메뉴 건너뛰기




Volumn 58, Issue 8, 1998, Pages 1723-1729

Antioxidant action via p53-mediated apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; DNA; PROPRANOLOL DERIVATIVE; PROTEIN P53; TROLOX C;

EID: 0032522798     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (118)

References (65)
  • 4
    • 0028939139 scopus 로고
    • Programmed cell death and Bcl-2 protection in very low oxygen
    • Jacobson, M. D., and Raff, M. C. Programmed cell death and Bcl-2 protection in very low oxygen. Nature (Lond.), 374: 814-816, 1995.
    • (1995) Nature (Lond.) , vol.374 , pp. 814-816
    • Jacobson, M.D.1    Raff, M.C.2
  • 6
    • 0021964203 scopus 로고
    • Prooxidant States and tumor promotion
    • Washington DC
    • Cerutti, P. A. Prooxidant States and tumor promotion. Science (Washington DC), 227: 375-381, 1985.
    • (1985) Science , vol.227 , pp. 375-381
    • Cerutti, P.A.1
  • 7
    • 0025228499 scopus 로고
    • Inhibition of transformation in cultured rat tracheal epithelial cells by potential chemopreventive agents
    • Steele, V. E., Kelloff, G. J., Wilkinson, B. P., and Arnold, J. T. Inhibition of transformation in cultured rat tracheal epithelial cells by potential chemopreventive agents. Cancer Res., 50: 2068-2074, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2068-2074
    • Steele, V.E.1    Kelloff, G.J.2    Wilkinson, B.P.3    Arnold, J.T.4
  • 8
    • 0028610423 scopus 로고
    • Antioxidants and cancer: Molecular mechanisms
    • D. Armstrong (ed.), New York: Plenum Press
    • O'Brien, P. Antioxidants and cancer: molecular mechanisms. In: D. Armstrong (ed.), Free Radicals in Diagnostic Medicine, pp. 215-239. New York: Plenum Press, 1994.
    • (1994) Free Radicals in Diagnostic Medicine , pp. 215-239
    • O'Brien, P.1
  • 9
    • 0022472405 scopus 로고
    • Inhibition of urethane-induced lung tumors in mice by dietary N-acetylcysteine
    • Flora, S. D., Astengo, M., Serra, D., and Bennicelli, C. Inhibition of urethane-induced lung tumors in mice by dietary N-acetylcysteine. Cancer Lett., 32: 235-241, 1986.
    • (1986) Cancer Lett. , vol.32 , pp. 235-241
    • Flora, S.D.1    Astengo, M.2    Serra, D.3    Bennicelli, C.4
  • 10
    • 0023757233 scopus 로고
    • Anticarcinogenesis mechanisms, as evaluated in the multistage mouse skin model
    • Rostein, J. B., and Slaga, T. J. Anticarcinogenesis mechanisms, as evaluated in the multistage mouse skin model. Mutat. Res., 202: 421-427, 1988.
    • (1988) Mutat. Res. , vol.202 , pp. 421-427
    • Rostein, J.B.1    Slaga, T.J.2
  • 11
    • 0026349661 scopus 로고
    • Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon
    • Pereira, M. A., and Khoury, M. D. Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon. Cancer Lett., 61: 27-33, 1991.
    • (1991) Cancer Lett. , vol.61 , pp. 27-33
    • Pereira, M.A.1    Khoury, M.D.2
  • 12
    • 0000067911 scopus 로고
    • Chemopreventive properties of N-acetylcysteine and other thiols
    • L. Wattenberg, M. Lipkin, C. W. Boone, and G. J. Kelloff (eds.), Boca Raton, FL: CRC Press
    • Flora, S. D., Izzotti, A., D'Agostino, F., Balansky, R., and Cesarone, C. F. Chemopreventive properties of N-acetylcysteine and other thiols. In: L. Wattenberg, M. Lipkin, C. W. Boone, and G. J. Kelloff (eds.), Cancer Chemoprevention, pp. 183-194. Boca Raton, FL: CRC Press, 1992.
