-
1
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
2
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, and Brash DE (1994). Sunburn and p53 in the onset of skin cancer. Nature 372, 773-776.
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
Simon, J.A.4
Sharma, H.W.5
Kimmelman, J.6
Remington, L.7
Jacks, T.8
Brash, D.E.9
-
3
-
-
0025634118
-
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
-
Baker S, Preisinger A, Jessup J, Paraskeva C, Markowitz S, Wilson J, Hamilton S, and Vogelstein B (1990). p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 50, 7717-7722.
-
(1990)
Cancer Res
, vol.50
, pp. 7717-7722
-
-
Baker, S.1
Preisinger, A.2
Jessup, J.3
Paraskeva, C.4
Markowitz, S.5
Wilson, J.6
Hamilton, S.7
Vogelstein, B.8
-
4
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
Fisher DE (1994). Apoptosis in cancer therapy: crossing the threshold. Cell 78, 539-542.
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
5
-
-
0029845760
-
Structure and function of the p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
-
Harris CC (1996). Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies. J Natl Cancer Inst 88, 1442-1455.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1442-1455
-
-
Harris, C.C.1
-
6
-
-
0028204538
-
The 1993 Walter Hubert lecture: The role of the p53 tumour-suppressor gene in tumorigenesis
-
Levine A, Perry M, Chang A, Silver A, Dittmer D, Wu M, and Welsh D (1994). The 1993 Walter Hubert lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. Br J Cancer 69, 409-416.
-
(1994)
Br J Cancer
, vol.69
, pp. 409-416
-
-
Levine, A.1
Perry, M.2
Chang, A.3
Silver, A.4
Dittmer, D.5
Wu, M.6
Welsh, D.7
-
7
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, and Prives C (1996). p53: puzzle and paradigm. Genes Dev 10, 1054-1072.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
8
-
-
0030630531
-
Role of p53 in apoptosis
-
Canman C, and Kastan M (1997). Role of p53 in apoptosis. Adv Pnarmacol 41, 429-460.
-
(1997)
Adv Pnarmacol
, vol.41
, pp. 429-460
-
-
Canman, C.1
Kastan, M.2
-
9
-
-
0345059361
-
COOH-terminal domain of p53 modulates p53-mediated transcriptional transactivation, cell growth, and apoptosis
-
Zhou XL, Wang XW, Xu LX, Hagiwara K, Nagashima M, Wolkowicz R, Zurer I, Rotter V, and Harris CC (1999). COOH-terminal domain of p53 modulates p53-mediated transcriptional transactivation, cell growth, and apoptosis. Cancer Res 59, 843-848.
-
(1999)
Cancer Res
, vol.59
, pp. 843-848
-
-
Zhou, X.L.1
Wang, X.W.2
Xu, L.X.3
Hagiwara, K.4
Nagashima, M.5
Wolkowicz, R.6
Zurer, I.7
Rotter, V.8
Harris, C.C.9
-
10
-
-
0021616838
-
UV irradiation stimulates levels of p53 cellular antigen in nontransformed mouse cells
-
Maltzman W, and Czyzyk L (1984). UV irradiation stimulates levels of p53 cellular antigen in nontransformed mouse cells. Mol Cell Biol 4, 1689-1694.
-
(1984)
Mol Cell Biol
, vol.4
, pp. 1689-1694
-
-
Maltzman, W.1
Czyzyk, L.2
-
11
-
-
0027500246
-
Induction of nuclear accumulation of the tumor suppressor protein p53 by DNA-damaging agents
-
Fritsche M, Haessler C, and Brandner G (1993). Induction of nuclear accumulation of the tumor suppressor protein p53 by DNA-damaging agents. Oncogen 8, 307-318.
-
(1993)
Oncogen
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brandner, G.3
-
12
-
-
0026448672
-
Regulation of the specific DNA binding function of p53
-
Hupp T, Meek D, Midgley C, and Lane D (1992). Regulation of the specific DNA binding function of p53. Cell 71, 875-886.
-
(1992)
Cell
, vol.71
, pp. 875-886
-
-
Hupp, T.1
Meek, D.2
Midgley, C.3
Lane, D.4
-
13
-
-
0032988319
-
Regulation of p53 protein function through alterations in protein-folding pathways
-
Hupp TR (1999). Regulation of p53 protein function through alterations in protein-folding pathways. Cell Mol Life Sci 55, 88-95.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 88-95
-
-
Hupp, T.R.1
-
14
-
-
0032893878
-
Regulation of the p53 protein by the MDM2 oncoprotein - Thirty-eighth G.H.A. Clowes Memorial Award lecture
-
Freedman DA, and Levine AJ (1999). Regulation of the p53 protein by the MDM2 oncoprotein - thirty-eighth G.H.A. Clowes Memorial Award lecture. Cancer Res 59, 1-7.
-
(1999)
Cancer Res
, vol.59
, pp. 1-7
-
-
Freedman, D.A.1
Levine, A.J.2
-
15
-
-
0030731179
-
p53-mediated protective responses to UV irradiation
-
Smith ML, and Fornace AJ (1997). p53-mediated protective responses to UV irradiation. Proc Natl Acad Sci USA 94, 12255-12257.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12255-12257
-
-
Smith, M.L.1
Fornace, A.J.2
-
16
-
-
0006470452
-
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses
-
Amundson SA, Bittner M, Chen YD, Trent J, Meltzer P, and Fornace AJ (1999). Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses. Oncogen 18, 3666-3672.
-
(1999)
Oncogen
, vol.18
, pp. 3666-3672
-
-
Amundson, S.A.1
Bittner, M.2
Chen, Y.D.3
Trent, J.4
Meltzer, P.5
Fornace, A.J.6
-
17
-
-
0026702212
-
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
-
Zambetti G, Bargonetti J, Walker K, Prives C, and Levine A (1992). Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes Dev 6, 1143-1152.
-
(1992)
Genes Dev
, vol.6
, pp. 1143-1152
-
-
Zambetti, G.1
Bargonetti, J.2
Walker, K.3
Prives, C.4
Levine, A.5
-
18
-
-
0026770424
-
Wild-type p53 activates transcription in vitro
-
Farmer G, Bargonetti J, Zhu H, Friedman P, Prywes R, and Prives C (1992). Wild-type p53 activates transcription in vitro. Nature 358, 83-86.
-
(1992)
Nature
, vol.358
, pp. 83-86
-
-
Farmer, G.1
Bargonetti, J.2
Zhu, H.3
Friedman, P.4
Prywes, R.5
Prives, C.6
-
19
-
-
0025887476
-
Wild-type p53 can downmodulate the activity of various promoters
-
Ginsberg D, Mechta F, Yaniv M, and Oren M (1991). Wild-type p53 can downmodulate the activity of various promoters. Proc Natl Acad Sci USA 88, 9979-9983.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9979-9983
-
-
Ginsberg, D.1
Mechta, F.2
Yaniv, M.3
Oren, M.4
-
20
-
-
0027050648
-
Wild-type p53 binds to the TATA-binding protein and repress transcription
-
Seto E, Usheva A, Zambetti G, Momand J, Horikoshi N, Weinmann R, Levine A, and Shenk T (1992). Wild-type p53 binds to the TATA-binding protein and repress transcription. Proc Natl Acad Sci USA 89, 12028-12032.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 12028-12032
-
-
Seto, E.1
Usheva, A.2
Zambetti, G.3
Momand, J.4
Horikoshi, N.5
Weinmann, R.6
Levine, A.7
Shenk, T.8
-
21
-
-
0028842910
-
Reversal of in vitro p53 squelching by both TFIIB and TFIID
-
Liu X, and Berk AJ (1995). Reversal of in vitro p53 squelching by both TFIIB and TFIID. Mol Cell Biol 15, 6474-6478.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6474-6478
-
-
Liu, X.1
Berk, A.J.2
-
22
-
-
0033611568
-
p53 represses ribosomal gene transcription
-
Budde A, and Grummt I (1999). p53 represses ribosomal gene transcription. Oncogene 18, 1119-1124.
-
(1999)
Oncogene
, vol.18
, pp. 1119-1124
-
-
Budde, A.1
Grummt, I.2
-
23
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
Murphy M, Ahn J, Walker K, Hoffman W, Evans R, Levine A, and George D (1999). Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 13, 2490-2501.
-
(1999)
Genes Dev
, vol.13
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.3
Hoffman, W.4
Evans, R.5
Levine, A.6
George, D.7
-
24
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper J, Adami G, Wei N, Keyormarsi K, and Elledge S (1993). The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.1
Adami, G.2
Wei, N.3
Keyormarsi, K.4
Elledge, S.5
-
25
-
-
0028220204
-
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
-
Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, and Reed SI (1994). p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
26
-
-
0028919069
-
Involvement of the p53 tumor suppressor in repair of UV-type DNA damage
-
Smith ML, Chen IT, Zhan QM, Oconnor PM, and Fornace AJ (1995). Involvement of the p53 tumor suppressor in repair of UV-type DNA damage. Oncogene 10, 1053-1059.
-
(1995)
Oncogene
, vol.10
, pp. 1053-1059
-
-
Smith, M.L.1
Chen, I.T.2
Zhan, Q.M.3
Oconnor, P.M.4
Fornace, A.J.5
-
27
-
-
0029029741
-
Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance
-
Ford JM, and Hanawalt PC (1995). Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc Natl Acad Sci USA 92, 8876-8880.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8876-8880
-
-
Ford, J.M.1
Hanawalt, P.C.2
-
28
-
-
0030853074
-
Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts
-
Ford JM, and Hanawalt PC (1997). Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J Biol Chem 272, 28073-28080.
-
(1997)
J Biol Chem
, vol.272
, pp. 28073-28080
-
-
Ford, J.M.1
Hanawalt, P.C.2
-
29
-
-
0031416522
-
Wild-type p53 is required for heat shock and ultraviolet-light-enhanced repair of a UV-damaged reporter gene
-
McKay BC, Francis MA, and Rainbow AJ (1997). Wild-type p53 is required for heat shock and ultraviolet-light-enhanced repair of a UV-damaged reporter gene. Carcinogenesis 18, 245-249.
-
(1997)
Carcinogenesis
, vol.18
, pp. 245-249
-
-
McKay, B.C.1
Francis, M.A.2
Rainbow, A.J.3
-
30
-
-
0000516293
-
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
-
Hwang BJ, Ford JM, Hanawalt PC, and Chu G (1999). Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc Natl Acad Sci USA 96, 424-428.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 424-428
-
-
Hwang, B.J.1
Ford, J.M.2
Hanawalt, P.C.3
Chu, G.4
-
31
-
-
0032818868
-
Potential roles for p53 in nucleotide excision repair
-
McKay BC, Ljungman M, and Rainbow AJ (1999). Potential roles for p53 in nucleotide excision repair. Carcinogenesis 20, 1389-1396.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1389-1396
-
-
McKay, B.C.1
Ljungman, M.2
Rainbow, A.J.3
-
32
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
Serrano M, Lin AW, McCurrach ME, Beach D, and Lowe SW (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a). Cell 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
33
-
-
0033170538
-
Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light
-
McKay B, and Ljungman M (1999). Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light. Neoplasia 1, 276-284.
-
(1999)
Neoplasia
, vol.1
, pp. 276-284
-
-
McKay, B.1
Ljungman, M.2
-
34
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe S, Schmitt E, Smith S, Osborne B, and Jacks T (1993). p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.1
Schmitt, E.2
Smith, S.3
Osborne, B.4
Jacks, T.5
-
35
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke A, Purdie C, Harrison D, Morris R, Bird C, Hooper M, and Wyllie A (1993). Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362, 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.1
Purdie, C.2
Harrison, D.3
Morris, R.4
Bird, C.5
Hooper, M.6
Wyllie, A.7
-
36
-
-
0027332996
-
Differential induction of transcriptionally active p53 following UV or ionizing radiation - Defects in chromosome instability syndromes?
-
Lu X, and Lane DP (1993). Differential induction of transcriptionally active p53 following UV or ionizing radiation - defects in chromosome instability syndromes? Cell 75, 765-778.
-
(1993)
Cell
, vol.75
, pp. 765-778
-
-
Lu, X.1
Lane, D.P.2
-
37
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcón RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW, and Lowe SW (1999). Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284, 156-159.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcón, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
38
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, and Reed JC (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
39
-
-
0029003501
-
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
-
Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E, et al. (1995). Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15, 3032-3040.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
Angelo, L.S.4
Santee, S.M.5
Fujiwara, T.6
Roth, J.A.7
Deisseroth, A.B.8
Zhang, W.W.9
Kruzel, E.10
-
40
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G, and ElDeiry WS (1997). KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 17, 141-143.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.D.8
Zhou, J.Y.9
Muschel, R.10
Hamilton, S.R.11
Spinner, N.B.12
Markowitz, S.13
Wu, G.14
Eldeiry, W.S.15
-
41
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation-deficient p53
-
Haupt Y, Rowan S, Shaulian E, Vousden KH, and Oren M (1995). Induction of apoptosis in HeLa cells by transactivation-deficient p53. Gene Dev 9, 2170-2183.
-
(1995)
Gene Dev
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, K.H.4
Oren, M.5
-
42
-
-
0029958381
-
Reactive oxygen species are downstream mediators of p53-dependent apoptosis
-
Johnson TM, Yu ZX, Ferrans VJ, Lowenstein RA, and Finkel T (1996). Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc Natl Acad Sci USA 93, 11848-11852.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11848-11852
-
-
Johnson, T.M.1
Yu, Z.X.2
Ferrans, V.J.3
Lowenstein, R.A.4
Finkel, T.5
-
43
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, and Vogelstein B (1997). A model for p53-induced apoptosis. Nature 389, 300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
44
-
-
0033229866
-
p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
-
Li P-F, Dietz R, and von Harsdorf R (1999). p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J 18, 6027-6036.
