.105 , pp. 13-22
    • Kerr, J.F.R.1
  • 40
    • 0013908563 scopus 로고
    • The ultrastructure of acidophillic "councilman-like" bodies in the liver
    • KLION, F. M. AND SCHAFFNER, F.: The ultrastructure of acidophillic "councilman-like" bodies in the liver. Am. J. Pathol. 48: 755-765, 1966.
    • (1966) Am. J. Pathol. , vol.48 , pp. 755-765
    • Klion, F.M.1    Schaffner, F.2
  • 41
    • 0024537229 scopus 로고
    • Effects of cholesteryl esters on the accessibility of LH/hCG receptors membrane lipid fluidity in rat testes
    • KOLENA, J. AND KASAL, A.: Effects of cholesteryl esters on the accessibility of LH/hCG receptors membrane lipid fluidity in rat testes. Biochem. Biophys. Acta 979: 279-286, 1989.
    • (1989) Biochem. Biophys. Acta , vol.979 , pp. 279-286
    • Kolena, J.1    Kasal, A.2
  • 42
    • 0019507149 scopus 로고
    • Studies on the effects of L-ascorbic acid on acetaminophen-induced hepatotoxicity. 1. Inhibition of covalent binding of acetaminophen metabolites to hepatic microsomes in vitro
    • LAKE, B. G., ROSALYN, H. A., PHILLIPS, J. C. AND GANGOLLI, S. D.: Studies on the effects of L-ascorbic acid on acetaminophen-induced hepatotoxicity. 1. Inhibition of covalent binding of acetaminophen metabolites to hepatic microsomes in vitro. Toxicol. Appl. Pharmacol. 60: 229-240, 1981.
    • (1981) Toxicol. Appl. Pharmacol. , vol.60 , pp. 229-240
    • Lake, B.G.1    Rosalyn, H.A.2    Phillips, J.C.3    Gangolli, S.D.4
  • 43
    • 0021988229 scopus 로고
    • Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behaviour of phospholipid membranes
    • LAI, M. Z., DUZGUNES, N. AND SZOKA, F. C.: Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behaviour of phospholipid membranes. Biochemistry 24: 1646-1653, 1985.
    • (1985) Biochemistry , vol.24 , pp. 1646-1653
    • Lai, M.Z.1    Duzgunes, N.2    Szoka, F.C.3
  • 44
    • 0028948724 scopus 로고
    • Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen
    • LASKIN, D. L., GARDNER, C. E., PRICE, V. F. AND JOLLOW, D. J.: Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology 21: 1045-1050, 1995.
    • (1995) Hepatology , vol.21 , pp. 1045-1050
    • Laskin, D.L.1    Gardner, C.E.2    Price, V.F.3    Jollow, D.J.4
  • 45
    • 0026675719 scopus 로고
    • Altered microviscosity at brain membrane surface induces distinct and reversible inhibition of opioid receptor binding
    • LAZAR, D. F. AND MEDZIHRADSKY, F.: Altered microviscosity at brain membrane surface induces distinct and reversible inhibition of opioid receptor binding. J. Neurochem. 59: 1233-1240, 1992.
    • (1992) J. Neurochem. , vol.59 , pp. 1233-1240
    • Lazar, D.F.1    Medzihradsky, F.2
  • 46
    • 0029328321 scopus 로고
    • A toxicologic pathologist's view of apoptosis or I used to call it necrosis, but now I'am singing the apoptosis blues
    • LEVIN, S.: A toxicologic pathologist's view of apoptosis or I used to call it necrosis, but now I'am singing the apoptosis blues. Toxic. Pathol. 23: 533-539, 1995.
    • (1995) Toxic. Pathol. , vol.23 , pp. 533-539
    • Levin, S.1
  • 47
    • 0022586722 scopus 로고
    • Li-Na counter transport and Li leak in erythrocytes are differentially affected by membrane enrichment with choleateryl hemisuccinate
    • LEVY, R., HEVRONI, D., CABANTCHIK, Z. I. AND LIVNE, A.: Li-Na counter transport and Li leak in erythrocytes are differentially affected by membrane enrichment with choleateryl hemisuccinate. Biochem. Biophya. Acta 854: 325-328, 1986.
    • (1986) Biochem. Biophya. Acta , vol.854 , pp. 325-328
    • Levy, R.1    Hevroni, D.2    Cabantchik, Z.I.3    Livne, A.4
  • 48
    • 0028151033 scopus 로고
    • Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes
    • LI, Q-J., BESSEMS, J. G. M., COMMANDEUR, J. N. M., ADAMS, B. AND VERMEULEN, N. P. E.: Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes. Biochem. Pharmacol. 48: 1631-1640, 1994.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1631-1640
    • Li, Q.-J.1    Bessems, J.G.M.2    Commandeur, J.N.M.3    Adams, B.4    Vermeulen, N.P.E.5
  • 49
    • 0023940527 scopus 로고
    • Metabolic effects of ethanol and its interaction with other drugs, hepatotoxic agents, vitamins, and carcinogens: A 1988 update
    • LIEBER, C. S.: Metabolic effects of ethanol and its interaction with other drugs, hepatotoxic agents, vitamins, and carcinogens: A 1988 update. Semin. Liver Dis. 8: 47-68, 1988.
    • (1988) Semin. Liver Dis. , vol.8 , pp. 47-68
    • Lieber, C.S.1
  • 50
    • 0027847679 scopus 로고
    • Protective effects of oleanolic acid on acetaminophen-induced hepatotoxicity in mice
    • LIU, J., LIU, Y., MADHU, C. AND KLAASSEN, C. D.: Protective effects of oleanolic acid on acetaminophen-induced hepatotoxicity in mice. J. Pharmacol. Exp. Ther. 22: 1607-1613, 1993.
    • (1993) J. Pharmacol. Exp. Ther. , vol.22 , pp. 1607-1613
    • Liu, J.1    Liu, Y.2    Madhu, C.3    Klaassen, C.D.4
  • 51
    • 55549122117 scopus 로고
    • The effects of 10 triterpenoid compounds on experimental liver injury in mice
    • LIU, J., LIU, Y., MAO, Q. AND KLAASSEN, C. D.: The effects of 10 triterpenoid compounds on experimental liver injury in mice. Fund. Appl. Toxicol. 22: 34-40, 1994a.
    • (1994) Fund. Appl. Toxicol. , vol.22 , pp. 34-40
    • Liu, J.1    Liu, Y.2    Mao, Q.3    Klaassen, C.D.4
  • 52
    • 0029111799 scopus 로고
    • Oxidative stress by acute acetaminophen administration in mouse liver
    • LORES-ARNAIZ, S., LLESUY, S., CURTIN, J. C. AND BOVERIS, A.: Oxidative stress by acute acetaminophen administration in mouse liver. Free Rad. Biol. Med. 19: 303-310, 1995.
    • (1995) Free Rad. Biol. Med. , vol.19 , pp. 303-310
    • Lores-Arnaiz, S.1    Llesuy, S.2    Curtin, J.C.3    Boveris, A.4
  • 53
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis: An overview of cell death
    • MAJNO, G. AND JORIS, I.: Apoptosis, oncosis, and necrosis: An overview of cell death. Am. J. Pathol. 146: 3-15, 1995.
    • (1995) Am. J. Pathol. , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 57
    • 0026443972 scopus 로고
    • Silymarin protects against paracetamol-induced lipid peroxidation and liver damage
    • MURIEL, P., GARCIAPINA, T., PEREZ-ALVAREZ, V. AND MOURELLE, M.: Silymarin protects against paracetamol-induced lipid peroxidation and liver damage. J. Appl. Toxicol. 12: 439-442, 1992.