    • (1992) Cancer Chemoprevention , pp. 183-194
    • Flora, S.D.1    Izzotti, A.2    D'Agostino, F.3    Balansky, R.4    Cesarone, C.F.5
  • 14
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko, L. J., and Prives, C. p53: puzzle and paradigm. Genes Dev., 10: 1054-1072, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 15
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 16
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara, T., Grimm, E. A., Mukhopadhyay, T., Zhang, W., Owen-Schaub, L. B., and Roth, J. A. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res., 54: 2287-2291, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Zhang, W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 17
    • 0029017333 scopus 로고
    • Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
    • Liu, T. J., El-Naggar, A. K., McDonnell, T. J., Steck, K. D., Wang, M., Taylor, D. L., and Clayman, G. L. Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck. Cancer Res., 55: 3117-3122, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3117-3122
    • Liu, T.J.1    El-Naggar, A.K.2    McDonnell, T.J.3    Steck, K.D.4    Wang, M.5    Taylor, D.L.6    Clayman, G.L.7
  • 18
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 20
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend, S.11    Fornace, A.J.12    Kohn, K.W.13
  • 21
    • 0027361046 scopus 로고
    • Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
    • Hainaut, P., and Milner, J. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res., 53: 4469-4473, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4469-4473
    • Hainaut, P.1    Milner, J.2
  • 22
    • 0027250493 scopus 로고
    • Activation of the cryptic DNA binding function of mutant forms of p53
    • Hupp, T. R., Meek, D. W., Midgley, C. A., and Lane, D. P. Activation of the cryptic DNA binding function of mutant forms of p53. Nucleic Acids Res., 21: 3167-3174, 1993.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 3167-3174
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4
  • 25
    • 0029060986 scopus 로고
    • UV-B/A irradiation of mouse keratinocytes results in p53-mediated WAF1/CIP1 expression
    • Liu, M., and Pelling, J. C. UV-B/A irradiation of mouse keratinocytes results in p53-mediated WAF1/CIP1 expression. Oncogene, 10: 1955-1960, 1995.
    • (1995) Oncogene , vol.10 , pp. 1955-1960
    • Liu, M.1    Pelling, J.C.2
  • 26
    • 0026303190 scopus 로고
    • p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
    • Harney, D. M., and Levine, A. J. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev., 5: 2375-2385, 1991.
    • (1991) Genes Dev. , vol.5 , pp. 2375-2385
    • Harney, D.M.1    Levine, A.J.2
  • 31
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S. D., Williams, B. O., Jacks, T., and DePinho, R. A. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature (Lond.), 371: 72-74, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 32
    • 0029875821 scopus 로고    scopus 로고
    • Cellular proofreading
    • Brash, D. E. Cellular proofreading. Nat. Med., 2: 525-526, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 525-526
    • Brash, D.E.1
  • 34
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
    • Fritsche, M., Haessler, C., and Brandner, G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene, 8: 307-318, 1993.
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 35
    • 0028233868 scopus 로고
    • Increase in p53 protein half-life in mouse keratinocytes following UV-B irradiation
    • Lond.
    • Liu, M., Dhanwada, K. R., Birt, D. F., Hecht, S., and Pelling, J. C. Increase in p53 protein half-life in mouse keratinocytes following UV-B irradiation. Carcinogenesis (Lond.), 15: 1089-1092, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1089-1092
    • Liu, M.1    Dhanwada, K.R.2    Birt, D.F.3    Hecht, S.4    Pelling, J.C.5
  • 36
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
    • Maltzman, W., and Czyzyk, L. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol. Cell. Biol., 4: 1689-1694, 1984.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 37
    • 0027501966 scopus 로고
    • Increased sequence-specific p53-DNA binding activity after DNA damage is attenuated by phorbol ester
    • Price, B. D., and Calderwood, S. K. Increased sequence-specific p53-DNA binding activity after DNA damage is attenuated by phorbol ester. Oncogene, 8: 3055-3062, 1993.
    • (1993) Oncogene , vol.8 , pp. 3055-3062
    • Price, B.D.1    Calderwood, S.K.2
  • 38
    • 0022994861 scopus 로고
    • DNA damage induced by chloramphenicol and nitroso-chloramphenicol: Protection by N-acetylcysteine
    • Yunis, A. A., Lim, L. O., and Arimura, G. K. DNA damage induced by chloramphenicol and nitroso-chloramphenicol: protection by N-acetylcysteine. Respiration, 50 (Suppl.): 50-55, 1986.
