-
4
-
-
12644282563
-
On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15195-15202
-
-
Birnbaumer, L.1
Zhu, X.2
Jiang, M.3
Boulay, G.4
Peyton, M.5
Vannier, B.6
Brown, D.7
Platano, D.8
Sadeghi, H.9
Stefani, E.10
Birnbaumer, M.11
-
5
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-H.7
Kim, G.8
Seekins, S.9
Yager, D.10
-
6
-
-
0033592912
-
2+ entry
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14955-14960
-
-
Boulay, G.1
Brown, D.M.2
Qin, N.3
Jiang, M.4
Dietrich, A.5
Zhu, M.X.6
Chen, Z.7
Birnbaumer, M.8
Mikoshiba, K.9
Birnbaumer, L.10
-
7
-
-
0034737703
-
2+ entry pathway by store depletion in cultured hippocampal neurons
-
(2000)
FEBS Lett.
, vol.470
, pp. 269-272
-
-
Bouron, A.1
-
8
-
-
0032488995
-
The proteolytic fragments of the Alzheimer's disease-associated presenilin 1 form heterodimers and occur as a 100-150 kDa molecular mass complex
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3205-3211
-
-
Capell, A.1
Grunberg, J.2
Pesold, B.3
Diehlmann, A.4
Citron, M.5
Nixon, R.6
Beyreuther, K.7
Selkoe, D.J.8
Haass, C.9
-
9
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
(1996)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levsque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
-
11
-
-
0029812077
-
Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9223-9228
-
-
Cook, D.G.1
Sung, J.C.2
Golde, T.E.3
Felsenstein, K.M.4
Wojczk, B.S.5
Tanzi, R.E.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
Doms, R.W.9
-
13
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vandersticheles, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
14
-
-
0033535504
-
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Safig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
-
15
-
-
0030293854
-
Protein topology of presenilin 1
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.R.3
Slunt, H.H.4
Ratovitsky, T.5
Podlisny, M.6
Selkoe, D.J.7
Seeger, M.8
Gandy, S.E.9
Price, D.L.10
Sisodia, S.S.11
-
16
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
-
17
-
-
0032127927
-
Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 37-45
-
-
Etcheberrigaray, R.1
Hirashima, N.2
Nee, L.3
Prince, J.4
Govoni, S.5
Racchi, M.6
Tanzi, R.E.7
Alkon, D.L.8
-
20
-
-
0030891662
-
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide
-
(1996)
Neuroreport
, vol.8
, pp. 379-383
-
-
Guo, Q.1
Furukawa, K.2
Sopher, B.L.3
Pham, D.G.4
Xie, J.5
Robinson, N.6
Martin, G.M.7
Mattson, M.P.8
-
22
-
-
0026594980
-
Depletion of intracellular calcium stores activates a calcium current in mast cells
-
(1992)
Nature
, vol.355
, pp. 353-356
-
-
Hoth, M.1
Penner, R.2
-
23
-
-
0025195367
-
2+ entry by inositol phosphate - A possible mechanism
-
(1990)
FEBS Lett.
, vol.263
, pp. 5-9
-
-
Irvine, R.F.1
-
24
-
-
0028179578
-
2+-mobilization is altered in fibroblasts from patients with Alzheimer's disease
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 534-538
-
-
Ito, E.1
Oka, K.2
Etcheberrigaray, R.3
Nelson, T.4
McPhie, D.L.5
Tofel-Grehl, B.6
Gibson, G.E.7
Alkon, D.L.8
-
26
-
-
0030771534
-
Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I)
-
(1997)
J. Cell Biol.
, vol.139
, pp. 485-495
-
-
Janicki, S.1
Monteiro, M.J.2
-
28
-
-
0031020909
-
42 deposition in a transgenic mouse model of Alzheimer's disease
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1550-1555
-
-
Johnson-Wood, K.1
Lee, M.2
Motter, R.3
Hu, K.4
Gordon, G.5
Barbour, R.6
Khan, K.7
Gordon, M.8
Tan, H.9
Games, D.10
-
29
-
-
0033258544
-
Presenilin-1 mutations downregulate the signaling pathway of the unfolded-protein response
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
-
34
-
-
0032480821
-
3 receptors and store-operated Htrp3 channels
-
(1998)
Nature
, vol.396
, pp. 478-482
-
-
Kiselyov, K.1
Xu, X.2
Mozhayeva, G.3
Kuo, T.4
Pessah, I.5
Mignery, G.6
Zhu, X.7
Birnbaumer, L.8
Muallem, S.9
-
36
-
-
13344282063
-
Alzheimer associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
(1996)
Nat. Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
Kim, T.-W.4
Moir, R.D.5
Merriam, D.E.6
Hollister, R.D.7
Hallmark, O.G.8
Mancini, R.9
Felsenstein, K.M.10
-
44
-
-
0025103909
-
SKandF 96365, a novel inhibitor of receptor-mediated calcium entry
-
(1990)
Biochem. J.
