Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid β-peptide: Involvement of calcium and oxyradicals

Journal of Neuroscience

Volumn 17, Issue 11, 1997, Pages 4212-4222

  Guo, Qing ^a   Sopher, Bryce L ^b   Furukawa, Katsutoshi ^a   Pham, Dao G ^b   Robinson, Nic ^a   Martin, George M ^b   Mattson, Mark P ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; antioxidant; bcl 2; dantrolene; endoplasmic reticulum; fura 2; nerve growth factor

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); AMYLOID BETA PROTEIN; ANTIOXIDANT; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; MEMBRANE PROTEIN; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; OXYGEN RADICAL; PROTEIN BCL 2;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ETIOLOGY; GENE MUTATION; NERVE CELL DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0030917601     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-11-04212.1997     Document Type: Article

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