Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

Science

Volumn 295, Issue 5557, 2002, Pages 1079-1082

  Di Croce, Luciano ^a   Raker, Veronica A ^a   Corsaro, Massimo ^a   Fazi, Francesco ^a   Fanelli, Mirco ^a   Faretta, Mario ^a   Fuks, Francois ^a   Lo Coco, Francesco ^a   Kouzarides, Tony ^a   Nervi, Clara ^a   Minucci, Saverio ^a   Pelicci, Pier Giuseppe ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENES; MOLECULAR BIOLOGY; PROTEINS; TUMORS;

TARGET PROMOTERS;

GENETIC ENGINEERING;

CARCINOGEN; METHYLTRANSFERASE; TRANSCRIPTION FACTOR;

CANCER; DNA; GENE;

ARTICLE; CHROMATIN CONDENSATION; DEMETHYLATION; DINUCLEOTIDE REPEAT; DNA METHYLATION; GENE FREQUENCY; GENE OVEREXPRESSION; GENE TARGETING; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

AZACITIDINE; BINDING SITES; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CLONING, MOLECULAR; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EXONS; GENE EXPRESSION; GENE SILENCING; HISTONE DEACETYLASES; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MUTATION; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PROMOTER REGIONS (GENETICS); RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS; TRETINOIN; TUMOR CELLS, CULTURED; ZINC;

EID: 0038527642     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1065173     Document Type: Article

References (30)