메뉴 건너뛰기




Volumn 17, Issue 2 SPEC. ISS., 2005, Pages 105-119

DNA methylation and the expanding epigenetics of T cell lineage commitment

Author keywords

Chromatin; DNA methylation; Epigenetic; Histone; T cell

Indexed keywords

CD8 ANTIGEN; DNA; HISTONE; METHYL CPG BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 14244260068     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2005.01.005     Document Type: Article
Times cited : (113)

References (156)
  • 1
    • 0038638583 scopus 로고    scopus 로고
    • An epigenetic view of helper T cell differentiation
    • K.M. Ansel, D.U. Lee, and A. Rao An epigenetic view of helper T cell differentiation Nat Immunol 4 2003 616 623
    • (2003) Nat Immunol , vol.4 , pp. 616-623
    • Ansel, K.M.1    Lee, D.U.2    Rao, A.3
  • 2
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • G. Egger, G. Liang, A. Aparicio, and P.A. Jones Epigenetics in human disease and prospects for epigenetic therapy Nature 429 2004 457 463
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 3
    • 85015069067 scopus 로고    scopus 로고
    • Controlling the double helix
    • G. Felsenfeld, and M. Groudine Controlling the double helix Nature 421 2003 448 453
    • (2003) Nature , vol.421 , pp. 448-453
    • Felsenfeld, G.1    Groudine, M.2
  • 4
    • 0142216213 scopus 로고    scopus 로고
    • Methylation and demethylation in the regulation of genes, cells, and responses in the immune system
    • D.R. Fitzpatrick, and C.B. Wilson Methylation and demethylation in the regulation of genes, cells, and responses in the immune system Clin Immunol 109 2003 37 45
    • (2003) Clin Immunol , vol.109 , pp. 37-45
    • Fitzpatrick, D.R.1    Wilson, C.B.2
  • 5
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • E. Li Chromatin modification and epigenetic reprogramming in mammalian development Nat Rev Genet 3 2002 662 673
    • (2002) Nat Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 6
    • 0030792305 scopus 로고    scopus 로고
    • DNA methylation: Regulation of gene expression and role in the immune system
    • R. Mostoslavsky, and Y. Bergman DNA methylation: regulation of gene expression and role in the immune system Biochim Biophys Acta 1333 1997 F29 F50
    • (1997) Biochim Biophys Acta , vol.1333
    • Mostoslavsky, R.1    Bergman, Y.2
  • 7
    • 0036216109 scopus 로고    scopus 로고
    • Chromatin structure and gene regulation in the immune system
    • S.T. Smale, and A.G. Fisher Chromatin structure and gene regulation in the immune system Annu Rev Immunol 20 2002 427 462
    • (2002) Annu Rev Immunol , vol.20 , pp. 427-462
    • Smale, S.T.1    Fisher, A.G.2
  • 9
    • 0142247187 scopus 로고    scopus 로고
    • Mammalian DNA (cytosine-5) methyltransferases and their expression
    • S. Pradhan, and P.O. Esteve Mammalian DNA (cytosine-5) methyltransferases and their expression Clin Immunol 109 2003 6 16
    • (2003) Clin Immunol , vol.109 , pp. 6-16
    • Pradhan, S.1    Esteve, P.O.2
  • 10
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • M. Okano, S. Xie, and E. Li Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases Nat Genet 19 1998 219 220
    • (1998) Nat Genet , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 11
    • 0037068351 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells and the spread of DNA methylation
    • M.S. Turker Gene silencing in mammalian cells and the spread of DNA methylation Oncogene 21 2002 5388 5393
    • (2002) Oncogene , vol.21 , pp. 5388-5393
    • Turker, M.S.1
  • 12
    • 0037064088 scopus 로고    scopus 로고
    • A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation
    • T. Chen, Y. Ueda, S. Xie, and E. Li A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation J Biol Chem 277 2002 38746 38754
    • (2002) J Biol Chem , vol.277 , pp. 38746-38754
    • Chen, T.1    Ueda, Y.2    Xie, S.3    Li, E.4
  • 13
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • A. Bird DNA methylation patterns and epigenetic memory Genes Dev 16 2002 6 21
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 15
    • 0019905063 scopus 로고
    • Presence of a DNA demethylating activity in the nucleus of murine erythroleukemic cells
    • R.A. Gjerset, and D.W. Martin Jr. Presence of a DNA demethylating activity in the nucleus of murine erythroleukemic cells J Biol Chem 257 1982 8581 8583
    • (1982) J Biol Chem , vol.257 , pp. 8581-8583
    • Gjerset, R.A.1    Martin Jr., D.W.2
  • 16
    • 0242332183 scopus 로고    scopus 로고
    • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
    • W.G. Chen, Q. Chang, Y. Lin, A. Meissner, A.E. West, and E.C. Griffith Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2 Science 302 2003 885 889
    • (2003) Science , vol.302 , pp. 885-889
    • Chen, W.G.1    Chang, Q.2    Lin, Y.3    Meissner, A.4    West, A.E.5    Griffith, E.C.6
  • 17
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • K. Martinowich, D. Hattori, H. Wu, S. Fouse, F. He, and Y. Hu DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation Science 302 2003 890 893
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6
  • 18
    • 0037340215 scopus 로고    scopus 로고
    • Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
    • D. Bruniquel, and R.H. Schwartz Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process Nat Immunol 4 2003 235 240
    • (2003) Nat Immunol , vol.4 , pp. 235-240
    • Bruniquel, D.1    Schwartz, R.H.2
  • 19
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • P.H. Tate, and A.P. Bird Effects of DNA methylation on DNA-binding proteins and gene expression Curr Opin Genet Dev 3 1993 226 231
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 20
    • 0037406067 scopus 로고    scopus 로고
    • The methyl-CpG binding domain and the evolving role of DNA methylation in animals
    • B. Hendrich, and S. Tweedie The methyl-CpG binding domain and the evolving role of DNA methylation in animals Trends Genet 19 2003 269 277
    • (2003) Trends Genet , vol.19 , pp. 269-277
    • Hendrich, B.1    Tweedie, S.2
  • 21
    • 1842505317 scopus 로고    scopus 로고
    • Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains
    • H.F. Jorgensen, I. Ben-Porath, and A.P. Bird Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains Mol Cell Biol 24 2004 3387 3395