-
(1999)
EMBO J
, vol.18
, pp. 6027-6036
-
-
Li, P.-F.1
Dietz, R.2
Von Harsdorf, R.3
-
45
-
-
0032500793
-
Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
-
Bennett M, Macdonald K, Chan SW, Luzio JP, Simari R, and Weissberg P (1998). Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science 282, 290-293.
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.W.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
46
-
-
0030868999
-
Ultraviolet-radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
-
Rehemtulla A, Hamilton CA, Chinnaiyan AM, and Dixit VM (1997). Ultraviolet-radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J Biol Chem 272, 25783-25786.
-
(1997)
J Biol Chem
, vol.272
, pp. 25783-25786
-
-
Rehemtulla, A.1
Hamilton, C.A.2
Chinnaiyan, A.M.3
Dixit, V.M.4
-
47
-
-
0033529581
-
Fas ligand: A sensor for DNA damage critical in skin cancer etiology
-
Hill LL, Ouhtit A, Loughlin SM, Kripke ML, Ananthaswamy HN, and Owen-Schaub LB (1999). Fas ligand: a sensor for DNA damage critical in skin cancer etiology. Science 285, 898-900.
-
(1999)
Science
, vol.285
, pp. 898-900
-
-
Hill, L.L.1
Ouhtit, A.2
Loughlin, S.M.3
Kripke, M.L.4
Ananthaswamy, H.N.5
Owen-Schaub, L.B.6
-
48
-
-
0033107657
-
The apoptosome: Heart and soul of the cell death machine
-
Chinnaiyan A (1999). The apoptosome: heart and soul of the cell death machine. Neoplasia 1, 5-15.
-
(1999)
Neoplasia
, vol.1
, pp. 5-15
-
-
Chinnaiyan, A.1
-
49
-
-
0344389027
-
Caspases: The proteases of the apoptotic pathway
-
Nuñez G, Benedict M, Hu Y, and Inohara N (1998). Caspases: the proteases of the apoptotic pathway. Oncogene 17, 3237-3245.
-
(1998)
Oncogene
, vol.17
, pp. 3237-3245
-
-
Nuñez, G.1
Benedict, M.2
Hu, Y.3
Inohara, N.4
-
50
-
-
0033230581
-
The cellular response to p53: The decision between life and death
-
Sionov R, and Haupt Y (1999). The cellular response to p53: the decision between life and death. Oncogene 18, 6145-6157.
-
(1999)
Oncogene
, vol.18
, pp. 6145-6157
-
-
Sionov, R.1
Haupt, Y.2
-
51
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner M, Werness B, Huibregtse J, Levine A, and Howley P (1990). The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1129-1136.
-
(1990)
Cell
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.2
Huibregtse, J.3
Levine, A.4
Howley, P.5
-
52
-
-
0028205667
-
Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway
-
Chowdary D, Dermody J, Jha K, and Ozer H (1994). Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway. Mol Cell Biol 14, 1997-2003.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1997-2003
-
-
Chowdary, D.1
Dermody, J.2
Jha, K.3
Ozer, H.4
-
53
-
-
0029952441
-
In vivo ubiquitination and proteasome-mediated degradation of p53
-
Maki CG, Huibregtse JM, and Howley PM (1996). In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res 56, 2649-2654.
-
(1996)
Cancer Res
, vol.56
, pp. 2649-2654
-
-
Maki, C.G.1
Huibregtse, J.M.2
Howley, P.M.3
-
54
-
-
0031015044
-
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation
-
Maki CG, and Howley PM (1997). Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol 17, 355-363.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 355-363
-
-
Maki, C.G.1
Howley, P.M.2
-
56
-
-
0030867774
-
The ubiquitin system
-
Varshavsky A (1997). The ubiquitin system. Trends Biochem Sci 22, 383-387.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 383-387
-
-
Varshavsky, A.1
-
57
-
-
0029867623
-
Proteasomes: Destruction as a programme
-
Hilt W, and Wolf DH (1996). Proteasomes: destruction as a programme. Trends Biochem Sci 21, 96-102.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 96-102
-
-
Hilt, W.1
Wolf, D.H.2
-
58
-
-
1342272916
-
How the cyclin became a cyclin: Regulated proteolysis in the cell cycle
-
Koepp D, Harper J, and Elledge S (1999). How the cyclin became a cyclin: regulated proteolysis in the cell cycle. Cell 97, 431-434.
-
(1999)
Cell
, vol.97
, pp. 431-434
-
-
Koepp, D.1
Harper, J.2
Elledge, S.3
-
59
-
-
0030016595
-
Structure and functions of the 20S and 26S proteosomes
-
Coux O, Tanaka K, and Goldberg A (1996). Structure and functions of the 20S and 26S proteosomes. Annu Rev Biochem 65, 801-847.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.3
-
60
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, and Oren M (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
62
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R, Tanaka H, and Yasuda H (1997). Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420, 25-27.
-
(1997)
FEBS Lett
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
63
-
-
0032512057
-
Mdm2 association with p53 targets its ubiquitination
-
Fuchs SY, Adler V, Buschmann T, Wu XW, and Ronai Z (1998). Mdm2 association with p53 targets its ubiquitination. Oncogene 17, 2543-2547.
-
(1998)
Oncogene
, vol.17
, pp. 2543-2547
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
Wu, X.W.4
Ronai, Z.5
-
64
-
-
0031702817
-
Regulation of Mdm2-directed degradation by the C-terminus of p53
-
Kubbutat M, Ludwig R, Ashcroft M, and Vousden K (1998). Regulation of Mdm2-directed degradation by the C-terminus of p53. Mol Cell Biol 18, 5690-5698.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5690-5698
-
-
Kubbutat, M.1
Ludwig, R.2
Ashcroft, M.3
Vousden, K.4
-
65
-
-
0030825813
-
p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding
-
Midgley CA, and Lane DP (1997). p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding. Oncogene 15, 1179-1189.
-
(1997)
Oncogene
, vol.15
, pp. 1179-1189
-
-
Midgley, C.A.1
Lane, D.P.2
-
66
-
-
0032169459
-
JNK targets p53 ubiquitination and degradation in nonstressed cells
-
Fuchs SY, Adler V, Buschmann T, Yin ZM, Wu XW, Jones SN, and Ronai Z (1998). JNK targets p53 ubiquitination and degradation in nonstressed cells. Genes Dev 12, 2658-2663.
-
(1998)
Genes Dev
, vol.12
, pp. 2658-2663
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
Yin, Z.M.4
Wu, X.W.5
Jones, S.N.6
Ronai, Z.7
-
67
-
-
0032541565
-
Stress-activated kinases regulate protein stability
-
Fuchs SY, Fried VA, and Ronai Z (1998). Stress-activated kinases regulate protein stability. Oncogene 17, 1483-1490.
-
(1998)
Oncogene
, vol.17
, pp. 1483-1490
-
-
Fuchs, S.Y.1
Fried, V.A.2
Ronai, Z.3
-
68
-
-
0031014946
-
Proteolytic cleavage of human p53 by calpain: A potential regulator of protein stability
-
Kubbutat MHG, and Vousden KH (1997). Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability. Mol Cell Biol 17, 460-468.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 460-468
-
-
Kubbutat, M.H.G.1
Vousden, K.H.2
-
69
-
-
0030987086
-
Proteolysis by calpains: A possible contribution to degradation of p53
-
Pariat M, Carillo S, Molinari M, Salvat C, Debussche L, Bracco L, Milner J, and Piechaczyk M (1997). Proteolysis by calpains: a possible contribution to degradation of p53. Mol Cell Biol 17, 2806-2815.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2806-2815
-
-
Pariat, M.1
Carillo, S.2
Molinari, M.3
Salvat, C.4
Debussche, L.5
Bracco, L.6
Milner, J.7
Piechaczyk, M.8
-
70
-
-
0030992491
-
On the involvement of calpains in the degradation of the tumor suppressor protein p53
-
Gonen H, Shkedy D, Barnoy S, Kosower NS, and Ciechanover A (1997). On the involvement of calpains in the degradation of the tumor suppressor protein p53. FEBS Lett 406, 17-22.
-
(1997)
FEBS Lett
, vol.406
, pp. 17-22
-
-
Gonen, H.1
Shkedy, D.2
Barnoy, S.3
Kosower, N.S.4
Ciechanover, A.5
-
71
-
-
0033590624
-
Inhibition of RNA polymerase II as a trigger for the p53 response
-
Ljungman M, Zhang FF, Chen F, Rainbow AJ, and McKay BC (1999). Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 18, 583-592.
-
(1999)
Oncogene
, vol.18
, pp. 583-592
-
-
Ljungman, M.1
Zhang, F.F.2
Chen, F.3
Rainbow, A.J.4
McKay, B.C.5
-
72
-
-
0028030791
-
UV-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle
-
Yamaizumi M, and Sugano T (1994). UV-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle. Oncogene 9, 2775-2784.
-
(1994)
Oncogene
, vol.9
, pp. 2775-2784
-
-
Yamaizumi, M.1
Sugano, T.2
-
73
-
-
0029785723
-
Blockage of RNA polymerase as a possible trigger for UV light-induced apoptosis
-
Ljungman M, and Zhang F (1996). Blockage of RNA polymerase as a possible trigger for UV light-induced apoptosis. Oncogene 13, 823-831.
-
(1996)
Oncogene
, vol.13
, pp. 823-831
-
-
Ljungman, M.1
Zhang, F.2
-
74
-
-
0031426286
-
Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes
-
Dumaz N, Duthu A, Ehrhart JC, Drougard C, Appella E, Anderson CW, May P, Sarasin A, and DayaGrosjean L (1997); Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes. Mol Carcinogen 20, 340-347.
-
(1997)
Mol Carcinogen
, vol.20
, pp. 340-347
-
-
Dumaz, N.1
Duthu, A.2
Ehrhart, J.C.3
Drougard, C.4
Appella, E.5
Anderson, C.W.6
May, P.7
Sarasin, A.8
DayaGrosjean, L.9
-
75
-
-
0032490853
-
Persistent DNA damage induced by ultraviolet light inhibits p21 (waf1) and bax expression: Implications for DNA repair, UV sensitivity and the induction of apoptosis
-
McKay BC, Ljungman M, and Rainbow AJ (1998). Persistent DNA damage induced by ultraviolet light inhibits p21 (waf1) and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis. Oncogene 17, 545-555.
-
(1998)
Oncogene
, vol.17
, pp. 545-555
-
-
McKay, B.C.1
Ljungman, M.2
Rainbow, A.J.3
-
76
-
-
0018163396
-
Gene and transcription mapping by radiation effects
-
Sauerbier W, and Hercules K (1978). Gene and transcription mapping by radiation effects. Annu Rev Genet 12, 329-363.
-
(1978)
Annu Rev Genet
, vol.12
, pp. 329-363
-
-
Sauerbier, W.1
Hercules, K.2
-
77
-
-
0025610725
-
Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro
-
Selby C, and Sancar A (1990). Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro. J Biol Chem 265, 21330-21336.
-
(1990)
J Biol Chem
, vol.265
, pp. 21330-21336
-
-
Selby, C.1
Sancar, A.2
-
78
-
-
0028106162
-
Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template
-
Donahue BA, Yin S, Taylor JS, Reines D, and Hanawalt PC (1994). Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template. Proc Natl Acad Sci USA 91, 8502-8506.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8502-8506
-
-
Donahue, B.A.1
Yin, S.2
Taylor, J.S.3
Reines, D.4
Hanawalt, P.C.5
-
79
-
-
0028600051
-
The MO15 cell cycle kinase is associated with the TFIIH transcription DNA repair factor
-
Roy R, Adamczewski JP, Seroz T, Vermeulen W, Tassan JP, Schaeffer L, Nigg EA, Hoeijmakers JHJ, and Egly JM (1994). The MO15 cell cycle kinase is associated with the TFIIH transcription DNA repair factor. Cell 79, 1093-1101.
-
(1994)
Cell
, vol.79
, pp. 1093-1101
-
-
Roy, R.1
Adamczewski, J.P.2
Seroz, T.3
Vermeulen, W.4
Tassan, J.P.5
Schaeffer, L.6
Nigg, E.A.7
Hoeijmakers, J.H.J.8
Egly, J.M.9
-
80
-
-
0030724673
-
p53 is phosphorylated by CDK7-cyclin H in a p36(MAT1)-dependent manner
-
Ko LJ, Shieh SY, Chen XB, Jayaraman L, Tamai K, Taya Y, Prives C, and Pan ZQ (1997). p53 is phosphorylated by CDK7-cyclin H in a p36(MAT1)-dependent manner. Mol Cell Biol 17, 7220-7229.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 7220-7229
-
-
Ko, L.J.1
Shieh, S.Y.2
Chen, X.B.3
Jayaraman, L.4
Tamai, K.5
Taya, Y.6
Prives, C.7
Pan, Z.Q.8
-
81
-
-
0030610565
-
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro
-
Lu H, Fisher RP, Bailey P, and Levine AJ (1997). The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Mol Cell Biol 17, 923-5934.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 923-5934
-
-
Lu, H.1
Fisher, R.P.2
Bailey, P.3
Levine, A.J.4
-
82
-
-
0029669982
-
TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74
-
Dikstein R, Ruppert S, and Tjian R (1996). TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74. Cell 84, 81-790.
-
(1996)
Cell
, vol.84
, pp. 81-790
-
-
Dikstein, R.1
Ruppert, S.2
Tjian, R.3
-
83
-
-
0030447943
-
The TAF(II)250 subunit of TFIID has histone acetyltransferase activity
-
Mizzen CA, Yang XJ, Kokubo T, Brownell JE, Bannister AJ, OwenHughes T, Workman J, Wang L, Berger SL, Kouzarides T, Nakatani Y, and Allis CD (1996). The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 87, 261-1270.