    • (1986) Respiration , vol.50 , Issue.SUPPL. , pp. 50-55
    • Yunis, A.A.1    Lim, L.O.2    Arimura, G.K.3
  • 39
    • 0022796505 scopus 로고
    • Protective role of thiols in carcinogen-induced DNA damage in rat liver
    • Lond.
    • Chan, J. Y. H., Stout, D. L., and Becker, F. F. Protective role of thiols in carcinogen-induced DNA damage in rat liver. Carcinogenesis (Lond.), 7: 1621-1624, 1986.
    • (1986) Carcinogenesis , vol.7 , pp. 1621-1624
    • Chan, J.Y.H.1    Stout, D.L.2    Becker, F.F.3
  • 40
    • 0027420308 scopus 로고
    • Radioprotective effect of N-acetylcysteine in vitro using the induction of DNA breaks as end-point
    • Solen, G. Radioprotective effect of N-acetylcysteine in vitro using the induction of DNA breaks as end-point. Int. J. Radiat. Biol., 64: 359-366, 1993.
    • (1993) Int. J. Radiat. Biol. , vol.64 , pp. 359-366
    • Solen, G.1
  • 41
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid
    • Aruoma, O. I., Halliwell, B., Hoey, B. M., and Butler, J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid. Free Radic. Biol. Med., 6: 593-597, 1989.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 42
    • 0023081006 scopus 로고
    • Intracellular delivery of cysteine
    • Anderson, M. E., and Meister, A. Intracellular delivery of cysteine. Methods Enzymol., 143: 313-325, 1987.
    • (1987) Methods Enzymol. , vol.143 , pp. 313-325
    • Anderson, M.E.1    Meister, A.2
  • 43
    • 0025030336 scopus 로고
    • Antioxidant protection against damage during cardiac ischemia and reperfusion: Effect of dimercaptopropanol
    • Ceconi, C., Curello, S., Cargnoni, A., Boffa, G. M., and Ferrari, R. Antioxidant protection against damage during cardiac ischemia and reperfusion: effect of dimercaptopropanol. Cardioscience, 1: 191-198, 1990.
    • (1990) Cardioscience , vol.1 , pp. 191-198
    • Ceconi, C.1    Curello, S.2    Cargnoni, A.3    Boffa, G.M.4    Ferrari, R.5
  • 45
    • 0024512008 scopus 로고
    • Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration
    • Burgunder, J. M., Varriale, A., and Lauterburg, B. H. Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur. J. Clin. Pharmacol., 36: 127-131, 1989.
    • (1989) Eur. J. Clin. Pharmacol. , vol.36 , pp. 127-131
    • Burgunder, J.M.1    Varriale, A.2    Lauterburg, B.H.3
  • 47
    • 0029834677 scopus 로고    scopus 로고
    • Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines
    • Lotem, J., Peled-Kamar, M., Groner, Y., and Sachs, L. Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines. Proc. Natl. Acad. Sci. USA, 93: 9166-9171, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9166-9171
    • Lotem, J.1    Peled-Kamar, M.2    Groner, Y.3    Sachs, L.4
  • 49
    • 0029968126 scopus 로고    scopus 로고
    • Role of Fenton chemistry in thiol-induced toxicity and apoptosis
    • Held, K. D., Sylvester, C. S., Hopcia, K. L., and Biaglow, J. E. Role of Fenton chemistry in thiol-induced toxicity and apoptosis. Radiat. Res., 145: 542-553, 1996.
    • (1996) Radiat. Res. , vol.145 , pp. 542-553
    • Held, K.D.1    Sylvester, C.S.2    Hopcia, K.L.3    Biaglow, J.E.4
  • 50
    • 0028204160 scopus 로고
    • DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
    • Nelson, W. G., and Kastan, M. B. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol., 14: 1815-1823, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1815-1823
    • Nelson, W.G.1    Kastan, M.B.2
  • 51
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defect in chromosome instability syndrome?
    • Lu, X., and Lane, D. P. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defect in chromosome instability syndrome? Cell, 75; 765-778, 1993.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 52
    • 0027486024 scopus 로고
    • Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells
    • Khanna, K. K., and Lavin, M. F. Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. Oncogene, 8: 3307-3312, 1993.
