Translational regulation of human p53 gene expression

EMBO Journal

Volumn 15, Issue 16, 1996, Pages 4392-4401

  Fu, Loning ^a   Minden, Mark D ^a   Benchimol, Sam ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Acute myelogenous leukemia; p53; Translational control

Indexed keywords

MESSENGER RNA; PROTEIN P53;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BLAST CELL; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TRANSLATION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 0029766553     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00812.x     Document Type: Article

References (63)

1. Banks, L., Matlashewski, G. and Crawford, L. (1986) Isolation of human p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur. J. Biochem., 159, 529-534.
2. Benchimol, S., Munroe, D.G., Peacock, J., Gray, D. and Smith, L.J. (1989) Abnormalities in structure and expression of the p53 gene in leukemia. Cancer Cells, 7, 121-125.
3. Bienz, B., Zakut-Houri, R., Givol, D. and Oren, M. (1984) Analysis of the gene coding for the murine cellular tumour antisen p53. EMBO J., 3, 2179-2183.
4. Bienz-Tadmor, B., Zakut-Houri, R., Libresco, S., Givol, D. and Oren, M. (1985) The 5′ region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element. EMBO J., 4, 3209-3213.
5. Chirgwin, J.M., Przybyla, A.E., McDonald, R.J. and Rutter, W.J. (1979) Isolation of biochemically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18, 5294-5299.
6. Evans, T.C., Crittenden, S.L., Kodoyianni, V. and Kimble, J. (1994) Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryos. Cell, 77, 183-194.
7. Feinberg, A.P. and Vogelstein, B. (1983) A technique for radio-labeling DNA restriction endonuclease fragments to high specific activities. Anal. Biochem., 132, 6-13.
8. Fenaux, P., Jonveaux, P., Quiquandon, I., Laï, L., Pignon, J.M., Loucheux-Lefebvre, M.H., Bauters, F., Berger, R. and Kerckaert, J.P. (1991) p53 gene mutations in acute myeloid leukemia with 17p monosomy. Blood, 78, 1652-1657.
9. Fenaux, P., Preudhomme, C., Quiquandon, L., Jonveaux, P., Laï, J.L., Vanrumbeke, M., Loucheux-Lefebvre, M.H., Bauters, F., Berger, R. and Kerckaert, J.P. (1992) Mutations of the p53 gene in acute myeloid leukaemia. J. Haematol., 80, 178-183.
10. Feng, S. and Holland, F.C. (1988) HIV-1 tat trans-activation requires the loop sequence within tat. Nature, 334, 165-167.
11. Fialkow, P.J., Singer, J.W., Raskind, W.H., Adamson, J.W., Jacobson, R.J., Bernstein, I.D., Dow, L.W., Najfeld, V. and Veith, R. (1987) Clonal development, stem-cell differentiation, and clinical remission in acute nonlymphocytic leukemia. N. Engl. J. Med., 317, 468-473.
12. Fritsche, M., Haessler, C. and Brandner, G. (1993) Induction of nuclear accumulation of the tumor-suppressing protein p53 by DNA-damaging agents. Oncogene, 8, 307-318.
13. Fort, P., Marty, L., Piechaczyk, M., Sabrouty, S.E., Dani, C., Jeanteur, P. and Blanchard, J.M. (1985) Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res., 13, 1431-1442.
14. Fu, L., Ye, R., Browder, L.W. and Johnston, R.N. (1991) Translational potentiation of messenger RNA with secondary structure in Xenopus. Science, 251, 807-810.
15. Gavis, E.R. and Lehmann, R. (1994) Translational regulation of nanos by RNA localization. Nature, 369, 315-318.
16. Goodwin, E.B., Okkema, P.G., Evans, T.C. and Kimble, J. (1993) Translational regulation of tra-2 by its 3′ UTR controls sexual identity in C. elegans. Cell, 75, 329-339.
17. Harlow, E., Crawford, L.V., Pim, D.C. and Williamson, N.M. (1981) Monoclonal antibodies specific for Simian virus 40 tumor antigen. J. Virol., 39, 861-869.
18. Harlow, E., Williamson, N.M., Ralston, R., Helfman, D.M. and Adams, T.E. (1985) Molecular cloning and in vitro expression of a DNA clone for human cellular tumor antigen p53. Mol. Cell. Biol., 5, 1601-1610.