    • (2004) Mol Cell Biol , vol.24 , pp. 3387-3395
    • Jorgensen, H.F.1    Ben-Porath, I.2    Bird, A.P.3
  • 22
    • 0031792779 scopus 로고    scopus 로고
    • Identification and characterization of a family of mammalian methyl-CpG binding proteins
    • B. Hendrich, and A. Bird Identification and characterization of a family of mammalian methyl-CpG binding proteins Mol Cell Biol 18 1998 6538 6547
    • (1998) Mol Cell Biol , vol.18 , pp. 6538-6547
    • Hendrich, B.1    Bird, A.2
  • 23
    • 1342306393 scopus 로고    scopus 로고
    • Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF
    • M. Sekimata, and Y. Homma Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF Nucleic Acids Res 32 2004 590 597
    • (2004) Nucleic Acids Res , vol.32 , pp. 590-597
    • Sekimata, M.1    Homma, Y.2
  • 24
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: From genomic organization to genomic regulation
    • S. Khorasanizadeh The nucleosome: from genomic organization to genomic regulation Cell 116 2004 259 272
    • (2004) Cell , vol.116 , pp. 259-272
    • Khorasanizadeh, S.1
  • 25
    • 0037672689 scopus 로고    scopus 로고
    • An epigenetic road map for histone lysine methylation
    • M. Lachner, R.J. O'Sullivan, and T. Jenuwein An epigenetic road map for histone lysine methylation J Cell Sci 116 2003 2117 2124
    • (2003) J Cell Sci , vol.116 , pp. 2117-2124
    • Lachner, M.1    O'Sullivan, R.J.2    Jenuwein, T.3
  • 26
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • B.D. Strahl, and C.D. Allis The language of covalent histone modifications Nature 403 2000 41 45
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 27
    • 0038057380 scopus 로고    scopus 로고
    • Memorable transcription
    • B.M. Turner Memorable transcription Nat Cell Biol 5 2003 390 393
    • (2003) Nat Cell Biol , vol.5 , pp. 390-393
    • Turner, B.M.1
  • 30
    • 5044228483 scopus 로고    scopus 로고
    • Human PAD4 regulates histone arginine methylation levels via demethylimination
    • Y. Wang, J. Wysocka, J. Sayegh, Y.H. Lee, J.R. Perlin, and L. Leonelli Human PAD4 regulates histone arginine methylation levels via demethylimination Science 306 2004 279 283
    • (2004) Science , vol.306 , pp. 279-283
    • Wang, Y.1    Wysocka, J.2    Sayegh, J.3    Lee, Y.H.4    Perlin, J.R.5    Leonelli, L.6
  • 31
    • 1542347557 scopus 로고    scopus 로고
    • PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing
    • I. Gyory, J. Wu, G. Fejer, E. Seto, and K.L. Wright PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing Nat Immunol 5 2004 299 308
    • (2004) Nat Immunol , vol.5 , pp. 299-308
    • Gyory, I.1    Wu, J.2    Fejer, G.3    Seto, E.4    Wright, K.L.5
  • 33
    • 0029981561 scopus 로고    scopus 로고
    • Identification of a second conserved element within the coding sequence of a mouse H3 histone gene that interacts with nuclear factors and is necessary for normal expression
    • N.K. Kaludov, L. Pabon-Pena, and M.M. Hurt Identification of a second conserved element within the coding sequence of a mouse H3 histone gene that interacts with nuclear factors and is necessary for normal expression Nucleic Acids Res 24 1996 523 531
    • (1996) Nucleic Acids Res , vol.24 , pp. 523-531
    • Kaludov, N.K.1    Pabon-Pena, L.2    Hurt, M.M.3
  • 34
    • 0037058948 scopus 로고    scopus 로고
    • Histone H3 variants specify modes of chromatin assembly
    • K. Ahmad, and S. Henikoff Histone H3 variants specify modes of chromatin assembly Proc Natl Acad Sci USA 99 Suppl. 4 2002 16477 16484
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.4 SUPPL. , pp. 16477-16484
    • Ahmad, K.1    Henikoff, S.2
  • 35
    • 0742304304 scopus 로고    scopus 로고
    • Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
    • H. Tagami, D. Ray-Gallet, G. Almouzni, and Y. Nakatani Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis Cell 116 2004 51 61
    • (2004) Cell , vol.116 , pp. 51-61
    • Tagami, H.1    Ray-Gallet, D.2    Almouzni, G.3    Nakatani, Y.4
  • 36
    • 1242342240 scopus 로고    scopus 로고
    • Histone H3.3 is enriched in covalent modifications associated with active chromatin
    • E. McKittrick, P.R. Gafken, K. Ahmad, and S. Henikoff Histone H3.3 is enriched in covalent modifications associated with active chromatin Proc Natl Acad Sci USA 101 2004 1525 1530
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1525-1530
    • McKittrick, E.1    Gafken, P.R.2    Ahmad, K.3    Henikoff, S.4
  • 37
    • 4444267069 scopus 로고    scopus 로고
    • B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
    • K. Johnson, D.L. Pflugh, D. Yu, D.G. Hesslein, K.I. Lin, and A.L. Bothwell B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5 Nat Immunol 5 2004 853 861
    • (2004) Nat Immunol , vol.5 , pp. 853-861
    • Johnson, K.1    Pflugh, D.L.2    Yu, D.3    Hesslein, D.G.4    Lin, K.I.5    Bothwell, A.L.6
  • 39
    • 11144355550 scopus 로고    scopus 로고
    • SWRred not shaken; Mixing the histones
    • P. Korber, and W. Horz SWRred not shaken; mixing the histones Cell 117 2004 5 7
    • (2004) Cell , vol.117 , pp. 5-7
    • Korber, P.1    Horz, W.2
  • 40
    • 10244236502 scopus 로고    scopus 로고
    • A BAF-centered view of the immune system
    • T. Chi A BAF-centered view of the immune system Nat Rev Immunol 4 2004 965 977
    • (2004) Nat Rev Immunol , vol.4 , pp. 965-977
    • Chi, T.1
  • 41
    • 0035890090 scopus 로고    scopus 로고
    • Lsh, a member of the SNF2 family, is required for genome-wide methylation
    • K. Dennis, T. Fan, T. Geiman, Q. Yan, and K. Muegge Lsh, a member of the SNF2 family, is required for genome-wide methylation Genes Dev 15 2001 2940 2944
    • (2001) Genes Dev , vol.15 , pp. 2940-2944
    • Dennis, K.1    Fan, T.2    Geiman, T.3    Yan, Q.4    Muegge, K.5
  • 42
    • 0141642008 scopus 로고    scopus 로고
    • Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
    • Q. Yan, J. Huang, T. Fan, H. Zhu, and K. Muegge Lsh, a modulator of CpG methylation, is crucial for normal histone methylation EMBO J 22 2003 5154 5162
    • (2003) EMBO J , vol.22 , pp. 5154-5162
    • Yan, Q.1    Huang, J.2    Fan, T.3    Zhu, H.4    Muegge, K.5
  • 44