    • (1993) Oncogene , vol.8 , pp. 3307-3312
    • Khanna, K.K.1    Lavin, M.F.2
  • 53
    • 0020123456 scopus 로고
    • Determination of DNA superhelicity and extremely low levels of DNA strand breaks in low numbers of nonradiolabeled cells by DNA-4′,6-diamidino-2-phenylindole fluorescence in nucleoid gradients
    • Lipetz, P. D., Brash, D. E., Joseph, L. B., Jewett, H. D., Lisle, D. R., Lantry, L. E., Hart, R. W., and Stephens, R. E. Determination of DNA superhelicity and extremely low levels of DNA strand breaks in low numbers of nonradiolabeled cells by DNA-4′,6-diamidino-2-phenylindole fluorescence in nucleoid gradients. Anal. Biochem., 121: 339-348, 1982.
    • (1982) Anal. Biochem. , vol.121 , pp. 339-348
    • Lipetz, P.D.1    Brash, D.E.2    Joseph, L.B.3    Jewett, H.D.4    Lisle, D.R.5    Lantry, L.E.6    Hart, R.W.7    Stephens, R.E.8
  • 55
    • 0029948586 scopus 로고    scopus 로고
    • Oxidative stress is involved in the UV activation of p53
    • Renzing, J., Hansen, S., and Lane, D. P. Oxidative stress is involved in the UV activation of p53. J. Cell Sci., 109: 1105-1112, 1996.
    • (1996) J. Cell Sci. , vol.109 , pp. 1105-1112
    • Renzing, J.1    Hansen, S.2    Lane, D.P.3
  • 57
    • 0029766553 scopus 로고    scopus 로고
    • Translational regulation of human p53 gene expression
    • Fu, L., Minden, M. D., and Benchimol, S. Translational regulation of human p53 gene expression. EMBO J., 15: 4392-4401, 1996.
    • (1996) EMBO J. , vol.15 , pp. 4392-4401
    • Fu, L.1    Minden, M.D.2    Benchimol, S.3
  • 58
    • 0030111238 scopus 로고    scopus 로고
    • The role of thymidylate synthase as an RNA-binding protein
    • Chu, E., and Allegra, C. J. The role of thymidylate synthase as an RNA-binding protein. Bioessays, 18: 191-198, 1996.
    • (1996) Bioessays , vol.18 , pp. 191-198
    • Chu, E.1    Allegra, C.J.2
  • 60
    • 0029760957 scopus 로고    scopus 로고
    • Redox regulation of transcriptional activators
    • Sun, Y., and Oberley, L. W. Redox regulation of transcriptional activators. Free Radic. Biol. Med., 21: 335-348, 1996.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 335-348
    • Sun, Y.1    Oberley, L.W.2
  • 61
    • 0025959339 scopus 로고
    • Clinical pharmacokinetics of N-acetylcysteine
    • Holdiness, M. R. Clinical pharmacokinetics of N-acetylcysteine. Clin. Pharmacokinet., 20: 123-134, 1991.
    • (1991) Clin. Pharmacokinet. , vol.20 , pp. 123-134
    • Holdiness, M.R.1
  • 62
    • 0004293286 scopus 로고    scopus 로고
    • Montvale, NJ: Medical Economics Data
    • Weiner, B. (ed.) PDR Generics, 2nd ed. Montvale, NJ: Medical Economics Data, 1996.
    • (1996) PDR Generics, 2nd Ed.
    • Weiner, B.1
  • 64
    • 0030683947 scopus 로고    scopus 로고
    • To oxidize or not to oxidize?
    • Kastan, M. B. To oxidize or not to oxidize? Nat. Med., 3: 1192-1193, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 1192-1193
    • Kastan, M.B.1
  • 65
    • 0031444312 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
    • Ahmad, N., Feyes, D. K., Nieminen, A., Agarwal, R., and Mukhtar, H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J. Natl. Cancer Inst., 89: 1881-1886, 1997.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1881-1886
    • Ahmad, N.1    Feyes, D.K.2    Nieminen, A.3    Agarwal, R.4    Mukhtar, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.