-
(1996)
Cell
, vol.87
, pp. 261-1270
-
-
Mizzen, C.A.1
Yang, X.J.2
Kokubo, T.3
Brownell, J.E.4
Bannister, A.J.5
OwenHughes, T.6
Workman, J.7
Wang, L.8
Berger, S.L.9
Kouzarides, T.10
Nakatani, Y.11
Allis, C.D.12
-
84
-
-
1842378642
-
The MDM2 C-terminal region binds to TAF (II) 250 and is required for MDM2 regulation of the cyclin a promoter
-
Léveillard T, and Wasylyk B (1997). The MDM2 C-terminal region binds to TAF (II) 250 and is required for MDM2 regulation of the cyclin A promoter. J Biol Chem 272, 30651-30661.
-
(1997)
J Biol Chem
, vol.272
, pp. 30651-30661
-
-
Léveillard, T.1
Wasylyk, B.2
-
85
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu W, and Roeder RG (1997). Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90, 595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
86
-
-
0032530486
-
DNA damage activates p53 through a phosphorylation-acetylation cascade
-
Sakaguchi K, Herrera JE, Saito S, Miki T, Bustin M, Vassilev A, Anderson CW, and Appella E (1998). DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev 12, 2831-2841.
-
(1998)
Genes Dev
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustin, M.5
Vassilev, A.6
Anderson, C.W.7
Appella, E.8
-
87
-
-
0025007474
-
Drug and metabolite-induced perturbations in nuclear structure and function: A review
-
Brasch K (1990). Drug and metabolite-induced perturbations in nuclear structure and function: a review. Biochem Cell Biol 68, 408-426.
-
(1990)
Biochem Cell Biol
, vol.68
, pp. 408-426
-
-
Brasch, K.1
-
88
-
-
0030005052
-
Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains
-
Haaf T, and Ward DC (1996). Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains. Exp Cell Res 224, 163-173.
-
(1996)
Exp Cell Res
, vol.224
, pp. 163-173
-
-
Haaf, T.1
Ward, D.C.2
-
89
-
-
0032939925
-
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
-
Blattner C, Sparks A, and Lane D (1999). Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol 19, 3704-3713.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3704-3713
-
-
Blattner, C.1
Sparks, A.2
Lane, D.3
-
90
-
-
0022310512
-
Chemical changes induced in DNA by ionizing radiation
-
Hutchinson F (1985). Chemical changes induced in DNA by ionizing radiation. Prog Nucleic Acids Res Mol Biol 32, 115-154.
-
(1985)
Prog Nucleic Acids Res Mol Biol
, vol.32
, pp. 115-154
-
-
Hutchinson, F.1
-
91
-
-
0024195429
-
DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and repair-ability
-
Ward JF (1988). DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and repair-ability. Prog Nucleic Acids Res Mol Biol 35, 95-125.
-
(1988)
Prog Nucleic Acids Res Mol Biol
, vol.35
, pp. 95-125
-
-
Ward, J.F.1
-
92
-
-
0032828689
-
Repair of radiation-induced DNA strand breaks does not occur preferentially in transcriptionally active DNA
-
Ljungman M (1999). Repair of radiation-induced DNA strand breaks does not occur preferentially in transcriptionally active DNA. Radiat Res 152, 444-449.
-
(1999)
Radiat Res
, vol.152
, pp. 444-449
-
-
Ljungman, M.1
-
93
-
-
0021905437
-
DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
-
Bohr VA, Smith CL, Okumoto DS, and Hanawalt PC (1985). DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40, 359-369.
-
(1985)
Cell
, vol.40
, pp. 359-369
-
-
Bohr, V.A.1
Smith, C.L.2
Okumoto, D.S.3
Hanawalt, P.C.4
-
94
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan M, Onyekwere O, Sidransky D, Vogelstein B, and Craig R (1991). Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51, 6304-6311.
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.5
-
95
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
-
Nelson WG, and Kastan MB (1994). DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol Cell Biol 14, 1815-1823.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
96
-
-
0026773938
-
Localized torsional tension in the DNA of human cells
-
Ljungman M, and Hanawalt PC (1992). Localized torsional tension in the DNA of human cells. Proc Natl Acad Sci USA 89, 6055-6059.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6055-6059
-
-
Ljungman, M.1
Hanawalt, P.C.2
-
97
-
-
0029052136
-
Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo
-
Ljungman M, and Hanawalt P (1995). Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo. Nucleic Acids Res 23, 1782-1789.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1782-1789
-
-
Ljungman, M.1
Hanawalt, P.2
-
98
-
-
0032850745
-
Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment
-
Smilenov LB, Dhar S, and Pandita TK (1999). Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment. Mol Cell Biol 19, 6963-6971.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6963-6971
-
-
Smilenov, L.B.1
Dhar, S.2
Pandita, T.K.3
-
99
-
-
0029897210
-
Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G (1) arrest
-
Huang LC, Clarkin KC, and Wahl GM (1996). Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G (1) arrest. Proc Natl Acad Sci USA 93, 4827-4832.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4827-4832
-
-
Huang, L.C.1
Clarkin, K.C.2
Wahl, G.M.3
-
100
-
-
0033600234
-
The tyrosine kinase c-AbI regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin WG, Levrero M, and Wang JYJ (1999). The tyrosine kinase c-AbI regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 399, 806-809.
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
Melino, G.4
Kaelin, W.G.5
Levrero, M.6
Wang, J.Y.J.7
-
101
-
-
0033600240
-
Interaction of c-AbI and p73 alpha and their collaboration to induce apoptosis
-
Agami R, Blandino G, Oren M, and Shaul Y (1999). Interaction of c-AbI and p73 alpha and their collaboration to induce apoptosis. Nature 399, 809-813.
-
(1999)
Nature
, vol.399
, pp. 809-813
-
-
Agami, R.1
Blandino, G.2
Oren, M.3
Shaul, Y.4
-
102
-
-
0033600235
-
P73 is regulated by tyrosine kinase c-AbI in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, Sun XG, Gu JJ, Huang YY, Lu H, Kharbanda S, Weichselbaum R, and Kufe D (1999). P73 is regulated by tyrosine kinase c-AbI in the apoptotic response to DNA damage. Nature 399, 814-817.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.G.4
Gu, J.J.5
Huang, Y.Y.6
Lu, H.7
Kharbanda, S.8
Weichselbaum, R.9
Kufe, D.10
-
103
-
-
0033605576
-
c-AbI neutralizes the inhibitory effect of Mdm2 on p53
-
Sionov RV, Moallem E, Berger M, Kazaz A, Gerlitz O, Ben-Neriah Y, Oren M, and Haupt Y (1999). c-AbI neutralizes the inhibitory effect of Mdm2 on p53. J Biol Chem 274, 8371-8374.
-
(1999)
J Biol Chem
, vol.274
, pp. 8371-8374
-
-
Sionov, R.V.1
Moallem, E.2
Berger, M.3
Kazaz, A.4
Gerlitz, O.5
Ben-Neriah, Y.6
Oren, M.7
Haupt, Y.8
-
104
-
-
0029134790
-
Defective induction of stress-activated protein kinase activity in ataxia telangiectasia cells exposed to ionizing radiation
-
Shafman TD, Saleem A, Kyriakis J, Weichselbaum R, Kharbanda S, and Kufe DW (1995). Defective induction of stress-activated protein kinase activity in ataxia telangiectasia cells exposed to ionizing radiation. Cancer Res 55, 3242-3245.
-
(1995)
Cancer Res
, vol.55
, pp. 3242-3245
-
-
Shafman, T.D.1
Saleem, A.2
Kyriakis, J.3
Weichselbaum, R.4
Kharbanda, S.5
Kufe, D.W.6
-
105
-
-
0031840253
-
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
-
Waterman M, Stavridi E, Waterman J, and Halazonetis T (1998). ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. War Genet 19, 175-178.
-
(1998)
War Genet
, vol.19
, pp. 175-178
-
-
Waterman, M.1
Stavridi, E.2
Waterman, J.3
Halazonetis, T.4
-
106
-
-
0027980319
-
Inhibitors of the proteosome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock K, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, and Goldberg A (1994). Inhibitors of the proteosome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78, 761-771.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.8
-
107
-
-
0033538443
-
Activation of the cell death program by nitric oxide involves inhibition of the proteasome
-
Glockzin S, von Knethen A, Scheffner M, and Brune B (1999). Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J Biol Chem 274, 19581-19586.
-
(1999)
J Biol Chem
, vol.274
, pp. 19581-19586
-
-
Glockzin, S.1
Von Knethen, A.2
Scheffner, M.3
Brune, B.4
-
108
-
-
0033151867
-
Excess beta-catenin promotes accumulation of transcriptionally active p53
-
Damalas A, Ben-Ze'ev A, Simcha I, Shtutman N, Leal JFN, Zhurinsky J, Geiger B, and Oren M (1999). Excess beta-catenin promotes accumulation of transcriptionally active p53. EMBO J 18, 3054-3063.
-
(1999)
EMBO J
, vol.18
, pp. 3054-3063
-
-
Damalas, A.1
Ben-Ze'ev, A.2
Simcha, I.3
Shtutman, N.4
Leal, J.F.N.5
Zhurinsky, J.6
Geiger, B.7
Oren, M.8
-
109
-
-
0027295481
-
Spectrum of DNA-platinum adduct recognition by prokaryotic and eukaryotic DNA-dependent RNA polymerases
-
Corda Y, Anin MF, Leng M, and Job D (1993). Spectrum of DNA-platinum adduct recognition by prokaryotic and eukaryotic DNA-dependent RNA polymerases. Biochemistry 32, 8582-85884.
-
(1993)
Biochemistry
, vol.32
, pp. 8582-85884
-
-
Corda, Y.1
Anin, M.F.2
Leng, M.3
Job, D.4
-
110
-
-
0028812839
-
DNA adducts of cis-diamminedichloroplatinum(II) and its trans-isomer inhibit RNA polymerase II differentially in vivo
-
Mello JA, Lippard SJ, and Essigmann JM (1995). DNA adducts of cis-diamminedichloroplatinum(II) and its trans-isomer inhibit RNA polymerase II differentially in vivo. Biochemistry 34, 14783-14791.
-
(1995)
Biochemistry
, vol.34
, pp. 14783-14791
-
-
Mello, J.A.1
Lippard, S.J.2
Essigmann, J.M.3
-
111
-
-
0032851842
-
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
-
Hickman MJ, and Samson LD (1999). Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc Natl Acad Sci USA 96, 10764-10769.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10764-10769
-
-
Hickman, M.J.1
Samson, L.D.2
-
112
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia telangiectasia
-
Kastan MB, Zhan QM, Eldeiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, and Fornace AJ (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia telangiectasia. Cell 71, 587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.M.2
Eldeiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, A.J.9
-
113
-
-
0030786912
-
Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation
-
Jongmans W, Vuillaume M, Chrzanowska K, Smeets D, Sperling K, and Hall J (1997). Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation. Mol Cell Biol 17, 5016-5022.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5016-5022
-
-
Jongmans, W.1
Vuillaume, M.2
Chrzanowska, K.3
Smeets, D.4
Sperling, K.5
Hall, J.6
-
114
-
-
0032076248
-
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to cellular DNA damage response
-
Camey J, Maser R, Olivares H, Davis E, Le Beau M, Yates J III, Hays L, Morgan W, and Petrini J (1998). The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to cellular DNA damage response. Cell 93, 477-486.
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Camey, J.1
Maser, R.2
Olivares, H.3
Davis, E.4
Le Beau, M.5
Yates III, J.6
Hays, L.7
Morgan, W.8
Petrini, J.9
-
115
-
-
0027486024
-
Ionizing radiation and UV induction of p53 by different pathways in ataxia telangiectasia cells
-
Khanna KK, and Lavin MF (1993). Ionizing radiation and UV induction of p53 by different pathways in ataxia telangiectasia cells. Oncogene 8, 3307-3312.
-
(1993)
Oncogene
, vol.8
, pp. 3307-3312
-
-
Khanna, K.K.1
Lavin, M.F.2
-
116
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of Brca-1 in the DNA damage response to double-strand breaks
-
Cortez D, Wang Y, Qin J, and Elledge S (1999). Requirement of ATM-dependent phosphorylation of Brca-1 in the DNA damage response to double-strand breaks. Science 286, 1162-1166.
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.4
-
117
-
-
0033613099
-
Purification and DNA binding properties of the ataxia telangiectasia gene product ATM
-
Smith GCM, Cary RB, Lakin ND, Hann BC, Teo SH, Chen DJ, and Jackson SP (1999). Purification and DNA binding properties of the ataxia telangiectasia gene product ATM. Proc Natl Acad Sci USA 96, 11134-11139.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11134-11139
-
-
Smith, G.C.M.1
Cary, R.B.2
Lakin, N.D.3
Hann, B.C.4
Teo, S.H.5
Chen, D.J.6
Jackson, S.P.7
-
118
-
-
0033520432
-
Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation
-
Suzuki K, Kodama S, and Watanabe M (1999). Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J Biol Chem 274, 25571-25575.
-
(1999)
J Biol Chem
, vol.274
, pp. 25571-25575
-
-
Suzuki, K.1
Kodama, S.2
Watanabe, M.3
-
119
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, and Siliciano JD (1998). Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
120
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATN in response to DNA damage
-
Banin S, Moyal L, Shieh SY, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, and Ziv Y (1998). Enhanced phosphorylation of p53 by ATN in response to DNA damage. Science 281, 1674-1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.Y.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
121
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, Karnitz LM, and Abraham RT (1999). Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 59, 4375-4382.
-
(1999)
Cancer Res
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
122
-
-
0033533725
-
Caffeine inhibits the checkpoint kinase ATM
-
Blasina A, Price BD, Turenne GA, and McGowan CH (1999). Caffeine inhibits the checkpoint kinase ATM. Curr Biol 9, 1135-1138.
