Dietary restriction protects hippocampal neurons against the death- promoting action of a presenilin-1 mutation

Brain Research

Volumn 842, Issue 1, 1999, Pages 224-229

  Zhu, Haiyan ^a   Guo, Qing ^a   Mattson, Mark P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer; Apoptosis; Calorie restriction; Excitotoxicity; Hyroxynonenal; Kainate; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; KAINIC ACID; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; GENE MUTATION; HIPPOCAMPUS; LIPID PEROXIDATION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ALZHEIMER DISEASE; ANIMALS; BODY WEIGHT; CELL DEATH; DIET; EATING; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; LIPID PEROXIDATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; PRESENILIN-1;

EID: 0033581321     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01827-2     Document Type: Article

References (49)

1. Aksenova M.V., Aksenov M.Y., Carney J.M., Butterfield D.A. Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction. Mech. Ageing Dev. 100:1998;157-168.
2. Aly K.B., Pipkin J.L., Hinson W.G., Feuers R.J., Duffy P.H., Lyn-Cook L., Hart R.W. Chronic caloric restriction induces stress proteins in the hypothalamus of rats. Mech. Ageing Dev. 76:1994;11-23.
3. Begley J.G., Duan W., Duff K., Mattson M.P. Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. J. Neurochem. 72:1999;1030-1039.
4. Bowling A.C., Beal M.F. Bioenergetic and oxidative stress in neurodegenerative diseases. Life Sci. 56:1995;1151-1171.
5. Bruce-Keller A.J., Li Y.-J., Lovell M.A., Kraemer P.J., Gary D.S., Brown R.R., Markesbery W.R., Mattson M.P. 4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats. J. Neuropathol. Exp. Neurol. 57:1998;257-267.
6. Bruce-Keller A.J., Umberger G., McFall R., Mattson M.P. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol. 45:1999;8-15.
7. Duan W., Mattson M.P. Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res. 57:1999;195-206.
8. Dubey A., Forster M.J., Lal H., Sohal R.S. Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of mouse. Arch. Biochem. Biophys. 333:1996;189-197.
9. Duff K., Eckman C., Zehr C., Yu X., Prada C.M., Perez-Tur J., Hutton M., Buee L., Harigaya Y., Yager D., Morgan D., Gordon M.N., Holcomb L., Refolo L., Zenk B., Hardy J., Younkin S. Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713.
10. Ehrenfried J.A., Evers B.M., Chu K.U., Townsend C.M., Thompson J.C. Caloric restriction increases the expression of heat shock protein in the gut. Ann. Surg. 223:1996;592-597.
11. C.E Finch, T.E. Morgan, Food restriction and brain aging, in: M.P. Mattson, J.W. Geddes (Eds.), The Aging Brain, JAI Press, Adv. Cell Aging Gerontol. 2 (1997) 279-297.
12. Good P.F., Werner P., Hsu A., Olanow C.W., Perl D.P. Evidence of neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 149:1996;21-28.
13. Greenamyre J.T., Young A.B. Excitatory amino acids and alzheimer's disease. Neurobiol. Aging. 10:1989;593-602.
14. Guo Q., Furukawa K., Sopher B.L., Pham D.G., Xie J., Robinson N., Martin G.M., Mattson M.P. Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide. NeuroReport. 8:1996;379-383.
15. Guo Q., Sopher B.L., Pham D.G., Furukawa K., Robinson N., Martin G.M., Mattson M.P. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid β-peptide: involvement of calcium and oxyradicals. J. Neurosci. 17:1997;4212-4222.
16. Guo Q., Christakos S., Robinson N., Mattson M.P. Calbindin blocks the pro-apoptotic actions of mutant presenilin-1: reduced oxidative stress and preserved mitochondrial function. Proc. Natl. Acad. Sci. U.S.A. 95:1998;3227-3232.
17. Guo Q., Sebastian Q.L., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid β-peptide toxicity: central roles of superoxide production and caspase activation. J. Neurochem. 72:1999;1019-1029.
18. Guo Q., Fu W., Sopher B.L., Miller M.W., B Ware C., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knockin mice. Nat. Med. 5:1999;101-107.
19. Guo Q., Sebastian L., Sopher B.L., Miller M.W., Glazner G.W., Ware C.B., Martin G.M., Mattson M.P. Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a presenilin-1 mutation. Proc. Natl. Acad. Sci. U.S.A. 96:1999;4125-4130.
20. Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20:1997;154-159.
21. Harman D. Role of free radicals in aging and disease. Ann. N. Y. Acad. Sci. 673:1992;126-141.