    • 0029964505 scopus 로고    scopus 로고
    • A preference of histone H1 for methylated DNA
    • M. McArthur, and J.O. Thomas A preference of histone H1 for methylated DNA EMBO J 15 1996 1705 1714
    • (1996) EMBO J , vol.15 , pp. 1705-1714
    • McArthur, M.1    Thomas, J.O.2
  • 45
    • 0041624239 scopus 로고    scopus 로고
    • Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: A mammalian cell culture model of gene variegation
    • K. Ayyanathan, M.S. Lechner, P. Bell, G.G. Maul, D.C. Schultz, and Y. Yamada Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation Genes Dev 17 2003 1855 1869
    • (2003) Genes Dev , vol.17 , pp. 1855-1869
    • Ayyanathan, K.1    Lechner, M.S.2    Bell, P.3    Maul, G.G.4    Schultz, D.C.5    Yamada, Y.6
  • 46
    • 0038412822 scopus 로고    scopus 로고
    • The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
    • F. Fuks, P.J. Hurd, R. Deplus, and T. Kouzarides The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase Nucleic Acids Res 31 2003 2305 2312
    • (2003) Nucleic Acids Res , vol.31 , pp. 2305-2312
    • Fuks, F.1    Hurd, P.J.2    Deplus, R.3    Kouzarides, T.4
  • 47
    • 0242348752 scopus 로고    scopus 로고
    • Histone lysine methylation: A signature for chromatin function
    • R.J. Sims 3rd, K. Nishioka, and D. Reinberg Histone lysine methylation: a signature for chromatin function Trends Genet 19 2003 629 639
    • (2003) Trends Genet , vol.19 , pp. 629-639
    • Sims III, R.J.1    Nishioka, K.2    Reinberg, D.3
  • 48
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • B.M. Turner Cellular memory and the histone code Cell 111 2002 285 291
    • (2002) Cell , vol.111 , pp. 285-291
    • Turner, B.M.1
  • 49
    • 4344685735 scopus 로고    scopus 로고
    • Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
    • S.A. Sarraf, and I. Stancheva Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly Mol Cell 15 2004 595 605
    • (2004) Mol Cell , vol.15 , pp. 595-605
    • Sarraf, S.A.1    Stancheva, I.2
  • 50
    • 0033883260 scopus 로고    scopus 로고
    • MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase
    • K.I. Tatematsu, T. Yamazaki, and F. Ishikawa MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase Genes Cells 5 2000 677 688
    • (2000) Genes Cells , vol.5 , pp. 677-688
    • Tatematsu, K.I.1    Yamazaki, T.2    Ishikawa, F.3
  • 52
    • 0038527642 scopus 로고    scopus 로고
    • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
    • L. Di Croce, V.A. Raker, M. Corsaro, F. Fazi, M. Fanelli, and M. Faretta Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor Science 295 2002 1079 1082
    • (2002) Science , vol.295 , pp. 1079-1082
    • Di Croce, L.1    Raker, V.A.2    Corsaro, M.3    Fazi, F.4    Fanelli, M.5    Faretta, M.6
  • 53
    • 0038581890 scopus 로고    scopus 로고
    • Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease
    • C. Tufarelli, J.A. Stanley, D. Garrick, J.A. Sharpe, H. Ayyub, and W.G. Wood Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease Nat Genet 34 2003 157 165
    • (2003) Nat Genet , vol.34 , pp. 157-165
    • Tufarelli, C.1    Stanley, J.A.2    Garrick, D.3    Sharpe, J.A.4    Ayyub, H.5    Wood, W.G.6
  • 54
    • 4143149753 scopus 로고    scopus 로고
    • Dicer is essential for formation of the heterochromatin structure in vertebrate cells
    • T. Fukagawa, M. Nogami, M. Yoshikawa, M. Ikeno, T. Okazaki, and Y. Takami Dicer is essential for formation of the heterochromatin structure in vertebrate cells Nat Cell Biol 6 2004 784 791
    • (2004) Nat Cell Biol , vol.6 , pp. 784-791
    • Fukagawa, T.1    Nogami, M.2    Yoshikawa, M.3    Ikeno, M.4    Okazaki, T.5    Takami, Y.6
  • 55
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • K.V. Morris, S.W. Chan, S.E. Jacobsen, and D.J. Looney Small interfering RNA-induced transcriptional gene silencing in human cells Science 305 2004 1289 1292
    • (2004) Science , vol.305 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.2    Jacobsen, S.E.3    Looney, D.J.4
  • 56
    • 4544242851 scopus 로고    scopus 로고
    • Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
    • H. Kawasaki, and K. Taira Induction of DNA methylation and gene silencing by short interfering RNAs in human cells Nature 431 2004 211 217
    • (2004) Nature , vol.431 , pp. 211-217
    • Kawasaki, H.1    Taira, K.2
  • 57
    • 0347719444 scopus 로고    scopus 로고
    • Methylation and epigenetic fidelity
    • A.D. Riggs, and Z. Xiong Methylation and epigenetic fidelity Proc Natl Acad Sci USA 101 2004 4 5
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4-5
    • Riggs, A.D.1    Xiong, Z.2
  • 58
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • A.P. Bird Gene number, noise reduction and biological complexity Trends Genet 11 1995 94 100
    • (1995) Trends Genet , vol.11 , pp. 94-100
    • Bird, A.P.1
  • 59
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • C.L. Hsieh Dependence of transcriptional repression on CpG methylation density Mol Cell Biol 14 1994 5487 5494
    • (1994) Mol Cell Biol , vol.14 , pp. 5487-5494
    • Hsieh, C.L.1
  • 60
    • 0029655782 scopus 로고    scopus 로고
    • DNA methylation specifies chromosomal localization of MeCP2
    • X. Nan, P. Tate, E. Li, and A. Bird DNA methylation specifies chromosomal localization of MeCP2 Mol Cell Biol 16 1996 414 421
    • (1996) Mol Cell Biol , vol.16 , pp. 414-421
    • Nan, X.1    Tate, P.2    Li, E.3    Bird, A.4
  • 61
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression - Belts, braces, and chromatin
    • A.P. Bird, and A.P. Wolffe Methylation-induced repression - belts, braces, and chromatin Cell 99 1999 451 454
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 64
    • 18244365863 scopus 로고    scopus 로고
    • A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
    • P.P. Lee, D.R. Fitzpatrick, C. Beard, H.K. Jessup, S. Lehar, and K.W. Makar A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival Immunity 15 2001 763 774
    • (2001) Immunity , vol.15 , pp. 763-774
    • Lee, P.P.1    Fitzpatrick, D.R.2    Beard, C.3    Jessup, H.K.4    Lehar, S.5    Makar, K.W.6
  • 66
    • 0035109547 scopus 로고    scopus 로고
    • DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals
    • G. Fan, C. Beard, R.Z. Chen, G. Csankovszki, Y. Sun, and M. Siniaia DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals J Neurosci 21 2001 788 797
    • (2001) J Neurosci , vol.21 , pp. 788-797
    • Fan, G.1    Beard, C.2    Chen, R.Z.3    Csankovszki, G.4    Sun, Y.5    Siniaia, M.6
  • 67
    • 0034712755 scopus 로고    scopus 로고
    • Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes
    • T.M. Geiman, and K. Muegge Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes Proc Natl Acad Sci USA 97 2000 4772 4777
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4772-4777
    • Geiman, T.M.1    Muegge, K.2
  • 68
    • 0141628697 scopus 로고    scopus 로고
    • Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin
    • Q. Yan, E. Cho, S. Lockett, and K. Muegge Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin Mol Cell Biol 23 2003 8416 8428
    • (2003) Mol Cell Biol , vol.23 , pp. 8416-8428
    • Yan, Q.1    Cho, E.2    Lockett, S.3    Muegge, K.4
  • 69
    • 0031892787 scopus 로고    scopus 로고
    • Biochemical and functional analyses of chromatin changes at the TCR-beta gene locus during CD4-CD8- to CD4+CD8+ thymocyte differentiation
    • S. Chattopadhyay, C.E. Whitehurst, F. Schwenk, and J. Chen Biochemical and functional analyses of chromatin changes at the TCR-beta gene locus during CD4-CD8- to CD4+CD8+ thymocyte differentiation J Immunol 160 1998 1256 1267
    • (1998) J Immunol , vol.160 , pp. 1256-1267
    • Chattopadhyay, S.1    Whitehurst, C.E.2    Schwenk, F.3    Chen, J.4
  • 70
    • 0032441260 scopus 로고    scopus 로고
    • Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: Role of receptor-associated chains and locus accessibility
    • S.K. Durum, S. Candeias, H. Nakajima, W.J. Leonard, A.M. Baird, and L.J. Berg Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility J Exp Med 188 1998 2233 2241
    • (1998) J Exp Med , vol.188 , pp. 2233-2241
    • Durum, S.K.1    Candeias, S.2    Nakajima, H.3    Leonard, W.J.4    Baird, A.M.5    Berg, L.J.6
  • 71
    • 0029797879 scopus 로고    scopus 로고
    • Transcription and demethylation of TCR beta gene initiate prior to the gene rearrangement in c-kit+ thymocytes with CD3 expression: Evidence of T cell commitment in the thymus
    • K. Hozumi, A. Kobori, T. Sato, T. Nishimura, and S. Habu Transcription and demethylation of TCR beta gene initiate prior to the gene rearrangement in c-kit+ thymocytes with CD3 expression: evidence of T cell commitment in the thymus Int Immunol 8 1996 1473 1481
    • (1996) Int Immunol , vol.8 , pp. 1473-1481
    • Hozumi, K.1    Kobori, A.2    Sato, T.3    Nishimura, T.4    Habu, S.5
  • 72
    • 0023872965 scopus 로고
    • Methylation patterns of the T cell receptor beta-chain gene in T cells, large granular lymphocytes, B cells, and monocytes
    • S. Sakamoto, J.R. Ortaldo, and H.A. Young Methylation patterns of the T cell receptor beta-chain gene in T cells, large granular lymphocytes, B cells, and monocytes J Immunol 140 1988 654 660
    • (1988) J Immunol , vol.140 , pp. 654-660
    • Sakamoto, S.1    Ortaldo, J.R.2    Young, H.A.3
  • 73
    • 0037625160 scopus 로고    scopus 로고
    • Gene segment selection in V(D)J recombination: Accessibility and beyond
    • M.S. Krangel Gene segment selection in V(D)J recombination: accessibility and beyond Nat Immunol 4 2003 624 630
    • (2003) Nat Immunol , vol.4 , pp. 624-630
    • Krangel, M.S.1
  • 74
    • 0041429637 scopus 로고    scopus 로고
    • Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development
    • T.H. Chi, M. Wan, P.P. Lee, K. Akashi, D. Metzger, and P. Chambon Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development Immunity 19 2003 169 182
    • (2003) Immunity , vol.19 , pp. 169-182
    • Chi, T.H.1    Wan, M.2    Lee, P.P.3    Akashi, K.4    Metzger, D.5    Chambon, P.6
  • 76
    • 0035575988 scopus 로고    scopus 로고
    • Cutting edge: Histone acetylation and recombination at the TCR gamma locus follows IL-7 induction
    • J. Huang, S.K. Durum, and K. Muegge Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction J Immunol 167 2001 6073 6077
    • (2001) J Immunol , vol.167 , pp. 6073-6077
    • Huang, J.1    Durum, S.K.2    Muegge, K.3
  • 77
    • 0034695539 scopus 로고    scopus 로고
    • Control of organ-specific demethylation by an element of the T-cell receptor-alpha locus control region
    • B. Santoso, B.D. Ortiz, and A. Winoto Control of organ-specific demethylation by an element of the T-cell receptor-alpha locus control region J Biol Chem 275 2000 1952 1958
    • (2000) J Biol Chem , vol.275 , pp. 1952-1958
    • Santoso, B.1    Ortiz, B.D.2    Winoto, A.3
  • 79
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • I. Taniuchi, M. Osato, T. Egawa, M.J. Sunshine, S.C. Bae, and T. Komori Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development Cell 111 2002 621 633
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6
  • 81
    • 2942520116 scopus 로고    scopus 로고
    • The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development
    • C.J. Williams, T. Naito, P.G. Arco, J.R. Seavitt, S.M. Cashman, and B. De Souza The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development Immunity 20 2004 719 733
    • (2004) Immunity , vol.20 , pp. 719-733
    • Williams, C.J.1    Naito, T.2    Arco, P.G.3    Seavitt, J.R.4    Cashman, S.M.5    De Souza, B.6
  • 82
    • 0037062922 scopus 로고    scopus 로고
    • Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
    • T.H. Chi, M. Wan, K. Zhao, I. Taniuchi, L. Chen, and D.R. Littman Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes Nature 418 2002 195 199
    • (2002) Nature , vol.418 , pp. 195-199
    • Chi, T.H.1    Wan, M.2    Zhao, K.3    Taniuchi, I.4    Chen, L.5    Littman, D.R.6
  • 83
    • 2942579099 scopus 로고    scopus 로고
    • Epigenetic gene silencing by Runx proteins
    • I. Taniuchi, and D.R. Littman Epigenetic gene silencing by Runx proteins Oncogene 23 2004 4341 4345
    • (2004) Oncogene , vol.23 , pp. 4341-4345
    • Taniuchi, I.1    Littman, D.R.2
  • 85
    • 0036885036 scopus 로고    scopus 로고
    • Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation
    • D. Kioussis, and W. Ellmeier Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation Nat Rev Immunol 2 2002 909 919
