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Volumn 3, Issue 1, 2003, Pages 51-62

Hepatic T cells and liver tolerance

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR1; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0037270978     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri981     Document Type: Review
Times cited : (604)

References (169)
  • 2
    • 0030994929 scopus 로고    scopus 로고
    • Enterotropic mouse hepatitis virus
    • Homberger, F. R. Enterotropic mouse hepatitis virus. Lab. Anim. 31, 97-115 (1997).
    • (1997) Lab. Anim. , vol.31 , pp. 97-115
    • Homberger, F.R.1
  • 3
    • 0028803426 scopus 로고
    • The protective role of cytotoxic T cells and interferon against coronavirus invasion of the brain
    • Lavi, E. & Wang, Q. The protective role of cytotoxic T cells and interferon against coronavirus invasion of the brain. Adv. Exp. Med. Biol. 380, 145-149 (1995).
    • (1995) Adv. Exp. Med. Biol. , vol.380 , pp. 145-149
    • Lavi, E.1    Wang, Q.2
  • 4
    • 0028909257 scopus 로고
    • Development of immunity to malana may not be an entirely active process
    • Good, M. F. Development of immunity to malana may not be an entirely active process. Parasite Immunol. 17, 55-59 (1995).
    • (1995) Parasite Immunol. , vol.17 , pp. 55-59
    • Good, M.F.1
  • 5
    • 0029838758 scopus 로고    scopus 로고
    • The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response
    • Rehermann, B., Ferrari, C., Pasquinelli, C. & Chisari, F. V. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nature Med. 2, 1104-1108 (1996).
    • (1996) Nature Med. , vol.2 , pp. 1104-1108
    • Rehermann, B.1    Ferrari, C.2    Pasquinelli, C.3    Chisari, F.V.4
  • 7
    • 0014661390 scopus 로고
    • Induction of immunological tolerance by porcine liver allografts
    • Calne, R. Y. et al. Induction of immunological tolerance by porcine liver allografts. Nature 223, 472-476 (1969).
    • (1969) Nature , vol.223 , pp. 472-476
    • Calne, R.Y.1
  • 8
    • 0026322151 scopus 로고
    • A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
    • van der Bruggen, P. et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254, 1643-1647 (1991).
    • (1991) Science , vol.254 , pp. 1643-1647
    • Van der Bruggen, P.1
  • 11
    • 0026721306 scopus 로고
    • Evidence for Kupffer-cell migration along liver sinusoids, from high-resolution in vivo microscopy
    • MacPhee, P. J., Schmidt, E. E. & Groom, A. C. Evidence for Kupffer-cell migration along liver sinusoids, from high-resolution in vivo microscopy. Am. J. Physiol. 263, G17-G23 (1992).
    • (1992) Am. J. Physiol. , vol.263
    • MacPhee, P.J.1    Schmidt, E.E.2    Groom, A.C.3
  • 12
    • 0029956461 scopus 로고    scopus 로고
    • Apoptosis of neutrophils and their elimination by Kupffer cells in rat liver
    • Shi, J., Fujieda, H., Kokubo, Y. & Wake, K. Apoptosis of neutrophils and their elimination by Kupffer cells in rat liver. Hepatology 24, 1256-1263 (1996).
    • (1996) Hepatology , vol.24 , pp. 1256-1263
    • Shi, J.1    Fujieda, H.2    Kokubo, Y.3    Wake, K.4
  • 13
    • 0032872280 scopus 로고    scopus 로고
    • Modulation of cell-surface expression of liver carbohydrate receptors during in vivo induction of apoptosis with lead nitrate
    • Ruzittu, M., Carla, E. C., Montinari, M. R., Maietta, G. & Dini, L. Modulation of cell-surface expression of liver carbohydrate receptors during in vivo induction of apoptosis with lead nitrate. Cell Tissue Res. 298, 105-112 (1999).
    • (1999) Cell Tissue Res. , vol.298 , pp. 105-112
    • Ruzittu, M.1    Carla, E.C.2    Montinari, M.R.3    Maietta, G.4    Dini, L.5
  • 14
    • 0023933641 scopus 로고
    • Antimicrobial properties of Kupffer cells
    • Filice, G. A. Antimicrobial properties of Kupffer cells. Infect. Immun. 56, 1430-1435 (1988).
    • (1988) Infect. Immun. , vol.56 , pp. 1430-1435
    • Filice, G.A.1
  • 15
    • 0023254044 scopus 로고
    • Kupffer cells and their function
    • Wardle, E. N. Kupffer cells and their function. Liver 7, 63-75 (1987)
    • (1987) Liver , vol.7 , pp. 63-75
    • Wardle, E.N.1
  • 16
    • 0017349821 scopus 로고
    • Clearance of viable Calmette-Guerin bacillus by the in vitro isolated and perfused rat liver
    • Ruggiero, G. et al. Clearance of viable Calmette-Guerin bacillus by the in vitro isolated and perfused rat liver. Acta Hepatogastroenterol. (Stuttg.) 24, 102-105 (1977).
    • (1977) Acta Hepatogastroenterol. (Stuttg.) , vol.24 , pp. 102-105
    • Ruggiero, G.1
  • 17
    • 0018898831 scopus 로고
    • Antigen presentation by isolated guinea-pig Kupffer cells
    • Rogoff, T. M. & Lipsky, P. E. Antigen presentation by isolated guinea-pig Kupffer cells. J. Immunol. 124, 1740-1744 (1980).
    • (1980) J. Immunol. , vol.124 , pp. 1740-1744
    • Rogoff, T.M.1    Lipsky, P.E.2
  • 18
    • 0025316750 scopus 로고
    • + T-lymphocyte clone to Listeria monocytogenes
    • + T-lymphocyte clone to Listeria monocytogenes. Infect. Immun. 58, 2313-2319 (1990).
    • (1990) Infect. Immun. , vol.58 , pp. 2313-2319
    • Gregory, S.H.1    Wing, E.J.2
  • 19
    • 0027986808 scopus 로고
    • H1 lymphocyte depends on the inducibility of nitric oxide synthase by iFN-γ
    • H1 lymphocyte depends on the inducibility of nitric oxide synthase by iFN-γ. J. Immunol. 153, 5453-5464 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 5453-5464
    • Roland, C.R.1    Walp, L.2    Stack, R.M.3    Flye, M.W.4
  • 20
    • 0027959344 scopus 로고
    • Portal-vein adminstration of donor cells promotes peripheral allospecific hyporesponsiveness and graft tolerance
    • Yu, S., Nakafusa, Y. & Flye, M. W. Portal-vein adminstration of donor cells promotes peripheral allospecific hyporesponsiveness and graft tolerance. Surgery 116, 229-234 (1994).
    • (1994) Surgery , vol.116 , pp. 229-234
    • Yu, S.1    Nakafusa, Y.2    Flye, M.W.3
  • 21
    • 0027156240 scopus 로고
    • Lymphocyte suppression by Kupffer cells prevents portal venous tolerance induction: A study of macrophage function after intravenous gadolinium
    • Roland, C. R., Mangino, M. J., Duffy, B. F. & Flye, M. W. Lymphocyte suppression by Kupffer cells prevents portal venous tolerance induction: a study of macrophage function after intravenous gadolinium. Transplantation 55, 1151-1158 (1993).
