Distinct methylation of the interferon γ (IFN-γ) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: Regional IFN-γ promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells

Journal of Experimental Medicine

Volumn 188, Issue 1, 1998, Pages 103-117

  Fitzpatrick, David R ^a   Shirley, Kym M ^a   McDonald, Louise E ^a   Bielefeldt Ohmann, Helle ^b   Kay, Graham F ^a   Kelso, Anne ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

CD8+ T cell; DNA methylation; Gene expression; Interferon; Interleukin

Indexed keywords

CD8 ANTIGEN; DNA; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 3; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; FEMALE; GENE EXPRESSION REGULATION; HERITABILITY; INTERFERON PRODUCTION; MESSENGER RNA SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE HOMOLOGY; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD44; AZACITIDINE; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; CPG ISLANDS; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; INTERFERON TYPE II; INTERLEUKIN-3; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0032490674     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.1.103     Document Type: Article

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