    • (1992) J. Appl. Toxicol. , vol.12 , pp. 439-442
    • Muriel, P.1    Garciapina, T.2    Perez-Alvarez, V.3    Mourelle, M.4
  • 58
    • 0025694879 scopus 로고
    • Molecular mechanisms of the hepatotoxicity caused by acetaminophen
    • NELSON, S. D.: Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Semin. Liver Dis. 10: 267-278, 1990.
    • (1990) Semin. Liver Dis. , vol.10 , pp. 267-278
    • Nelson, S.D.1
  • 59
    • 0029053262 scopus 로고
    • Mechanisms of the formation and disposition of reactive metabolites that can cause acute liver injury
    • NELSON, S. D.: Mechanisms of the formation and disposition of reactive metabolites that can cause acute liver injury. Drug. Metab. Rev. 27: 147-177, 1995.
    • (1995) Drug. Metab. Rev. , vol.27 , pp. 147-177
    • Nelson, S.D.1
  • 61
    • 0027458695 scopus 로고
    • Characterization of endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)
    • PEITSCH, M. C., POLZAR, B., STEPHAN, H., CROMPTON, T., ROBSON, M., MANNHERZ, H. G. AND TSCHOPP, J.: Characterization of endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J. 12: 371-385, 1993.
    • (1993) EMBO J. , vol.12 , pp. 371-385
    • Peitsch, M.C.1    Polzar, B.2    Stephan, H.3    Crompton, T.4    Robson, M.5    Mannherz, H.G.6    Tschopp, J.7
  • 62
    • 0024401864 scopus 로고
    • Apoptosis-The mechanisms of cell death in dimethylnitrosamine-induced hepatotoxicity
    • PRICHARD, D. J. AND BUTLER, W. H.: Apoptosis-The mechanisms of cell death in dimethylnitrosamine-induced hepatotoxicity. J. Pathol. 158: 253-260, 1989.
    • (1989) J. Pathol. , vol.158 , pp. 253-260
    • Prichard, D.J.1    Butler, W.H.2
  • 63
    • 0024454385 scopus 로고
    • In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria
    • RAMSAY, R. P., RASHED, M. S. AND NELSON, S. D.: In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria. Arch. Biochem. Biophys. 273: 449-457, 1989.
    • (1989) Arch. Biochem. Biophys. , vol.273 , pp. 449-457
    • Ramsay, R.P.1    Rashed, M.S.2    Nelson, S.D.3
  • 64
    • 0008925762 scopus 로고
    • Inhibition of acetaminophen-induced liver injury by glucose, mannitol or ethanol: Evidence that glucose is an endogenous free radical scavenger
    • RAY, S. D., ESTERLINE, R. L. AND JI, S.: Inhibition of acetaminophen-induced liver injury by glucose, mannitol or ethanol: Evidence that glucose is an endogenous free radical scavenger. Fed. Proc. 45: 702, 1986.
    • (1986) Fed. Proc. , vol.45 , pp. 702
    • Ray, S.D.1    Esterline, R.L.2    Ji, S.3
  • 65
    • 12644259492 scopus 로고
    • Reversible and irreversible components of acetaminophen-induced "slow inhibition of hepatic respiration" in livers from rats pretreated with ethanol
    • RAY, S. D., ESTERLINE, R. L. AND JI, S.: Reversible and irreversible components of acetaminophen-induced "slow inhibition of hepatic respiration" in livers from rats pretreated with ethanol. FASEB J. 2: 802, 1988.
    • (1988) FASEB J. , vol.2 , pp. 802
    • Ray, S.D.1    Esterline, R.L.2    Ji, S.3
  • 66
    • 0025197810 scopus 로고
    • Potentiation of CC14 and CHC13 hepatotoxicity and lethality by various alcohols
    • RAY, S. D. AND MEHENDALE, H. M.: Potentiation of CC14 and CHC13 hepatotoxicity and lethality by various alcohols. Fund. Appl. Toxicol. 15: 429-440, 1990.
    • (1990) Fund. Appl. Toxicol. , vol.15 , pp. 429-440
    • Ray, S.D.1    Mehendale, H.M.2
  • 67
    • 0008930509 scopus 로고
    • Perplexed mouse hepatocytes in vivo show signs of both apoptosis and necrosis under the influence of acetaminophen and dimethylnitrosamine
    • New Hampshire, July
    • RAY, S. D. AND RAJE, R. R.: Perplexed mouse hepatocytes in vivo show signs of both apoptosis and necrosis under the influence of acetaminophen and dimethylnitrosamine. Gordon Research Conference on "Clinical and Experimental Cancer Chemotherapy," New Hampshire, July 1994.
    • (1994) Gordon Research Conference on "Clinical and Experimental Cancer Chemotherapy,"
    • Ray, S.D.1    Raje, R.R.2
  • 68
    • 0344928983 scopus 로고
    • Damage to the nucleus and acute cell death produced by alkylating hepatotoxins
    • ed. by S. Ji, Rutgers University Press, New Brunswick, NJ
    • RAY, S. D. AND CORCORAN, G. B.: Damage to the nucleus and acute cell death produced by alkylating hepatotoxins. In Molecular Theories of Cell Life and Death," ed. by S. Ji, pp. 338-400, Rutgers University Press, New Brunswick, NJ, 1991.
    • (1991) Molecular Theories of Cell Life and Death , pp. 338-400
    • Ray, S.D.1    Corcoran, G.B.2
  • 71
    • 12644256615 scopus 로고
    • Acetaminophen-induced DNA fragmentation and cell death studied in vitro in cultured mouse hepatocytes
    • RAY, S. D., KAMENDULIS, L., SHEN, W. AND CORCORAN, G. B.: Acetaminophen-induced DNA fragmentation and cell death studied in vitro in cultured mouse hepatocytes. Toxicologist 11: 67, 1991b.
    • (1991) Toxicologist , vol.11 , pp. 67
    • Ray, S.D.1    Kamendulis, L.2    Shen, W.3    Corcoran, G.B.4
  • 74
    • 12644277363 scopus 로고
    • Acetaminophen-induced apoptosis and necrosis: In vivo protection by cholesteryl hemisuccinate pretreatment
    • RAY, S. D., MUMAW, V. R., LIPPMAN, R., FARISS, M. W.: Acetaminophen-induced apoptosis and necrosis: In vivo protection by cholesteryl hemisuccinate pretreatment. Toxicologist 14: 187, 1994.
    • (1994) Toxicologist , vol.14 , pp. 187
    • Ray, S.D.1    Mumaw, V.R.2    Lippman, R.3    Fariss, M.W.4
  • 75
    • 0028243895 scopus 로고
    • Role of cellular energy status in tocopheryl hemisuccinate cytoprotection against ethylmethanesulfonate-induced toxicity
    • RAY, S. D. AND FARISS, M. W.: Role of cellular energy status in tocopheryl hemisuccinate cytoprotection against ethylmethanesulfonate-induced toxicity. Arch. Biochem. Biophys. 311: 180-190, 1994.
    • (1994) Arch. Biochem. Biophys. , vol.311 , pp. 180-190
    • Ray, S.D.1    Fariss, M.W.2
  • 76
    • 74049090782 scopus 로고    scopus 로고
    • 3-Aminobenzamide, a modulator of apoptosis and necrosis induced by acetaminophen does not interfere with P450IIE1 activity in vivo or in vitro
    • RAY, S. D., MUNOZ, R. AND KRANER, J. C.: 3-Aminobenzamide, a modulator of apoptosis and necrosis induced by acetaminophen does not interfere with P450IIE1 activity in vivo or in vitro. Toxicologist 30: 71, 1996.
    • (1996) Toxicologist , vol.30 , pp. 71
    • Ray, S.D.1    Munoz, R.2    Kraner, J.C.3
  • 77
    • 0021825310 scopus 로고
    • Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil
    • RENTON, K. W.: Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil. Biochem. Pharmacol. 14: 2549-2553, 1985.