    • (1993) Transplantation , vol.55 , pp. 1151-1158
    • Roland, C.R.1    Mangino, M.J.2    Duffy, B.F.3    Flye, M.W.4
  • 22
    • 0031937330 scopus 로고    scopus 로고
    • Resident human hepatic lymphocytes are phenotypically different from circulating lymphocytes
    • Norris, S. et al. Resident human hepatic lymphocytes are phenotypically different from circulating lymphocytes. J. Hepatol. 28, 84-90 (1998).
    • (1998) J. Hepatol. , vol.28 , pp. 84-90
    • Norris, S.1
  • 23
    • 0030297312 scopus 로고    scopus 로고
    • Strange brew: T cells in the liver
    • Crispe, I. N. & Mehal, W. Z. Strange brew: T cells in the liver Immunol. Today 17, 522-525 (1996).
    • (1996) Immunol. Today , vol.17 , pp. 522-525
    • Crispe, I.N.1    Mehal, W.Z.2
  • 24
    • 0029070664 scopus 로고
    • Characterization, quantification and localization of passenger T lymphocytes and NK cells in human liver before transplantation
    • Pruvot, F. R. et al. Characterization, quantification and localization of passenger T lymphocytes and NK cells in human liver before transplantation. Transpl. Int. 8, 273-279 (1995).
    • (1995) Transpl. Int. , vol.8 , pp. 273-279
    • Pruvot, F.R.1
  • 26
    • 0036191532 scopus 로고    scopus 로고
    • Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver
    • Klugewitz, K. et al Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver. Hepatology 35, 568-578 (2002).
    • (2002) Hepatology , vol.35 , pp. 568-578
    • Klugewitz, K.1
  • 27
    • 0036721727 scopus 로고    scopus 로고
    • + effector cells and suppression of IFN-γ-producing cells after intravenous protein immunization
    • + effector cells and suppression of IFN-γ -producing cells after intravenous protein immunization. J. Immunol. 169, 2407-2413 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 2407-2413
    • Klugewitz, K.1
  • 29
    • 0030060153 scopus 로고    scopus 로고
    • Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand
    • Renno, T., Hahne, M., Tschopp, J. & MacDonald, H. R. Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand. J. Exp. Med. 183, 431-437 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 431-437
    • Renno, T.1    Hahne, M.2    Tschopp, J.3    MacDonald, H.R.4
  • 31
    • 0023153714 scopus 로고
    • Large granular lymphocytes or 'pit cells' from rat liver: Isolation, ultrastructural characterization and natural killer activity
    • Bouwens, L., Remels, L., Baekeland, M., Van Bossuyt, H. & Wisse, E. Large granular lymphocytes or 'pit cells' from rat liver: isolation, ultrastructural characterization and natural killer activity. Eur. J. Immunol. 17, 37-42 (1987).
    • (1987) Eur. J. Immunol. , vol.17 , pp. 37-42
    • Bouwens, L.1    Remels, L.2    Baekeland, M.3    Van Bossuyt, H.4    Wisse, E.5
  • 32
    • 0022998745 scopus 로고
    • Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection
    • McIntyre, K. W. & Welsh, R. M. Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection. J. Exp. Med. 164, 1667-1681 (1986).
    • (1986) J. Exp. Med. , vol.164 , pp. 1667-1681
    • McIntyre, K.W.1    Welsh, R.M.2
  • 33
    • 0031201232 scopus 로고    scopus 로고
    • + T cells for concanavalin-A-induced hepatic injury in mice
    • + T cells for concanavalin-A-induced hepatic injury in mice. J. Immunol. 159, 1537-1542 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 1537-1542
    • Toyabe, S.1
  • 34
    • 0034659912 scopus 로고    scopus 로고
    • NK cells cause liver injury and facilitate the induction of T-cell-mediated immunity to a viral liver infection
    • Liu, Z. X., Govindarajan, S., Okamoto, S. & Dennert, G. NK cells cause liver injury and facilitate the induction of T-cell-mediated immunity to a viral liver infection. J. Immunol. 164, 6480-6486 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 6480-6486
    • Liu, Z.X.1    Govindarajan, S.2    Okamoto, S.3    Dennert, G.4
  • 35
    • 0031974018 scopus 로고    scopus 로고
    • Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK-cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways
    • Salazar-Mather, T. P., Orange, J. S. & Biron, C. A. Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK-cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways. J. Exp. Med. 187, 1-14 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1-14
    • Salazar-Mather, T.P.1    Orange, J.S.2    Biron, C.A.3
  • 36
    • 17944378160 scopus 로고    scopus 로고
    • Time-course profile and cell-type-specific production of monokine induced by interferon-γ in concanavalin-A-induced hepatic injury in mice: Comparative study with interferon-inducible protein-10
    • Itoh, Y. et al. Time-course profile and cell-type-specific production of monokine induced by interferon-γ in concanavalin-A-induced hepatic injury in mice: comparative study with interferon-inducible protein-10. Scand. J. Gastroenterol. 36, 1344-1351 (2001).
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 1344-1351
    • Itoh, Y.1
  • 37
    • 0027305324 scopus 로고
    • Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression
    • Watanabe, H. et al. Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression. Cell. Immunol. 149, 331-342 (1993).
    • (1993) Cell. Immunol. , vol.149 , pp. 331-342
    • Watanabe, H.1
  • 38
    • 0036533422 scopus 로고    scopus 로고
    • Development and selection of NKT cells
    • MacDonald, H. R. Development and selection of NKT cells. Curr. Opin. Immunol. 14, 250-254 (2002).
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 250-254
    • MacDonald, H.R.1
  • 39
    • 0031240993 scopus 로고    scopus 로고
    • Vα14 NKT cells - A novel lymphoid cell lineage
    • inside front cover
    • MacDonald, H. R. Vα14 NKT cells - a novel lymphoid cell lineage. Jpn J. Cancer Res. 88, inside front cover (1997).
    • (1997) Jpn. J. Cancer Res. , vol.88
    • MacDonald, H.R.1
  • 40
    • 0033152796 scopus 로고    scopus 로고
    • Tissue-specific segregation of CD1d-dependent and CD1d-independent NKT cells
    • Eberl, G. et al. Tissue-specific segregation of CD1d-dependent and CD1d-independent NKT cells. J. Immunol. 162, 6410-6419 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 6410-6419
    • Eberl, G.1
  • 41
    • 0036227740 scopus 로고    scopus 로고
    • Activation of a nonclassical NKT-cell subset in a transgenic mouse model of hepatitis B virus infection
    • Baron, J. L. et al. Activation of a nonclassical NKT-cell subset in a transgenic mouse model of hepatitis B virus infection. Immunity 16, 583-594 (2002).