19. Herzog, H., Hofferer, L., Schneider, R. and Schweiger, M. (1990) cDNA encoding the human homologue of rat ribosomal protein L35a. Nucleic Acids Res., 18, 4600.
20. Hsu, H.C., Tseng, H.J., Lai, P.L., Lee, P.H. and Peng, S.Y. (1993) Expression of p53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness. Cancer Res., 53, 4691-4694.
21. Huarte, J., Stutz, A., O'Connell, M.L., Guber, P., Belin, D., Darrow, A.L., Strickland, S. and Vassalli, J.D. (1992) Transient translational silencing by reversible mRNA deadenylation. Cell, 69, 1021-1030.
22. Jackson, R.J. (1993) Cytoplasmic regulation of mRNA function: the importance of the 3′ UTR. Cell, 74, 9-14.
23. Kastan, M.B. et al. (1991a) Levels of p53 protein increase with maturation in human hematopoietic cells. Cancer Res., 51, 4279-4286.
24. Kastan, M.B., Onyekwere, O., Sidransky, D., Vogelstein, B. and Craig, R.W. (1991b) Participation of p53 protein in the cellular response to DNA damage. Cancer Res., 51, 6304-6311.
25. Kupiec, J.J., Giron, M.L., Viletter, D., Jeltsch, J.M. and Emanoil-Ravier, R. (1987) Isolation of high-molecular-weight DNA from eukaryotic cells by formamide treatment and dialysis. Anal. Biochem., 164, 53-59.
26. Kwon, Y.K. and Hecht, N.B. (1993) Binding of a phosphoprotein to the 3′ untranslated region of the mouse protamine 2 mRNA temporally represses its translation. Mol. Cell. Biol., 13, 6547-6557.
27. Lai, J.L., Preudhomme, C., Zandecki, M., Flactif, M., Vanrumbeke, M., Lepelley, P., Wattel, E. and Fenaux, P. (1995) Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of P53 mutations. Leukemia, 9, 370-381.
28. Lamb, P. and Crawford, L. (1986) Characterization of the human p53 gene. Mol. Cell. Biol., 6, 1379-1385.
29. Lu, X. and Lane, D.P. (1993) Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes? Cell, 75, 765-778.
30. Matlashewski, G., Lamb, P., Pim, D., Peacock, J., Crawford, L. and Benchimol, S. (1984) Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene. EMBO J., 13, 3257-3262.
31. Matlashewski, G., Banks, L., Pim, D. and Crawford, L.V. (1986) Analysis of human p53 proteins and mRNA levels in normal and transformed cells. Eur. J. Biochem., 154, 665-672.
32. Matlashewski, G.J., Tuck, S., Pim, D., Lamb, P., Schneider, J. and Crawford, L.V. (1987) Primary structure polymorphism at amino residue 72 of human p53. Mol. Cell. Biol., 7, 961-963.
33. Melefors, O. and Hentze, M.W. (1993) Translational regulation by mRNA-protein interactions in eukaryotic cells: ferritin and beyond. BioEssays, 15, 85-90.
34. Melton, D.A., Krieg, P., Rebagliati, M., Maniatis, T., Zinn, K. and Green, M. (1984) Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res., 12, 7035-7056.
35. Milner, J. (1991) A conformation hypothesis for the suppressor and promoter functions of p53 in cell growth control and in cancer. Proc. R. Soc. Lond. B., 245, 139-145.
36. Minden, M.D., Buick, R.N. and McCulloch, E.A. (1979) Separation of blast cell and T-lymphocyte progenitors in the blood of patients with acute myeloblastic leukemia. Blood, 54, 186-195.
37. Moll, U.M., Riou, G. and Levine, A.J. (1992) Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc. Natl Acad. Sci. USA, 89, 7262-7266.
38. Moll, U.M., LaQuaglia, M., Benard, J. and Riou, G. (1995) Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl Acad. Sci. USA, 92, 4407-4411.
39. Momand, J., Zambetti, G.P., Olson, D.C., George, D. and Levine, A.J. (1992) The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69, 1237-1245.
40. Mosner, J., Mummenbrauer, T., Bauer, C., Sczakiel, G., Grosse, F. and Deppert, W. (1995) Negative feedback regulation of wild-type p53 biosynthesis. EMBO J., 12, 4739-4746.
41. Oliner, J.D., Kinzler, K.W., Meltzer, P.S., George, D and Vogelstein, B. (1992) Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature, 358, 80-83.