-
(1999)
Curr Biol
, vol.9
, pp. 1135-1138
-
-
Blasina, A.1
Price, B.D.2
Turenne, G.A.3
McGowan, C.H.4
-
123
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert PF, Kashanchi F, Radonovich MF, Shiekhattar R, and Brady JN (1998). Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem 273, 33048-33053.
-
(1998)
J Biol Chem
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
124
-
-
0033609306
-
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity
-
Unger T, Sionov RV, Moallem E, Yee CL, Howley PM, Oren M, and Haupt Y (1999). Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene 18, 3205-3212.
-
(1999)
Oncogene
, vol.18
, pp. 3205-3212
-
-
Unger, T.1
Sionov, R.V.2
Moallem, E.3
Yee, C.L.4
Howley, P.M.5
Oren, M.6
Haupt, Y.7
-
125
-
-
0031903407
-
Phosphorylation of p53: A novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells
-
Pise-Masison C, Radonovich M, Sakaguchi K, Appella E, and Brady J (1998). Phosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells. J Virol 72, 6348-6355.
-
(1998)
J Virol
, vol.72
, pp. 6348-6355
-
-
Pise-Masison, C.1
Radonovich, M.2
Sakaguchi, K.3
Appella, E.4
Brady, J.5
-
126
-
-
0032189483
-
Inhibition of phosphoinostide 3-kinase related kinases by the radiosenzitizing agent, wortmannin
-
Sarkaria J, Tibbetts R, Busby E, Kennedy A, Hill D, and Abraham R (1998). Inhibition of phosphoinostide 3-kinase related kinases by the radiosenzitizing agent, wortmannin. Cancer Res 58, 4375-4382.
-
(1998)
Cancer Res
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.1
Tibbetts, R.2
Busby, E.3
Kennedy, A.4
Hill, D.5
Abraham, R.6
-
127
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C, and Abraham RT (1999). A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev 13, 152-157.
-
(1999)
Genes Dev
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
128
-
-
0032560556
-
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
-
Wright J, Keegan K, Herendeen D, Bentley N, Carr A, Hoekstra M, and Concannon P (1998). Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc Natl Acad Sci USA 95, 7445-7450.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7445-7450
-
-
Wright, J.1
Keegan, K.2
Herendeen, D.3
Bentley, N.4
Carr, A.5
Hoekstra, M.6
Concannon, P.7
-
129
-
-
0032472330
-
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
-
Cliby WA, Roberts CJ, Cimprich KA, Stringer CM, Lamb JR, Schreiber SL, and Friend SH (1998). Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J 17, 159-169.
-
(1998)
EMBO J
, vol.17
, pp. 159-169
-
-
Cliby, W.A.1
Roberts, C.J.2
Cimprich, K.A.3
Stringer, C.M.4
Lamb, J.R.5
Schreiber, S.L.6
Friend, S.H.7
-
130
-
-
0033536164
-
The ataxia telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53
-
Lakin N, Hann B, and Jackson S (1999). The ataxia telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53. Oncogene 18, 3989-3995.
-
(1999)
Oncogene
, vol.18
, pp. 3989-3995
-
-
Lakin, N.1
Hann, B.2
Jackson, S.3
-
131
-
-
0033027346
-
Covalent and noncovalent modifiers of the p53 protein
-
Jayaraman L, and Prives C (1999). Covalent and noncovalent modifiers of the p53 protein. Cell Mol Life Sci 55, 76-87.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 76-87
-
-
Jayaraman, L.1
Prives, C.2
-
132
-
-
0033532174
-
The ability of p53 to activate downstream genes p21WAF1/cip1 and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein
-
Kachnic LA, Wu B, Wunsch H, Mekeel KL, DeFrank JS, Tang W, and Powell SN (1999). The ability of p53 to activate downstream genes p21WAF1/cip1 and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein. J Biol Chem 274, 13111-13117.
-
(1999)
J Biol Chem
, vol.274
, pp. 13111-13117
-
-
Kachnic, L.A.1
Wu, B.2
Wunsch, H.3
Mekeel, K.L.4
DeFrank, J.S.5
Tang, W.6
Powell, S.N.7
-
133
-
-
0033602179
-
Phosphorylation of p53 protein in response to ionizing radiation occurs at multiple sites in both normal and DNA-PK deficient cells
-
Abraham J, Spaner D, and Benchimol S (1999). Phosphorylation of p53 protein in response to ionizing radiation occurs at multiple sites in both normal and DNA-PK deficient cells. Oncogene 18, 1521-1527.
-
(1999)
Oncogene
, vol.18
, pp. 1521-1527
-
-
Abraham, J.1
Spaner, D.2
Benchimol, S.3
-
134
-
-
17444370101
-
Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells
-
Araki R, Fukumura R, Fujimori A, Taya Y, Shiloh Y, Kurimasa A, Burma S, Li GC, Chen DJ, Sato K, Hoki Y, Tatsumi K, and Abe M (1999). Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells. Cancer Res 59, 3543-3546.
-
(1999)
Cancer Res
, vol.59
, pp. 3543-3546
-
-
Araki, R.1
Fukumura, R.2
Fujimori, A.3
Taya, Y.4
Shiloh, Y.5
Kurimasa, A.6
Burma, S.7
Li, G.C.8
Chen, D.J.9
Sato, K.10
Hoki, Y.11
Tatsumi, K.12
Abe, M.13
-
135
-
-
0033167979
-
DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage
-
Jimenez GS, Bryntesson F, Torres-Arzayus MI, Priestley A, Beeche M, Saito S, Sakaguchi K, Appella E, Jeggo PA, Taccioli GE, Wahl GM, and Hubank M (1999). DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage. Nature 400, 81-83.
-
(1999)
Nature
, vol.400
, pp. 81-83
-
-
Jimenez, G.S.1
Bryntesson, F.2
Torres-Arzayus, M.I.3
Priestley, A.4
Beeche, M.5
Saito, S.6
Sakaguchi, K.7
Appella, E.8
Jeggo, P.A.9
Taccioli, G.E.10
Wahl, G.M.11
Hubank, M.12
-
136
-
-
0029941651
-
P53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts
-
Huang LC, Clarkin KC, and Wahl GM (1996). P53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts. Cancer Res 56, 2940-2944.
-
(1996)
Cancer Res
, vol.56
, pp. 2940-2944
-
-
Huang, L.C.1
Clarkin, K.C.2
Wahl, G.M.3
-
137
-
-
0029979313
-
DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin
-
Take Y, Kumano M, Teraoka H, Nishimura S, and Okuyama A (1996). DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin. Biochem Biophys Res Commun 221, 207-212.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 207-212
-
-
Take, Y.1
Kumano, M.2
Teraoka, H.3
Nishimura, S.4
Okuyama, A.5
-
138
-
-
0030693181
-
JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases
-
Hu MCT, Qiu WR, and Wang YP (1997). JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases. Oncogene 15, 2277-2287.
-
(1997)
Oncogene
, vol.15
, pp. 2277-2287
-
-
Hu, M.C.T.1
Qiu, W.R.2
Wang, Y.P.3
-
139
-
-
0028966941
-
p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
-
Milne DM, Campbell LE, Campbell DG, and Meek DW (1995). p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J Biol Chem 270, 5511-5518.
-
(1995)
J Biol Chem
, vol.270
, pp. 5511-5518
-
-
Milne, D.M.1
Campbell, L.E.2
Campbell, D.G.3
Meek, D.W.4
-
140
-
-
0032167915
-
MEKK1/JNK signaling stabilizes and activates p53
-
Fuchs SY, Adler V, Pincus MR, and Ronai Z (1998). MEKK1/JNK signaling stabilizes and activates p53. Proc Natl Acad Sci USA 95, 10541-10546.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10541-10546
-
-
Fuchs, S.Y.1
Adler, V.2
Pincus, M.R.3
Ronai, Z.4
-
141
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi M, Lin A, Smeal T, Minden A, and Karin M (1993). Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 7, 2135-2148.
-
(1993)
Genes Dev
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
142
-
-
0030925565
-
Ataxia telangiectasia mutant protein activates c-AbI tyrosine kinase in response to ionizing radiation
-
Baskaran R, Wood LD, Whitaker LL, Canman CE, Morgan SE, Xu Y, Barlow C, Baltimore D, Wynshaw-Boris A, Kastan MB, and Wang JYJ (1997). Ataxia telangiectasia mutant protein activates c-AbI tyrosine kinase in response to ionizing radiation. Nature 387, 516-519.
-
(1997)
Nature
, vol.387
, pp. 516-519
-
-
Baskaran, R.1
Wood, L.D.2
Whitaker, L.L.3
Canman, C.E.4
Morgan, S.E.5
Xu, Y.6
Barlow, C.7
Baltimore, D.8
Wynshaw-Boris, A.9
Kastan, M.B.10
Wang, J.Y.J.11
-
143
-
-
0030992749
-
Interaction between ATM protein and c-AbI in response to DNA damage
-
Shafman T, Kanna KK, Kedar P, Spring K, Kozlov S, Yen T, Hobson K, Gatei M, Zhang N, Watters D, Egerton M, Shiloh Y, Kharbanda S, Kufe D, and Lavine MF (1997). Interaction between ATM protein and c-AbI in response to DNA damage. Nature 387, 520-523.
-
(1997)
Nature
, vol.387
, pp. 520-523
-
-
Shafman, T.1
Kanna, K.K.2
Kedar, P.3
Spring, K.4
Kozlov, S.5
Yen, T.6
Hobson, K.7
Gatei, M.8
Zhang, N.9
Watters, D.10
Egerton, M.11
Shiloh, Y.12
Kharbanda, S.13
Kufe, D.14
Lavine, M.F.15
-
144
-
-
0030945148
-
Functional interaction between DNA-PK and c-AbI in response to DNA damage
-
Kharbanda S, Pandey P, Jin SF, Inoue S, Bharti A, Yuan ZM, Weichselbaum R, Weaver D, and Kufe D (1997). Functional interaction between DNA-PK and c-AbI in response to DNA damage. Nature 386, 732-735.
-
(1997)
Nature
, vol.386
, pp. 732-735
-
-
Kharbanda, S.1
Pandey, P.2
Jin, S.F.3
Inoue, S.4
Bharti, A.5
Yuan, Z.M.6
Weichselbaum, R.7
Weaver, D.8
Kufe, D.9
-
145
-
-
0030670332
-
p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs
-
Knippschild U, Milne DM, Campbell LE, DeMaggio AJ, Christenson E, Hoekstra MF, and Meek DW (1997). p53 is phosphorylated In vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs. Oncogene 15, 1727-1736.
-
(1997)
Oncogene
, vol.15
, pp. 1727-1736
-
-
Knippschild, U.1
Milne, D.M.2
Campbell, L.E.3
DeMaggio, A.J.4
Christenson, E.5
Hoekstra, M.F.6
Meek, D.W.7
-
146
-
-
0025143302
-
The p53 tumor suppressor protein is phosphorylated at serine 389 by casein kinase II
-
Meek D, Simon S, Kikkawa U, and Eckhart W (1990).The p53 tumor suppressor protein is phosphorylated at serine 389 by casein kinase II. EMBO J 9, 3253-3260.
-
(1990)
EMBO J
, vol.9
, pp. 3253-3260
-
-
Meek, D.1
Simon, S.2
Kikkawa, U.3
Eckhart, W.4
-
147
-
-
0029944721
-
Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation
-
Hall SR, Campbell LE, and Meek DW (1996). Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation. Nucleic Acids Res 24, 1119-1126.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1119-1126
-
-
Hall, S.R.1
Campbell, L.E.2
Meek, D.W.3
-
148
-
-
0029027040
-
Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner
-
Hupp TR, and Lane DP (1995). Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner. J Biol Chem 270, 18165-18174.
-
(1995)
J Biol Chem
, vol.270
, pp. 18165-18174
-
-
Hupp, T.R.1
Lane, D.P.2
-
149
-
-
0029951978
-
Casein kinase 2 inhibits the renaturation of complementary DNA strands mediated by p53 protein
-
Filhol O, Baudier J, Chambaz EM, and Cochet C (1996). Casein kinase 2 inhibits the renaturation of complementary DNA strands mediated by p53 protein. Biochem J 316, 331-335.
-
(1996)
Biochem J
, vol.316
, pp. 331-335
-
-
Filhol, O.1
Baudier, J.2
Chambaz, E.M.3
Cochet, C.4
-
150
-
-
0028861059
-
Mapping of the interaction sites of the growth suppressor protein p53 with the regulatory b-subunit of protein kinase CK2
-
Appel K, Wagner P, Boldyreff B, Issinger O-G, and Montenarh M (1995). Mapping of the interaction sites of the growth suppressor protein p53 with the regulatory b-subunit of protein kinase CK2. Oncogene 11, 1971-1978.
-
(1995)
Oncogene
, vol.11
, pp. 1971-1978
-
-
Appel, K.1
Wagner, P.2
Boldyreff, B.3
Issinger, O.-G.4
Montenarh, M.5
-
151
-
-
0030790778
-
Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53
-
Sakaguchi K, Sakamoto H, Lewis MS, Anderson CW, Erickson JW, Appella E, and Xie D (1997). Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. Biochemistry 36, 10117-10124.
-
(1997)
Biochemistry
, vol.36
, pp. 10117-10124
-
-
Sakaguchi, K.1
Sakamoto, H.2
Lewis, M.S.3
Anderson, C.W.4
Erickson, J.W.5
Appella, E.6
Xie, D.7
-
152
-
-
0029987031
-
MAT1, cdk7 and cyclin H form a complex which is UV light-sensitive upon association with TFIIH
-
Adamczewski J, Rossignol M, Tassan J-P, Nigg E, Moncollin V, and Egly J-M (1996). MAT1, cdk7 and cyclin H form a complex which is UV light-sensitive upon association with TFIIH. EMBO J 15, 1877-1884.