, vol.271
, pp. 515-522
-
-
Merritt, J.E.1
Armstrong, W.P.2
Benham, C.D.3
Hallam, T.J.4
Jacob, R.5
Jaxa-Chamiec, A.6
Leigh, B.K.7
McCarthy, S.A.8
Moores, K.E.9
Rink, T.J.10
-
46
-
-
0000138540
-
Effects of PS1 deficiency on membrane protein trafficking in neurons
-
(1998)
Neuron
, vol.21
, pp. 1213-1221
-
-
Naruse, S.1
Thinakaran, G.2
Luo, J.-J.3
Kusiak, J.W.4
Tomita, T.5
Iwatsubo, T.6
Qian, X.7
Ginty, D.D.8
Price, D.L.9
Borchelt, D.R.10
-
48
-
-
18544411933
-
-
(1998)
J. Neurochem.
, vol.71
, pp. 313-322
-
-
Oyama, F.1
Sawamura, N.2
Kobayashi, K.3
Morishima-Kawashima, M.4
Kuramochi, T.5
Ito, M.6
Tomita, T.7
Maruyama, K.8
Saido, T.C.9
Iwatsubo, T.10
-
49
-
-
0034640292
-
Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14440-14445
-
-
Pack-Chung, E.1
Meyers, M.B.2
Pettingell, W.P.3
Moir, R.D.4
Erownawell, A.M.5
Cheng, I.6
Tanzi, R.E.7
Kim, T.-W.8
-
54
-
-
0033215397
-
'Kissin' cousins': Intimate plasma membrane-ER interactions underlies capacitative calcium entry
-
(1999)
Cell
, vol.99
, pp. 5-8
-
-
Putney J.W., Jr.1
-
58
-
-
16044373524
-
Aβ42(43) is increased in vivo by the PS1/2 and APP mutations linked to familial Alzheimer's disease
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.M.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
-
59
-
-
12644290265
-
Evidence for phosphorylation and oligomeric assembly of presenilin 1
-
(1997)
Proc. Nath Acad. Sci. USA
, vol.94
, pp. 5090-5094
-
-
Seeger, M.1
Nordstedt, C.2
Petanceska, S.3
Kovacs, D.M.4
Gouras, G.K.5
Hahne, S.6
Fraser, P.7
Levesque, L.8
St. Czernik, A.J.9
George-Hyslop, P.10
-
60
-
-
0032211830
-
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
61
-
-
0033966452
-
Notch and presenilins in vertebrates and invertebrates: Implications for neuronal development and degeneration
-
(2000)
Curr. Opin. Neurobiol.
, vol.10
, pp. 50-57
-
-
Selkoe, D.J.1
-
64
-
-
0033214070
-
A loss of function mutation of presenilin-2 interferes with amyloid β-peptide production and Notch signaling
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28669-28673
-
-
Steiner, H.1
Duff, K.2
Capell, A.3
Romig, H.4
Grim, M.G.5
Lincoln, S.6
Hardy, J.7
Yu, X.8
Picciano, M.9
Fechteler, K.10
-
66
-
-
0002603304
-
The molecular genetics of Alzheimer's disease
-
Scientific American Molecular Neurology, J.B. Martin, ed. New York, NY: Scientific American Press
-
(1998)
, pp. 55-75
-
-
Tanzi, R.E.1
-
67
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.2
Lee, M.3
Slunt, H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
-
68
-
-
0030667426
-
Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28415-28422
-
-
Thinakaran, G.1
Harris, C.L.2
Ratovitski, T.3
Davenport, F.4
Slunt, H.H.5
Price, D.L.6
Borchelt, D.R.7
Sisodia, S.S.8
-
70
-
-
12644258498
-
The presenilin 2 mutations (N141l) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid protein ending at the 42nd (or 43rd) residue
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
-
71
-
-
0033573477
-
C terminus of presenilin 1 is required for overproduction of amyloidogenic Aβ42 through stabilization and endoproteolysis of presenilin
-
(1999)
J. Neurosci.
, vol.19
, pp. 10627-10634
-
-
Tomita, T.1
Takikawa, R.2
Koyama, A.3
Morohashi, Y.4
Takasugi, N.5
Saido, T.C.6
Maruyama, K.7
Iwatsubo, T.8
-
75
-
-
10544224542
-
PS2 participates in cellular apoptosis: Constitutive activity conferred by Alzheimer mutation
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
Ganjei, K.4
Lacana, E.5
Sunderland, T.6
Zhao, B.7
Kusiak, J.W.8
Wasco, W.9
D'Adamio, L.10
-
76
-
-
16944365745
-
Enhanced production and oligonerization of the 42-residue amyloid beta protein by Chinese hamster ovary cells stably expressing mutant presenilins
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7977-7982
-
-
Xia, W.1
Zhang, J.2
Kholodenko, D.3
Citron, M.4
Podlisney, M.B.5
Teplow, D.B.6
Haass, C.7
Seubert, P.8
Koo, E.H.9
Selkoe, D.J.10
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