E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles

Human Mutation

Volumn 10, Issue 3, 1997, Pages 186-195

  Lendon, Corinne L ^a   Martinez, Alonso ^a,b   Behrens, Isabel Maria ^a   Kosik, Kenneth S ^c   Madrigal, Lucia ^b   Norton, Joanne ^a   Neuman, Rosalind ^a   Myers, Amanda ^a   Busfield, Frances ^a   Wragg, Michelle ^a   Arcos, Mauricio ^b   Viana, Juan Carlos Arango ^b   Ossa, Jorge ^b   Ruiz, Andres ^b   Goate, Alison M ^a   Lopera, Francisco ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Mutation; Presenilin 1

Indexed keywords

ALANINE; APOLIPOPROTEIN E; DNA; GLUTAMIC ACID; PRESENILIN 1; PROTEIN;

ALLELE; ALZHEIMER DISEASE; ARTICLE; CHROMOSOME 14; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DNA SEQUENCE; GENE; GENE MUTATION; GENETIC LINKAGE; GENOTYPE; HAPLOTYPE; HEAD INJURY; HUMAN; NUCLEIC ACID BASE SUBSTITUTION; ONSET AGE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR;

ADULT; AGE OF ONSET; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; DNA; DNA MUTATIONAL ANALYSIS; FOUNDER EFFECT; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE (GENETICS); MEMBRANE PROTEINS; MIDDLE AGED; PEDIGREE; PHENOTYPE; POINT MUTATION; PRESENILIN-1; SEQUENCE ANALYSIS, DNA;

EID: 16944362050     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1004(1997)10:3<186::AID-HUMU2>3.0.CO;2-H     Document Type: Article

References (6)

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