    • (2002) Immunity , vol.16 , pp. 583-594
    • Baron, J.L.1
  • 43
    • 0029112247 scopus 로고
    • Evidence for extrathymic generation of intermediate T-cell receptor cells in the liver revealed in thymectomized, irradiated mice subjected to bone-marrow transplantation
    • Sato, K. et al. Evidence for extrathymic generation of intermediate T-cell receptor cells in the liver revealed in thymectomized, irradiated mice subjected to bone-marrow transplantation. J. Exp. Med. 182, 759-767 (1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 759-767
    • Sato, K.1
  • 45
  • 47
    • 0037097505 scopus 로고    scopus 로고
    • Cutting edge: Vα14-Jα281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice
    • Mars, L. T. et al. Cutting edge: Vα14-Jα281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice. J. Immunol. 168, 6007-6011 (2002).
    • (2002) J. Immunol. , vol.168 , pp. 6007-6011
    • Mars, L.T.1
  • 48
    • 0035869449 scopus 로고    scopus 로고
    • H 2 shift circumscribed regionally to the islets and functionally to islet autoantigen
    • H2 shift circumscribed regionally to the islets and functionally to islet autoantigen. J. Immunol. 166, 3749-3756 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 3749-3756
    • Laloux, V.1    Beaudoin, L.2    Jeske, D.3    Carnaud, C.4    Lehuen, A.5
  • 49
    • 0033591685 scopus 로고    scopus 로고
    • Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis
    • Behar, S. M., Dascher, C. C., Grusby, M. J., Wang, C. R. & Brenner, M. B. Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. J. Exp. Med. 189, 1973-1980 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1973-1980
    • Behar, S.M.1    Dascher, C.C.2    Grusby, M.J.3    Wang, C.R.4    Brenner, M.B.5
  • 50
    • 0034327173 scopus 로고    scopus 로고
    • Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrella burgdorferi
    • Kumar, H., Belperron, A., Barthold, S. W. & Bockenstedt, L. K. Cutting edge: CD1d deficiency impairs murine host defense against the spirochete. Borrella burgdorferi. J. Immunol. 165, 4797-4801 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 4797-4801
    • Kumar, H.1    Belperron, A.2    Barthold, S.W.3    Bockenstedt, L.K.4
  • 51
    • 0036604214 scopus 로고    scopus 로고
    • Treatment with α-galactosyl-ceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive
    • Duthie, M. S. & Kahn, S. J. Treatment with α -galactosyl-ceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive. J. Immunol. 168, 5778-5785 (2002).
    • (2002) J. Immunol. , vol.168 , pp. 5778-5785
    • Duthie, M.S.1    Kahn, S.J.2
  • 52
    • 0036138267 scopus 로고    scopus 로고
    • During Trypanosoma cruzi infection CD1d-restricted NKT cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein
    • Duthie, M. S. et al. During Trypanosoma cruzi infection CD1d-restricted NKT cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein. Infect. Immun. 70, 36-48 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 36-48
    • Duthie, M.S.1
  • 53
    • 0035721964 scopus 로고    scopus 로고
    • CD1d-restricted NK T cells are dispensable for specific antibody responses and protective immunity against liver-stage malaria infection in mice
    • Romero, J. F., Eberl, G., MacDonald, H. R. & Corradin, G. CD1d-restricted NK T cells are dispensable for specific antibody responses and protective immunity against liver-stage malaria infection in mice. Parasite Immunol. 23, 267-269 (2001).
    • (2001) Parasite Immunol. , vol.23 , pp. 267-269
    • Romero, J.F.1    Eberl, G.2    MacDonald, H.R.3    Corradin, G.4
  • 54
    • 0035284816 scopus 로고    scopus 로고
    • Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells
    • Dao, T. et al. Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells. J. Immunol. 168, 3090-3097 (2001).
    • (2001) J. Immunol. , vol.168 , pp. 3090-3097
    • Dao, T.1
  • 55
    • 0030613856 scopus 로고    scopus 로고
    • Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors
    • Cui, J. et al. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 278, 1623-1626 (1997).
    • (1997) Science , vol.278 , pp. 1623-1626
    • Cui, J.1
  • 56
    • 0036645278 scopus 로고    scopus 로고
    • A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas
    • Crowe, N. Y., Smyth, M. J. & Godfrey, D. I. A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas. J. Exp. Med. 196, 119-127 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 119-127
    • Crowe, N.Y.1    Smyth, M.J.2    Godfrey, D.I.3
  • 57
    • 0034605065 scopus 로고    scopus 로고
    • Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers
    • Matsuda, J. L. et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp. Med. 192, 741-754 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 741-754
    • Matsuda, J.L.1
  • 58
    • 0033197917 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
    • Toura, I. et al. Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide. J. Immunol. 163, 2387-2391 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 2387-2391
    • Toura, I.1
  • 59
    • 12944255911 scopus 로고    scopus 로고
    • α-galactosylceramide-activated Vα 14 natural killer T cells mediate protection against murine malaria
    • Gonzalez-Aseguinolaza, G. et al. α-galactosylceramide-activated Vα14 natural killer T cells mediate protection against murine malaria. Proc. Natl Acad. Sci. USA 97, 8461-8466 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8461-8466
    • Gonzalez-Aseguinolaza, G.1
  • 60
    • 0034596944 scopus 로고    scopus 로고
    • Natural killer T-cell activation inhibits hepatitis B virus replication in vivo
    • Kakimi, K., Guidotti, L. G., Koezuka, Y. & Chisan, F. V. Natural killer T-cell activation inhibits hepatitis B virus replication in vivo. J. Exp. Med. 192, 921-930 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 921-930
    • Kakimi, K.1    Guidotti, L.G.2    Koezuka, Y.3    Chisan, F.V.4
  • 61
    • 0032933394 scopus 로고    scopus 로고
    • Natural T cells in the human liver: Cytotoxic lymphocytes with dual T-cell and natural-killer-cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T-cell-receptor-bearing cells
    • Norris, S. et al. Natural T cells in the human liver: cytotoxic lymphocytes with dual T-cell and natural-killer-cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T-cell-receptor-bearing cells. Hum. Immunol. 60, 20-31 (1999).
    • (1999) Hum. Immunol. , vol.60 , pp. 20-31
    • Norris, S.1
  • 62
    • 0029847625 scopus 로고    scopus 로고
    • RAG1, RAG2 and pre-T-cell receptor α-chain expression by adult human hepatic T cells: Evidence for extrathymic T-cell maturation
    • Collins, C. et al. RAG1, RAG2 and pre-T-cell receptor α-chain expression by adult human hepatic T cells: evidence for extrathymic T-cell maturation. Eur. J. Immunol. 26, 3114-3118 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 3114-3118
    • Collins, C.1
  • 63
    • 0032898463 scopus 로고    scopus 로고
    • In vitro evidence for the presence of hemetopoietic stem cells in the adult human liver
    • Crosbie, O. M. et al. In vitro evidence for the presence of hemetopoietic stem cells in the adult human liver. Hepatology 29, 1193-1198 (1999).
    • (1999) Hepatology , vol.29 , pp. 1193-1198
    • Crosbie, O.M.1
  • 64
    • 0031179507 scopus 로고    scopus 로고
    • + T cells but induces type I T cells in the liver by induction of IL-12 and IL-16 production from Kupffer cells
    • + T cells but induces type I T cells in the liver by induction of IL-12 and IL-16 production from Kupffer cells. J. Immunol. 159, 97-106 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 97-106
    • Matsui, K.1
  • 65
    • 0034005303 scopus 로고    scopus 로고
    • Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage
    • Guebre-Xabier, M. et al. Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. Hepatology 31, 633-640 (2000).