    • (1985) Biochem. Pharmacol. , vol.14 , pp. 2549-2553
    • Renton, K.W.1
  • 78
    • 0025981219 scopus 로고
    • Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity
    • ROBERTS, D. W., BUCCI, T. J., WAYNE BENSON, R., WARBRITTON, A. R., MCRAE, T. A., PUMFORD, N. R. AND HINSON, J. A.: Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity. Am. J. Pathol. 138: 359-371, 1991.
    • (1991) Am. J. Pathol. , vol.138 , pp. 359-371
    • Roberts, D.W.1    Bucci, T.J.2    Wayne Benson, R.3    Warbritton, A.R.4    Mcrae, T.A.5    Pumford, N.R.6    Hinson, J.A.7
  • 79
    • 0022617943 scopus 로고
    • The mechanism of cobalt chloride-induced protection against acetaminophen hepatotoxicity
    • ROBERTS, S. A., PRICE, V. F. AND JOLLOW, D. J.: The mechanism of cobalt chloride-induced protection against acetaminophen hepatotoxicity. Drug. Metab. Dispos. 14: 25-33, 1986.
    • (1986) Drug. Metab. Dispos. , vol.14 , pp. 25-33
    • Roberts, S.A.1    Price, V.F.2    Jollow, D.J.3
  • 80
    • 0023888005 scopus 로고
    • Inhibition of acetaminophen hepatotoxicity by chloropromazine in fed and fasted mice
    • SAVILLE, J. G., DAVIDSON, C. P., D'ANDREA, G. H., BORN, C. K. AND HAMRICK, M. E.: Inhibition of acetaminophen hepatotoxicity by chloropromazine in fed and fasted mice. Biochem. Pharmacol. 37: 2467-2471, 1988.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2467-2471
    • Saville, J.G.1    Davidson, C.P.2    D'Andrea, G.H.3    Born, C.K.4    Hamrick, M.E.5
  • 81
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • SCHWARTZMAN, R. A. AND CIDLOWSKI, J. A.: Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocrinol. Rev. 14: 133-151, 1993.
    • (1993) Endocrinol. Rev. , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 83
    • 0024262737 scopus 로고
    • Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose
    • SMILKSTEIN, M. J., KNAPP, G. L., KULIG, K. W. AND RUMACK, B. H.: Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. N. Engl. J. Med. 319: 1557-1562, 1988.
    • (1988) N. Engl. J. Med. , vol.319 , pp. 1557-1562
    • Smilkstein, M.J.1    Knapp, G.L.2    Kulig, K.W.3    Rumack, B.H.4
  • 84
    • 0026619940 scopus 로고
    • Cholesterol and mevalonic acid modulation in cell metabolism and multiplication
    • SOMA, M. R., CORSINI, A. AND PAOLETTI, R.: Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol. Lett. 64/65: 1-15, 1992.
    • (1992) Toxicol. Lett. , vol.64-65 , pp. 1-15
    • Soma, M.R.1    Corsini, A.2    Paoletti, R.3
  • 85
    • 0028156903 scopus 로고
    • Separate metabolic pathways leading to DNA fragmentation and apoptotic chromatin condensation
    • SUN, D. Y., JIANG, S., ZHENG, L., OJCIUS, D. M. AND YOUNG, J. D.: Separate metabolic pathways leading to DNA fragmentation and apoptotic chromatin condensation. J. Exp. Med. 179: 559-568, 1994.
    • (1994) J. Exp. Med. , vol.179 , pp. 559-568
    • Sun, D.Y.1    Jiang, S.2    Zheng, L.3    Ojcius, D.M.4    Young, J.D.5
  • 86
    • 74049161898 scopus 로고    scopus 로고
    • Cadmium and chromium induced oxidative stress and programmed cell death in cultured J774A.1 macrophage cells
    • TRAN, M. X., STOHS, S. J., NEWTON, S., BAGCHI, D., BAGCHI, M., TANG, L. AND RAY, S. D.: Cadmium and chromium induced oxidative stress and programmed cell death in cultured J774A.1 macrophage cells. Toxicologist 30: 167, 1996.
