DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals

Journal of Neuroscience

Volumn 21, Issue 3, 2001, Pages 788-797

  Fan, Guoping ^a   Beard, Caroline ^a   Chen, Richard Z ^a   Csankovszki, Györgyi ^a,b   Sun, Yi ^c   Siniaia, Marina ^b   Biniszkiewicz, Detlev ^a   Bates, Brian ^a,g   Lee, Peggy P ^d,h   Kühn, Ralf ^e,i   Trumpp, Andreas ^f,j   Poon, Chi Sang ^b   Wilson, Christopher B ^d   Jaenisch, Rudolf ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF COLOGNE   (Germany)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g PFIZER INC   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ Artemis Pharmaceuticals GmbH   (Germany)

^j SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

more..

Author keywords

Cre loxP system; Demethylation; DNA methylation; Dnmt1; Epigenetic mechanism; Gene regulation; Neural development; Respiration

Indexed keywords

DNA; DNA METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MUTANT; CELL SURVIVAL; CONTROLLED STUDY; DNA METHYLATION; EMBRYO DEVELOPMENT; GASTRULATION; GENE CONTROL; GENE DELETION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; MOUSE; NERVE CELL DIFFERENTIATION; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY DISTRESS;

EID: 0035109547     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-03-00788.2001     Document Type: Article

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