Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

Hepatology

Volumn 30, Issue 1, 1999, Pages 186-195

  Michael, Sherryll L ^a   Pumford, Neil R ^a   Mayeux, Philip R ^a   Niesman, Michael R ^a,b   Hinson, Jack A ^a,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b AGOURON PHARMACEUTICALS INC   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; DEXTRAN SULFATE; GADOLINIUM CHLORIDE; NITRIC OXIDE; PARACETAMOL; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TYROSINE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COVALENT BOND; CYTOLYSIS; IMMUNOHISTOCHEMISTRY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KUPFFER CELL; LIVER CELL; LIVER HISTOLOGY; LIVER HOMOGENATE; LIVER NECROSIS; LIVER TOXICITY; MACROPHAGE ACTIVATION; MALE; METABOLIC ACTIVATION; MOUSE; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WESTERN BLOTTING;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ASPARTATE AMINOTRANSFERASES; DEXTRAN SULFATE; GADOLINIUM; KUPFFER CELLS; LIVER; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED STRAINS; NECROSIS; NITRATES; NITRIC OXIDE; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 0033000310     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510300104     Document Type: Article

References (22)

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