-
(1996)
EMBO J
, vol.15
, pp. 1877-1884
-
-
Adamczewski, J.1
Rossignol, M.2
Tassan, J.-P.3
Nigg, E.4
Moncollin, V.5
Egly, J.-M.6
-
153
-
-
0028966935
-
Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases
-
Takenaka I, Morin F, Seizinger BR, and Kley N (1995). Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases. J Biol Chem 270, 5405-5411.
-
(1995)
J Biol Chem
, vol.270
, pp. 5405-5411
-
-
Takenaka, I.1
Morin, F.2
Seizinger, B.R.3
Kley, N.4
-
154
-
-
0032540088
-
Regulation of the p53 protein by protein kinase Cα and protein kinase Cξ
-
Youmell M, Park S, Basu S, and Price B (1998). Regulation of the p53 protein by protein kinase Cα and protein kinase Cξ. Biochem Biophys Res Commun 245, 514-518.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 514-518
-
-
Youmell, M.1
Park, S.2
Basu, S.3
Price, B.4
-
155
-
-
0029869392
-
Downregulation of protein kinase C suppresses induction of apoptosis in human prostatic carcinoma cells
-
Rusnak JM, and Lazo JS (1996). Downregulation of protein kinase C suppresses induction of apoptosis in human prostatic carcinoma cells. Exp Cell Res 224, 189-199.
-
(1996)
Exp Cell Res
, vol.224
, pp. 189-199
-
-
Rusnak, J.M.1
Lazo, J.S.2
-
156
-
-
0029993161
-
Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate
-
Milne DM, Mckendrick L, Jardine LJ, Deacon E, Lord JM, and Meek DW (1996). Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate. Oncogene 13, 205-211.
-
(1996)
Oncogene
, vol.13
, pp. 205-211
-
-
Milne, D.M.1
Mckendrick, L.2
Jardine, L.J.3
Deacon, E.4
Lord, J.M.5
Meek, D.W.6
-
157
-
-
0025176921
-
Induction of protein kinase C activity by ultraviolet radiation
-
Matsui M, and DeLeo V (1990). Induction of protein kinase C activity by ultraviolet radiation. Carcinogenesis 11, 229-234.
-
(1990)
Carcinogenesis
, vol.11
, pp. 229-234
-
-
Matsui, M.1
DeLeo, V.2
-
158
-
-
0025376482
-
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2
-
Bischoff J, Friedman P, Marshak D, Prives C, and Beach D (1990). Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc Natl Acad Sci USA 87, 4766-4770.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 4766-4770
-
-
Bischoff, J.1
Friedman, P.2
Marshak, D.3
Prives, C.4
Beach, D.5
-
159
-
-
0025441236
-
p53 interacts with p34cdc2 in mammalian cells: Implications for the cell cycle control and oncogenesis
-
Stürzbecher H-W, Maimets T, Chumakov P, Brain R, Addison C, Simanis V, Rudge K, Philp R, Grimaldi M, Court W, and Jenkins J (1990). p53 interacts with p34cdc2 in mammalian cells: implications for the cell cycle control and oncogenesis. Oncogene 5, 795-801.
-
(1990)
Oncogene
, vol.5
, pp. 795-801
-
-
Stürzbecher, H.-W.1
Maimets, T.2
Chumakov, P.3
Brain, R.4
Addison, C.5
Simanis, V.6
Rudge, K.7
Philp, R.8
Grimaldi, M.9
Court, W.10
Jenkins, J.11
-
160
-
-
0029132301
-
cdk2 kinase phosphorylates serine 315 of human p53 in vitro
-
Price BD, Hughesdavies L, and Park SJ (1995). cdk2 kinase phosphorylates serine 315 of human p53 in vitro. Oncogene 11, 73-80.
-
(1995)
Oncogene
, vol.11
, pp. 73-80
-
-
Price, B.D.1
Hughesdavies, L.2
Park, S.J.3
-
161
-
-
0032495575
-
Fine mapping and regulation of the association of p53 with p34(Cdc2)
-
Wagner P, Fuchs A, Gotz C, Nastainczyk W, and Montenarh M (1998). Fine mapping and regulation of the association of p53 with p34(Cdc2). Oncogene 16, 105-111.
-
(1998)
Oncogene
, vol.16
, pp. 105-111
-
-
Wagner, P.1
Fuchs, A.2
Gotz, C.3
Nastainczyk, W.4
Montenarh, M.5
-
162
-
-
0029003061
-
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
-
Wang Y, and Prives C (1995). Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature 376, 88-91.
-
(1995)
Nature
, vol.376
, pp. 88-91
-
-
Wang, Y.1
Prives, C.2
-
163
-
-
0027296517
-
Regulation of V (D) J recombination activator protein RAG-2 by phosphorylation
-
Lin W-C, and Desiderio S (1993). Regulation of V (D) J recombination activator protein RAG-2 by phosphorylation. Science 260, 953-959.
-
(1993)
Science
, vol.260
, pp. 953-959
-
-
Lin, W.-C.1
Desiderio, S.2
-
164
-
-
0028827848
-
Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase
-
Herzinger T, Funk J, Hillmer K, Eick D, Wolf D, and Kind P (1995). Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase. Oncogene 11, 2151-2156.
-
(1995)
Oncogene
, vol.11
, pp. 2151-2156
-
-
Herzinger, T.1
Funk, J.2
Hillmer, K.3
Eick, D.4
Wolf, D.5
Kind, P.6
-
165
-
-
0029934461
-
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
-
Poon RYC, Jiang W, Toyoshima H, and Hunter T (1996). Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage. J Biol Chem 271, 13283-13291.
-
(1996)
J Biol Chem
, vol.271
, pp. 13283-13291
-
-
Poon, R.Y.C.1
Jiang, W.2
Toyoshima, H.3
Hunter, T.4
-
166
-
-
0030665150
-
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
-
Poon RYC, Chau MS, Yamashita K, and Hunter T (1997). The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res 57, 5168-5178.
-
(1997)
Cancer Res
, vol.57
, pp. 5168-5178
-
-
Poon, R.Y.C.1
Chau, M.S.2
Yamashita, K.3
Hunter, T.4
-
167
-
-
0033617288
-
p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
-
Huang CS, Ma WY, Maxiner A, Sun Y, and Dong ZG (1999). p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 274, 12229-12235.
-
(1999)
J Biol Chem
, vol.274
, pp. 12229-12235
-
-
Huang, C.S.1
Ma, W.Y.2
Maxiner, A.3
Sun, Y.4
Dong, Z.G.5
-
168
-
-
0032936285
-
The double-stranded RNA activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53
-
Cuddihy AR, Li SY, Tam NWN, Wong AHT, Taya Y, Abraham N, Bell JC, and Koromilas AE (1999). The double-stranded RNA activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53. Mol Cell Biol 19, 2475-2484.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2475-2484
-
-
Cuddihy, A.R.1
Li, S.Y.2
Tam, N.W.N.3
Wong, A.H.T.4
Taya, Y.5
Abraham, N.6
Bell, J.C.7
Koromilas, A.E.8
-
169
-
-
0033614407
-
The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro
-
Cuddihy AR, Wong AHT, Tam NWN, Li SY, and Koromilas AE (1999). The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro. Oncogene 18, 2690-2702.
-
(1999)
Oncogene
, vol.18
, pp. 2690-2702
-
-
Cuddihy, A.R.1
Wong, A.H.T.2
Tam, N.W.N.3
Li, S.Y.4
Koromilas, A.E.5
-
170
-
-
0033118933
-
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
-
Shieh SY, Taya Y, and Prives C (1999). DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization. EMBO J 18, 1815-1823.
-
(1999)
EMBO J
, vol.18
, pp. 1815-1823
-
-
Shieh, S.Y.1
Taya, Y.2
Prives, C.3
-
171
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2
-
Unger T, Juven-Gershon T, Moallem E, Berger M, Sionov RV, Lozano G, Oren M, and Haupt Y (1999). Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J 18, 1805-1814.
-
(1999)
EMBO J
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Sionov, R.V.5
Lozano, G.6
Oren, M.7
Haupt, Y.8
-
172
-
-
0029004353
-
Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo
-
Jamal S, and Ziff EB (1995). Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo. Oncogene 10, 2095-2101.
-
(1995)
Oncogene
, vol.10
, pp. 2095-2101
-
-
Jamal, S.1
Ziff, E.B.2
-
173
-
-
0029737462
-
Activation of Raf by ionizing radiation
-
Kasid U, Suy S, Dent P, Ray S, Whiteside TL, and Sturgill TW (1996). Activation of Raf by ionizing radiation. Nature 382, 813-816.
-
(1996)
Nature
, vol.382
, pp. 813-816
-
-
Kasid, U.1
Suy, S.2
Dent, P.3
Ray, S.4
Whiteside, T.L.5
Sturgill, T.W.6
-
174
-
-
0027394710
-
UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase
-
Radler-Pohl A, Sachsenmaier C, Gebel S, Auer HP, Bruder JT, Rapp U, Angel P, Rahmsdorf HJ, and Herrlich P (1993). UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase. EMBO J 12, 1005-1012.
-
(1993)
EMBO J
, vol.12
, pp. 1005-1012
-
-
Radler-Pohl, A.1
Sachsenmaier, C.2
Gebel, S.3
Auer, H.P.4
Bruder, J.T.5
Rapp, U.6
Angel, P.7
Rahmsdorf, H.J.8
Herrlich, P.9
-
175
-
-
0027049804
-
The mammalian ultraviolet response is triggered by activation of Src tyrosine kinase
-
Devary Y, Gottlieb R, Smeal T, and Karin M (1992). The mammalian ultraviolet response is triggered by activation of Src tyrosine kinase. Cell 71, 1081-1091.
-
(1992)
Cell
, vol.71
, pp. 1081-1091
-
-
Devary, Y.1
Gottlieb, R.2
Smeal, T.3
Karin, M.4
-
176
-
-
0030983240
-
Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation
-
Yan Y, Shay JW, Wright WE, and Mumby MC (1997). Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. J Biol Chem 272, 15220-15226.
-
(1997)
J Biol Chem
, vol.272
, pp. 15220-15226
-
-
Yan, Y.1
Shay, J.W.2
Wright, W.E.3
Mumby, M.C.4
-
177
-
-
0000714961
-
Regulation of protein kinase cascades by protein phosphatase 2A
-
Millward T, Zolnierowicz S, and Hemmings B (1999). Regulation of protein kinase cascades by protein phosphatase 2A. Trends Biochem Sci 24, 186-191.
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 186-191
-
-
Millward, T.1
Zolnierowicz, S.2
Hemmings, B.3
-
179
-
-
0030697429
-
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast
-
Li L, Emsting B, Wishart M, Lohse D, and Dixon J (1997). A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. J Biol Chem 272, 29403-29406.
-
(1997)
J Biol Chem
, vol.272
, pp. 29403-29406
-
-
Li, L.1
Emsting, B.2
Wishart, M.3
Lohse, D.4
Dixon, J.5
-
180
-
-
0033593199
-
Role for p300 in stabilization of p53 in the response to DNA damage
-
Yuan ZM, Huang YY, lshiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Yokoyama K, Weichselbaum R, Shi Y, and Kufe D (1999). Role for p300 in stabilization of p53 in the response to DNA damage. J Biol Chem 274, 1883-1886.
-
(1999)
J Biol Chem
, vol.274
, pp. 1883-1886
-
-
Yuan, Z.M.1
Huang, Y.Y.2
Lshiko, T.3
Nakada, S.4
Utsugisawa, T.5
Shioya, H.6
Utsugisawa, Y.7
Yokoyama, K.8
Weichselbaum, R.9
Shi, Y.10
Kufe, D.11
-
181
-
-
0032906633
-
p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage
-
Liu L, Scolnick DM, Trievel RC, Zhang HB, Marmorstein R, Halazonetis TD, and Berger SL (1999). p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol Cell Biol 19, 1202-1209.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1202-1209
-
-
Liu, L.1
Scolnick, D.M.2
Trievel, R.C.3
Zhang, H.B.4
Marmorstein, R.5
Halazonetis, T.D.6
Berger, S.L.7
-
182
-
-
0033533720
-
Function for p300 and not CBP in the apoptotic response to DNA damage
-
Yuan ZM, Huang YY, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Shi Y, Weichselbaum R, and Kufe D (1999). Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene 18, 5714-5717.
-
(1999)
Oncogene
, vol.18
, pp. 5714-5717
-
-
Yuan, Z.M.1
Huang, Y.Y.2
Ishiko, T.3
Nakada, S.4
Utsugisawa, T.5
Shioya, H.6
Utsugisawa, Y.7
Shi, Y.8
Weichselbaum, R.9
Kufe, D.10
-
183
-
-
0029843775
-
ADP-ribosylation of p53 tumor suppressor protein: Mutant but not wild-type p53 is modified
-
Wesierska-Gadek J, Bugajskaschretter A, and Cerni C (1996). ADP-ribosylation of p53 tumor suppressor protein: mutant but not wild-type p53 is modified. J Cell Biochem 62, 90-101.
-
(1996)
J Cell Biochem
, vol.62
, pp. 90-101
-
-
Wesierska-Gadek, J.1
Bugajskaschretter, A.2
Cerni, C.3
-
184
-
-
0030570439
-
ADP-ribosylation of wild-type p53 in vitro: Binding of p53 protein to specific p53 consensus sequence prevents its modification
-
Wesierska-Gadek J, Schmid G, and Cerni C (1996). ADP-ribosylation of wild-type p53 In vitro: binding of p53 protein to specific p53 consensus sequence prevents its modification. Biochem Biophys Res Commun 224, 96-102.