    • (2000) Hepatology , vol.31 , pp. 633-640
    • Guebre-Xabier, M.1
  • 66
    • 0034106520 scopus 로고    scopus 로고
    • Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation
    • Minagawa, M. et al. Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation. Hepatology 31, 907-915 (2000).
    • (2000) Hepatology , vol.31 , pp. 907-915
    • Minagawa, M.1
  • 67
    • 0029038708 scopus 로고
    • Murine hepatitis caused by lymphocytic choriomeningitis virus. II. Cells involved in pathogenesis
    • Gossmann, J., Lohler, J., Utermohlen, O. & Lehmann-Grube, F. Murine hepatitis caused by lymphocytic choriomeningitis virus. II. Cells involved in pathogenesis. Lab. Invest. 72, 559-570 (1995).
    • (1995) Lab. Invest. , vol.72 , pp. 559-570
    • Gossmann, J.1    Lohler, J.2    Utermohlen, O.3    Lehmann-Grube, F.4
  • 68
    • 0025478535 scopus 로고
    • Comparisons of peripheral blood and hepatic lymphocyte subpopulations and interferon production in chronic viral hepatitis
    • Kakumu, S. et al. Comparisons of peripheral blood and hepatic lymphocyte subpopulations and interferon production in chronic viral hepatitis. J. Clin. Lab. Immunol. 33, 1-6 (1990).
    • (1990) J. Clin. Lab. Immunol. , vol.33 , pp. 1-6
    • Kakumu, S.1
  • 69
    • 0028038287 scopus 로고
    • + ratio of liver-derived lymphocytes correlates with viral replication in chronic hepatitis B
    • + ratio of liver-derived lymphocytes correlates with viral replication in chronic hepatitis B. Clin. Exp. Immunol. 97, 403-410 (1994).
    • (1994) Clin. Exp. Immunol. , vol.97 , pp. 403-410
    • Pham, B.N.1
  • 70
    • 0031325819 scopus 로고    scopus 로고
    • CD45RA and CD45RO isoform expression on intrahepatic T-lymphocytes in chronic hepatitis C
    • Fiore, G. et al. CD45RA and CD45RO isoform expression on intrahepatic T-lymphocytes in chronic hepatitis C. Microbios. 92, 73-82 (1997).
    • (1997) Microbios. , vol.92 , pp. 73-82
    • Fiore, G.1
  • 71
    • 0035035656 scopus 로고    scopus 로고
    • Characterization of liver T-cell receptor γδ T cells obtained from individuals chronically infected with hepatitis C virus (HCV): Evidence for these T cells playing a role in the liver pathology associated with HCV infections
    • Tseng, C. T., Miskovsky, E., Houghton, M. & Kimpel, G. R. Characterization of liver T-cell receptor γδ T cells obtained from individuals chronically infected with hepatitis C virus (HCV): evidence for these T cells playing a role in the liver pathology associated with HCV infections. Hepatology 33, 1312-1320 (2001).
    • (2001) Hepatology , vol.33 , pp. 1312-1320
    • Tseng, C.T.1    Miskovsky, E.2    Houghton, M.3    Kimpel, G.R.4
  • 72
    • 0034078355 scopus 로고    scopus 로고
    • The liver as a site of T-cell apoptosis: Graveyard, or killing field?
    • Crispe, I. N., Dao, T., Klugewitz, K., Mehal, W. Z. & Metz, D. P. The liver as a site of T-cell apoptosis: graveyard, or killing field? Immunol. Rev. 174, 47-62 (2000).
    • (2000) Immunol. Rev. , vol.174 , pp. 47-62
    • Crispe, I.N.1    Dao, T.2    Klugewitz, K.3    Mehal, W.Z.4    Metz, D.P.5
  • 73
    • 0025293787 scopus 로고
    • Hepatic expression of intercellular adhesion molecule-1 (ICAM-1) in viral hepatitis B
    • Volpes, R., van den Oord, J. J. & Desmet, V. J. Hepatic expression of intercellular adhesion molecule-1 (ICAM-1) in viral hepatitis B. Hepatology 12, 148-154 (1990).
    • (1990) Hepatology , vol.12 , pp. 148-154
    • Volpes, R.1    Van den Oord, J.J.2    Desmet, V.J.3
  • 74
    • 0028873160 scopus 로고
    • Vascular adhesion molecule expression in viral chronic hepatitis: Evidence of neoangiogenesis in portal tracts
    • Garcia-Monzon, C. et al. Vascular adhesion molecule expression in viral chronic hepatitis: evidence of neoangiogenesis in portal tracts. Gastroenterology 108, 231-241 (1995).
    • (1995) Gastroenterology , vol.108 , pp. 231-241
    • Garcia-Monzon, C.1
  • 75
    • 0031050891 scopus 로고    scopus 로고
    • B7/BB-1 expression and hepatitis activity in liver tissues of patients with chronic hepatitis C
    • Mochizuki, K. et al. B7/BB-1 expression and hepatitis activity in liver tissues of patients with chronic hepatitis C. Hepatology 25, 713-718 (1997).
    • (1997) Hepatology , vol.25 , pp. 713-718
    • Mochizuki, K.1
  • 76
    • 0028200655 scopus 로고
    • Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C
    • Hiramatsu, N. et al. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 19, 1354-1359 (1994).
    • (1994) Hepatology , vol.19 , pp. 1354-1359
    • Hiramatsu, N.1
  • 78
    • 0031010858 scopus 로고    scopus 로고
    • A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature
    • Wong, J. et al. A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J. Clin. Invest. 99, 2782-2790 (1997).
    • (1997) J. Clin. Invest. , vol.99 , pp. 2782-2790
    • Wong, J.1
  • 79
    • 0030829292 scopus 로고    scopus 로고
    • Constitutive expression of ICAM-1 in rat microvascular systems analyzed by laser confocal microscopy
    • Iigo, Y. et al. Constitutive expression of ICAM-1 in rat microvascular systems analyzed by laser confocal microscopy. Am. J. Physiol. 273, H138-H147 (1997).
    • (1997) Am. J. Physiol. , vol.273
    • Iigo, Y.1
  • 80
    • 0030044722 scopus 로고    scopus 로고
    • Vascular adhesion protein 1 mediates binding of T cells to human hepatic endothelium
    • McNab, G. et al. Vascular adhesion protein 1 mediates binding of T cells to human hepatic endothelium. Gastroenterology 110, 522-528 (1996).
    • (1996) Gastroenterology , vol.110 , pp. 522-528
    • McNab, G.1
  • 81
    • 0035193173 scopus 로고    scopus 로고
    • Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice
    • Harju, K., Glumoff, V. & Hallman, M. Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice. Pediatr. Res. 49, 81-83 (2001).