    • (2002) Nat Rev Immunol , vol.2 , pp. 909-919
    • Kioussis, D.1    Ellmeier, W.2
  • 86
    • 2442688211 scopus 로고    scopus 로고
    • The CD4/CD8 lineage choice: New insights into epigenetic regulation during T cell development
    • I. Taniuchi, W. Ellmeier, and D.R. Littman The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development Adv Immunol 83 2004 55 89
    • (2004) Adv Immunol , vol.83 , pp. 55-89
    • Taniuchi, I.1    Ellmeier, W.2    Littman, D.R.3
  • 87
    • 0024270410 scopus 로고
    • Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors
    • A.M. Carbone, P. Marrack, and J.W. Kappler Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors Science 242 1988 1174 1176
    • (1988) Science , vol.242 , pp. 1174-1176
    • Carbone, A.M.1    Marrack, P.2    Kappler, J.W.3
  • 88
    • 0025186696 scopus 로고
    • CD4-CD8- thymocytes that express the T cell receptor may have previously expressed CD8
    • L. Wu, M. Pearse, M. Egerton, H. Petrie, and R. Scollay CD4-CD8- thymocytes that express the T cell receptor may have previously expressed CD8 Int Immunol 2 1990 51 56
    • (1990) Int Immunol , vol.2 , pp. 51-56
    • Wu, L.1    Pearse, M.2    Egerton, M.3    Petrie, H.4    Scollay, R.5
  • 89
    • 0033553620 scopus 로고    scopus 로고
    • Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death
    • G.A. Pestano, Y. Zhou, L.A. Trimble, J. Daley, G.F. Weber, and H. Cantor Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death Science 284 1999 1187 1191
    • (1999) Science , vol.284 , pp. 1187-1191
    • Pestano, G.A.1    Zhou, Y.2    Trimble, L.A.3    Daley, J.4    Weber, G.F.5    Cantor, H.6
  • 90
  • 92
    • 0021237183 scopus 로고
    • The use of 5-azacytidine to establish constitutive interleukin 2-producing clones of the EL4 thymoma
    • Z.K. Ballas The use of 5-azacytidine to establish constitutive interleukin 2-producing clones of the EL4 thymoma J Immunol 133 1984 7 9
    • (1984) J Immunol , vol.133 , pp. 7-9
    • Ballas, Z.K.1
  • 93
    • 0032526641 scopus 로고    scopus 로고
    • Chromatin remodeling of the interleukin-2 gene: Distinct alterations in the proximal versus distal enhancer regions
    • S.B. Ward, G. Hernandez-Hoyos, F. Chen, M. Waterman, R. Reeves, and E.V. Rothenberg Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions Nucleic Acids Res 26 1998 2923 2934
    • (1998) Nucleic Acids Res , vol.26 , pp. 2923-2934
    • Ward, S.B.1    Hernandez-Hoyos, G.2    Chen, F.3    Waterman, M.4    Reeves, R.5    Rothenberg, E.V.6
  • 95
    • 0032143421 scopus 로고    scopus 로고
    • Mice with a fluorescent marker for interleukin 2 gene activation
    • M. Naramura, R.J. Hu, and H. Gu Mice with a fluorescent marker for interleukin 2 gene activation Immunity 9 1998 209 216
    • (1998) Immunity , vol.9 , pp. 209-216
    • Naramura, M.1    Hu, R.J.2    Gu, H.3
  • 97
    • 0032482996 scopus 로고    scopus 로고
    • Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation
    • A.V. Gett, and P.D. Hodgkin Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation Proc Natl Acad Sci USA 95 1998 9488 9493
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9488-9493
    • Gett, A.V.1    Hodgkin, P.D.2
  • 98
    • 0344806280 scopus 로고    scopus 로고
    • Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression
    • A. Richter, M. Lohning, and A. Radbruch Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression J Exp Med 190 1999 1439 1450
    • (1999) J Exp Med , vol.190 , pp. 1439-1450
    • Richter, A.1    Lohning, M.2    Radbruch, A.3
  • 99
    • 4644231710 scopus 로고    scopus 로고
    • DNA methylation is a nonredundant repressor of the Th2 effector program
    • K.W. Makar, and C.B. Wilson DNA methylation is a nonredundant repressor of the Th2 effector program J Immunol 173 2004 4402 4406
    • (2004) J Immunol , vol.173 , pp. 4402-4406
    • Makar, K.W.1    Wilson, C.B.2
  • 100
    • 0022389048 scopus 로고
    • 5-Azacytidine treatment of a murine cytotoxic T cell line alters interferon-gamma gene induction by interleukin 2
    • W.L. Farrar, F.W. Ruscetti, and H.A. Young 5-Azacytidine treatment of a murine cytotoxic T cell line alters interferon-gamma gene induction by interleukin 2 J Immunol 135 1985 1551 1554
    • (1985) J Immunol , vol.135 , pp. 1551-1554
    • Farrar, W.L.1    Ruscetti, F.W.2    Young, H.A.3
  • 101
    • 0027945516 scopus 로고
    • Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene
    • H.A. Young, P. Ghosh, J. Ye, J. Lederer, A. Lichtman, and J.R. Gerard Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene J Immunol 153 1994 3603 3610
    • (1994) J Immunol , vol.153 , pp. 3603-3610
    • Young, H.A.1    Ghosh, P.2    Ye, J.3    Lederer, J.4    Lichtman, A.5    Gerard, J.R.6
  • 102
    • 0028987326 scopus 로고
    • Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells
    • A.J. Melvin, M.E. McGurn, S.J. Bort, C. Gibson, and D.B. Lewis Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells Eur J Immunol 25 1995 426 430
    • (1995) Eur J Immunol , vol.25 , pp. 426-430
    • Melvin, A.J.1    McGurn, M.E.2    Bort, S.J.3    Gibson, C.4    Lewis, D.B.5
  • 103
    • 0032490674 scopus 로고    scopus 로고
    • Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: Regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells
    • D.R. Fitzpatrick, K.M. Shirley, L.E. McDonald, H. Bielefeldt-Ohmann, G.F. Kay, and A. Kelso Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells J Exp Med 188 1998 103 117
    • (1998) J Exp Med , vol.188 , pp. 103-117
    • Fitzpatrick, D.R.1    Shirley, K.M.2    McDonald, L.E.3    Bielefeldt-Ohmann, H.4    Kay, G.F.5    Kelso, A.6
  • 104
    • 0037087421 scopus 로고    scopus 로고
    • Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO-T cells
    • G.P. White, P.M. Watt, B.J. Holt, and P.G. Holt Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO-T cells J Immunol 168 2002 2820 2827
    • (2002) J Immunol , vol.168 , pp. 2820-2827
    • White, G.P.1    Watt, P.M.2    Holt, B.J.3    Holt, P.G.4
  • 105
    • 0031808712 scopus 로고    scopus 로고
    • IL-4 and prostaglandin E2 inhibit hypomethylation of the 5′ regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells
    • K. Katamura, T. Fukui, T. Kiyomasu, J. Iio, G. Tai, and H. Ueno IL-4 and prostaglandin E2 inhibit hypomethylation of the 5′ regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells Mol Immunol 35 1998 39 45
    • (1998) Mol Immunol , vol.35 , pp. 39-45
    • Katamura, K.1    Fukui, T.2    Kiyomasu, T.3    Iio, J.4    Tai, G.5    Ueno, H.6
  • 106
    • 0033136308 scopus 로고    scopus 로고
    • Cutting edge: Stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44highCD8+ T lymphocytes
    • D.R. Fitzpatrick, K.M. Shirley, and A. Kelso Cutting edge: stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44highCD8+ T lymphocytes J Immunol 162 1999 5053 5057
    • (1999) J Immunol , vol.162 , pp. 5053-5057
    • Fitzpatrick, D.R.1    Shirley, K.M.2    Kelso, A.3
  • 107
    • 0031811880 scopus 로고    scopus 로고
    • Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production
    • J.A. Mikovits, H.A. Young, P. Vertino, J.P. Issa, P.M. Pitha, and S. Turcoski-Corrales Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production Mol Cell Biol 18 1998 5166 5177
    • (1998) Mol Cell Biol , vol.18 , pp. 5166-5177
    • Mikovits, J.A.1    Young, H.A.2    Vertino, P.3    Issa, J.P.4    Pitha, P.M.5    Turcoski-Corrales, S.6
  • 108
    • 0036345455 scopus 로고    scopus 로고
    • Gene silencing quantitatively controls the function of a developmental trans-activator
    • A.S. Hutchins, A.C. Mullen, H.W. Lee, K.J. Sykes, F.A. High, and B.D. Hendrich Gene silencing quantitatively controls the function of a developmental trans-activator Mol Cell 10 2002 81 91
    • (2002) Mol Cell , vol.10 , pp. 81-91
    • Hutchins, A.S.1    Mullen, A.C.2    Lee, H.W.3    Sykes, K.J.4    High, F.A.5    Hendrich, B.D.6
  • 109
    • 0031035635 scopus 로고    scopus 로고
    • Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells
    • T.M. Aune, L.A. Penix, M.R. Rincon, and R.A. Flavell Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells Mol Cell Biol 17 1997 199 208
    • (1997) Mol Cell Biol , vol.17 , pp. 199-208
    • Aune, T.M.1    Penix, L.A.2    Rincon, M.R.3    Flavell, R.A.4
  • 110
    • 0025072964 scopus 로고
    • A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytes
    • J.C. Chrivia, T. Wedrychowicz, H.A. Young, and K.J. Hardy A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytes J Exp Med 172 1990 661 664
    • (1990) J Exp Med , vol.172 , pp. 661-664
    • Chrivia, J.C.1    Wedrychowicz, T.2    Young, H.A.3    Hardy, K.J.4
  • 111
    • 0029732843 scopus 로고    scopus 로고
    • The proximal regulatory element of the interferon-gamma promoter mediates selective expression in T cells
    • L.A. Penix, M.T. Sweetser, W.M. Weaver, J.P. Hoeffler, T.K. Kerppola, and C.B. Wilson The proximal regulatory element of the interferon-gamma promoter mediates selective expression in T cells J Biol Chem 271 1996 31964 31972
    • (1996) J Biol Chem , vol.271 , pp. 31964-31972
    • Penix, L.A.1    Sweetser, M.T.2    Weaver, W.M.3    Hoeffler, J.P.4    Kerppola, T.K.5    Wilson, C.B.6
  • 112
    • 0023110024 scopus 로고
    • Molecular events involved in regulating human interferon-gamma gene expression during T cell activation
    • K.J. Hardy, B. Manger, M. Newton, and J.D. Stobo Molecular events involved in regulating human interferon-gamma gene expression during T cell activation J Immunol 138 1987 2353 2358
    • (1987) J Immunol , vol.138 , pp. 2353-2358
    • Hardy, K.J.1    Manger, B.2    Newton, M.3    Stobo, J.D.4
  • 113
    • 0037114123 scopus 로고    scopus 로고
    • Cutting edge: Distal regulatory elements are required to achieve selective expression of IFN-gamma in Th1/Tc1 effector cells
    • M. Soutto, W. Zhou, and T.M. Aune Cutting edge: distal regulatory elements are required to achieve selective expression of IFN-gamma in Th1/Tc1 effector cells J Immunol 169 2002 6664 6667
    • (2002) J Immunol , vol.169 , pp. 6664-6667
    • Soutto, M.1    Zhou, W.2    Aune, T.M.3
  • 114
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • S. Agarwal, and A. Rao Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation Immunity 9 1998 765 775
    • (1998) Immunity , vol.9 , pp. 765-775
    • Agarwal, S.1    Rao, A.2
  • 115
    • 0035070195 scopus 로고    scopus 로고
    • Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
    • J.L. Grogan, M. Mohrs, B. Harmon, D.A. Lacy, J.W. Sedat, and R.M. Locksley Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets Immunity 14 2001 205 215
    • (2001) Immunity , vol.14 , pp. 205-215
    • Grogan, J.L.1    Mohrs, M.2    Harmon, B.3    Lacy, D.A.4    Sedat, J.W.5    Locksley, R.M.6
  • 116
    • 1042278131 scopus 로고    scopus 로고
    • A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison
    • D.U. Lee, O. Avni, L. Chen, and A. Rao A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison J Biol Chem 279 2004 4802 4810
    • (2004) J Biol Chem , vol.279 , pp. 4802-4810
    • Lee, D.U.1    Avni, O.2    Chen, L.3    Rao, A.4
  • 117
    • 0036305450 scopus 로고    scopus 로고
    • T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
    • O. Avni, D. Lee, F. Macian, S.J. Szabo, L.H. Glimcher, and A. Rao T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes Nat Immunol 3 2002 643 651
    • (2002) Nat Immunol , vol.3 , pp. 643-651
    • Avni, O.1    Lee, D.2    MacIan, F.3    Szabo, S.J.4    Glimcher, L.H.5    Rao, A.6
  • 118
    • 14244258294 scopus 로고    scopus 로고
    • A distal region in the IFN-gamma gene is a site of epigenetic remodeling and transcriptional regulation by IL-2
    • J.H. Bream, D.L. Hodge, R. Gonsky, R. Spolski, W.J. Leonard, and S. Krebs A distal region in the IFN-gamma gene is a site of epigenetic remodeling and transcriptional regulation by IL-2 J Biol Chem 101 2004 12622 12627
    • (2004) J Biol Chem , vol.101 , pp. 12622-12627
    • Bream, J.H.1    Hodge, D.L.2    Gonsky, R.3    Spolski, R.4    Leonard, W.J.5    Krebs, S.6
  • 119
    • 0037100265 scopus 로고    scopus 로고
    • Cutting edge: Changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation
    • P.E. Fields, S.T. Kim, and R.A. Flavell Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation J Immunol 169 2002 647 650
    • (2002) J Immunol , vol.169 , pp. 647-650
