-
1
-
-
0031587821
-
Recruitment of p300/CBP in p53-dependent signal pathways
-
1 Avantaggiati M. L., Ogryzko V., Gardner K., Giordano A., Levine A. S. and Kelly K. (1997) Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89: 1175-1184
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.S.5
Kelly, K.6
-
2
-
-
0030973238
-
Binding and modulation of p53 by p300/CBP coactivators
-
2 Lill N. L., Grossman S. R., Ginsberg D., DeCaprio J. and Livingston D. M. (1997) Binding and modulation of p53 by p300/CBP coactivators. Nature 387: 823-827
-
(1997)
Nature
, vol.387
, pp. 823-827
-
-
Lill, N.L.1
Grossman, S.R.2
Ginsberg, D.3
DeCaprio, J.4
Livingston, D.M.5
-
3
-
-
0028922929
-
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60
-
3 Thut C. J., Chen J. L., Klemm R. and Tjian R. (1994) p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science 267: 100-104
-
(1994)
Science
, vol.267
, pp. 100-104
-
-
Thut, C.J.1
Chen, J.L.2
Klemm, R.3
Tjian, R.4
-
4
-
-
0032518510
-
The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control
-
4 Garkavtsev I., Grigorian I. A., Ossovskaya V. S., Chernov M. V., Chumakov P. M. and Gudkov A. V. (1998) The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control. Nature 391: 295-298
-
(1998)
Nature
, vol.391
, pp. 295-298
-
-
Garkavtsev, I.1
Grigorian, I.A.2
Ossovskaya, V.S.3
Chernov, M.V.4
Chumakov, P.M.5
Gudkov, A.V.6
-
5
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
5 Haupt Y., Maya R., Kazaz A. and Oren M. (1997) Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
6
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
6 Kubbutat M. H., Jones S. N. and Vousden K. H. (1997) Regulation of p53 stability by Mdm2. Nature 387: 299-303
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
7
-
-
0026560995
-
Formation of stable p53 homotetramers and multiples of tetramers
-
7 Stenger J. E., Mayr G. A., Mann K. and Tegtmeyer P. (1992) Formation of stable p53 homotetramers and multiples of tetramers. Mol. Carcinog. 5: 102-106
-
(1992)
Mol. Carcinog.
, vol.5
, pp. 102-106
-
-
Stenger, J.E.1
Mayr, G.A.2
Mann, K.3
Tegtmeyer, P.4
-
9
-
-
0026849821
-
Definition of a consensus binding site for p53
-
9 El-Deiry W. S., Kern S. E., Pietenpol J. A., Kinzler K. W. and Vogelstein B. (1992) Definition of a consensus binding site for p53. Nature Genet. 1: 45-49
-
(1992)
Nature Genet.
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
10
-
-
0028943706
-
Interaction of p53 with its consensus DNA-binding site
-
10 Wang Y., Schwedes J. F., Parks D., Mann K. and Tegtmeyer P. (1995) Interaction of p53 with its consensus DNA-binding site. Mol. Cell. Biol. 15: 2157-2165
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2157-2165
-
-
Wang, Y.1
Schwedes, J.F.2
Parks, D.3
Mann, K.4
Tegtmeyer, P.5
-
11
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
11 El-Deiry W. S., Tokino T., Velculescu V. E., Levy D. B., Parsons R., Trent J. M. et al. (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
12
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 s defective in ataxiatelangiectasia
-
12 Kastan M. B., Zhan Q., el-Deiry W. S., Carrier F., Jacks T., Walsh W. V. et al. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 s defective in ataxiatelangiectasia. Cell 71: 587-597
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
-
13
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
13 Momand J., Zambetti G. P., Olson D. C., George D. and Levine A. J. (1992) The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69: 1237-1245
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
14
-
-
0028864667
-
Induction of the growth inhibitor IGF-binding protein 3 by p53
-
14 Buckbinder L., Talbott R., Velasco-Miguel S., Takenaka I., Faha B., Seizinger B. R. et al. (1995) Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 377: 646-649
-
(1995)
Nature
, vol.377
, pp. 646-649
-
-
Buckbinder, L.1
Talbott, R.2
Velasco-Miguel, S.3
Takenaka, I.4
Faha, B.5
Seizinger, B.R.6
-
15
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
15 Miyashita T. and Reed J. C. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
16
-
-
0028568315
-
Cell cycle control and cancer
-
16 Hartwell L. H. and Kastan M. B. (1994) Cell cycle control and cancer. Science 266: 1821-1828
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
17
-
-
0028145057
-
p53 tagged sites from human genomic DNA
-
17 Tokino T., Thiagalingam S., el-Deiry W. S., Waldman T., Kinzler K. W. and Vogelstein B. (1994) p53 tagged sites from human genomic DNA. Hum. Mol. Genet. 3: 1537-1542
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1537-1542
-
-
Tokino, T.1
Thiagalingam, S.2
El-Deiry, W.S.3
Waldman, T.4
Kinzler, K.W.5
Vogelstein, B.6
-
18
-
-
0030930366
-
A model for p53-induced apoptosis
-
18 Polyak K., Xia Y., Zweier J. L., Kinzler K. W. and Vogelstein B. (1997) A model for p53-induced apoptosis. Nature 389: 300-305
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
19
-
-
0031577506
-
Apoptosis. Clues in the p53 murder mystery
-
19 Wyllie A. (1997) Apoptosis. Clues in the p53 murder mystery. Nature 389: 237-238
-
(1997)
Nature
, vol.389
, pp. 237-238
-
-
Wyllie, A.1
-
20
-
-
0031026001
-
Further characterisation of the p53 responsive element-identification of new candidate genes for trans-activation by p53
-
20 Bourdon J. C., Deguin-Chambon V., Lelong J. C., Dessen P., May P., Debuire B. et al. (1997) Further characterisation of the p53 responsive element-identification of new candidate genes for trans-activation by p53. Oncogene 14: 85-94
-
(1997)
Oncogene
, vol.14
, pp. 85-94
-
-
Bourdon, J.C.1
Deguin-Chambon, V.2
Lelong, J.C.3
Dessen, P.4
May, P.5
Debuire, B.6
-
21
-
-
0028606859
-
p53 oligomerization and DNA looping are linked with transcriptional activation
-
21 Stenger J. E., Tegtmeyer P., Mayr G. A., Reed M., Wang Y., Wang P. et al. (1994) p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J. 13: 6011-6020
-
(1994)
EMBO J.
, vol.13
, pp. 6011-6020
-
-
Stenger, J.E.1
Tegtmeyer, P.2
Mayr, G.A.3
Reed, M.4
Wang, Y.5
Wang, P.6
-
22
-
-
0030783769
-
Tumor suppressor protein p53 binds preferentially to supercoiled DNA
-
22 Palecek E., Vlk D., Stankova V., Brazda V., Vojtesek B., Hupp T. R. et al. (1997) Tumor suppressor protein p53 binds preferentially to supercoiled DNA. Oncogene 15: 2201-2209
-
(1997)
Oncogene
, vol.15
, pp. 2201-2209
-
-
Palecek, E.1
Vlk, D.2
Stankova, V.3
Brazda, V.4
Vojtesek, B.5
Hupp, T.R.6
-
23
-
-
0026018256
-
A DNA binding domain is contained in the C-terminus of wild type p53 protein
-
23 Foord O. S., Bhattacharya P., Reich Z and Rotter V. (1991) A DNA binding domain is contained in the C-terminus of wild type p53 protein. Nucleic Acids Res. 19: 5191-5198
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 5191-5198
-
-
Foord, O.S.1
Bhattacharya, P.2
Reich, Z.3
Rotter, V.4
-
24
-
-
0027284915
-
p53-catalyzed annealing of complementary single-stranded nucleic acids
-
24 Oberosler P., Hloch P., Ramsperger U. and Stahl H. (1993) p53-catalyzed annealing of complementary single-stranded nucleic acids. EMBO J. 12: 2389-2396
-
(1993)
EMBO J.
, vol.12
, pp. 2389-2396
-
-
Oberosler, P.1
Hloch, P.2
Ramsperger, U.3
Stahl, H.4
-
25
-
-
0031557393
-
Mechanistic insights into p53-promoted RNA-RNA annealing
-
25 Nedbal W., Frey M., Willemann B., Zentgraf H. and Sczakiel G. (1997) Mechanistic insights into p53-promoted RNA-RNA annealing. J. Mol. Biol. 266: 677-687
-
(1997)
J. Mol. Biol.
, vol.266
, pp. 677-687
-
-
Nedbal, W.1
Frey, M.2
Willemann, B.3
Zentgraf, H.4
Sczakiel, G.5
-
26
-
-
0028862982
-
The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation
-
26 Reed M., Woelker B., Wang P., Wang Y., Anderson M. E. and Tegtmeyer P. (1995) The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation. Proc. Natl. Acad. Sci. USA 92: 9455-9459
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9455-9459
-
-
Reed, M.1
Woelker, B.2
Wang, P.3
Wang, Y.4
Anderson, M.E.5
Tegtmeyer, P.6
-
27
-
-
0029013273
-
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
-
27 Lee S., Elenbaas B., Levine A. and Griffith J. (1995) p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 81: 1013-1020
-
(1995)
Cell
, vol.81
, pp. 1013-1020
-
-
Lee, S.1
Elenbaas, B.2
Levine, A.3
Griffith, J.4
-
28
-
-
0030985675
-
Human p53 binds Holliday junctions strongly and facilitates their cleavage
-
28 Lee S., Cavallo L. and Griffith J. (1997) Human p53 binds Holliday junctions strongly and facilitates their cleavage. J. Biol. Chem. 272: 7532-7539
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7532-7539
-
-
Lee, S.1
Cavallo, L.2
Griffith, J.3
-
29
-
-
0028965832
-
Refined solution structure of the oligomerization domain of the tumour suppressor p53
-
29 Clore G. M., Ernst J., Clubb R., Omichinski J. G., Kennedy W. M., Sakaguchi K. et al. (1995) Refined solution structure of the oligomerization domain of the tumour suppressor p53. Nature Struct. Biol. 2: 321-333
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 321-333
-
-
Clore, G.M.1
Ernst, J.2
Clubb, R.3
Omichinski, J.G.4
Kennedy, W.M.5
Sakaguchi, K.6
-
30
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
-
30 Jeffrey P. D., Gorina S. and Pavletich N. P. (1995) Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science 267: 1498-1502
-
(1995)
Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
31
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
31 Kaghad M., Bonnet H., Yang A., Creancier L., Biscan J. C., Valent A. et al. (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90: 809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
-
32
-
-
0030884751
-
A novel protein with strong homology to the tumor suppressor p53
-
32 Schmale H. and Bamberger C. (1997) A novel protein with strong homology to the tumor suppressor p53. Oncogene 15: 1363-1367
-
(1997)
Oncogene
, vol.15
, pp. 1363-1367
-
-
Schmale, H.1
Bamberger, C.2
-
33
-
-
0028209857
-
Sequence-specific transcriptional activation is essential for growth suppression by p53
-
33 Pietenpol J. A., Tokino T., Thiagalingam S., el-Deiry W. S., Kinzler K. W. and Vogelstein B. (1994) Sequence-specific transcriptional activation is essential for growth suppression by p53. Proc. Natl. Acad. Sci. USA 91: 1998-2002
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1998-2002
-
-
Pietenpol, J.A.1
Tokino, T.2
Thiagalingam, S.3
El-Deiry, W.S.4
Kinzler, K.W.5
Vogelstein, B.6
-
34
-
-
0028888020
-
The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding
-
34 Waterman J. L., Shenk J. L. and Halazonetis T. D. (1995) The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding. EMBO J. 14: 512-519
-
(1995)
EMBO J.
, vol.14
, pp. 512-519
-
-
Waterman, J.L.1
Shenk, J.L.2
Halazonetis, T.D.3
-
35
-
-
0030722137
-
Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain
-
35 McCoy M., Stavridi E. S., Waterman J. L., Wieczorek A. M., Opella S. J. and Halazonetis T. D. (1997) Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain. EMBO J. 16: 6230-6236
-
(1997)
EMBO J.
, vol.16
, pp. 6230-6236
-
-
McCoy, M.1
Stavridi, E.S.2
Waterman, J.L.3
Wieczorek, A.M.4
Opella, S.J.5
Halazonetis, T.D.6
-
36
-
-
0028845158
-
Small peptides activate the latent sequence-specific DNA binding function of p53
-
36 Hupp T. R., Sparks A. and Lane D. P. (1995) Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 83: 237-245
-
(1995)
Cell
, vol.83
, pp. 237-245
-
-
Hupp, T.R.1
Sparks, A.2
Lane, D.P.3
-
37
-
-
0027250493
-
Activation of the cryptic DNA binding function of mutant forms of p53
-
37 Hupp T. R., Meek D. W., Midgley C. A. and Lane D. P. (1993) Activation of the cryptic DNA binding function of mutant forms of p53. Nucleic Acids Res. 21: 3167-3174
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3167-3174
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
38
-
-
0028519273
-
Allosteric activation of latent p53 tetramers
-
38 Hupp T. R. and Lane D. P. (1994) Allosteric activation of latent p53 tetramers. Curr. Biol. 4: 865-875
-
(1994)
Curr. Biol.
, vol.4
, pp. 865-875
-
-
Hupp, T.R.1
Lane, D.P.2
-
39
-
-
0029003061
-
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
-
39 Wang Y. and Prives C. (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature 376: 88-91
-
(1995)
Nature
, vol.376
, pp. 88-91
-
-
Wang, Y.1
Prives, C.2
-
40
-
-
0030790778
-
Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53
-
40 Sakaguchi K., Sakamoto H., Lewis M. S., Anderson C. W., Erickson J. W., Appella E. et al. (1997) Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. Biochemistry 36: 10117-10124
-
(1997)
Biochemistry
, vol.36
, pp. 10117-10124
-
-
Sakaguchi, K.1
Sakamoto, H.2
Lewis, M.S.3
Anderson, C.W.4
Erickson, J.W.5
Appella, E.6
-
41
-
-
0026448672
-
Regulation of the specific DNA binding function of p53
-
41 Hupp T. R., Meek D. W., Midgley C. A. and Lane D. P. (1992) Regulation of the specific DNA binding function of p53. Cell 71: 875-886
-
(1992)
Cell
, vol.71
, pp. 875-886
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
42
-
-
0029846879
-
Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70
-
42 Hansen S., Midgley C. A., Lane D. P., Freeman B. C., Morimoto R. I. and Hupp T. R. (1996) Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70. J. Biol. Chem. 271: 30922-30928
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30922-30928
-
-
Hansen, S.1
Midgley, C.A.2
Lane, D.P.3
Freeman, B.C.4
Morimoto, R.I.5
Hupp, T.R.6
-
43
-
-
0027459198
-
mdm2 expression is induced by wild type p53 activity
-
43 Barak Y., Juven T., Haffner R. and Oren M. (1997) mdm2 expression is induced by wild type p53 activity. EMBO J. 12: 461-468
-
(1997)
EMBO J.
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
44
-
-
0030022559
-
Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins
-
44 Hansen S., Hupp T. R. and Lane D. P. (1996) Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. J. Biol. Chem. 271: 3917-3924
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3917-3924
-
-
Hansen, S.1
Hupp, T.R.2
Lane, D.P.3
-
45
-
-
0029815092
-
Regulation of mutant p53 temperature-sensitive DNA binding
-
45 Friedlander P., Legros Y., Soussi T. and Prives C. (1996) Regulation of mutant p53 temperature-sensitive DNA binding. J. Biol. Chem. 271: 25468-25478
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25468-25478
-
-
Friedlander, P.1
Legros, Y.2
Soussi, T.3
Prives, C.4
-
46
-
-
0030877395
-
Functional dissection of p53 tumor suppressor protein
-
46 Jayaraman L., Freulich E. and Prives C. (1997) Functional dissection of p53 tumor suppressor protein. Methods Enzymol. 283: 245-256
-
(1997)
Methods Enzymol.
, vol.283
, pp. 245-256
-
-
Jayaraman, L.1
Freulich, E.2
Prives, C.3
-
47
-
-
0022637380
-
Specific interaction between the p53 cellular tumour antigen and major heat shock proteins
-
47 Pinhasi-Kimhi O., Michalovitz D., Ben-Zeev A. and Oren M. (1986) Specific interaction between the p53 cellular tumour antigen and major heat shock proteins. Nature 320: 182-184
-
(1986)
Nature
, vol.320
, pp. 182-184
-
-
Pinhasi-Kimhi, O.1
Michalovitz, D.2
Ben-Zeev, A.3
Oren, M.4
-
48
-
-
0028837979
-
Interaction between hsp70 and hsp40. Eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53
-
48 Sugito K., Yamane M., Hattori H., Hayashi Y., Tohnai I., Ueda M. et al. (1995) Interaction between hsp70 and hsp40. eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53. FFBS Lett. 358: 161-164
-
(1995)
FFBS Lett.
, vol.358
, pp. 161-164
-
-
Sugito, K.1
Yamane, M.2
Hattori, H.3
Hayashi, Y.4
Tohnai, I.5
Ueda, M.6
-
49
-
-
15844363948
-
Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell
-
49 Sepehrnia B., Paz I. B., Dasgupta G. and Momand J. (1996) Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell. J. Biol. Chem. 271: 15084-15090
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15084-15090
-
-
Sepehrnia, B.1
Paz, I.B.2
Dasgupta, G.3
Momand, J.4
-
50
-
-
0029887140
-
The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding
-
50 Freeman B. C. and Morimoto R. I. (1996) The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding. EMBO J. 15: 2969-2979
-
(1996)
EMBO J.
, vol.15
, pp. 2969-2979
-
-
Freeman, B.C.1
Morimoto, R.I.2
-
51
-
-
0031453994
-
Induction of heat shock protein 70 protects thymocytes against radiation-induced apoptosis
-
51 Gordon S. A., Hoffman R. A., Simmons R. L. and Ford H. R. (1997) Induction of heat shock protein 70 protects thymocytes against radiation-induced apoptosis. Arch. Surg. 132: 1277-1282
-
(1997)
Arch. Surg.
, vol.132
, pp. 1277-1282
-
-
Gordon, S.A.1
Hoffman, R.A.2
Simmons, R.L.3
Ford, H.R.4
-
52
-
-
0030014643
-
Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1-and staurosporine-induced cell death
-
52 Mehlen P., Schulze-Osthoff K. and Arrigo A. P. (1996) Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1-and staurosporine-induced cell death. J. Biol. Chem. 271: 16510-16514
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16510-16514
-
-
Mehlen, P.1
Schulze-Osthoff, K.2
Arrigo, A.P.3
-
53
-
-
0029947822
-
Mitochondria are selective targets for the protective effects of heat shock against oxidative injury
-
53 Polla B. S., Kantengwa S., Francois D., Salvioli S., Franceschi C., Marsac C. et al. (1996) Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. Proc. Natl. Acad. Sci. USA 93: 6458-6463
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6458-6463
-
-
Polla, B.S.1
Kantengwa, S.2
Francois, D.3
Salvioli, S.4
Franceschi, C.5
Marsac, C.6
-
54
-
-
0029886404
-
Apoptosis in heat-induced cell killing: The protective role of hsp-70 and the sensitization effect of the c-myc gene
-
54 Li W. X., Chen C. H., Ling C. C. and Li G. C. (1996) Apoptosis in heat-induced cell killing: the protective role of hsp-70 and the sensitization effect of the c-myc gene. Radiat. Res. 145: 324-330
-
(1996)
Radiat. Res.
, vol.145
, pp. 324-330
-
-
Li, W.X.1
Chen, C.H.2
Ling, C.C.3
Li, G.C.4
-
55
-
-
0025248598
-
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form
-
55 Gannon J. V., Greaves R., Iggo R. and Lane D. P. (1990) Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J. 9: 1595-1602
-
(1990)
EMBO J.
, vol.9
, pp. 1595-1602
-
-
Gannon, J.V.1
Greaves, R.2
Iggo, R.3
Lane, D.P.4
-
56
-
-
0030852889
-
HSP70 binding sites in the tumor suppressor protein p53
-
56 Fourie A. M., Hupp T. R., Lane D. P., Sang B. C., Barbosa M. S., Sambrook J. F. et al. (1997) HSP70 binding sites in the tumor suppressor protein p53. J. Biol. Chem. 272: 19471-19479
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19471-19479
-
-
Fourie, A.M.1
Hupp, T.R.2
Lane, D.P.3
Sang, B.C.4
Barbosa, M.S.5
Sambrook, J.F.6
-
57
-
-
0027246716
-
Regulation of p53 protein expression in human breast cancer cell lines
-
57 Vojtesek B. and Lane D. P. (1993) Regulation of p53 protein expression in human breast cancer cell lines. J. Cell Sci. 105: 607-612
-
(1993)
J. Cell Sci.
, vol.105
, pp. 607-612
-
-
Vojtesek, B.1
Lane, D.P.2
-
58
-
-
0031447171
-
Thermodynamic stability of wild-type and mutant p53 core domain
-
58 Bullock A. N., Henckel J., DeDecker B. S., Johnson C. M., Nikolova P. V., Proctor M. R. et al. (1997) Thermodynamic stability of wild-type and mutant p53 core domain. Proc. Natl. Acad. Sci. USA 94: 14338-14342
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14338-14342
-
-
Bullock, A.N.1
Henckel, J.2
DeDecker, B.S.3
Johnson, C.M.4
Nikolova, P.V.5
Proctor, M.R.6
-
59
-
-
0030896451
-
Correcting temperature-sensitive protein folding defects
-
59 Brown C. R., Hong-Brown L. Q. and Welch W. J. (1997) Correcting temperature-sensitive protein folding defects. J. Clin. Invest. 99: 1432-1444
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1432-1444
-
-
Brown, C.R.1
Hong-Brown, L.Q.2
Welch, W.J.3
-
60
-
-
0014847819
-
Geldanamycin, a new antibiotic
-
60 DeBoer C., Meulman P. A., Wnuk R. J. and Peterson D. H. (1970) Geldanamycin, a new antibiotic. J. Antibiot. (Tokyo) 23: 442-447
-
(1970)
J. Antibiot. (Tokyo)
, vol.23
, pp. 442-447
-
-
DeBoer, C.1
Meulman, P.A.2
Wnuk, R.J.3
Peterson, D.H.4
-
61
-
-
0028786332
-
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
-
61 Schulte T. W., Blagosklonny M. V., Ingui C. and Neckers L. (1995) Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J. Biol. Chem. 270: 24585-24588
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24585-24588
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Ingui, C.3
Neckers, L.4
-
62
-
-
0030612135
-
Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity
-
62 An W. G., Schnur R. C., Neckers L. and Blagosklonny M. V. (1997) Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity. Cancer Chemother. Pharmacol. 40: 60-64
-
(1997)
Cancer Chemother. Pharmacol.
, vol.40
, pp. 60-64
-
-
An, W.G.1
Schnur, R.C.2
Neckers, L.3
Blagosklonny, M.V.4
-
63
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
-
63 Stebbins C. E., Russo A. A., Schneider C., Rosen N., Hartl F. U. and Pavletich N. P. (1997) Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell 89: 239-250
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
64
-
-
0029145215
-
Geldanamycin selectively destabilizes and conformationally alters mutated p53
-
64 Blagosklonny M. V., Toretsky J. and Neckers L. (1995) Geldanamycin selectively destabilizes and conformationally alters mutated p53. Oncogene 11: 933-939
-
(1995)
Oncogene
, vol.11
, pp. 933-939
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Neckers, L.3
-
65
-
-
0030878952
-
Geldanamycin stimulated destabilization of mutated p53 is mediated by the proteasome in vivo
-
65 Whitesell L., Sutphin P., An W. G., Schulte T., Blagosklonny M. V. et al. (1997) Geldanamycin stimulated destabilization of mutated p53 is mediated by the proteasome in vivo. Oncogene 14: 2809-2816
-
(1997)
Oncogene
, vol.14
, pp. 2809-2816
-
-
Whitesell, L.1
Sutphin, P.2
An, W.G.3
Schulte, T.4
Blagosklonny, M.V.5
-
66
-
-
0029737509
-
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90
-
66 Blagosklonny M. V., Toretsky J., Bohen S. and Neckers L. (1996) Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90. Proc. Natl. Acad. Sci. USA 93: 8379-8383
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8379-8383
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Bohen, S.3
Neckers, L.4
-
67
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
67 Lane D. P. and Crawford L. V. (1979) T antigen is bound to a host protein in SV40-transformed cells. Nature 278: 261-263
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.P.1
Crawford, L.V.2
-
68
-
-
0018760324
-
Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
-
68 Linzer D. I. and Levine A. J. (1979) Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 17: 43-52
-
(1979)
Cell
, vol.17
, pp. 43-52
-
-
Linzer, D.I.1
Levine, A.J.2
-
69
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
69 DeCaprio J. A., Ludlow J. W., Figge J., Shew J. Y., Huang C. M., Lee W. H. et al. (1988) SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54: 275-283
-
(1988)
Cell
, vol.54
, pp. 275-283
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
Shew, J.Y.4
Huang, C.M.5
Lee, W.H.6
-
70
-
-
0029940386
-
Association of p300 and CBP with simian virus 40 large T antigen
-
70 Eckner R., Ludlow J. W., Lill N. L., Oldread E., Arany Z., Modjtahedi N. et al. (1996) Association of p300 and CBP with simian virus 40 large T antigen. Mol. Cell. Biol. 16: 3454-3464
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3454-3464
-
-
Eckner, R.1
Ludlow, J.W.2
Lill, N.L.3
Oldread, E.4
Arany, Z.5
Modjtahedi, N.6
-
71
-
-
0030935256
-
The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone
-
71 Kelley W. L. and Georgopoulos C. (1997) The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone. Proc. Natl. Acad. Sci. USA 94: 3679-3684
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3679-3684
-
-
Kelley, W.L.1
Georgopoulos, C.2
-
72
-
-
0030842474
-
The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain
-
72 Srinivasan A., McClellan A. J., Vartikar J., Marks I., Cantalupo P., Li Y. et al. (1997) The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. Mol. Cell. Biol. 17: 4761-4773
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4761-4773
-
-
Srinivasan, A.1
McClellan, A.J.2
Vartikar, J.3
Marks, I.4
Cantalupo, P.5
Li, Y.6
-
73
-
-
0029928512
-
Modification of an N-terminal regulatory domain of T antigen restores p53-T antigen complex formation in the absence of an essential metal ion cofactor
-
73 Kernohan N. M., Hupp T. R. and Lane D. P. (1996) Modification of an N-terminal regulatory domain of T antigen restores p53-T antigen complex formation in the absence of an essential metal ion cofactor. J. Biol. Chem. 271: 4954-4960
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4954-4960
-
-
Kernohan, N.M.1
Hupp, T.R.2
Lane, D.P.3
-
74
-
-
0030812552
-
The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function
-
74 Sheng Q., Denis D., Ratnofsky M., Roberts T. M., DeCaprio J. A. and Schaffhausen B. (1997) The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function. J. Virol. 71: 9410-9416
-
(1997)
J. Virol.
, vol.71
, pp. 9410-9416
-
-
Sheng, Q.1
Denis, D.2
Ratnofsky, M.3
Roberts, T.M.4
DeCaprio, J.A.5
Schaffhausen, B.6
-
75
-
-
0030961889
-
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
-
75 Selivanova G., Iotsova V., Okan I., Fritsche M., Strom M., Groner B. et al. (1997) Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain. Nature Med. 3: 632-638
-
(1997)
Nature Med.
, vol.3
, pp. 632-638
-
-
Selivanova, G.1
Iotsova, V.2
Okan, I.3
Fritsche, M.4
Strom, M.5
Groner, B.6
-
76
-
-
0029027040
-
Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner
-
76 Hupp T. R. and Lane D. P. (1995) Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner. J. Biol. Chem. 270: 18165-18174
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18165-18174
-
-
Hupp, T.R.1
Lane, D.P.2
-
77
-
-
0032495575
-
Fine mapping and regulation of the association of p53 with p34CDC2
-
77 Wagner P., Fuchs A., Gotz C., Nastainczyk W. and Montenarh M. (1998) Fine mapping and regulation of the association of p53 with p34CDC2. Oncogene 16: 105-111
-
(1998)
Oncogene
, vol.16
, pp. 105-111
-
-
Wagner, P.1
Fuchs, A.2
Gotz, C.3
Nastainczyk, W.4
Montenarh, M.5
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