22. Heydari A.R., You S., Takahashi R., Gutsmann A., Sarge K.D., Richardson A. Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Dev. Genet. 18:1996;114-124.
23. Idrobo F., Nandy K., Mostofsky D.I., Blatt L., Nandy L. Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex. Arch. Gerontol. Geriatr. 6:1987;355-362.
24. Ingram D.K., Weindruch R., Spangler E.L., Freeman J.R., Walford R.L. Dietary restriction benefits learning and motor performance of aged mice. J. Gerontol. 42:1987;78-81.
25. Keller J.N., Pang Z., Geddes J.W., Begley J.G., Germeyer A., Waeg G., Mattson M.P. Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem. 69:1997;273-284.
26. Lee J., Bruce-Keller A.J., Kruman U., Chan S., Mattson M.P. 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: involvement of stress proteins. J. Neurosci. Res. 57:1999;48-61.
27. Logroscino G., Marder K., Cote L., Tang M.X., Shea S., Mayeux R. Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Ann. Neurol. 39:1996;89-94.
28. Lovell M.A., Ehmann W.D., Mattson M.P., Markesbery W.R. Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiol. Aging. 18:1997;457-461.
29. Lowenstein D.H., Chan P., Miles M. The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity. Neuron. 7:1991;1053-1060.
30. Mark R.J., Lovell M.A., Markesbery W.R., Uchida K., Mattson M.P. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J. Neurochem. 68:1997;255-264.
31. Masliah E., Mallory M., Alford M., Tanaka S., Hansen L.A. Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease. J. Neuropathol. Exp. Neurol. 57:1998;1041-1052.
32. Mattson M.P., Barger S.W., Cheng B., Lieberburg I., Smith-Swintosky V.L., Rydel R.E. β-Amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease. Trends Neurosci. 16:1993;409-415.
33. i and neurotoxicity, and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65:1995;1740-1751.
34. Mattson M.P. Cellular actions of β-amyloid precursor protein, and its soluble and fibrillogenic peptide derivatives. Physiol. Rev. 77:1997;1081-1132.
35. Mattson M.P., Guo Q. The Presenilins. Neuroscientist. 5:1999;112-124.
36. Meyeux R., Costa R., Bell K., Merchant C., Tung M.X., Jacobs D. Reduced risk of Alzheimer's disease among individuals with low calorie intake. Neurology. 59:1999;S296-S297.
37. Morgan T.E., Rozovsky I., Goldsmith S.K., Stone D.J., Yoshida T., Finch C.E. Increased transcription of the astrocyte gene GFAP during middle age is attenuated by food restriction: implications for the role of oxidative stress. Free Radical Biol. Med. 23:1997;524-528.
38. Pitsikas N., Algeri S. Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction. Neurobiol. Aging. 13:1992;369-373.
39. Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T.D., Hardy J., Hutton M., Kukull W., Larson E., Levy-Lahad E., Viitanen M., Peskind E., Poorkaj P., Schellenberg G., Tanzi R., Wasco W., Lannfelt L., Selkoe D., Younkin S. The amyloid β protein deposited in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:1996;864-870.
40. Smith M.A., Harris P.L.R., Sayre L.M., Beckman J.S., Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 17:1997;2653-2657.
41. Sohal R.S., Ku H.H., Agarwal S., Forster M.J., Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech. Ageing Dev. 74:1994;121-133.
42. Sohal R.S., Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 273:1996;59-63.
43. Stewart J., Mitchell J., Kalant N. The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes. Neurobiol. Aging. 10:1989;669-675.
44. Tan D.X., Manchester L.C., Reiter R.J., Qi W., Kim S.J., El-Sokkary G.H. Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in mice. J. Neurosci. Res. 54:1998;382-389.
45. Y. Ueda, H. Yokoyama, R. Niwa, R. Konaka, H. Ohya-Nishiguchi, H. Kamada, Generation of lipid radicals in the hippocampal extracellular space during kainic acid-induced seizures in rats, Epilepsy Res. (1997) 329-333.
46. Weindruch R.L., Walford S., Fligiel S., Guthrie D D. The retardation of aging by dietary restriction: longevity, immunity and lifetime energy intake. J. Nutr. 116:1986;641-654.
47. Waeg G., Dimsity G., Esterbauer H. Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins. Free Radical Res. 25:1996;149-159.
48. Yu Z.F., Luo H., Fu W., Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155:1999;302-314.
49. Z.F. Yu, M.P. Mattson, Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome, J. Neurosci. Res. (1999), in press.