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 96-102
-
-
Wesierska-Gadek, J.1
Schmid, G.2
Cerni, C.3
-
185
-
-
0023903874
-
Effects of 3-aminobenzamide on the rejoining of DNA-strand breaks in mammalian cells exposed to methyl methanesulphonate; role of poly (ADP-ribose) polymerase
-
Ahnström G, and Ljungman M (1988). Effects of 3-aminobenzamide on the rejoining of DNA-strand breaks in mammalian cells exposed to methyl methanesulphonate; role of poly (ADP-ribose) polymerase. Mutat Res 194, 17-22.
-
(1988)
Mutat Res
, vol.194
, pp. 17-22
-
-
Ahnström, G.1
Ljungman, M.2
-
186
-
-
0032939088
-
Poly ADP-ribosylation: A DNA break signal mechanism
-
Althaus FR, Kleczkowska HE, Malanga M, Müntener CR, Pleschke JM, Ebner M, and Auer B (1999). Poly ADP-ribosylation: a DNA break signal mechanism. Mol Cell Biochem 193, 5-11.
-
(1999)
Mol Cell Biochem
, vol.193
, pp. 5-11
-
-
Althaus, F.R.1
Kleczkowska, H.E.2
Malanga, M.3
Müntener, C.R.4
Pleschke, J.M.5
Ebner, M.6
Auer, B.7
-
187
-
-
0032518339
-
DNA repair: PARP - Another guardian angel?
-
Jeggo PA (1997). DNA repair: PARP - another guardian angel? Curr Biol 8, R49-R51.
-
(1997)
Curr Biol
, vol.8
-
-
Jeggo, P.A.1
-
188
-
-
0032533856
-
Functional interactions of p53 with poly (ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: Covalent poly (ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the Mr 85,000 proteolytic fragment
-
Kumari SR, Mendoza-Alvarez H, and Alvarez-Gonzalez R (1998). Functional interactions of p53 with poly (ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly (ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the Mr 85,000 proteolytic fragment. Cancer Res 58, 5075-5078.
-
(1998)
Cancer Res
, vol.58
, pp. 5075-5078
-
-
Kumari, S.R.1
Mendoza-Alvarez, H.2
Alvarez-Gonzalez, R.3
-
189
-
-
0030614626
-
Modulation of (±)-anti-BPDE mediated p53 accumulation by inhibitors of protein kinase C and poly(ADP-ribose) polymerase
-
Venkatachalam S, Denissenko M, and Wani AA (1997). Modulation of (±)-anti-BPDE mediated p53 accumulation by inhibitors of protein kinase C and poly(ADP-ribose) polymerase. Oncogene 14, 801-809.
-
(1997)
Oncogene
, vol.14
, pp. 801-809
-
-
Venkatachalam, S.1
Denissenko, M.2
Wani, A.A.3
-
190
-
-
0030761351
-
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the posttranslational activation of p53 protein involving poly (ADP-ribose) polymerase
-
Vaziri H, West MD, Allsopp RC, Davison TS, Wu YS, Arrowsmith CH, Poirier GG, and Benchimol S (1997). ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the posttranslational activation of p53 protein involving poly (ADP-ribose) polymerase. EMBO J 16, 6018-6033.
-
(1997)
EMBO J
, vol.16
, pp. 6018-6033
-
-
Vaziri, H.1
West, M.D.2
Allsopp, R.C.3
Davison, T.S.4
Wu, Y.S.5
Arrowsmith, C.H.6
Poirier, G.G.7
Benchimol, S.8
-
191
-
-
0032919454
-
Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts
-
Wesierska-Gadek J, Wang ZQ, and Schmid G (1999). Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts. Cancer Res 59, 28-34.
-
(1999)
Cancer Res
, vol.59
, pp. 28-34
-
-
Wesierska-Gadek, J.1
Wang, Z.Q.2
Schmid, G.3
-
192
-
-
0033135756
-
Poly (ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells
-
Simbulan-Rosenthal CM, Rosenthal DS, Luo RB, and Smulson ME (1999). Poly (ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells. Cancer Res 59, 2190-2194.
-
(1999)
Cancer Res
, vol.59
, pp. 2190-2194
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Luo, R.B.3
Smulson, M.E.4
-
193
-
-
0032481112
-
Poly (ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation
-
Wang XJ, Ohnishi K, Takahashi A, and Ohnishi T (1998). Poly (ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation. Oncogene 17, 2819-2825.
-
(1998)
Oncogene
, vol.17
, pp. 2819-2825
-
-
Wang, X.J.1
Ohnishi, K.2
Takahashi, A.3
Ohnishi, T.4
-
194
-
-
0029099358
-
Involvement of NAD-poly (ADP-ribose) metabolism in p53 regulation and its consequences
-
Whitacre CM, Hashimoto H, Tsai ML, Chatterjee S, Berger SJ, and Berger NA (1995). Involvement of NAD-poly (ADP-ribose) metabolism in p53 regulation and its consequences. Cancer Res 55, 3697-3701.
-
(1995)
Cancer Res
, vol.55
, pp. 3697-3701
-
-
Whitacre, C.M.1
Hashimoto, H.2
Tsai, M.L.3
Chatterjee, S.4
Berger, S.J.5
Berger, N.A.6
-
195
-
-
0033614370
-
Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max
-
Kirch HC, Flaswinkel S, Rumpf H, Brockmann D, and Esche H (1999). Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max. Oncogene 18, 2728-2738.
-
(1999)
Oncogene
, vol.18
, pp. 2728-2738
-
-
Kirch, H.C.1
Flaswinkel, S.2
Rumpf, H.3
Brockmann, D.4
Esche, H.5
-
196
-
-
0029813256
-
YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1a cooperate to amplify p53 promoter activity
-
Furlong EEM, Rein T, and Martin F (1996). YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity. Mol Cell Biol 16, 5933-5945.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5933-5945
-
-
Furlong, E.E.M.1
Rein, T.2
Martin, F.3
-
197
-
-
0028809870
-
Loss of p53 function through PAX-mediated transcriptional repression
-
Stuart E, Haffner R, Oren M, and Gruss P (1995). Loss of p53 function through PAX-mediated transcriptional repression. EMBO J 14, 5638-5645.
-
(1995)
EMBO J
, vol.14
, pp. 5638-5645
-
-
Stuart, E.1
Haffner, R.2
Oren, M.3
Gruss, P.4
-
198
-
-
0028828412
-
Transcriptional repression of p53 by human T-cell leukemia virus type I tax protein
-
Uittenbogaard MN, Giebler HA, Reisman D, and Nyborg JK (1995). Transcriptional repression of p53 by human T-cell leukemia virus type I tax protein. J Biol Chem 270, 28503-28506.
-
(1995)
J Biol Chem
, vol.270
, pp. 28503-28506
-
-
Uittenbogaard, M.N.1
Giebler, H.A.2
Reisman, D.3
Nyborg, J.K.4
-
199
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53-dependent
-
Schreiber M, Kolbus A, Piu F, Szabowski A, Möhle-Steinlein U, Tian JM, Karin M, Angel P, and Wagner EF (1999). Control of cell cycle progression by c-Jun is p53-dependent. Genes Dev 13, 607-619.
-
(1999)
Genes Dev
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
Kolbus, A.2
Piu, F.3
Szabowski, A.4
Möhle-Steinlein, U.5
Tian, J.M.6
Karin, M.7
Angel, P.8
Wagner, E.F.9
-
200
-
-
0029049242
-
Wild-type p53 regulates its own transcription in a cell-type specific manner
-
Hudson JM, Frade R, and Bareli M (1995). Wild-type p53 regulates its own transcription in a cell-type specific manner. DNA Cell Biol 14, 759-766.
-
(1995)
DNA Cell Biol
, vol.14
, pp. 759-766
-
-
Hudson, J.M.1
Frade, R.2
Bareli, M.3
-
201
-
-
0029007316
-
Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression
-
Sun XG, Shimizu H, and Yamamoto KI (1995). Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol Cell Biol 15, 4489-4496.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4489-4496
-
-
Sun, X.G.1
Shimizu, H.2
Yamamoto, K.I.3
-
202
-
-
0030983331
-
Participation of the human p53 3′ UTR in translational repression and activation following gamma-irradiation
-
Fu LN, and Benchimol S (1997). Participation of the human p53 3′ UTR in translational repression and activation following gamma-irradiation. EMBO J 16, 4117-4125.
-
(1997)
EMBO J
, vol.16
, pp. 4117-4125
-
-
Fu, L.N.1
Benchimol, S.2
-
203
-
-
0029115918
-
Negative feedback regulation of wild-type p53 biosynthesis
-
Mosner J, Mummenbrauer T, Bauer C, Sczakiel G, Grosse F, and Deppert W (1995). Negative feedback regulation of wild-type p53 biosynthesis. EMBO J 14, 4442-4449.
-
(1995)
EMBO J
, vol.14
, pp. 4442-4449
-
-
Mosner, J.1
Mummenbrauer, T.2
Bauer, C.3
Sczakiel, G.4
Grosse, F.5
Deppert, W.6
-
204
-
-
0029766553
-
Translational regulation of human p53 gene expression
-
Fu LN, Minden MD, and Benchimol S (1996). Translational regulation of human p53 gene expression. EMBO J 15, 4392-4401.
-
(1996)
EMBO J
, vol.15
, pp. 4392-4401
-
-
Fu, L.N.1
Minden, M.D.2
Benchimol, S.3
-
205
-
-
0033616620
-
Regulation of p53 expression by thymidylate synthase
-
Ju JF, Pedersen-Lane J, Maley F, and Chu E (1999). Regulation of p53 expression by thymidylate synthase. Proc Natl Acad Sci USA 96, 3769-3774.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3769-3774
-
-
Ju, J.F.1
Pedersen-Lane, J.2
Maley, F.3
Chu, E.4
-
207
-
-
0031724593
-
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
-
Freedman DA, and Levine AJ (1998). Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol Cell Biol 18, 7288-7293.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7288-7293
-
-
Freedman, D.A.1
Levine, A.J.2
-
208
-
-
0030665146
-
Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53
-
Mayo LD, Turchi JJ, and Berberich SJ (1997). Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53. Cancer Res 57, 5013-5016.
-
(1997)
Cancer Res
, vol.57
, pp. 5013-5016
-
-
Mayo, L.D.1
Turchi, J.J.2
Berberich, S.J.3
-
209
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19(Arf), interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz J, SchreiberAgus N, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, CordonCardo C, and DePinho RA (1998). The Ink4a tumor suppressor gene product, p19(Arf), interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92, 713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
SchreiberAgus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
CordonCardo, C.11
DePinho, R.A.12
-
210
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang YP, Xiong Y, and Yarbrough WG (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92, 725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.P.1
Xiong, Y.2
Yarbrough, W.G.3
-
211
-
-
0032169516
-
The alternative product from the human CDKN2a locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
-
Stott FJ, Bates S, James MC, McConnell BB, Starborg M, Brookes S, Palmero I, Ryan K, Hara E, Vousden KH, and Peters G (1998). The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2. EMBO J 17, 5001-5014.
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
212
-
-
0033521621
-
ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
-
ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. EMBO J 18, 22-27.
-
(1999)
EMBO J
, vol.18
, pp. 22-27
-
-
Honda, R.1
Yasuda, H.2
-
213
-
-
0030728468
-
ARF
-
ARF. Cell 91, 649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.3
Quelle, D.4
Downing, J.5
Ashum, R.6
Grosveld, G.7
Sherr, C.8
-
214
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, and Roussel MF (1998). Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev 12, 2424-2433.
-
(1998)
Genes Dev
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
Kamijo, T.4
Cleveland, J.L.5
Sherr, C.J.6
Roussel, M.F.7
-
216
-
-
0032504783
-
ARF links the tumour suppressors RB and p53
-
ARF links the tumour suppressors RB and p53. Nature 395, 124-125.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.A.3
Stott, F.4
Peters, G.5
Ludwig, R.L.6
Vousden, K.H.7
-
217
-
-
0032146795
-
ARF tumor suppressor
-
ARF tumor suppressor. Genes Dev 12, 2434-2442.
-
(1998)
Genes Dev
, vol.12
, pp. 2434-2442
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Shieh, S.Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Prives, C.7
Roussel, M.F.8
Sherr, C.J.9
Lowe, S.W.10
-
218
-
-
0033569423
-
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
-
Schmitt C, McCurrach M, de Stanchina E, Wallace-Brodeur R, and Lowe S (1999). INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev 13, 2670-2677.
-
(1999)
Genes Dev
, vol.13
, pp. 2670-2677
-
-
Schmitt, C.1
McCurrach, M.2
De Stanchina, E.3
Wallace-Brodeur, R.4
Lowe, S.5
-
219
-
-
0031771497
-
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and downregulated by wild-type p53
-
Robertson KD, and Jones PA (1998). The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and downregulated by wild-type p53. Mol Cell Biol 18, 6457-6473.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6457-6473
-
-
Robertson, K.D.1
Jones, P.A.2
-
220
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh SY, Ikeda M, Taya Y, and Prives C (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
221
-
-
0031435944
-
DNA damage induces phosphorytation of the amino terminus of p53
-
Siliciano JD, Canman CE, Taya Y, Sakaguchi K, Appella E, and Kastan MB (1997). DNA damage induces phosphorytation of the amino terminus of p53. Genes Dev 11, 3471-3481.
-
(1997)
Genes Dev
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
222
-
-
0025203803
-
Subcellular distribution of the p53 protein during the cell cycle of Balb/c 3T3 cells
-
Shaulsky G, Ben-Ze'ev A, and Rotter V (1990). Subcellular distribution of the p53 protein during the cell cycle of Balb/c 3T3 cells. Oncogene 5, 1707-1711.