    • Fields, P.E.1    Kim, S.T.2    Flavell, R.A.3
  • 120
    • 0037236203 scopus 로고    scopus 로고
    • Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes
    • M. Messi, I. Giacchetto, K. Nagata, A. Lanzavecchia, G. Natoli, and F. Sallusto Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes Nat Immunol 4 2003 78 86
    • (2003) Nat Immunol , vol.4 , pp. 78-86
    • Messi, M.1    Giacchetto, I.2    Nagata, K.3    Lanzavecchia, A.4    Natoli, G.5    Sallusto, F.6
  • 122
    • 1442281449 scopus 로고    scopus 로고
    • Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation
    • W. Zhou, S. Chang, and T.M. Aune Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation Proc Natl Acad Sci USA 101 2004 2440 2445
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2440-2445
    • Zhou, W.1    Chang, S.2    Aune, T.M.3
  • 124
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
    • S.J. Szabo, B.M. Sullivan, C. Stemmann, A.R. Satoskar, B.P. Sleckman, and L.H. Glimcher Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells Science 295 2002 338 342
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 125
    • 0026467244 scopus 로고
    • A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer
    • G. Henkel, D.L. Weiss, R. McCoy, T. Deloughery, D. Tara, and M.A. Brown A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer J Immunol 149 1992 3239 3246
    • (1992) J Immunol , vol.149 , pp. 3239-3246
    • Henkel, G.1    Weiss, D.L.2    McCoy, R.3    Deloughery, T.4    Tara, D.5    Brown, M.A.6
  • 126
    • 0345019804 scopus 로고    scopus 로고
    • Long-range transcriptional regulation of cytokine gene expression
    • S. Agarwal, and A. Rao Long-range transcriptional regulation of cytokine gene expression Curr Opin Immunol 10 1998 345 352
    • (1998) Curr Opin Immunol , vol.10 , pp. 345-352
    • Agarwal, S.1    Rao, A.2
  • 127
    • 0032575727 scopus 로고    scopus 로고
    • Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells
    • M. Bix, and R.M. Locksley Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells Science 281 1998 1352 1354
    • (1998) Science , vol.281 , pp. 1352-1354
    • Bix, M.1    Locksley, R.M.2
  • 128
    • 0032142799 scopus 로고    scopus 로고
    • Regulation of IL-4 expression by activation of individual alleles
    • I. Riviere, M.J. Sunshine, and D.R. Littman Regulation of IL-4 expression by activation of individual alleles Immunity 9 1998 217 228
    • (1998) Immunity , vol.9 , pp. 217-228
    • Riviere, I.1    Sunshine, M.J.2    Littman, D.R.3
  • 129
    • 0034665338 scopus 로고    scopus 로고
    • Coordinate regulation of the IL-4, IL-13, and IL-5 cytokine cluster in Th2 clones revealed by allelic expression patterns
    • B.L. Kelly, and R.M. Locksley Coordinate regulation of the IL-4, IL-13, and IL-5 cytokine cluster in Th2 clones revealed by allelic expression patterns J Immunol 165 2000 2982 2986
    • (2000) J Immunol , vol.165 , pp. 2982-2986
    • Kelly, B.L.1    Locksley, R.M.2
  • 130
    • 0034616398 scopus 로고    scopus 로고
    • Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons
    • G.G. Loots, R.M. Locksley, C.M. Blankespoor, Z.E. Wang, W. Miller, and E.M. Rubin Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons Science 288 2000 136 140
    • (2000) Science , vol.288 , pp. 136-140
    • Loots, G.G.1    Locksley, R.M.2    Blankespoor, C.M.3    Wang, Z.E.4    Miller, W.5    Rubin, E.M.6
  • 132
    • 0037963472 scopus 로고    scopus 로고
    • Regulation of the Th2 cytokine locus by a locus control region
    • G.R. Lee, P.E. Fields, T.J. Griffin, and R.A. Flavell Regulation of the Th2 cytokine locus by a locus control region Immunity 19 2003 145 153
    • (2003) Immunity , vol.19 , pp. 145-153
    • Lee, G.R.1    Fields, P.E.2    Griffin, T.J.3    Flavell, R.A.4
  • 133
    • 0035984591 scopus 로고    scopus 로고
    • A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
    • D.C. Solymar, S. Agarwal, C.H. Bassing, F.W. Alt, and A. Rao A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells Immunity 17 2002 41 50
    • (2002) Immunity , vol.17 , pp. 41-50
    • Solymar, D.C.1    Agarwal, S.2    Bassing, C.H.3    Alt, F.W.4    Rao, A.5
  • 134
    • 5444237577 scopus 로고    scopus 로고
    • Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
    • C.G. Spilianakis, and R.A. Flavell Long-range intrachromosomal interactions in the T helper type 2 cytokine locus Nat Immunol 5 2004 1017 1027
    • (2004) Nat Immunol , vol.5 , pp. 1017-1027
    • Spilianakis, C.G.1    Flavell, R.A.2
  • 135
    • 0036667345 scopus 로고    scopus 로고
    • In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
    • L. Guo, J. Hu-Li, J. Zhu, C.J. Watson, M.J. Difilippantonio, and C. Pannetier In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production Proc Natl Acad Sci USA 99 2002 10623 10628
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10623-10628
    • Guo, L.1    Hu-Li, J.2    Zhu, J.3    Watson, C.J.4    Difilippantonio, M.J.5    Pannetier, C.6
  • 136
    • 0036279221 scopus 로고    scopus 로고
    • Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
    • D.U. Lee, S. Agarwal, and A. Rao Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene Immunity 16 2002 649 660
    • (2002) Immunity , vol.16 , pp. 649-660
    • Lee, D.U.1    Agarwal, S.2    Rao, A.3
  • 137
    • 0037103140 scopus 로고    scopus 로고
    • DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation
    • S. Santangelo, D.J. Cousins, N.E. Winkelmann, and D.Z. Staynov DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation J Immunol 169 2002 1893 1903
    • (2002) J Immunol , vol.169 , pp. 1893-1903
    • Santangelo, S.1    Cousins, D.J.2    Winkelmann, N.E.3    Staynov, D.Z.4
  • 138
    • 10344234192 scopus 로고    scopus 로고
    • Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
    • P.E. Fields, G.R. Lee, S.T. Kim, V.V. Bartsevich, and R.A. Flavell Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region Immunity 21 2004 865 876
    • (2004) Immunity , vol.21 , pp. 865-876
    • Fields, P.E.1    Lee, G.R.2    Kim, S.T.3    Bartsevich, V.V.4    Flavell, R.A.5
  • 139
    • 0037884760 scopus 로고    scopus 로고
    • DNA methylation and chromatin structure regulate T cell perforin gene expression
