메뉴 건너뛰기




Volumn 915, Issue 1, 2001, Pages 1-10

Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice

Author keywords

Hippocampal neurons; Knock in mice; Par 4; Presenilin 1

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CASPASE 3; CELL PROTEIN; GLUCOSE; PRESENILIN 1; PROTEIN PAR 4; UNCLASSIFIED DRUG;

EID: 0035812914     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02803-7     Document Type: Article
Times cited : (23)

References (88)
  • 3
    • 0032575687 scopus 로고    scopus 로고
    • Is apoptosis key in Alzheimer's disease?
    • (1998) Science , vol.281 , pp. 1303-1304
    • Barinaga, M.1
  • 6
    • 0034604340 scopus 로고    scopus 로고
    • Alzheimer's disease: Neurodevelopment converges with neurodegeneration
    • (2000) Cell , vol.102 , pp. 271-273
    • Bothwell, M.1    Giniger, E.2
  • 7
    • 0033152441 scopus 로고    scopus 로고
    • Presenilins, processing of beta-amyloid precursor protein, and Notch signaling
    • (1999) Neuron , vol.23 , pp. 201-204
    • Chan, Y.M.1    Jan, Y.N.2
  • 9
    • 0026659777 scopus 로고
    • Glucose deprivation elicits neurofibrillary tangle-like antigenic changes in hippocampal neurons: Prevention by NGF and bFGF
    • (1992) Exp. Neurol. , vol.117 , pp. 114-123
    • Cheng, B.1    Mattson, M.P.2
  • 13
    • 0034621823 scopus 로고    scopus 로고
    • Alzheimer's disease. Closing in on gamma-secretase
    • (2000) Nature , vol.405 , pp. 627-629
    • De Strooper, B.1
  • 23
    • 0032524319 scopus 로고    scopus 로고
    • Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis
    • (1998) J. Biol. Chem. , vol.273 , pp. 12341-12351
    • Guo, Q.1    Robinson, N.2    Mattson, M.P.3
  • 29
    • 0034714361 scopus 로고    scopus 로고
    • Par-4 induces cholinergic hypoactivity by suppressing ChAT protein synthesis and inhibiting NGF-inducibility of ChAT activity
    • (2000) Brain Res. , vol.874 , pp. 221-232
    • Guo, Q.1    Xie, J.2    Du, H.3
  • 30
    • 0030922421 scopus 로고    scopus 로고
    • Presenilins: Genes for life and death
    • (1997) Neuron , vol.18 , pp. 687-690
    • Haass, C.1
  • 34
    • 0034440140 scopus 로고    scopus 로고
    • A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events
    • (2000) Rev. Neurosci. , vol.11 , pp. 213-328
    • Heininger, K.1
  • 35
    • 0027195933 scopus 로고
    • Seeding 'one-dimensional crystallization' of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarrett, J.T.1    Lansbury, P.T.2
  • 37
    • 0026539331 scopus 로고
    • Alzheimer's disease: A cell biological perspective
    • (1992) Science , vol.256 , pp. 780-783
    • Kosik, K.S.1
  • 38
    • 0032559189 scopus 로고    scopus 로고
    • Presenilin interactions and Alzheimer's disease
    • (1998) Science , vol.279 , pp. 463-465
    • Kosik, K.S.1
  • 44
    • 0030761059 scopus 로고    scopus 로고
    • Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation
    • (1997) Cell , vol.90 , pp. 917-927
    • Li, J.1    Xu, M.2    Zhou, H.3    Ma, J.4    Potter, H.5
  • 47
    • 0030300114 scopus 로고    scopus 로고
    • Dissecting how presinilins function - And malfunction
    • (1996) Science , vol.274 , pp. 1838-1840
    • Marx, J.1
  • 48
    • 0034652369 scopus 로고    scopus 로고
    • Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis
    • (2000) J. Neurosci. , vol.20 , pp. 1358-1364
    • Mattson, M.P.1    Zhu, H.2    Yu, J.3    Kindy, M.S.4
  • 49
    • 0033230623 scopus 로고    scopus 로고
    • Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles
    • (1999) Neuron , vol.24 , pp. 521-529
    • Mesulam, M.M.1
  • 52
    • 0033695947 scopus 로고    scopus 로고
    • Presenilins, Alzheimer's disease, and capacitative calcium entry
    • (2000) Neuron , vol.27 , pp. 411-412
    • Putney, J.W.1
  • 57
    • 0034618556 scopus 로고    scopus 로고
    • Alzheimer's disease. A partner for presenilin
    • (2000) Nature , vol.407 , pp. 34-35
    • Schenk, D.1
  • 59
    • 0024314702 scopus 로고
    • Amyloid beta protein precursor and the pathogenesis of Alzheimer's disease
    • (1989) Cell , vol.58 , pp. 611-612
    • Selkoe, D.J.1
  • 60
    • 0025295036 scopus 로고
    • Deciphering Alzheimer's disease: The amyloid precursor protein yields new clues
    • (1990) Science , vol.248 , pp. 1058-1060
    • Selkoe, D.J.1
  • 61
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes, phenotypes, and treatments
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 62
    • 0033600274 scopus 로고    scopus 로고
    • Translating cell biology into therapeutic advances in Alzheimer's disease
    • (1999) Nature , vol.399 , pp. A23-A31
    • Selkoe, D.J.1
  • 66
    • 0034730295 scopus 로고    scopus 로고
    • Neuroscience. An accomplice for gamma-secretase brought into focus
    • (2000) Science , vol.289 , pp. 2296-2297
    • Sisodia, S.S.1
  • 68
    • 0033535508 scopus 로고    scopus 로고
    • Presenilin is required for activity and nuclear access of notch in Drosophila
    • (1999) Nature , vol.398 , pp. 522-525
    • Struhl, G.1    Greenwald, I.2
  • 73
    • 0033623415 scopus 로고    scopus 로고
    • Abeta-generating enzymes: Recent advances in beta- and gamma-secretase research
    • (2000) Neuron , vol.27 , pp. 419-422
    • Vassar, R.1    Citron, M.2
  • 82
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • (1996) Neuron , vol.16 , pp. 921-932
    • Yankner, B.A.1
  • 87
    • 0033581321 scopus 로고    scopus 로고
    • Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
    • (1999) Brain Res. , vol.842 , pp. 224-229
    • Zhu, H.1    Guo, Q.2    Mattson, M.P.3
  • 88
    • 0035844283 scopus 로고    scopus 로고
    • Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway
    • (2001) J. Biol. Chem. , vol.276 , pp. 16040-16044
    • Guo, Q.1    Xie, J.2    Chang, X.3    Du, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.