-
(1990)
Oncogene
, vol.5
, pp. 1707-1711
-
-
Shaulsky, G.1
Ben-Ze'ev, A.2
Rotter, V.3
-
223
-
-
0029827769
-
Cell cycle-dependent regulation of nuclear p53 traffic occurs in one subclass of human tumor cells and in untransformed cells
-
David-Pfeuty T, Chakrani F, Ory K, and Nouviandooghe Y (1996). Cell cycle-dependent regulation of nuclear p53 traffic occurs in one subclass of human tumor cells and in untransformed cells. Cell Growth Differ 7, 1211-1225.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1211-1225
-
-
David-Pfeuty, T.1
Chakrani, F.2
Ory, K.3
Nouviandooghe, Y.4
-
224
-
-
0030722533
-
Intracellular localization of p53 tumor suppressor protein in gamma-irradiated cells is cell cycle regulated and determined by the nucleus
-
Komarova EA, Zelnick CR, Chin D, Zeremski M, Gleiberman AS, Bacus SS, and Gudkov AV (1997). Intracellular localization of p53 tumor suppressor protein in gamma-irradiated cells is cell cycle regulated and determined by the nucleus. Cancer Res 57, 5217-5220.
-
(1997)
Cancer Res
, vol.57
, pp. 5217-5220
-
-
Komarova, E.A.1
Zelnick, C.R.2
Chin, D.3
Zeremski, M.4
Gleiberman, A.S.5
Bacus, S.S.6
Gudkov, A.V.7
-
225
-
-
0032584666
-
Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein
-
Liang SH, Hong D, and Clarke MF (1998). Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein. J Biol Chem 273, 19817-19821.
-
(1998)
J Biol Chem
, vol.273
, pp. 19817-19821
-
-
Liang, S.H.1
Hong, D.2
Clarke, M.F.3
-
226
-
-
0033602407
-
The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal
-
Liang SH, and Clarke MF (1999). The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal. Oncogene 18, 2163-2166.
-
(1999)
Oncogene
, vol.18
, pp. 2163-2166
-
-
Liang, S.H.1
Clarke, M.F.2
-
227
-
-
0032755396
-
A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain
-
Liang S-H, and Clarke M (1999). A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain. J Biol Chem 274, 32699-32703.
-
(1999)
J Biol Chem
, vol.274
, pp. 32699-32703
-
-
Liang, S.-H.1
Clarke, M.2
-
228
-
-
0030964105
-
Nucleocytoplasmic transport: Signals, mechanisms and regulation
-
Nigg E (1997). Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386, 779-787.
-
(1997)
Nature
, vol.386
, pp. 779-787
-
-
Nigg, E.1
-
229
-
-
0033178866
-
Getting across the nuclear pore complex
-
Talcott B, and Moore M (1999). Getting across the nuclear pore complex. Trends Cell Biol 9, 312-318.
-
(1999)
Trends Cell Biol
, vol.9
, pp. 312-318
-
-
Talcott, B.1
Moore, M.2
-
230
-
-
0033152544
-
Transport pathways of macromolecules between the nucleus and the cytoplasm
-
Adam S (1999). Transport pathways of macromolecules between the nucleus and the cytoplasm. Curr Opin Cell Biol 11, 402-406.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 402-406
-
-
Adam, S.1
-
231
-
-
0033559256
-
A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, and Wahl GM (1999). A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J 18, 1660-1672.
-
(1999)
EMBO J
, vol.18
, pp. 1660-1672
-
-
Stommel, J.M.1
Marchenko, N.D.2
Jimenez, G.S.3
Moll, U.M.4
Hope, T.J.5
Wahl, G.M.6
-
232
-
-
0026694826
-
Two distinct mechanism alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll U, Riou G, and Levine A (1992). Two distinct mechanism alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 92, 7262-7266.
-
(1992)
Proc Natl Acad Sci USA
, vol.92
, pp. 7262-7266
-
-
Moll, U.1
Riou, G.2
Levine, A.3
-
233
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll U, LaQuaglia M, Bernard J, and Riou G (1995). Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci USA 92, 4407-4411.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.1
LaQuaglia, M.2
Bernard, J.3
Riou, G.4
-
234
-
-
0028364494
-
I-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle
-
Ryan J, Prochowink E, Gottlieb C, Apel I, Merino R, Nuñez G, and Clarke M (1994). c-myc and bcI-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle. Proc Natl Acad Sci USA 91, 5878-5882.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5878-5882
-
-
Ryan, J.1
Prochowink, E.2
Gottlieb, C.3
Apel, I.4
Merino, R.5
Nuñez, G.6
Clarke, M.7
-
235
-
-
15444344269
-
BcI-2 inhibits p53 nuclear import following DNA damage
-
Beham A, Marin MC, Fernandez A, Herrmann J, Brisbay S, Tari AM, LopezBerestein G, Lozano G, Sarkiss M, and McDonnell TJ (1997). BcI-2 inhibits p53 nuclear import following DNA damage. Oncogene 15, 2767-2772.
-
(1997)
Oncogene
, vol.15
, pp. 2767-2772
-
-
Beham, A.1
Marin, M.C.2
Fernandez, A.3
Herrmann, J.4
Brisbay, S.5
Tari, A.M.6
LopezBerestein, G.7
Lozano, G.8
Sarkiss, M.9
McDonnell, T.J.10
-
236
-
-
85047673784
-
Regulation of transcription factor localization: Fine-tuning of gene expression
-
A
-
Vandromme M, Guuthier-Rouviére C, and Lamb F, A (1996). Regulation of transcription factor localization: fine-tuning of gene expression. Trends Biol Sci 21, 59-64.
-
(1996)
Trends Biol Sci
, vol.21
, pp. 59-64
-
-
Vandromme, M.1
Guuthier-Rouviére, C.2
Lamb, F.3
-
237
-
-
0032481111
-
Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation
-
Hengstermann A, Whitaker NJ, Zimmer D, Zentgraf H, and Scheffner M (1998). Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation. Oncogene 17, 2933-2941.
-
(1998)
Oncogene
, vol.17
, pp. 2933-2941
-
-
Hengstermann, A.1
Whitaker, N.J.2
Zimmer, D.3
Zentgraf, H.4
Scheffner, M.5
-
238
-
-
0033522143
-
DNA damage induced p53 stabilization: No indication for an involvement of p53 phosphorylation
-
Blattner C, Tobiasch E, Litten M, Rahmsdorf HJ, and Herrlich P (1999). DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation. Oncogene 18, 1723-1732.
-
(1999)
Oncogene
, vol.18
, pp. 1723-1732
-
-
Blattner, C.1
Tobiasch, E.2
Litten, M.3
Rahmsdorf, H.J.4
Herrlich, P.5
-
239
-
-
0033020147
-
Regulation of p53 function and stability by phosphorylation
-
Ashcroft M, Kubbutat MHG, and Vousden KH (1999). Regulation of p53 function and stability by phosphorylation. Mol Cell Biol 19, 1751-1758.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1751-1758
-
-
Ashcroft, M.1
Kubbutat, M.H.G.2
Vousden, K.H.3
-
240
-
-
0032254350
-
The phosphotase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation
-
Visintin R, Craig K, Hwang E, Prinz S, Tyers M, and Amon A (1998). The phosphotase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell 2, 709-718.
-
(1998)
Mol Cell
, vol.2
, pp. 709-718
-
-
Visintin, R.1
Craig, K.2
Hwang, E.3
Prinz, S.4
Tyers, M.5
Amon, A.6
-
241
-
-
0028845158
-
Small peptides activate the latent sequence-specific DNA binding function of p53
-
Hupp T, Sparks A, and Lane D (1995). Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 83, 237-245.
-
(1995)
Cell
, vol.83
, pp. 237-245
-
-
Hupp, T.1
Sparks, A.2
Lane, D.3
-
242
-
-
0038298110
-
An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs
-
Lain S, Midgley C, Sparks A, Lane EB, and Lane DP (1999). An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs. Exp Cell Res 248, 457-472.
-
(1999)
Exp Cell Res
, vol.248
, pp. 457-472
-
-
Lain, S.1
Midgley, C.2
Sparks, A.3
Lane, E.B.4
Lane, D.P.5
-
243
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
Jayaraman L, Murthy KGK, Zhu C, Curran T, Xanthoudakis S, and Prives C (1997). Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev 11, 558-570.
-
(1997)
Genes Dev
, vol.11
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.K.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
244
-
-
0032520175
-
High mobility group protein-1 (HMG-1) is a unique activator of p53
-
Jayaraman L, Moorthy NC, Murthy KGK, Manley JL, Bustin M, and Prives C (1998). High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes Dev 12, 462-472.
-
(1998)
Genes Dev
, vol.12
, pp. 462-472
-
-
Jayaraman, L.1
Moorthy, N.C.2
Murthy, K.G.K.3
Manley, J.L.4
Bustin, M.5
Prives, C.6
-
245
-
-
0030996361
-
Synergistic activation of transcription by CBP and p53
-
Gu W, Shi XL, and Roeder RG (1997). Synergistic activation of transcription by CBP and p53. Nature 387, 819-823.
-
(1997)
Nature
, vol.387
, pp. 819-823
-
-
Gu, W.1
Shi, X.L.2
Roeder, R.G.3
-
246
-
-
0030973238
-
Binding and modulation of p53 by p300/CBP coactivators
-
Lill NL, Grossman SR, Ginsberg D, DeCaprio J, and Livingston DM (1997). Binding and modulation of p53 by p300/CBP coactivators. Nature 387, 823-827.
-
(1997)
Nature
, vol.387
, pp. 823-827
-
-
Lill, N.L.1
Grossman, S.R.2
Ginsberg, D.3
DeCaprio, J.4
Livingston, D.M.5
-
247
-
-
0030880936
-
CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein
-
Scolnick DM, Chehab NH, Stavridi ES, Lien MC, Caruso L, Moran E, Berger SL, and Halazonetis TD (1997). CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein. Cancer Res 57, 3693-3696.
-
(1997)
Cancer Res
, vol.57
, pp. 3693-3696
-
-
Scolnick, D.M.1
Chehab, N.H.2
Stavridi, E.S.3
Lien, M.C.4
Caruso, L.5
Moran, E.6
Berger, S.L.7
Halazonetis, T.D.8
-
248
-
-
0031587821
-
Recruitment of p300/CBP in p53-dependent signal pathways
-
Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, and Kelly K (1997). Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89, 1175-1184.
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.S.5
Kelly, K.6
-
249
-
-
0027522235
-
Cooperative DNA binding of p53 with TFIID (TBP) - A possible mechanism for transcriptional activation
-
Chen XB, Farmer G, Zhu H, Prywes R, and Prives C (1993). Cooperative DNA binding of p53 with TFIID (TBP) - a possible mechanism for transcriptional activation. Genes Dev 7, 1837-1849.
-
(1993)
Genes Dev
, vol.7
, pp. 1837-1849
-
-
Chen, X.B.1
Farmer, G.2
Zhu, H.3
Prywes, R.4
Prives, C.5
-
250
-
-
0027451298
-
p53 binds to the TATA-binding protein-TATA complexes
-
Martin D, Munoz R, Subler M, and Deb S (1993). p53 binds to the TATA-binding protein-TATA complexes. J Biol Chem 268, 13062-13067.
-
(1993)
J Biol Chem
, vol.268
, pp. 13062-13067
-
-
Martin, D.1
Munoz, R.2
Subler, M.3
Deb, S.4
-
251
-
-
0027983521
-
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53
-
Xiao H, Pearson A, Coulombe B, Truant R, Zhang S, Regier JL, Triezenberg SJ, Reinberg D, Flores O, Ingles CJ, and Greenblatt J (1994). Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol Cell Biol 14, 7013-7024.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7013-7024
-
-
Xiao, H.1
Pearson, A.2
Coulombe, B.3
Truant, R.4
Zhang, S.5
Regier, J.L.6
Triezenberg, S.J.7
Reinberg, D.8
Flores, O.9
Ingles, C.J.10
Greenblatt, J.11
-
252
-
-
0029880959
-
Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations
-
Léveillard T, Andera L, Bissonnette N, Schaeffer L, Bracco L, Egly JM, and Wasylyk B (1996). Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J 15, 1615-1624.
-
(1996)
EMBO J
, vol.15
, pp. 1615-1624
-
-
Léveillard, T.1
Andera, L.2
Bissonnette, N.3
Schaeffer, L.4
Bracco, L.5
Egly, J.M.6
Wasylyk, B.7
-
253
-
-
0029943611
-
Functional interaction between p53, the TATA-binding protein (TBP), and TBP-associated factors in vivo
-
Farmer G, Colgan J, Nakatani Y, Manley JL, and Prives C (1996). Functional interaction between p53, the TATA-binding protein (TBP), and TBP-associated factors in vivo. Mol Cell Biol 16, 4295-4304.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4295-4304
-
-
Farmer, G.1
Colgan, J.2
Nakatani, Y.3
Manley, J.L.4
Prives, C.5
-
254
-
-
0029092670
-
p53 and Sp1 interact and cooperate in the tumor necrosis factor-induced transcriptional activation of the HIV-1 long terminal repeat
-
Gualberto A, and Baldwin AS (1995). p53 and Sp1 interact and cooperate in the tumor necrosis factor-induced transcriptional activation of the HIV-1 long terminal repeat. J Biol Chem 270, 19680-19683.
-
(1995)
J Biol Chem
, vol.270
, pp. 19680-19683
-
-
Gualberto, A.1
Baldwin, A.S.2
-
255
-
-
0033197703
-
A novel cofactor for p300 that regulates the p53 response
-
Shikama N, Lee CW, France S, Delavaine L, Lyon J, Krstic-Demonacos M, and La Thangue NB (1999). A novel cofactor for p300 that regulates the p53 response. Mol Cell 4, 365-376.