    • Q. Lu, A. Wu, D. Ray, C. Deng, J. Attwood, and S. Hanash DNA methylation and chromatin structure regulate T cell perforin gene expression J Immunol 170 2003 5124 5132
    • (2003) J Immunol , vol.170 , pp. 5124-5132
    • Lu, Q.1    Wu, A.2    Ray, D.3    Deng, C.4    Attwood, J.5    Hanash, S.6
  • 140
    • 0037454947 scopus 로고    scopus 로고
    • DNA methylation maintains allele-specific KIR gene expression in human natural killer cells
    • H.W. Chan, Z.B. Kurago, C.A. Stewart, M.J. Wilson, M.P. Martin, and B.E. Mace DNA methylation maintains allele-specific KIR gene expression in human natural killer cells J Exp Med 197 2003 245 255
    • (2003) J Exp Med , vol.197 , pp. 245-255
    • Chan, H.W.1    Kurago, Z.B.2    Stewart, C.A.3    Wilson, M.J.4    Martin, M.P.5    MacE, B.E.6
  • 141
    • 0037108489 scopus 로고    scopus 로고
    • Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells
    • S. Santourlidis, H.I. Trompeter, S. Weinhold, B. Eisermann, K.L. Meyer, and P. Wernet Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells J Immunol 169 2002 4253 4261
    • (2002) J Immunol , vol.169 , pp. 4253-4261
    • Santourlidis, S.1    Trompeter, H.I.2    Weinhold, S.3    Eisermann, B.4    Meyer, K.L.5    Wernet, P.6
  • 142
    • 0030175602 scopus 로고    scopus 로고
    • Type 1 and type 2: A fundamental dichotomy for all T-cell subsets
    • L.L. Carter, and R.W. Dutton Type 1 and type 2: a fundamental dichotomy for all T-cell subsets Curr Opin Immunol 8 1996 336 342
    • (1996) Curr Opin Immunol , vol.8 , pp. 336-342
    • Carter, L.L.1    Dutton, R.W.2
  • 143
    • 0031859293 scopus 로고    scopus 로고
    • In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines
    • A. Cerwenka, L.L. Carter, J.B. Reome, S.L. Swain, and R.W. Dutton In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines J Immunol 161 1998 97 105
    • (1998) J Immunol , vol.161 , pp. 97-105
    • Cerwenka, A.1    Carter, L.L.2    Reome, J.B.3    Swain, S.L.4    Dutton, R.W.5
  • 144
    • 0042432046 scopus 로고    scopus 로고
    • CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA
    • M. Omori, M. Yamashita, M. Inami, M. Ukai-Tadenuma, M. Kimura, and Y. Nigo CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA Immunity 19 2003 281 294
    • (2003) Immunity , vol.19 , pp. 281-294
    • Omori, M.1    Yamashita, M.2    Inami, M.3    Ukai-Tadenuma, M.4    Kimura, M.5    Nigo, Y.6
  • 145
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • D. Amsen, J.M. Blander, G.R. Lee, K. Tanigaki, T. Honjo, and R.A. Flavell Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell 117 2004 515 526
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1    Blander, J.M.2    Lee, G.R.3    Tanigaki, K.4    Honjo, T.5    Flavell, R.A.6
  • 146
    • 17944363602 scopus 로고    scopus 로고
    • Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene
    • M. Kimura, Y. Koseki, M. Yamashita, N. Watanabe, C. Shimizu, and T. Katsumoto Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene Immunity 15 2001 275 287
    • (2001) Immunity , vol.15 , pp. 275-287
    • Kimura, M.1    Koseki, Y.2    Yamashita, M.3    Watanabe, N.4    Shimizu, C.5    Katsumoto, T.6
  • 147
    • 0036284957 scopus 로고    scopus 로고
    • Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation
    • J. Zhu, L. Guo, B. Min, C.J. Watson, J. Hu-Li, and H.A. Young Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation Immunity 16 2002 733 744
    • (2002) Immunity , vol.16 , pp. 733-744
    • Zhu, J.1    Guo, L.2    Min, B.3    Watson, C.J.4    Hu-Li, J.5    Young, H.A.6
  • 148
    • 0035914950 scopus 로고    scopus 로고
    • Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells
    • M. Zhou, W. Ouyang, Q. Gong, S.G. Katz, J.M. White, and S.H. Orkin Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells J Exp Med 194 2001 1461 1471
    • (2001) J Exp Med , vol.194 , pp. 1461-1471
    • Zhou, M.1    Ouyang, W.2    Gong, Q.3    Katz, S.G.4    White, J.M.5    Orkin, S.H.6
  • 150
    • 0030927197 scopus 로고    scopus 로고
    • T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6
    • M. Kubo, J. Ransom, D. Webb, Y. Hashimoto, T. Tada, and T. Nakayama T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6 EMBO J 16 1997 4007 4020
    • (1997) EMBO J , vol.16 , pp. 4007-4020
    • Kubo, M.1    Ransom, J.2    Webb, D.3    Hashimoto, Y.4    Tada, T.5    Nakayama, T.6
  • 151
    • 3843060051 scopus 로고    scopus 로고
    • Chromatin landscape dynamics of the Il4-Il13 locus during T helper 1 and 2 development
    • A. Baguet, and M. Bix Chromatin landscape dynamics of the Il4-Il13 locus during T helper 1 and 2 development Proc Natl Acad Sci USA 101 2004 11410 11415
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11410-11415
    • Baguet, A.1    Bix, M.2
  • 152
    • 0025886982 scopus 로고
    • CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation
    • A. Bendelac, and R.H. Schwartz CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation Nature 353 1991 68 71
    • (1991) Nature , vol.353 , pp. 68-71
    • Bendelac, A.1    Schwartz, R.H.2
  • 153
    • 0036301997 scopus 로고    scopus 로고
    • Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
    • A.C. Mullen, A.S. Hutchins, F.A. High, H.W. Lee, K.J. Sykes, and L.A. Chodosh Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction Nat Immunol 3 2002 652 658
    • (2002) Nat Immunol , vol.3 , pp. 652-658
    • Mullen, A.C.1    Hutchins, A.S.2    High, F.A.3    Lee, H.W.4    Sykes, K.J.5    Chodosh, L.A.6
  • 154
    • 0029965236 scopus 로고    scopus 로고
    • Reversibility of T helper 1 and 2 populations is lost after long-term stimulation
    • E. Murphy, K. Shibuya, N. Hosken, P. Openshaw, V. Maino, and K. Davis Reversibility of T helper 1 and 2 populations is lost after long-term stimulation J Exp Med 183 1996 901 913
    • (1996) J Exp Med , vol.183 , pp. 901-913
    • Murphy, E.1    Shibuya, K.2    Hosken, N.3    Openshaw, P.4    Maino, V.5    Davis, K.6
  • 155
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • K.M. Murphy, and S.L. Reiner The lineage decisions of helper T cells Nat Rev Immunol 2 2002 933 944
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.