    • (2001) Pediatr. Res. , vol.49 , pp. 81-83
    • Harju, K.1    Glumoff, V.2    Hallman, M.3
  • 82
    • 0035253370 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: Role of NF-κB activation
    • Faure, E. et al. Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-κB activation. J. Immunol. 166, 2018-2024 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 2018-2024
    • Faure, E.1
  • 83
    • 0028791035 scopus 로고
    • Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo
    • van Oosten, M., van de Bilt, E., de Vries, H. E., van Berkel, T. J. & Kuiper, J. Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo. Hepatology 22, 1538-1546 (1995).
    • (1995) Hepatology , vol.22 , pp. 1538-1546
    • Van Oosten, M.1    Van de Bilt, E.2    De Vries, H.E.3    Van Berkel, T.J.4    Kuiper, J.5
  • 84
    • 0029911692 scopus 로고    scopus 로고
    • A life stage of particle-laden rat dendritic cells in vivo: Their terminal division, active phagocytosis and translocation from the liver to the draining lymph
    • Matsuno, K., Ezaki, T., Kudo, S. & Uehara, Y. A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis and translocation from the liver to the draining lymph. J. Exp. Med. 183, 1865-1878 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1865-1878
    • Matsuno, K.1    Ezaki, T.2    Kudo, S.3    Uehara, Y.4
  • 85
    • 0031849974 scopus 로고    scopus 로고
    • Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites
    • Dieu, M. C. et al. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188, 373-386 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 373-386
    • Dieu, M.C.1
  • 86
    • 0033105359 scopus 로고    scopus 로고
    • Cutting edge: Secondary lymphoid-tissue chemokine (SLC) and CC-chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
    • Saeki, H., Moore, A. M., Brown, M. J. & Hwang, S. T. Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC-chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 162, 2472-2475 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 2472-2475
    • Saeki, H.1    Moore, A.M.2    Brown, M.J.3    Hwang, S.T.4
  • 87
    • 0035182253 scopus 로고    scopus 로고
    • Regulation by chemokines of circulating dendritic-cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease
    • Yoneyama, H. et al. Regulation by chemokines of circulating dendritic-cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. J. Exp. Med. 193, 35-49 (2001).
    • (2001) J. Exp. Med. , vol.193 , pp. 35-49
    • Yoneyama, H.1
  • 88
    • 0024267418 scopus 로고
    • Characterization of interstitial dendritic cells in human liver
    • Prickett, T. C., McKenzie, J. L. & Hart, D. N. Characterization of interstitial dendritic cells in human liver. Transplantation 46, 754-761 (1988).
    • (1988) Transplantation , vol.46 , pp. 754-761
    • Prickett, T.C.1    McKenzie, J.L.2    Hart, D.N.3
  • 89
    • 0034670385 scopus 로고    scopus 로고
    • Development of CD8α-positive dendritic cells from a common myeloid progenitor
    • Traver, D. et al. Development of CD8α-positive dendritic cells from a common myeloid progenitor. Science 290, 2152-2154 (2000).
    • (2000) Science , vol.290 , pp. 2152-2154
    • Traver, D.1
  • 91
    • 0035207270 scopus 로고    scopus 로고
    • Kupffer-cell-mediated recruitment of rat dendritic cells to the liver: Roles of N-acetylgalactosamine-specific sugar receptors
    • Uwatoku, R. et al. Kupffer-cell-mediated recruitment of rat dendritic cells to the liver: roles of N-acetylgalactosamine-specific sugar receptors. Gastroenterology 121, 1460-1472 (2001).
    • (2001) Gastroenterology , vol.121 , pp. 1460-1472
    • Uwatoku, R.1
  • 92
    • 0034989064 scopus 로고    scopus 로고
    • Asialoglycoprotein receptors on rat dendritic cells: Possible roles for binding with Kupffer cells and ingesting virus particles
    • Uwatoku, R. et al. Asialoglycoprotein receptors on rat dendritic cells: possible roles for binding with Kupffer cells and ingesting virus particles. Arch. Histol. Cytol. 64, 223-232 (2001).
    • (2001) Arch. Histol. Cytol. , vol.64 , pp. 223-232
    • Uwatoku, R.1
  • 93
    • 18544381567 scopus 로고    scopus 로고
    • The macrophage C-type lectin specific for galactose/ N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells
    • Higashi, N. et al. The macrophage C-type lectin specific for galactose/N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells. J. Biol. Chem. 277, 20686-20693 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 20686-20693
    • Higashi, N.1
  • 94
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class-I-restricted CTLs
    • Albert, M. L., Sauter, B. & Bhardwaj, N. Dendritic cells acquire antigen from apoptotic cells and induce class-I-restricted CTLs. Nature 392, 86-89 (1998).
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 95
    • 3543053363 scopus 로고    scopus 로고
    • 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
    • 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J. Exp. Med. 188, 1359-1368 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1359-1368
    • Albert, M.L.1
  • 96
    • 0029978748 scopus 로고    scopus 로고
    • Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells
    • Lohse, A. W. et al. Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology 110, 1175-1181 (1996).
    • (1996) Gastroenterology , vol.110 , pp. 1175-1181
    • Lohse, A.W.1
  • 98
    • 0034533209 scopus 로고    scopus 로고
    • + T cells results in antigen-specific T-cell tolerance
    • + T cells results in antigen-specific T-cell tolerance. Nature Med. 6, 1348-1354 (2000). In this paper, Knolle and colleagues describe the unique properties of liver sinusoidal endothelial cells as antigen-presenting cells that promote tolerance.
    • (2000) Nature Med. , vol.6 , pp. 1348-1354
    • Limmer, A.1
  • 99
    • 0033058997 scopus 로고    scopus 로고
    • Enhanced expression of CD80 (B7-1), CD86 (B7-2) and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure
    • Leifeld, L. et al. Enhanced expression of CD80 (B7-1), CD86 (B7-2) and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure. Am. J. Pathol. 154, 1711-1720 (1999).
    • (1999) Am. J. Pathol. , vol.154 , pp. 1711-1720
    • Leifeld, L.1
  • 100
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust, D., Vezys, V. Marzo, A. L. & Lefrancois, L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 291, 2413-2417 (2001).
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 101
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt, R. L., Khoruts, A., Merica, R., Zell, T. & Jenkins, M. K. Visualizing the generation of memory CD4 T cells in the whole body. Nature 410, 101-105 (2001).
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 104
    • 2642674430 scopus 로고    scopus 로고
    • + T lymphocytes but fail to promote survival
    • + T lymphocytes but fail to promote survival. Eur. J. Immunol. 28, 221-236 (1998). One explanation for liver tolerance is that antigen presentation by non-professional antigen-presenting cells, such as hepatocytes, causes T-cell apoptosis. This paper describes experiments in favour of this theory.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 221-236
    • Bertolino, P.1    Trescol-Biemont, M.C.2    Rabourdin-Combe, C.3
  • 105
    • 0345004951 scopus 로고    scopus 로고
    • Death by neglect as a deletional mechanism of peripheral tolerance
    • Bertolino, P. et al. Death by neglect as a deletional mechanism of peripheral tolerance. Int. Immunol. 11, 1225-1238 (1999).
