MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase

Genes to Cells

Volumn 5, Issue 8, 2000, Pages 677-688

  Tatematsu, K I ^a   Yamazaki, T ^a   Ishikawa, F ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; HISTONE DEACETYLASE;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CELL CYCLE S PHASE; CHROMATIN; DNA METHYLATION; DNA REPLICATION; GENE EXPRESSION REGULATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN LOCALIZATION;

CHROMATIN; DIMERIZATION; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA REPLICATION; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; PRECIPITIN TESTS; PROTEIN BINDING; S PHASE; TWO-HYBRID SYSTEM TECHNIQUES;

VERTEBRATA;

EID: 0033883260     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2000.00359.x     Document Type: Article

References (43)

1. Concurrent replication and methylation at mammalian origins of replication
2. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency
3. Mammalian X-chromosome inactivation and the XIST gene
4. Genomic imprinting in mammals
5. MED1, a novel human methy-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1
6. Activation of mammalian DNA methyl-transferase by cleavage of a Zn binding regulatory domain
7. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
8. Methylation-induced repression - Belts, braces, and chromatin
9. Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
10. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
11. A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins
12. Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms
13. DNA methyltransferase Dnmt1 associates with histone deacetylase activity
14. Identification and characterization of a family of mammalian methyl-CpG binding proteins
15. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
16. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
17. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
18. Protein-PCNA interactions: A DNA-scanning mechanism?
19. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
20. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
21. Purification, sequence and cellular localization of a novel chromosomal protein that binds to methylated DNA
22. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
23. Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
24. Mapping of replicational sites in the eucaryotic cell nucleus
25. MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
26. Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
27. Transcriptional repression by the methy-CpG-binding protein MeCP2 involves a histone deacetylase complex
28. DNA methlyation and chromatin modification
29. Active repression of methylated genes by the chromosomal protein MBD1
30. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
31. Dynamic organization of DNA replication in mammalian cell nuclei: Spatial and temporally defined replication pf chromosome-specific α-satellite DNA sequence
32. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
33. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyl-transferases
34. DNA methylation and gene function
35. The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability
36. Trichostatin A causes selective loss of DNA methylation in Neurospora
37. Replication-dependent marking of DNA by PCNA fascilitates CAF-1-coupled inheritance of chromatin
38. Growth regulation of mouse DNA methyltransferase gene expression
39. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacerylation
40. A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase
41. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
42. Gene methylation patterns and expression
43. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation