메뉴 건너뛰기




Volumn 57, Issue 22, 1997, Pages 5168-5178

The role of CDc2 feedback loop control in the DNA damage checkpoint in mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; NOCODAZOLE; PACLITAXEL; PHOSPHATASE; PROTEIN KINASE; PROTEIN P21; PROTEIN P53;

EID: 0030665150     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (132)

References (108)
  • 1
  • 2
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D. O. Principles of CDK regulation. Nature (Lond.), 374: 131-134, 1995.
    • (1995) Nature (Lond.) , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 3
    • 0029767016 scopus 로고    scopus 로고
    • Structural basis of cyclin-dependent kinase activation by phosphorylation
    • Russo, A. A., Jeffrey, P. D., and Pavletich, N. P. Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat. Struct. Biol., 3: 696-700, 1996.
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 696-700
    • Russo, A.A.1    Jeffrey, P.D.2    Pavletich, N.P.3
  • 4
    • 0031026679 scopus 로고    scopus 로고
    • Cell cycle: Will the real Cdk-activating kinase please stand up
    • Draetta, G. F. Cell cycle: will the real Cdk-activating kinase please stand up. Curr. Biol., 7: 50-52, 1997.
    • (1997) Curr. Biol. , vol.7 , pp. 50-52
    • Draetta, G.F.1
  • 5
    • 0028970682 scopus 로고
    • 160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin
    • Washington DC
    • 160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin. Science (Washington DC), 270: 90-93, 1995.
    • (1995) Science , vol.270 , pp. 90-93
    • Poon, R.Y.C.1    Hunter, T.2
  • 6
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr, C. J., and Roberts, J. M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev., 9: 1149-1163, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 7
    • 15144339105 scopus 로고
    • Mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2
    • Lundgren, K., Walworth, N., Booher, R., Debski, M., Kirschner, M., and Beach, D. mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell, 58: 193-203, 1991.
    • (1991) Cell , vol.58 , pp. 193-203
    • Lundgren, K.1    Walworth, N.2    Booher, R.3    Debski, M.4    Kirschner, M.5    Beach, D.6
  • 8
    • 0026616796 scopus 로고
    • cdc2-cyclin B complex by the human WEE1 tyrosine kinase
    • Washington DC
    • cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science (Washington DC), 257: 1955-1957, 1992.
    • (1992) Science , vol.257 , pp. 1955-1957
    • Parker, L.L.1    Piwnica-Worms, H.2
  • 9
    • 0029048491 scopus 로고
    • Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle
    • Watanabe, N., Broome, M., and Hunter, T. Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. EMBO J., 14: 1878-1891, 1995.
    • (1995) EMBO J. , vol.14 , pp. 1878-1891
    • Watanabe, N.1    Broome, M.2    Hunter, T.3
  • 11
    • 0029000155 scopus 로고
    • Cell cycle regulation of human WEE1
    • McGowan, C. H., and Russell, P. Cell cycle regulation of human WEE1. EMBO J., 14: 2166-2175, 1995.
    • (1995) EMBO J. , vol.14 , pp. 2166-2175
    • McGowan, C.H.1    Russell, P.2
  • 12
    • 0027201553 scopus 로고
    • Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase
    • Wu, L., and Russell, P. Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase. Nature (Lond.), 363: 738-741, 1993.
    • (1993) Nature (Lond.) , vol.363 , pp. 738-741
    • Wu, L.1    Russell, P.2
  • 13
    • 0027267674 scopus 로고
    • Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase
    • Parker, L. L., Walter, S. A., Young, P., and Piwnica-Worms, H. Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature (Lond.), 363: 736-738, 1993.
    • (1993) Nature (Lond.) , vol.363 , pp. 736-738
    • Parker, L.L.1    Walter, S.A.2    Young, P.3    Piwnica-Worms, H.4
  • 14
    • 0027514175 scopus 로고
    • Negative regulation of the Wee1 protein kinase by direct action of the nim1/cdr1 mitotic inducer
    • Coleman, T. R., Tang, Z., and Dunphy, W.G. Negative regulation of the Wee1 protein kinase by direct action of the nim1/cdr1 mitotic inducer. Cell, 72: 919-929, 1993.
    • (1993) Cell , vol.72 , pp. 919-929
    • Coleman, T.R.1    Tang, Z.2    Dunphy, W.G.3
  • 15
    • 0027208148 scopus 로고
    • Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
    • Walworth, N., Davey, S., and Beach, D. Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature (Lond.), 363: 368-371, 1993.
    • (1993) Nature (Lond.) , vol.363 , pp. 368-371
    • Walworth, N.1    Davey, S.2    Beach, D.3
  • 16
    • 0031035528 scopus 로고    scopus 로고
    • Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
    • O'Connell, M. J., Raleigh, J. M., Verkade, H. M., and Nurse, P. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J., 16: 545-554, 1997.
    • (1997) EMBO J. , vol.16 , pp. 545-554
    • O'Connell, M.J.1    Raleigh, J.M.2    Verkade, H.M.3    Nurse, P.4
  • 17
    • 0027236688 scopus 로고
    • Two distinct mechanisms for negative regulation of the Wee1 protein kinase
    • Tang, Z., Coleman, T. R., and Dunphy, W. G. Two distinct mechanisms for negative regulation of the Wee1 protein kinase. EMBO J., 12: 3427-3436, 1993.
    • (1993) EMBO J. , vol.12 , pp. 3427-3436
    • Tang, Z.1    Coleman, T.R.2    Dunphy, W.G.3
  • 20
    • 0028783413 scopus 로고
    • Myt1: A membrane-associated inhibitory kinase that phosphorylates CDC2 on both threonine-14 and tyrosine-15
    • Washington DC
    • Mueller, P. R., Coleman, T. R., Kumagai, A., and Dunphy, W. G. Myt1: a membrane-associated inhibitory kinase that phosphorylates CDC2 on both threonine-14 and tyrosine-15. Science (Washington DC), 270: 86-90, 1995.
    • (1995) Science , vol.270 , pp. 86-90
    • Mueller, P.R.1    Coleman, T.R.2    Kumagai, A.3    Dunphy, W.G.4
  • 21
    • 0029880475 scopus 로고    scopus 로고
    • Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine brain
    • Matsuura, I., and Wang, J. H. Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine brain. J. Biol. Chem., 271: 5443-5450, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5443-5450
    • Matsuura, I.1    Wang, J.H.2
  • 22
    • 0025980359 scopus 로고
    • The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system
    • Kumagai, A., and Dunphy, W. G. The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system. Cell, 64: 903-914, 1991.
    • (1991) Cell , vol.64 , pp. 903-914
    • Kumagai, A.1    Dunphy, W.G.2
  • 25
    • 0026234297 scopus 로고
    • An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
    • Nagata, A., Igarashi, M., Jinno, S., Suto, K., and Okayama, H. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol., 3: 959-968, 1991.
    • (1991) New Biol. , vol.3 , pp. 959-968
    • Nagata, A.1    Igarashi, M.2    Jinno, S.3    Suto, K.4    Okayama, H.5
  • 26
    • 0025324692 scopus 로고
    • Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
    • Sadhu, K., Reed, S. I., Richardson, H., and Russell, P. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. USA, 87: 5139-5143, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5139-5143
    • Sadhu, K.1    Reed, S.I.2    Richardson, H.3    Russell, P.4
  • 27
    • 0026319225 scopus 로고
    • Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
    • Galaktionov, K., and Beach, D. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell, 67: 1181-1194, 1991.
    • (1991) Cell , vol.67 , pp. 1181-1194
    • Galaktionov, K.1    Beach, D.2
  • 30
    • 0027509501 scopus 로고
    • Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
    • Huffman, I., Clarke, P. R., Marcote, M. J., Karsenti, E., and Draetta, G. Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J., 12: 53-63, 1993.
    • (1993) EMBO J. , vol.12 , pp. 53-63
    • Huffman, I.1    Clarke, P.R.2    Marcote, M.J.3    Karsenti, E.4    Draetta, G.5
  • 31
    • 0027746003 scopus 로고
    • Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase
    • Izumi, T., and Maller, J. L. Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase. Mol. Biol. Cell, 4: 1337-1350, 1993.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1337-1350
    • Izumi, T.1    Maller, J.L.2
  • 32
    • 0029039470 scopus 로고
    • Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity
    • Izumi, T., and Maller, J. L. Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity. Mol. Biol. Cell, 6: 215-226, 1995.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 215-226
    • Izumi, T.1    Maller, J.L.2
  • 33
    • 0029821131 scopus 로고    scopus 로고
    • Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts
    • Washington DC
    • Kumagai, A., and Dunphy, W. G. Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts. Science (Washington DC), 273: 1377-1380, 1996.
    • (1996) Science , vol.273 , pp. 1377-1380
    • Kumagai, A.1    Dunphy, W.G.2
  • 34
    • 0028149892 scopus 로고
    • Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216
    • Ogg, S., Gabrielli, B., and Piwnica-Worms, H. Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216. J. Biol. Chem., 269: 30461-30469, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30461-30469
    • Ogg, S.1    Gabrielli, B.2    Piwnica-Worms, H.3
  • 35
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Washington DC
    • Hartwell, L. H., and Weinert, T. A. Checkpoints: controls that ensure the order of cell cycle events. Science (Washington DC), 246: 629-634, 1989.
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 36
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Washington DC
    • Elledge, S. J. Cell cycle checkpoints: preventing an identity crisis. Science (Washington DC), 274: 1664-1671, 1996.
    • (1996) Science , vol.274 , pp. 1664-1671
    • Elledge, S.J.1
  • 37
    • 0029807526 scopus 로고    scopus 로고
    • Viewpoint: Putting the cell cycle in order
    • Washington DC
    • Nasmyth, K. Viewpoint: putting the cell cycle in order. Science (Washington DC), 274: 1643-1645, 1996.
    • (1996) Science , vol.274 , pp. 1643-1645
    • Nasmyth, K.1
  • 38
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • Di Leonardo, A., Linke, S. P., Clarkin, K., and Wahl, G. M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev., 8: 2540-2551, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2540-2551
    • Di Leonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 39
    • 0029097316 scopus 로고
    • Molecular controls of growth arrest and apoptosis: P53-dependent and independent pathways
    • Liebermann, D. A., Hoffman, B., and Steinman, R. A. Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways. Oncogene, 11: 199-210, 1995.
    • (1995) Oncogene , vol.11 , pp. 199-210
    • Liebermann, D.A.1    Hoffman, B.2    Steinman, R.A.3
  • 41
    • 0028092030 scopus 로고
    • Induction of apoptosis by the anti-tubulin drug colcemid: Relationship of mitotic checkpoint control to the induction of apoptosis in HeLa S3 cells
    • Sherwood, S. W., Sheridan, J. P., and Schimke, R. T. Induction of apoptosis by the anti-tubulin drug colcemid: relationship of mitotic checkpoint control to the induction of apoptosis in HeLa S3 cells. Exp. Cell Res., 215: 373-379, 1994.
    • (1994) Exp. Cell Res. , vol.215 , pp. 373-379
    • Sherwood, S.W.1    Sheridan, J.P.2    Schimke, R.T.3
  • 43
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levin, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levin, A.J.1
  • 44
    • 0028978183 scopus 로고
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell, 82: 675-684, 1995.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 46
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman, T., Kinzler, K. W., and Vogelstein, B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res., 55: 5187-5190, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 48
    • 0029934461 scopus 로고    scopus 로고
    • Cyclin-dependent kinases are inactivated by a combination of p21 and Thr14/Tyr15 phosphorylation after UV-induced DNA damage
    • Poon, R. Y. C., Jiang, W., Toyoshima, H., and Hunter, T. Cyclin-dependent kinases are inactivated by a combination of p21 and Thr14/Tyr15 phosphorylation after UV-induced DNA damage. J. Biol. Chem., 271: 13283-13291, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13283-13291
    • Poon, R.Y.C.1    Jiang, W.2    Toyoshima, H.3    Hunter, T.4
  • 50
    • 0017887963 scopus 로고
    • Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens
    • Kakunaga, T. Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens. Proc. Natl. Acad. Sci. USA, 75: 1334-1338, 1978.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 1334-1338
    • Kakunaga, T.1
  • 51
    • 0029145975 scopus 로고
    • Redistribution of the CDK inhibitor p27 between different cyclin-CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or UV irradiation
    • Poon, R. Y. C., Toyoshima, H., and Hunter, T. Redistribution of the CDK inhibitor p27 between different cyclin-CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or UV irradiation. Mol. Biol. Cell, 6: 1197-1213, 1995.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1197-1213
    • Poon, R.Y.C.1    Toyoshima, H.2    Hunter, T.3
  • 52
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
    • Lu, X., and Lane, D. P. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell, 75: 765-778, 1993.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 55
    • 0028354340 scopus 로고
    • Reversible immunoprecipitation using histidine-or glutathione-S-transferase-tagged staphylococcal protein A
    • Poon, R. Y. C., and Hunt, T. Reversible immunoprecipitation using histidine-or glutathione-S-transferase-tagged staphylococcal protein A. Anal. Biochem., 218: 26-33, 1994.
    • (1994) Anal. Biochem. , vol.218 , pp. 26-33
    • Poon, R.Y.C.1    Hunt, T.2
  • 58
    • 0025090934 scopus 로고
    • Human cyclin A is adenovirus E1A-associated protein p60, and behaves differently from cyclin B
    • Pines, J., and Hunter, T. Human cyclin A is adenovirus E1A-associated protein p60, and behaves differently from cyclin B. Nature (Lond.), 346: 760-763, 1990.
    • (1990) Nature (Lond.) , vol.346 , pp. 760-763
    • Pines, J.1    Hunter, T.2
  • 60
    • 0029940855 scopus 로고    scopus 로고
    • Role of cyclin A and p27 in anti-IgM-induced G1 growth arrest of murine B-cell lymphomas
    • Ezhevsky, S. A., Toyoshima, H., Hunter, T., and Scott, D. W. Role of cyclin A and p27 in anti-IgM-induced G1 growth arrest of murine B-cell lymphomas. Mol. Biol. Cell. 7: 553-564, 1996.
    • (1996) Mol. Biol. Cell. , vol.7 , pp. 553-564
    • Ezhevsky, S.A.1    Toyoshima, H.2    Hunter, T.3    Scott, D.W.4
  • 61
    • 0026506719 scopus 로고
    • Cyclin A-dependent and cyclin B-dependent protein-kinases are regulated by different mechanisms in Xenopus egg extracts
    • Clarke, P. R., Leiss, D., Pagano, M., and Karsenti, E. Cyclin A-dependent and cyclin B-dependent protein-kinases are regulated by different mechanisms in Xenopus egg extracts. EMBO J., 11: 1751-1761, 1992.
    • (1992) EMBO J. , vol.11 , pp. 1751-1761
    • Clarke, P.R.1    Leiss, D.2    Pagano, M.3    Karsenti, E.4
  • 62
    • 0000297058 scopus 로고
    • Taxol stabilizes microtubules in mouse fibroblast cells
    • Schiff, P. B., and Horwitz, S. B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA, 77: 1561-1565, 1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 1561-1565
    • Schiff, P.B.1    Horwitz, S.B.2
  • 63
    • 0028135173 scopus 로고
    • Cdc2 regulatory factors
    • Coleman, T. R., and Dunphy, W. G. Cdc2 regulatory factors. Curr. Biol., 6: 877-882, 1994.
    • (1994) Curr. Biol. , vol.6 , pp. 877-882
    • Coleman, T.R.1    Dunphy, W.G.2
  • 64
    • 0027990255 scopus 로고
    • A cyclin-dependent kinase inhibitor, butyrolactone , I, inhibits phosphorylation of RB protein and cell cycle progression
    • Kitagawa, M., Higashi, H., Takahashi, I. S., Okabe, T., Ogino, H., Taya, Y., Hishimura, S., and Okuyama, A. A cyclin-dependent kinase inhibitor, butyrolactone , I, inhibits phosphorylation of RB protein and cell cycle progression. Oncogene, 9: 2549-2557, 1994.
    • (1994) Oncogene , vol.9 , pp. 2549-2557
    • Kitagawa, M.1    Higashi, H.2    Takahashi, I.S.3    Okabe, T.4    Ogino, H.5    Taya, Y.6    Hishimura, S.7    Okuyama, A.8
  • 65
    • 0022517046 scopus 로고
    • Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells
    • Washington DC
    • Schlegel, R., and Pardee, A. B. Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells. Science (Washington DC), 232: 1264-1266, 1986.
    • (1986) Science , vol.232 , pp. 1264-1266
    • Schlegel, R.1    Pardee, A.B.2
  • 66
    • 0023730252 scopus 로고
    • Caffeine induces uncoordinated expression of cell cycle functions after ultraviolet irradiation. Accelerated cycle transit, sister chromatid exchanges and premature chromosome condensation in a transformed Indian muntjac cell line
    • Musk, S. R., Downes, C. S., and Johnson, R. T. Caffeine induces uncoordinated expression of cell cycle functions after ultraviolet irradiation. Accelerated cycle transit, sister chromatid exchanges and premature chromosome condensation in a transformed Indian muntjac cell line. J. Cell Sci., 90: 591-599, 1988.
    • (1988) J. Cell Sci. , vol.90 , pp. 591-599
    • Musk, S.R.1    Downes, C.S.2    Johnson, R.T.3
  • 68
    • 0027466647 scopus 로고
    • Caffeine release of radiation induced S and G2 phase arrest in V79 hamster cells: Increase of histone messenger RNA levels and p34cdc2 activation
    • Hain, J., Crompton, N. E., Burkart, W., and Jaussi, R. Caffeine release of radiation induced S and G2 phase arrest in V79 hamster cells: increase of histone messenger RNA levels and p34cdc2 activation. Cancer Res., 53: 1507-1510, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1507-1510
    • Hain, J.1    Crompton, N.E.2    Burkart, W.3    Jaussi, R.4
  • 72
    • 0029001624 scopus 로고
    • p53 involvement in control of G2 exit of the cell cycle: Role in DNA damage-induced apoptosis
    • Guillouf, C., Rosselli, F., Krishnaraju, K., Moustacchi, E., Hoffman, B., and Liebermann, D. A. p53 involvement in control of G2 exit of the cell cycle: role in DNA damage-induced apoptosis. Oncogene, 10: 2263-2270, 1995.
    • (1995) Oncogene , vol.10 , pp. 2263-2270
    • Guillouf, C.1    Rosselli, F.2    Krishnaraju, K.3    Moustacchi, E.4    Hoffman, B.5    Liebermann, D.A.6
  • 73
    • 0029881977 scopus 로고    scopus 로고
    • Abnormal centrosome amplification in the absence of p53
    • Washington DC
    • Fukasawa, K., Cho, T., Kuriyama, R., Rulong, S., and Vande Woude, G. F. Abnormal centrosome amplification in the absence of p53. Science (Washington DC), 271: 1744-1747, 1996.
    • (1996) Science , vol.271 , pp. 1744-1747
    • Fukasawa, K.1    Cho, T.2    Kuriyama, R.3    Rulong, S.4    Vande Woude, G.F.5
  • 74
    • 0029014496 scopus 로고
    • Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation
    • Terada, Y., Tatsuka, M., Jinno, S., and Okayama, H. Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation. Nature (Lond.), 376: 358-362, 1995.
    • (1995) Nature (Lond.) , vol.376 , pp. 358-362
    • Terada, Y.1    Tatsuka, M.2    Jinno, S.3    Okayama, H.4
  • 75
    • 0030159931 scopus 로고    scopus 로고
    • Accumulation of p16CDKN2A in response to ultraviolet irradiation correlates with late S-G(2)-phase cell cycle delay
    • Wang, X. Q., Gabrielli, B. G., Milligan, A., Dickinson, J. L., Antalis, T. M., and Ellem, K. A. Accumulation of p16CDKN2A in response to ultraviolet irradiation correlates with late S-G(2)-phase cell cycle delay. Cancer Res., 56: 2510-2514, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2510-2514
    • Wang, X.Q.1    Gabrielli, B.G.2    Milligan, A.3    Dickinson, J.L.4    Antalis, T.M.5    Ellem, K.A.6
  • 76
    • 0029909268 scopus 로고    scopus 로고
    • Delayed cyclin B1 expression during the G2 arrest following DNA damage
    • Maity, A., Hwang, A., Janss, A., Phillips, P., McKenna, W. G., and Muschel, R. J. Delayed cyclin B1 expression during the G2 arrest following DNA damage. Oncogene, 13: 1647-1657, 1996.
    • (1996) Oncogene , vol.13 , pp. 1647-1657
    • Maity, A.1    Hwang, A.2    Janss, A.3    Phillips, P.4    McKenna, W.G.5    Muschel, R.J.6
  • 77
    • 0028896811 scopus 로고
    • Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells
    • Maity, A., McKenna, W. G., and Muschel, R. J. Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells. EMBO J., 14: 603-609, 1995.
    • (1995) EMBO J. , vol.14 , pp. 603-609
    • Maity, A.1    McKenna, W.G.2    Muschel, R.J.3
  • 78
    • 0026485696 scopus 로고
    • Effects of ionizing radiation on cyclin expression in HeLa cells
    • Muschel, R. J., Zhang, H. B., Iliakis, G., and McKenna, W. G. Effects of ionizing radiation on cyclin expression in HeLa cells. Radial. Res., 132: 153-157, 1992.
    • (1992) Radial. Res. , vol.132 , pp. 153-157
    • Muschel, R.J.1    Zhang, H.B.2    Iliakis, G.3    McKenna, W.G.4
  • 80
    • 0026611089 scopus 로고
    • cdc2 tyrosine dephosphorylation, and mitotic progression in Chinese hamster ovary cells exposed to etoposide
    • cdc2 tyrosine dephosphorylation, and mitotic progression in Chinese hamster ovary cells exposed to etoposide. Cancer Res., 52: 1817-1822, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1817-1822
    • Lock, R.B.1
  • 83
    • 0028827848 scopus 로고
    • Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase
    • Herzinger, T., Funk, J. O., Hillmer, K., Eick, D., Wolf, D. A., and Kind, P. Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase. Oncogene, 11: 2151-2156, 1995.
    • (1995) Oncogene , vol.11 , pp. 2151-2156
    • Herzinger, T.1    Funk, J.O.2    Hillmer, K.3    Eick, D.4    Wolf, D.A.5    Kind, P.6
  • 84
    • 0028873880 scopus 로고
    • Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damase
    • Shimizu, T., O'Connor, P. M., Kohn, K. W., and Pommier, Y. Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damase. Cancer Res., 55: 228-231, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 228-231
    • Shimizu, T.1    O'Connor, P.M.2    Kohn, K.W.3    Pommier, Y.4
  • 85
    • 0029825066 scopus 로고    scopus 로고
    • Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells
    • Jin, P., Gu, Y., and Morgan, D. O. Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells. J. Cell Biol., 134: 963-970, 1996.
    • (1996) J. Cell Biol. , vol.134 , pp. 963-970
    • Jin, P.1    Gu, Y.2    Morgan, D.O.3
  • 87
    • 0031034628 scopus 로고    scopus 로고
    • Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast
    • Rhind, N., Furnari, B., and Russell, P. Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev., 11: 504-511, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 504-511
    • Rhind, N.1    Furnari, B.2    Russell, P.3
  • 88
    • 0031024274 scopus 로고    scopus 로고
    • 2-M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans
    • 2-M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans. EMBO J., 16: 182-192, 1997.
    • (1997) EMBO J. , vol.16 , pp. 182-192
    • Ye, X.S.1    Fincher, R.R.2    Tang, A.3    Osmani, S.A.4
  • 89
    • 0029664616 scopus 로고    scopus 로고
    • Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint
    • Washington DC
    • Walworth, N. C., and Bernards, R. rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science (Washington DC), 277: 353-356, 1996.
    • (1996) Science , vol.277 , pp. 353-356
    • Walworth, N.C.1    Bernards, R.2
  • 90
    • 0027202575 scopus 로고
    • Fission yeast wee1 protein kinase is not required for DNA damage-dependent mitotic arrest
    • Barbet, N. C., and Carr, A. M. Fission yeast wee1 protein kinase is not required for DNA damage-dependent mitotic arrest. Nature (Lond.), 364: 824-827, 1993.
    • (1993) Nature (Lond.) , vol.364 , pp. 824-827
    • Barbet, N.C.1    Carr, A.M.2
  • 91
    • 0026587204 scopus 로고
    • The wee1 protein kinase is required for radiation-induced mitotic delay
    • Rowley, R., Hudson, J., and Young, P. G. The wee1 protein kinase is required for radiation-induced mitotic delay. Nature (Lond.), 356: 353-355, 1992.
    • (1992) Nature (Lond.) , vol.356 , pp. 353-355
    • Rowley, R.1    Hudson, J.2    Young, P.G.3
  • 92
    • 0029379619 scopus 로고
    • The chk1 pathway is required to prevent mitosis following cell-cycle arrest at "start."
    • Carr, A. M., Moudjou, M., Bentley, N. J., and Hagan, I. M. The chk1 pathway is required to prevent mitosis following cell-cycle arrest at "start." Curr. Biol., 5: 1179-1190, 1995.
    • (1995) Curr. Biol. , vol.5 , pp. 1179-1190
    • Carr, A.M.1    Moudjou, M.2    Bentley, N.J.3    Hagan, I.M.4
  • 93
    • 0024959919 scopus 로고
    • Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
    • Gould, K. L., and Nurse, P. Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature (Lond.), 342: 39-45, 1989.
    • (1989) Nature (Lond.) , vol.342 , pp. 39-45
    • Gould, K.L.1    Nurse, P.2
  • 94
    • 0030008450 scopus 로고    scopus 로고
    • Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis
    • Ye, X. S., Fincher, R. R., Tang, A., O'Donnell, K., and Osmani, S. A. Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis. EMBO J., 15: 3599-3610, 1996.
    • (1996) EMBO J. , vol.15 , pp. 3599-3610
    • Ye, X.S.1    Fincher, R.R.2    Tang, A.3    O'Donnell, K.4    Osmani, S.A.5
  • 95
    • 0025021753 scopus 로고
    • Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
    • Enoch, T., and Nurse, P. Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell, 60: 665-673, 1990.
    • (1990) Cell , vol.60 , pp. 665-673
    • Enoch, T.1    Nurse, P.2
  • 96
    • 0025778595 scopus 로고
    • Coupling M phase and S phase: Controls maintaining the dependence of mitosis on chromosome replication
    • Enoch, T., and Nurse, P. Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell, 65: 921-923, 1991.
    • (1991) Cell , vol.65 , pp. 921-923
    • Enoch, T.1    Nurse, P.2
  • 97
    • 0029655570 scopus 로고    scopus 로고
    • Stockpiling of Cdc25 during a DNA replication checkpoint arrest in Schizosaccharomyces pombe
    • Kovelman, R., and Russell, P. Stockpiling of Cdc25 during a DNA replication checkpoint arrest in Schizosaccharomyces pombe. Mol. Cell. Biol., 16: 86-93, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 86-93
    • Kovelman, R.1    Russell, P.2
  • 98
    • 0029666459 scopus 로고    scopus 로고
    • p34cdc2 kinase activity is maintained upon activation of the replication checkpoint in Schizosaccharomyces pombe
    • Knudsen, K. E., Knudsen, E. S., Wang, J. Y. J., and Subramani, S. p34cdc2 kinase activity is maintained upon activation of the replication checkpoint in Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. USA, 93: 8278-8283, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8278-8283
    • Knudsen, K.E.1    Knudsen, E.S.2    Wang, J.Y.J.3    Subramani, S.4
  • 99
    • 0026610360 scopus 로고
    • CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae
    • CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae. Nature (Lond.), 355: 368-371, 1992.
    • (1992) Nature (Lond.) , vol.355 , pp. 368-371
    • Amon, A.1    Surana, U.2    Muroff, I.3    Nasmyth, K.4
  • 101
    • 0028915943 scopus 로고
    • A cell cycle checkpoint monitors cell morphogenesis in budding yeast
    • Lew, D. J., and Reed, S. I. A cell cycle checkpoint monitors cell morphogenesis in budding yeast. J. Cell Biol., 129: 739-749, 1995.
    • (1995) J. Cell Biol. , vol.129 , pp. 739-749
    • Lew, D.J.1    Reed, S.I.2
  • 102
    • 0025284348 scopus 로고
    • Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: Studies in Xenopus
    • Dasso, M., and Newport, J. W. Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus. Cell, 61: 811-823, 1990.
    • (1990) Cell , vol.61 , pp. 811-823
    • Dasso, M.1    Newport, J.W.2
  • 103
    • 0028998865 scopus 로고
    • Cell cycle regulation of a Xenopus Wee1-like kinase
    • Mueller, P. R., Coleman, T. R., and Dunphy, W. G. Cell cycle regulation of a Xenopus Wee1-like kinase. Mol. Biol. Cell, 6: 119-134, 1995.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 119-134
    • Mueller, P.R.1    Coleman, T.R.2    Dunphy, W.G.3
  • 104
    • 0029016412 scopus 로고
    • 2-M checkpoint with DNA synthesis inhibitors
    • 2-M checkpoint with DNA synthesis inhibitors. Mol. Biol. Cell, 6: 199-213, 1995.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 199-213
    • Kumagai, A.1    Dunphy, W.G.2
  • 106
    • 0023489384 scopus 로고
    • Periodic mitotic events induced in the absence of DNA replication
    • Schlegel, R., and Pardee, A. B. Periodic mitotic events induced in the absence of DNA replication. Proc. Natl. Acad. Sci. USA, 84: 9025-9029, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9025-9029
    • Schlegel, R.1    Pardee, A.B.2
  • 107
    • 0025695138 scopus 로고
    • Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells
    • Yamashita, K., Yasuda, H., Pines, J., Yasumoto, K., Nishitani, H., Ohtsubo, M., Hunter, T., Sugimura, T., and Nishimoto, T. Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J., 9: 4331-4338, 1990.
    • (1990) EMBO J. , vol.9 , pp. 4331-4338
    • Yamashita, K.1    Yasuda, H.2    Pines, J.3    Yasumoto, K.4    Nishitani, H.5    Ohtsubo, M.6    Hunter, T.7    Sugimura, T.8    Nishimoto, T.9
  • 108
    • 0030449425 scopus 로고    scopus 로고
    • p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine
    • DeFrank, J. S., Tang, W., and Powell, S. N. p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. Cancer Res., 56: 5365-5368, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 5365-5368
    • DeFrank, J.S.1    Tang, W.2    Powell, S.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.