    • (1999) Int. Immunol. , vol.11 , pp. 1225-1238
    • Bertolino, P.1
  • 106
    • 0031570116 scopus 로고    scopus 로고
    • Apoptosis within spontaneously accepted mouse liver allografts: Evidence for deletion of cytotoxic T cells and implications for tolerance induction
    • Qian, S. et al. Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction. J. Immunol. 158, 4654-4661 (1997). Qian and colleagues show that apoptosis is an important feature of the lymphocyte influx to a liver allograft.
    • (1997) J. Immunol. , vol.158 , pp. 4654-4661
    • Qian, S.1
  • 107
    • 0344889014 scopus 로고    scopus 로고
    • Apoptosis of alloreactive T cells in liver allografts during tolerance induction
    • Meyer, D. et al. Apoptosis of alloreactive T cells in liver allografts during tolerance induction. Transplant. Proc. 31, 474 (1999).
    • (1999) Transplant. Proc. , vol.31 , pp. 474
    • Meyer, D.1
  • 108
    • 0029817246 scopus 로고    scopus 로고
    • T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions
    • Lohman, B. L., Razvi, E. S. & Welsh, R. M. T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions. J. Virol 70, 8199-8203 (1996).
    • (1996) J. Virol , vol.70 , pp. 8199-8203
    • Lohman, B.L.1    Razvi, E.S.2    Welsh, R.M.3
  • 109
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo, M. et al. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17, 221-253 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 221-253
    • Lenardo, M.1
  • 110
    • 0033009890 scopus 로고    scopus 로고
    • The central effectors of cell death in the immune system
    • Rathmell, J. C. & Thompson, C. B. The central effectors of cell death in the immune system. Annu. Rev. Immunol. 17, 781-828 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 781-828
    • Rathmell, J.C.1    Thompson, C.B.2
  • 111
    • 0032785181 scopus 로고    scopus 로고
    • Serial killers: Ordering caspase activation events in apoptosis
    • Slee, E. A., Adrain, C. & Martin, S. J. Serial killers: ordering caspase activation events in apoptosis. Cell Death Differ. 6, 1067-1074 (1999).
    • (1999) Cell Death Differ. , vol.6 , pp. 1067-1074
    • Slee, E.A.1    Adrain, C.2    Martin, S.J.3
  • 112
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse αβ T lymphocytes for apoptosis
    • Lenardo, M. J. Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 353, 858-861 (1991).
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 113
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T-cell apoptosis
    • Refaeli, Y., Ven Parijs, L., London, C. A., Tschopp, J. & Abbas, A. K. Biochemical mechanisms of IL-2-regulated Fas-mediated T-cell apoptosis. Immunity 8, 615-623 (1998)
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    Ven Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 114
    • 0033426959 scopus 로고    scopus 로고
    • Autoimmmunity as a consequence of retrovirus-mediated expression of c-FLIP in lymphocytes
    • Van Parijs, L., Refaeli, Y., Abbas, A. K. & Baltimore, D. Autoimmmunity as a consequence of retrovirus-mediated expression of c-FLIP in lymphocytes. Immunity 11, 763-770 (1999).
    • (1999) Immunity , vol.11 , pp. 763-770
    • Van Parijs, L.1    Refaeli, Y.2    Abbas, A.K.3    Baltimore, D.4
  • 115
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema, J. P. et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16, 2794-2804 (1997).
    • (1997) EMBO J. , vol.16 , pp. 2794-2804
    • Medema, J.P.1
  • 116
    • 0344026088 scopus 로고    scopus 로고
    • Hepatocytes and liver nonparenchymal cells induce apoptosis in activated T cells
    • Lee, Y. C. et al. Hepatocytes and liver nonparenchymal cells induce apoptosis in activated T cells. Transplant. Proc. 31, 784 (1999).
    • (1999) Transplant. Proc. , vol.31 , pp. 784
    • Lee, Y.C.1
  • 117
    • 0025791940 scopus 로고
    • Clonal energy is induced in vitro by T-cell receptor occupancy in the absence of proliferation
    • DeSilva, D. R., Urdahl, K. B. & Jenkins, M. K. Clonal energy is induced in vitro by T-cell receptor occupancy in the absence of proliferation. J. Immunol. 147, 3261-3267 (1991).
    • (1991) J. Immunol. , vol.147 , pp. 3261-3267
    • DeSilva, D.R.1    Urdahl, K.B.2    Jenkins, M.K.3
  • 118
    • 0035960387 scopus 로고    scopus 로고
    • Costimulation blockade promotes the apoptotic death of graft-infiltrating T cells and prolongs survival of hepatic allografts from FLT3L-treated donors
    • Li, W. et al. Costimulation blockade promotes the apoptotic death of graft-infiltrating T cells and prolongs survival of hepatic allografts from FLT3L-treated donors. Transplantation 72, 1423-1432 (2001).
    • (2001) Transplantation , vol.72 , pp. 1423-1432
    • Li, W.1
  • 119
    • 0035284708 scopus 로고    scopus 로고
    • Fas-mediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver
    • Liu, Z. X., Govindarajan, S., Okamoto, S. & Dennert, G. Fas-mediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver. J. Immunol. 166, 3035-3041 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 3035-3041
    • Liu, Z.X.1    Govindarajan, S.2    Okamoto, S.3    Dennert, G.4
  • 120
    • 17944394558 scopus 로고    scopus 로고
    • Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells
    • Bonfoco, E. et al. Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity 9, 711-720 (1998).
    • (1998) Immunity , vol.9 , pp. 711-720
    • Bonfoco, E.1
  • 122
    • 0034328892 scopus 로고    scopus 로고
    • Uncoupling of inflammatory chemokine receptors by IL-10: Generation of functional decoys
    • D'Amico, G. et al. Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys. Nature Immunol. 1, 387-391 (2000).
    • (2000) Nature Immunol. , vol.1 , pp. 387-391
    • D'Amico, G.1
  • 123
    • 0035876929 scopus 로고    scopus 로고
    • Mammalian and viral IL-10 enhance CC-chemokine receptor 5 but down-regulate CC-chemokine receptor 7 expression by myeloid dendritic cells: Impact on chemotactic responses and in vivo homing ability
    • Takayama, T. et al. Mammalian and viral IL-10 enhance CC-chemokine receptor 5 but down-regulate CC-chemokine receptor 7 expression by myeloid dendritic cells: impact on chemotactic responses and in vivo homing ability. J. Immunol. 166, 7136-7143 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 7136-7143
    • Takayama, T.1
  • 124
    • 0036584686 scopus 로고    scopus 로고
    • + T cells produce different cytokines during rejection and tolerance in response to stimulation
    • + T cells produce different cytokines during rejection and tolerance in response to stimulation. J. Gastrointest. Surg. 6, 455-463 (2002).
    • (2002) J. Gastrointest. Surg. , vol.6 , pp. 455-463
    • Otto, C.1
  • 126
    • 0035423390 scopus 로고    scopus 로고
    • IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA or lipopolysaccharide and promotes dendritic-cell activation
    • Mattei, F., Schiavoni, G., Belardelli, F. & Tough, D. F. IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA or lipopolysaccharide and promotes dendritic-cell activation. J. Immunol. 167, 1179-1187 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 1179-1187
    • Mattei, F.1    Schiavoni, G.2    Belardelli, F.3    Tough, D.F.4
  • 127
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • Lutz, M. & Schuler, G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol. 23, 445-449 (2002).