42. Papayannopoulou, T., Nakomoto, B., Kurachi, S., Tweeddale, M. and Messner, H. (1988) Surface antigenic profile and globin phenotype of two new human erythroleukemia lines: characterization and interpretations. Blood, 72, 1029-1038.
43. Pause, A., Methot, N. and Sonenberg, N. (1993) The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis. Mol. Cell. Biol., 13, 6789-6798.
44. Rogel, A., Popliker, M., Webb, C.G. and Oren, M. (1985) p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors. Mol. Cell. Biol., 5, 2851-2855.
45. Sasano, H., Goukon, Y., Nishihia, T. and Nagura, H. (1992) In situ hybridization and immunohistochemistry of p53 tumor suppressor gene in human esophageal carcinoma. Am. J. Pathol., 141, 545-550.
46. Scheffner, M., Werness, B.A., Huibregtse, J.M., Levine, A.J. and Howley, P.M. (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63, 1129-1136.
47. Slingerland, J.M., Minden, M.D. and Benchimol, S. (1991) Mutations of the p53 gene in human acute myelogenous leukemia. Blood, 7, 1500-1507.
48. Smith, L.J., McCulloch, E.A. and Benchimol, S. (1986) Expression of the p53 oncogene in acute myeloblastic leukemia. J. Exp. Med., 164, 751-761.
49. Sugimoto, K., Toyoshima, H., Sakai, R., Miyagawa, K., Hagiwara, K., Hirai, H., Ishikana, F. and Takaku, F. (1991) Mutations of the p53 gene in lymphoid leukemia. Blood, 77, 1153-1156.
50. Sugimoto, K., Hirano, N., Toyoshima, H., Chiba, S., Mano, H., Takaku, F., Yazaki, Y. and Hirai, H. (1993) Mutations of the p53 gene in myelodysplastic syndromes and MDS-derived leukemia. Blood, 81, 3022-3026.
51. Torczynski, R.M., Fuke, M. and Bollon, A.P. (1985) Cloning and sequencing of a human 18S ribosomal RNA gene. DNA, 4, 283-291.
52. Trecca, D., Longo, L., Biondi, A., Cro, L., Calori, R., Grignani, F., Maiolo, A.T., Pelicci, P.G. and Neri, A. (1994) Analysis of p53 gene mutations in acute myeloid leukemia. Am. J. Hematol., 46, 304-309.
53. Tuck, S.P. and Crawford, L. (1989) Characterization of the human p53 gene promoter. Mol. Cell. Biol., 9, 2163-2172.
54. Ueda, H., Ullrich, S.J., Gangemi, J.D., Kappel, C.A., Ngo, L., Feitelson, M.A. and Jay, G. (1995) Functional inactivation but not structural mutation of p53 causes liver cancer. Nature Genet., 9, 41-47.
55. Ullrich, S.J., Mercer, W.E. and Appella, E. (1992) Human wild-type p53 adopts a unique conformational and phosphorylation state in vivo during growth arrest of glioblastoma cells. Oncogene, 7, 1635-1643.
56. Wang, C., Curtis, J.E., Minden, M.D. and McCulloch, E.A. (1989) Expression of a retinoic acid receptor gene in myeloid leukemia cells. Leukemia, 3, 264-269.
57. Wattel, E., Preudhomme, C., Hecquet, B., Vanrumbeke, M., Quesnel, B., Dervite, I., Morel, P. and Fenaux, P. (1994) p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood, 84, 3148-3157.
58. Wiggans, R.G., Jacobson, R.J., Fialkow, P.J., Woolley, P.V., Macdonald, S.J. and Schein, P.S. (1978) Probable clonal origin of acute myeloblastic leukemia following radiation and chemotherapy of colon cancer. Blood, 52, 650-663.
59. Winship, P.R. (1989) An improved method for directly sequencing PCR amplified material using dimethyl sulphoxide. Nucleic Acids Res., 17, 1266.
60. Winter, E., Yamamoto, F., Almoguera, C. and Perucho, M. (1985) A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant C-Ki-ras allele in human tumor cells. Proc. Natl Acad. Sci. USA, 82, 7575-7579.
61. Zhan, Q., Carrier, F and Fornace, A.J., Jr (1993) Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol., 13, 4242-4250.
62. Zhang, W., Hu, G., Estey, E., Hester, J. and Deisseroth, A. (1992) Altered conformation of the p53 protein in myeloid leukemia cells and mitogen-stimulated normal blood cells. Oncogene, 7, 1645-1647.
63. Zhu, Y.M., Bradbury, D. and Russell, N. (1993) Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristics. Br. J. Cancer, 68, 851-855.