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Volumn 60, Issue 4, 2000, Pages 531-545

Signaling pathways mediating anti-apoptotic action of neurotphins

Author keywords

Akt; Apoptosis; BDNF; Extracellular signal regulated kinase; Glycogen synthase kinase 3 ; Neurons; NGF; Phosphatidylinositol 3 kinase; Signal transduction

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 0033672628     PISSN: 00651400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (93)

References (132)
  • 5
    • 0033556356 scopus 로고    scopus 로고
    • A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside
    • (1999) J. Neurosci. , vol.19 , pp. 664-673
    • Anderson, C.N.G.1    Tolkovsky, A.M.2
  • 8
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
    • (1993) Biochem. J. , vol.296 , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 10
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • (1989) Neuron , vol.2 , pp. 1525-1534
    • Barde, Y.A.1
  • 29
    • 0032522924 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons
    • (1998) J. Neurosci. , vol.18 , pp. 2933-2943
    • Crowder, R.J.1    Freeman, R.S.2
  • 30
    • 0032788544 scopus 로고    scopus 로고
    • The survival of sympathetic neurons promoted by potassium depolarization, but not by cyclic AMP, requires phosphatidylinositol 3-kinase and Akt
    • (1999) J. Neurochem. , vol.73 , pp. 466-475
    • Crowder, R.J.1    Freeman, R.S.2
  • 31
    • 0031054670 scopus 로고    scopus 로고
    • Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI 3-kinase in IGF-1 signaling
    • (1997) J. Neurosci. , vol.17 , pp. 1548-1560
    • D'Mello, S.R.1    Borodezt, K.2    Soltoff, S.P.3
  • 41
    • 0032846284 scopus 로고    scopus 로고
    • Extracellular-regulated kinases and phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor-mediated survival and neuritogenesis of the neuroblastoma cell line SH-SY5Y
    • (1999) J. Neurochem. , vol.73 , pp. 1409-1421
    • Encinas, M.1    Iglesias, M.2    Llecha, N.3    Comella, J.X.4
  • 49
    • 0029892754 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase
    • (1996) J. Biol. Chem. , vol.271 , pp. 14560-14566
    • Gardner, A.M.1    Johnson, G.L.2
  • 53
    • 0031005028 scopus 로고    scopus 로고
    • Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases
    • (1997) Oncogene , vol.14 , pp. 1635-1642
    • Grammer, T.C.1    Blenis, J.2
  • 59
    • 0032919249 scopus 로고    scopus 로고
    • An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons
    • (1999) Jpn. J. Pharmacol. , vol.79 , pp. 369-378
    • Harada, J.1    Sugimoto, M.2
  • 61
    • 0031053360 scopus 로고    scopus 로고
    • Signal transduction - Akt signaling: Linking membrane events to life and death decisions
    • (1997) Science , vol.275 , pp. 628-630
    • Hemmings, B.A.1
  • 73
    • 0032535276 scopus 로고    scopus 로고
    • p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons
    • (1998) J. Neurosci. , vol.18 , pp. 10420-10428
    • Klesse, L.J.1    Parada, L.F.2
  • 75
    • 0029904388 scopus 로고    scopus 로고
    • Neurotrophins and Alzheimer's disease: Beyond the cholinergic neurons
    • (1996) Life Sci. , vol.58 , pp. 2019-2027
    • Knusel, B.1    Gao, H.2
  • 77
    • 0032582793 scopus 로고    scopus 로고
    • Ras promotes cell survival in Drosophila by downregulating hid expression
    • (1998) Cell , vol.95 , pp. 319-329
    • Kurada, P.1    White, K.2
  • 80
    • 0028113573 scopus 로고
    • Role of neurotrophins in preventing glutamate induced neuronal cell death
    • (1994) J. Neurol. , vol.242
    • Lindholm, D.1
  • 81
    • 0028262267 scopus 로고
    • Neurotrophic growth factors and neurodegenerative diseases: Therapeutic potential of the neurotrophins and ciliary neurotrophic factor
    • (1994) Neurobiol. Aging , vol.15 , pp. 249-251
    • Lindsay, R.M.1
  • 89
    • 0029964851 scopus 로고    scopus 로고
    • Signal transduction through beta-catenin and specification of cell fate during embryogenesis
    • (1996) Genes. Dev. , vol.10 , pp. 2527-2539
    • Miller, J.R.1    Moon, R.T.2
  • 92
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • (1996) J. Cell. Biol. , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 96
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3- Kinase/Akt cell survival pathway
    • (1998) J. Biol. Chem. , vol.273 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 97
    • 0001482329 scopus 로고    scopus 로고
    • Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: Its role in zinc-induced neuronal death
    • (1999) J. Neurochem. , vol.73 , pp. 450-456
    • Park, J.A.1    Koh, J.Y.2
  • 99
    • 0033565418 scopus 로고    scopus 로고
    • 2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase- dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons
    • (1999) J. Neurosci. , vol.19 , pp. 5861-5874
    • Perkinton, M.S.1    Sihra, T.S.2    Williams, R.J.3
  • 113
  • 120
    • 0031027331 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway
    • (1997) J. Neurosci. , vol.17 , pp. 83-90
    • Villalba, M.1    Journot, L.2
  • 121
    • 0029800940 scopus 로고    scopus 로고
    • Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD48059 does not suppress nerve growth factor-induced survival of sympathetic neurones
    • (1996) J. Neurochem. , vol.67 , pp. 1801-1805
    • Virdee, K.1    Tolkovsky, A.M.2
  • 128
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 130
    • 0032500670 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate inhibits apoptosis through activation of phosphatidylinositol 3-kinase in cerebellar granule neurons. A role for insulin receptor substrate-1 in the neurotrophic action of n-methyl-D-aspartate and its inhibition by ethanol
    • (1998) J. Biol. Chem. , vol.273 , pp. 26596-26602
    • Zhang, F.X.1    Rubin, R.2    Rooney, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.