    • (2002) Trends Immunol. , vol.23 , pp. 445-449
    • Lutz, M.1    Schuler, G.2
  • 128
    • 0036136282 scopus 로고    scopus 로고
    • Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells
    • Christensen, H. R., Frokiaer, H. & Pestka, J. J. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol. 168, 171-178 (2002).
    • (2002) J. Immunol. , vol.168 , pp. 171-178
    • Christensen, H.R.1    Frokiaer, H.2    Pestka, J.J.3
  • 130
    • 0032529213 scopus 로고    scopus 로고
    • Type I IFNs enhance the terminal differentiation of dendritic cells
    • Luft, T. et al. Type I IFNs enhance the terminal differentiation of dendritic cells. J. Immunol. 161, 1947-1953 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 1947-1953
    • Luft, T.1
  • 131
    • 0032744680 scopus 로고    scopus 로고
    • Low levels of interferon-α induce CD86 (B7.2) expression and accelerate dendritic-cell maturation from human peripheral-blood mononuclear cells
    • Radvanyi, L. G., Banerjee, A., Weir M. & Messner, H. Low levels of interferon-α induce CD86 (B7.2) expression and accelerate dendritic-cell maturation from human peripheral-blood mononuclear cells. Scand. J. Immunol. 50, 499-509 (1999).
    • (1999) Scand. J. Immunol. , vol.50 , pp. 499-509
    • Radvanyi, L.G.1    Banerjee, A.2    Weir, M.3    Messner, H.4
  • 132
    • 0034679566 scopus 로고    scopus 로고
    • Natural interferon-αβ-producing cells link innate and adaptive immunity
    • Kadowaki, N., Antonenko, S., Lau, J. Y. & Liu, Y. J. Natural interferon-αβ-producing cells link innate and adaptive immunity. J. Exp. Med. 192, 219-226 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 219-226
    • Kadowaki, N.1    Antonenko, S.2    Lau, J.Y.3    Liu, Y.J.4
  • 133
    • 0033082475 scopus 로고    scopus 로고
    • Endotoxin down-regulates T-cell activation by antigen-presenting liver sinusoidal endothelial cells
    • Knolle, P. A. et al. Endotoxin down-regulates T-cell activation by antigen-presenting liver sinusoidal endothelial cells. J. Immunol. 162, 1401-1407 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 1401-1407
    • Knolle, P.A.1
  • 134
    • 0027291205 scopus 로고
    • Lethal effects of the anti-Fas antibody in mice
    • Ogasawara, J. et al. Lethal effects of the anti-Fas antibody in mice. Nature 346, 806-809 (1993).
    • (1993) Nature , vol.346 , pp. 806-809
    • Ogasawara, J.1
  • 135
    • 0033807015 scopus 로고    scopus 로고
    • Induction of murine hepatocyte death by membrane-bound CD95 (Fas/APO-1)-ligand: Characterization of an in vitro system
    • Schlosser, S. F. et al. Induction of murine hepatocyte death by membrane-bound CD95 (Fas/APO-1)-ligand: characterization of an in vitro system. Hepatology 32, 779-785 (2000).
    • (2000) Hepatology , vol.32 , pp. 779-785
    • Schlosser, S.F.1
  • 138
    • 0029862501 scopus 로고    scopus 로고
    • + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium
    • + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium. Proc. Natl Acad. Sci. USA 93, 11774-11779 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11774-11779
    • Roberts, S.J.1
  • 139
    • 0028117098 scopus 로고
    • Modulation of epithelial-cell growth by intraepithelial γδ T cells
    • Boismenu, R. & Havran, W. Modulation of epithelial-cell growth by intraepithelial γδ T cells. Science 266, 1253-1255 (1994).
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.2
  • 140
    • 0031754989 scopus 로고    scopus 로고
    • FK506 promotes liver regeneration by suppressing natural killer cell activity
    • Tamura, F. et al. FK506 promotes liver regeneration by suppressing natural killer cell activity. J. Gastroenterol. Hepatol. 13, 703-708 (1998).
    • (1998) J. Gastroenterol. Hepatol. , vol.13 , pp. 703-708
    • Tamura, F.1
  • 141
    • 0034121972 scopus 로고    scopus 로고
    • Molecular mechanisms of augmenter of liver regeneration as immunoregulator: Its effect on interferon-7 expression in rat liver
    • Polimeno, L. et al. Molecular mechanisms of augmenter of liver regeneration as immunoregulator: its effect on interferon-7 expression in rat liver. Dig. Liver Dis. 32, 217-225 (2000).
    • (2000) Dig. Liver Dis. , vol.32 , pp. 217-225
    • Polimeno, L.1
  • 142
    • 0032555920 scopus 로고    scopus 로고
    • + T cells triggered by high-affinity peptide antigens
    • + T cells triggered by high-affinity peptide antigens. J. Exp. Med. 188, 1147-1157 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1147-1157
    • Russell, J.Q.1
  • 144
    • 0032885603 scopus 로고    scopus 로고
    • Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis
    • Hayashi, N. & Mita, E. Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis. J. Viral Hepat. 6, 357-365 (1999).
    • (1999) J. Viral Hepat. , vol.6 , pp. 357-365
    • Hayashi, N.1    Mita, E.2
  • 145
    • 0032618720 scopus 로고    scopus 로고
    • Liver tissue expression of CD80 and CD95 antigens in chronic hepatitis C: Relationship with biological and histological disease activities
    • Fiore, G. et al. Liver tissue expression of CD80 and CD95 antigens in chronic hepatitis C: relationship with biological and histological disease activities. Microbios. 97, 29-38 (1999).
    • (1999) Microbios. , vol.97 , pp. 29-38
    • Fiore, G.1
  • 146
    • 0035076327 scopus 로고    scopus 로고
    • Fas antigen expression on hepatocytes predicts the short- and long-term response to interferon therapy in patients with chronic hepatitis C
    • Abe, S., Kotoh, K., Arao, S., Tabaru, A. & Otsuki, M. Fas antigen expression on hepatocytes predicts the short- and long-term response to interferon therapy in patients with chronic hepatitis C. Scand. J. Gastroenterol. 36, 326-331 (2001).
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 326-331
    • Abe, S.1    Kotoh, K.2    Arao, S.3    Tabaru, A.4    Otsuki, M.5
  • 147
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo, T., Suda, T., Fukuyama, H., Adachi, M. & Nagata, S. Essential roles of the Fas ligand in the development of hepatitis. Nature Med. 3, 409-413 (1997).
    • (1997) Nature Med. , vol.3 , pp. 409-413
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 148
    • 0031279189 scopus 로고    scopus 로고
    • Fas-mediated liver damage in MRL hemopoietic chimeras undergoing lpr-mediated graft-versus-host disease
    • Bobe, P. et al. Fas-mediated liver damage in MRL hemopoietic chimeras undergoing lpr-mediated graft-versus-host disease. J. Immunol. 159, 4197-4204 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 4197-4204
    • Bobe, P.1
  • 149
    • 0033579819 scopus 로고    scopus 로고
    • CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell-surface Fas-ligand expression and amplifies Fas-mediated hepatocyte death during allograft rejection
    • Afford, S. C. et al. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell-surface Fas-ligand expression and amplifies Fas-mediated hepatocyte death during allograft rejection. J. Exp. Med. 189, 441-446 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 441-446
    • Afford, S.C.1
  • 150
    • 0033932001 scopus 로고    scopus 로고
    • Recovery, persistence and sequelae in hepatitis C virus infection: A perspective on long-term outcome
    • Alter, H. J. & Seeff, L. B. Recovery, persistence and sequelae in hepatitis C virus infection: a perspective on long-term outcome. Semin. Liver Dis. 20, 17-35 (2000).