    • (1996) Toxicologist , vol.30 , pp. 167
    • Tran, M.X.1    Stohs, S.J.2    Newton, S.3    Bagchi, D.4    Bagchi, M.5    Tang, L.6    Ray, S.D.7
  • 87
    • 0026645504 scopus 로고
    • Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes
    • UCKER, D. S., OBERMILLER, P. S., ECKHART, W., APGAR, J. P., BERGER, N. A. AND MEYERS, J.: Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mol. Cell. Biol. 12: 3060-3070, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3060-3070
    • Ucker, D.S.1    Obermiller, P.S.2    Eckhart, W.3    Apgar, J.P.4    Berger, N.A.5    Meyers, J.6
  • 88
    • 0014945083 scopus 로고
    • Properties of rapidly labelled deoxyribonucleic acid fragments isolated from the cytoplasm of primary cultures of embryonic mouse liver cells
    • WILLIAMSON, R.: Properties of rapidly labelled deoxyribonucleic acid fragments isolated from the cytoplasm of primary cultures of embryonic mouse liver cells. J. Mol. Biol. 51: 157-168, 1970.
    • (1970) J. Mol. Biol. , vol.51 , pp. 157-168
    • Williamson, R.1
  • 89
    • 0020379860 scopus 로고
    • Endogenous nuclease. Properties and effects on transcribed genes in chromatin
    • VANDERBILT, J. N., BLOOM, K. S. AND ANDERSON, J. N.: Endogenous nuclease. Properties and effects on transcribed genes in chromatin. J. Biol. Chem. 257: 13009-13107, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13009-13107
    • Vanderbilt, J.N.1    Bloom, K.S.2    Anderson, J.N.3
  • 90
    • 78651031427 scopus 로고
    • Serum glutamic pyruvic transaminase in cardiac and hepatic disease
    • WROBLEWSKI, F. AND LADUE, J.: Serum glutamic pyruvic transaminase in cardiac and hepatic disease. Proc. Soc. Exp. Biol. Med. 91: 569-571, 1956.
    • (1956) Proc. Soc. Exp. Biol. Med. , vol.91 , pp. 569-571
    • Wroblewski, F.1    Ladue, J.2
  • 91
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • WYLLIE, A. H.: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556, 1980.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 92
    • 0000321478 scopus 로고
    • Abrogation of acetaminophen-induced hepatotoxicity by 3-aminobenzamide, a DNA repair modulator
    • YAHYA, S. M., RAY, S. D. AND RAJE, R. R.: Abrogation of acetaminophen-induced hepatotoxicity by 3-aminobenzamide, a DNA repair modulator. Fund. Appl. Toxicol. (The Toxicologist) 15: 133, 1995.
    • (1995) Fund. Appl. Toxicol. (The Toxicologist) , vol.15 , pp. 133
    • Yahya, S.M.1    Ray, S.D.2    Raje, R.R.3
  • 93
    • 0025026430 scopus 로고
    • Antagonism of acetaminophen-induced hepatocellular destruction by trifluoperazine in mice
    • YAMAMOTO, H. -A.: Antagonism of acetaminophen-induced hepatocellular destruction by trifluoperazine in mice. Pharmacol. Toxicol. 67: 115-119, 1990.
    • (1990) Pharmacol. Toxicol. , vol.67 , pp. 115-119
    • Yamamoto, H.A.1
  • 94
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • YONISH-ROUCH, E., RESNITZKY, D., LOTEM, J., SACHS, L., KIMCHI, A. AND OREN, M.: Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-347, 1991.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouch, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 95
    • 0027318190 scopus 로고
    • Bcl-2 inhibits death of central neural cells induced by multiple agents
    • ZHONG, L. T., SARAFIAN, T., KANE, D. J.: Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. U.S.A. 90: 4533-4541, 1993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 4533-4541
    • Zhong, L.T.1    Sarafian, T.2    Kane, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.