In search of γ-secretase: Presenilin at the cutting edge

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 11, 2000, Pages 5690-5692

  Selkoe, D J ^a   Wolfe, M S ^a  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; 3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 2 HYDROXY 1 PROPANESULFONIC ACID; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; NOTCH RECEPTOR; PRESENILIN 1;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; MISSENSE MUTATION; NOTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SIGNAL TRANSDUCTION; SOLUBILIZATION; STRUCTURE ACTIVITY RELATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CHOLIC ACIDS; DETERGENTS; DIMERIZATION; ENDOPEPTIDASES; ENDORIBONUCLEASES; HELA CELLS; HUMANS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; PRESENILIN-1; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, NOTCH; SUBSTRATE SPECIFICITY;

EID: 0034705204     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.11.5690     Document Type: Note

References (35)