    • (2000) Semin. Liver Dis. , vol.20 , pp. 17-35
    • Alter, H.J.1    Seeff, L.B.2
  • 151
    • 0031915132 scopus 로고    scopus 로고
    • Liver-derived CTL in hepatitis C virus infection: Breadth and specificity of responses in a cohort of persons with chronic infection
    • Wong, D. K. et al. Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. J. Immunol. 160, 1479-1488 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 1479-1488
    • Wong, D.K.1
  • 152
    • 0033829854 scopus 로고    scopus 로고
    • + T-lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
    • + T-lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur. J. Immunol. 30, 2479-2487 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2479-2487
    • Lechner, F.1
  • 153
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner, F. et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J. Exp. Med. 191, 1499-1512 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 1499-1512
    • Lechner, F.1
  • 154
    • 0033119925 scopus 로고    scopus 로고
    • Analysis of a successful immune response against hepatitis C virus
    • Cooper, S. et al. Analysis of a successful immune response against hepatitis C virus. Immunity 10, 439-449 (1999). This paper shows the importance of the magnitude and diversity of the cytotoxic T-lymphocyte response in determining the outcome of hepatitis C virus infection.
    • (1999) Immunity , vol.10 , pp. 439-449
    • Cooper, S.1
  • 155
    • 0028968636 scopus 로고
    • Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant
    • Weiner, A. et al. Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant. Proc. Natl Acad Sci. USA 92, 2755-2759 (1995).
    • (1995) Proc. Natl. Acad Sci. USA , vol.92 , pp. 2755-2759
    • Weiner, A.1
  • 156
    • 18244397979 scopus 로고    scopus 로고
    • The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes
    • Erickson, A. L. et al. The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. Immunity 15, 883-895 (2001).
    • (2001) Immunity , vol.15 , pp. 883-895
    • Erickson, A.L.1
  • 157
    • 0030671121 scopus 로고    scopus 로고
    • Immunological significance of cytotoxic T-lymphocyte epitope variants in patients chronically infected by the hepatitis C virus
    • Chang, K. M. et al. Immunological significance of cytotoxic T-lymphocyte epitope variants in patients chronically infected by the hepatitis C virus. J. Clin. Invest. 100, 2376-2385 (1997).
    • (1997) J. Clin. Invest. , vol.100 , pp. 2376-2385
    • Chang, K.M.1
  • 158
    • 0033565792 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J. Immunol. 163, 650-658 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 650-658
    • Frasca, L.1
  • 159
    • 0035000769 scopus 로고    scopus 로고
    • + T lymphocytes after infection with hepatitis C virus
    • + T lymphocytes after infection with hepatitis C virus. J. Virol. 75, 5550-5558 (2001).
    • (2001) J. Virol. , vol.75 , pp. 5550-5558
    • Gruener, N.H.1
  • 160
    • 0033690901 scopus 로고    scopus 로고
    • Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation
    • Kittlesen, C. J., Chianese-Bullock, K. A., Yao, Z. Q., Braciale, T. J. & Hahn, Y. S. Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. J. Clin. Invest. 106, 1239-1249 (2000).
    • (2000) J. Clin. Invest. , vol.106 , pp. 1239-1249
    • Kittlesen, C.J.1    Chianese-Bullock, K.A.2    Yao, Z.Q.3    Braciale, T.J.4    Hahn, Y.S.5
  • 161
    • 0035500651 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits human T-lymphocyte responses by a complement-dependent regulatory pathway
    • Yao, Z. Q., Nguyen, D. T., Hiotellis, A. I. & Hahn, Y. S. Hepatitis C virus core protein inhibits human T-lymphocyte responses by a complement-dependent regulatory pathway. J. Immunol. 167, 5264-5272 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 5264-5272
    • Yao, Z.Q.1    Nguyen, D.T.2    Hiotellis, A.I.3    Hahn, Y.S.4
  • 162
    • 0034633835 scopus 로고    scopus 로고
    • The HCV core protein acts as a positive regulator of Fas-mediated apoptosis in a human lymphoblastoid T-cell line
    • Hahn, C. S., Cho, Y. G., Kang, B. S., Lester, I. M. & Hahn, Y. S. The HCV core protein acts as a positive regulator of Fas-mediated apoptosis in a human lymphoblastoid T-cell line. Virology 216, 127-137 (2000).
    • (2000) Virology , vol.216 , pp. 127-137
    • Hahn, C.S.1    Cho, Y.G.2    Kang, B.S.3    Lester, I.M.4    Hahn, Y.S.5
  • 163
    • 0037033359 scopus 로고    scopus 로고
    • Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein
    • Crotta, S. et al. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J. Exp. Med. 195, 35-42 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 35-42
    • Crotta, S.1
  • 164
    • 0035202411 scopus 로고    scopus 로고
    • Hepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection
    • Sun, J. et al. Hepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection. J. Virol. 75, 11992-11998 (2001).
    • (2001) J. Virol. , vol.75 , pp. 11992-11998
    • Sun, J.1
  • 165
    • 0026643743 scopus 로고
    • A T-cell-dependent experimental liver injury in mice inducible by concanavalin A
    • Tiegs, G., Hentschel, J. & Wendel, A. A T-cell-dependent experimental liver injury in mice inducible by concanavalin A. J. Clin. Invest. 90, 196-203 (1992).
    • (1992) J. Clin. Invest. , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 166
    • 0030806496 scopus 로고    scopus 로고
    • Experimental hepatitis and role of cytokines
    • Tiegs, G. Experimental hepatitis and role of cytokines. Acta Gastroenterol. Belg. 60, 176-179 (1997).
    • (1997) Acta Gastroenterol. Belg. , vol.60 , pp. 176-179
    • Tiegs, G.1
  • 168
    • 0027453541 scopus 로고
    • Mechanisms of class-1-restricted immunopathology. A transgenic mouse model of fulminant hepatitis
    • Ando, K. et al. Mechanisms of class-1-restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J. Exp. Med. 178, 1541-1554 (1993).
    • (1993) J. Exp. Med. , vol.178 , pp. 1541-1554
    • Ando, K.1
  • 169
    • 0031570505 scopus 로고    scopus 로고
    • Differential target-cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice
    • Nakamoto, Y., Guidotti, L. G., Pasquetto, V., Schreiber, R. D. & Chisari, F. V. Differential target-cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice. J. Immunol. 158, 5692-5697 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 5692-5697
    • Nakamoto, Y.1    Guidotti, L.G.2    Pasquetto, V.3    Schreiber, R.D.4    Chisari, F.V.5


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