-
(1999)
Mol Cell
, vol.4
, pp. 365-376
-
-
Shikama, N.1
Lee, C.W.2
France, S.3
Delavaine, L.4
Lyon, J.5
Krstic-Demonacos, M.6
La Thangue, N.B.7
-
256
-
-
0033621189
-
The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53
-
Gobert C, Skladanowski A, and Larsen AK (1999). The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53. Proc Natl Acad Sci USA 96, 10355-10360.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10355-10360
-
-
Gobert, C.1
Skladanowski, A.2
Larsen, A.K.3
-
257
-
-
0030088026
-
Activation of mammalian gene expression by the UV component of sunlight - From models to reality
-
Tyrell R (1996). Activation of mammalian gene expression by the UV component of sunlight - from models to reality. BioEssays 18, 139-148.
-
(1996)
BioEssays
, vol.18
, pp. 139-148
-
-
Tyrell, R.1
-
258
-
-
0032954928
-
Transcriptional cross talk between NF-kappaB and p53
-
Webster GA, and Perkins ND (1999). Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol 19, 3485-3495.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
259
-
-
0033593217
-
CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling
-
Wadgaonkar R, Phelps KM, Haque Z, Williams AJ, Silverman ES, and Collins T (1999). CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling. J Biol Chem 274, 1879-1882.
-
(1999)
J Biol Chem
, vol.274
, pp. 1879-1882
-
-
Wadgaonkar, R.1
Phelps, K.M.2
Haque, Z.3
Williams, A.J.4
Silverman, E.S.5
Collins, T.6
-
260
-
-
0033524942
-
A viral mechanism for inhibition of p300 and PCAF acetyl transferase activity
-
Chakravarti D, Ogryzko V, Kao H-Y, Nash A, Chen H, Nakatani Y, and Evans R (1999). A viral mechanism for inhibition of p300 and PCAF acetyl transferase activity. Cell 96, 393-403.
-
(1999)
Cell
, vol.96
, pp. 393-403
-
-
Chakravarti, D.1
Ogryzko, V.2
Kao, H.-Y.3
Nash, A.4
Chen, H.5
Nakatani, Y.6
Evans, R.7
-
261
-
-
0033525094
-
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A
-
Hamamori Y, Sartorelli V, Ogryzko V, Puri P, Wu H-Y, Wang Y, Nakatani Y, and Kedes L (1999). Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell 96, 405-413.
-
(1999)
Cell
, vol.96
, pp. 405-413
-
-
Hamamori, Y.1
Sartorelli, V.2
Ogryzko, V.3
Puri, P.4
Wu, H.-Y.5
Wang, Y.6
Nakatani, Y.7
Kedes, L.8
-
262
-
-
0029163015
-
Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents
-
Girinsky T, Koumenis C, Graeber TG, Peehl DM, and Giaccia AJ (1995). Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents. Cancer Res 55, 3726-3731.
-
(1995)
Cancer Res
, vol.55
, pp. 3726-3731
-
-
Girinsky, T.1
Koumenis, C.2
Graeber, T.G.3
Peehl, D.M.4
Giaccia, A.J.5
-
263
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R, and Wahl GM (1998). ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr Biol 8, 145-155.
-
(1998)
Curr Biol
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
Hope, T.J.4
Klemm, M.5
Jaenisch, R.6
Wahl, G.M.7
-
264
-
-
0033554553
-
Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light
-
Meyer KM, Hess SM, Tlsty TD, and Leadon SA (1999). Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light. Oncogene 18, 5795-5805.
-
(1999)
Oncogene
, vol.18
, pp. 5795-5805
-
-
Meyer, K.M.1
Hess, S.M.2
Tlsty, T.D.3
Leadon, S.A.4
-
265
-
-
0033600897
-
Arsenic disrupts cellular levels of p53 and mdm2: A potential mechanism of carcinogenesis
-
Hamadeh HK, Vargas M, Lee E, and Menzel DB (1999). Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis. Biochem Biophys Res Commun 263, 446-449.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 446-449
-
-
Hamadeh, H.K.1
Vargas, M.2
Lee, E.3
Menzel, D.B.4
-
266
-
-
0039136305
-
Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells
-
Méplan C, Mann K, and Hainaut P (1999). Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. J Biol Chem 44, 31663-31670.
-
(1999)
J Biol Chem
, vol.44
, pp. 31663-31670
-
-
Méplan, C.1
Mann, K.2
Hainaut, P.3
-
267
-
-
0018769971
-
Simian virus-transformed cells express new species of proteins precipitable by anti-simian virus 40 tumor serum
-
Kress M, May E, Cassingena R, and May P (1979). Simian virus-transformed cells express new species of proteins precipitable by anti-simian virus 40 tumor serum. J Virol 31, 472-483.
-
(1979)
J Virol
, vol.31
, pp. 472-483
-
-
Kress, M.1
May, E.2
Cassingena, R.3
May, P.4
-
268
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
Lane D, and Crawford L (1979). T antigen is bound to a host protein in SV40-transformed cells. Nature 278, 261-263.
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.1
Crawford, L.2
-
269
-
-
0018760324
-
Characterization of a 54K dalton cellular SV40 tumour antigen present in SV40 transformed cells and uninfected embryonal carcinoma cells
-
Linzer D, and Levine A (1979). Characterization of a 54K dalton cellular SV40 tumour antigen present in SV40 transformed cells and uninfected embryonal carcinoma cells. Cell 17, 43-52.
-
(1979)
Cell
, vol.17
, pp. 43-52
-
-
Linzer, D.1
Levine, A.2
-
270
-
-
0029964158
-
A reversible, p53-dependent G(0)/G(1) cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
-
Linke SP, Clarkin KC, Dileonardo A, Tsou A, and Wahl GM (1996). A reversible, p53-dependent G(0)/G(1) cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev 10, 934-947.
-
(1996)
Genes Dev
, vol.10
, pp. 934-947
-
-
Linke, S.P.1
Clarkin, K.C.2
Dileonardo, A.3
Tsou, A.4
Wahl, G.M.5
-
271
-
-
0030785521
-
Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response
-
Eller MS, Maeda T, Magnoni C, Atwal D, and Gilchrest BA (1997). Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response. Proc Natl Acad Sci USA 94, 12627-12632.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12627-12632
-
-
Eller, M.S.1
Maeda, T.2
Magnoni, C.3
Atwal, D.4
Gilchrest, B.A.5
-
272
-
-
0027298576
-
Induction of cellular p53 activity by DNA-damaging agents and growth arrest
-
Zhan Q, Carrier F, and Fornace A (1993). Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 13, 4242-4250.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4242-4250
-
-
Zhan, Q.1
Carrier, F.2
Fornace, A.3
-
273
-
-
0028110809
-
Hypoxia induces accumulation of p53 protein, but activation of a G(1)-phase checkpoint by low-oxygen conditions is independent of p53 status
-
Graeber TG, Peterson JF, Tsai M, Monica K, Fornace AJ, and Giaccia AJ (1994). Hypoxia induces accumulation of p53 protein, but activation of a G(1)-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol 14, 6264-6277.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
Monica, K.4
Fornace, A.J.5
Giaccia, A.J.6
-
274
-
-
0029912852
-
Flavonoids activate wild-type p53
-
Plaumann B, Fritsche M, Rimpler H, Brandner G, and Hess RD (1996). Flavonoids activate wild-type p53. Oncogene 13, 1605-1614.
-
(1996)
Oncogene
, vol.13
, pp. 1605-1614
-
-
Plaumann, B.1
Fritsche, M.2
Rimpler, H.3
Brandner, G.4
Hess, R.D.5
-
275
-
-
0032522798
-
Antioxidant action via p53-mediated apoptosis
-
Liu M, Pelling J, Ju J, Chu E, and Brash D (1998). Antioxidant action via p53-mediated apoptosis. Cancer Res 58, 1723-1729.
-
(1998)
Cancer Res
, vol.58
, pp. 1723-1729
-
-
Liu, M.1
Pelling, J.2
Ju, J.3
Chu, E.4
Brash, D.5
-
276
-
-
0027212267
-
Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents
-
Tishler R, Calderwood S, Coleman C, and Price B (1993). Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. Cancer Res 53, 2212-2216.
-
(1993)
Cancer Res
, vol.53
, pp. 2212-2216
-
-
Tishler, R.1
Calderwood, S.2
Coleman, C.3
Price, B.4
-
277
-
-
0028131873
-
p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cells lines
-
Matsumoto H, Shimura M, Omatsu T, Okaichi K, Majima H, and Ohnishi T (1994). p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cells lines. Cancer Lett 87, 39-46.
-
(1994)
Cancer Lett
, vol.87
, pp. 39-46
-
-
Matsumoto, H.1
Shimura, M.2
Omatsu, T.3
Okaichi, K.4
Majima, H.5
Ohnishi, T.6
-
278
-
-
0032546272
-
p53-dependent induction of WAF1 by cold shock in human glioma cells
-
Ohnishi T, Wang X, Ohnishi K, and Takahashi A (1998). p53-dependent induction of WAF1 by cold shock in human glioma cells. Oncogene 16, 1507-1511.
-
(1998)
Oncogene
, vol.16
, pp. 1507-1511
-
-
Ohnishi, T.1
Wang, X.2
Ohnishi, K.3
Takahashi, A.4
-
279
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B
-
Debbas M, and White E (1993). Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B. Genes Dev 7, 546-554.
-
(1993)
Genes Dev
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
280
-
-
0033082231
-
Rb regulates the stability and the apoptotic function of p53 via MDM2
-
Hsieh J-K, Chan F. O'Connor D, Mittnacht S, Zhong S, and Lu X (1999). Rb regulates the stability and the apoptotic function of p53 via MDM2. Cell 3, 181-193.
-
(1999)
Cell
, vol.3
, pp. 181-193
-
-
Hsieh, J.-K.1
Chan, F.2
O'Connor, D.3
Mittnacht, S.4
Zhong, S.5
Lu, X.6
-
281
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal Phosphorylation and apoptosis in response to UV irradiation
-
Bulavin D, Saito S, Hollander M, Sakaguchi K, Anderson C, Appella E, and Fornace A (1999). Phosphorylation of human p53 by p38 kinase coordinates N-terminal Phosphorylation and apoptosis in response to UV irradiation. EMBO J 18, 6845-6854.
-
(1999)
EMBO J
, vol.18
, pp. 6845-6854
-
-
Bulavin, D.1
Saito, S.2
Hollander, M.3
Sakaguchi, K.4
Anderson, C.5
Appella, E.6
Fornace, A.7
-
282
-
-
0033598754
-
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
-
Chehab NH, Malikzay A, Stavridi ES, and Halazonetis TD (1999). Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc Natl Acad Sci USA 96, 13777-13782.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13777-13782
-
-
Chehab, N.H.1
Malikzay, A.2
Stavridi, E.S.3
Halazonetis, T.D.4
-
283
-
-
0034723170
-
The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53
-
Li L, Ljungman M, and Dixon J (2000). The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. J Biol Chem, 275, 2410-2414.
-
(2000)
J Biol Chem
, vol.275
, pp. 2410-2414
-
-
Li, L.1
Ljungman, M.2
Dixon, J.3
-
284
-
-
0030016329
-
Apoptosis induction resulting from proteasome inhibition
-
Shinohara K, Tomioka M, Nakano H, Tone S, Ito H, and Kawashima S (1996). Apoptosis induction resulting from proteasome inhibition. Biochem J 317, 385-388.
-
(1996)
Biochem J
, vol.317
, pp. 385-388
-
-
Shinohara, K.1
Tomioka, M.2
Nakano, H.3
Tone, S.4
Ito, H.5
Kawashima, S.6
-
285
-
-
0031034160
-
Activation of the cell death program by inhibition of proteasome function
-
Drexler HCA (1997). Activation of the cell death program by inhibition of proteasome function. Proc Natl Acad Sci USA 94, 855-860.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 855-860
-
-
Drexler, H.C.A.1
-
286
-
-
0034142034
-
The human homologs of checkpoint kinases chk1 and cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh SY, Ahn J, Tamai K, Taya Y, and Prives C (2000). The human homologs of checkpoint kinases chk1 and cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 14, 289-300.
-
(2000)
Genes Dev
, vol.14
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
287
-
-
0034142325
-
Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
-
Chehab NH, Malikzay A, Appel M, and Halazonetis TD (2000). Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 14, 278-288.
-
(2000)
Genes Dev
, vol.14
, pp. 278-288
-
-
Chehab, N.H.1
Malikzay, A.2
Appel, M.3
Halazonetis, T.D.4
-
288
-
-
0034629072
-
DNA damage-induced activation of p53 by the checkpoint kinase chk2
-
Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, and Mak TW (2000). DNA damage-induced activation of p53 by the checkpoint kinase chk2. Science 287, 1824-1827.
-
(2000)
Science
, vol.287
, pp. 1824-1827
-
-
Hirao, A.1
Kong, Y.Y.2
Matsuoka, S.3
Wakeham, A.4
Ruland, J.5
Yoshida, H.6
Liu, D.7
Elledge, S.J.8
Mak, T.W.9
-
289
-
-
0033615647
-
Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53
-
Tominaga K, Morisaki H, Kaneko Y, Fujimoto A, Tanaka T, Ohtsubo M, Hirai M, Okayama H, Ikeda K, and Nakanishi M (1999). Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53. J Biol Chem 274, 31463-31467.
-
(1999)
J Biol Chem
, vol.274
, pp. 31463-31467
-
-
Tominaga, K.1
Morisaki, H.2
Kaneko, Y.3
Fujimoto, A.4
Tanaka, T.5
Ohtsubo, M.6
Hirai, M.7
Okayama, H.8
Ikeda, K.9
Nakanishi, M.10
-
290
-
-
0034624718
-
hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
-
Lee JS, Collins KM, Brown AL, Lee CH, and Chung JH (2000). hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 404, 201-204.
-
(2000)
Nature
, vol.404
, pp. 201-204
-
-
Lee, J.S.1
Collins, K.M.2
Brown, A.L.3
Lee, C.H.4
Chung, J.H.5
|