Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis

Journal of Neuroscience

Volumn 20, Issue 4, 2000, Pages 1358-1364

  Mattson, Mark P ^a,c,e   Zhu, Haiyan ^a   Yu, Jin ^a,b,d   Kindy, Mark S ^a,b,d  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d LEXINGTON VA MEDICAL CENTER   (United States)

^e GRC   (United States)

Author keywords

Alzheimer's disease; Dantrolene; Endoplasmic reticulum; Knock in; Stroke; Transgenic

Indexed keywords

CALCIUM ION; DANTROLENE; GLUCOSE; INOSITOL PHOSPHATE; PRESENILIN 1; RYANODINE RECEPTOR;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENDOPLASMIC RETICULUM; GENE MUTATION; HYPOXIA; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; STROKE; TRANSGENIC MOUSE;

EID: 0034652369     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-04-01358.2000     Document Type: Article

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