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Volumn 19, Issue 7, 1999, Pages 2455-2463

The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons

Author keywords

Estrogen; Excitotoxicity; GAP; Growth factors; MAPK; Neuroprotection; src

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR;

EID: 0033118665     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-07-02455.1999     Document Type: Article
Times cited : (549)

References (45)
  • 1
    • 0029120606 scopus 로고
    • An antiestrogen: A phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor
    • Arnold SF, Notides AC (1995) An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor. Proc Natl Acad Sci USA 92:7475-7479.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7475-7479
    • Arnold, S.F.1    Notides, A.C.2
  • 2
    • 0028833473 scopus 로고
    • Phosphorylation of the human estrogen receptor on tyrosine 537 in vivo and by src family tyrosine kinases in vitro
    • Arnold SF, Obourn JO, Jaffe HJ, Notides AC (1995) Phosphorylation of the human estrogen receptor on tyrosine 537 in vivo and by src family tyrosine kinases in vitro. Mol Endocrinol 9:24-33.
    • (1995) Mol Endocrinol , vol.9 , pp. 24-33
    • Arnold, S.F.1    Obourn, J.O.2    Jaffe, H.J.3    Notides, A.C.4
  • 3
    • 0027964862 scopus 로고
    • Estrogen action via the cAMP signaling pathway: Stimulation of adenylate cyclase and cAMP-regulated gene transcription
    • Aronica SM, Kraus WL, Katzenellenbogen BS (1994) Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc Natl Acad Sci USA 91:8517-8521.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8517-8521
    • Aronica, S.M.1    Kraus, W.L.2    Katzenellenbogen, B.S.3
  • 4
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid β protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D (1994) Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77:817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 5
    • 0028971169 scopus 로고
    • 17β-estradiol protects neurons from oxidative stress-induced cell death in vitro
    • Behl C, Widmann M, Trapp T, Holsboer F (1995) 17β-estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun 216:473-482.
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 6
    • 0030921159 scopus 로고    scopus 로고
    • Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro
    • Braunton JL, Wong V, Wang W, Salter MW, Roder J, Liu M, Wang YT (1998) Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro. Neuroscience 82:161-170.
    • (1998) Neuroscience , vol.82 , pp. 161-170
    • Braunton, J.L.1    Wong, V.2    Wang, W.3    Salter, M.W.4    Roder, J.5    Liu, M.6    Wang, Y.T.7
  • 8
    • 0028321583 scopus 로고
    • Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury
    • Cheng B, Goodman Y, Begley JG, Mattson MP (1994) Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury. Brain Res 650:331-335.
    • (1994) Brain Res , vol.650 , pp. 331-335
    • Cheng, B.1    Goodman, Y.2    Begley, J.G.3    Mattson, M.P.4
  • 9
    • 0021961417 scopus 로고
    • Glutamate neurotoxicity in cortical cell culture is calcium dependent
    • Choi DW (1985) Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci Lett 58:293-297.
    • (1985) Neurosci Lett , vol.58 , pp. 293-297
    • Choi, D.W.1
  • 10
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi DW (1987) Ionic dependence of glutamate neurotoxicity. J Neurosci 7:369-379.
    • (1987) J Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 11
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW (1992) Excitotoxic cell death. J Neurobiol 23:1261-1276.
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 12
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell cultures: Attenuation by NMDA antagonists
    • Choi DW, Koh JY, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell cultures: attenuation by NMDA antagonists. J Neurosci 7:185-196.
    • (1988) J Neurosci , vol.7 , pp. 185-196
    • Choi, D.W.1    Koh, J.Y.2    Peters, S.3
  • 14
    • 0027910431 scopus 로고
    • Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
    • Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg R (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363:45-51.
    • (1993) Nature , vol.363 , pp. 45-51
    • Egan, S.E.1    Giddings, B.W.2    Brooks, M.W.3    Buday, L.4    Sizeland, A.M.5    Weinberg, R.6
  • 15
    • 0028030144 scopus 로고
    • Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats
    • Gibbs RB, Wu D, Hersh LB, Pfaff DW (1994) Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats. Exp Neurol 129:70-80.
    • (1994) Exp Neurol , vol.129 , pp. 70-80
    • Gibbs, R.B.1    Wu, D.2    Hersh, L.B.3    Pfaff, D.W.4
  • 16
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
    • Goodman Y, Bruce AJ, Cheng B, Mattson MP (1996) Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons. J Neurochem 66:1836-1844.
    • (1996) J Neurochem , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 17
    • 0030575880 scopus 로고    scopus 로고
    • Estradiol protects against β-amyloid (25-35) induced toxicity in SK-N-SH human neuroblastoma cells
    • Green PS, Gridley KE, Simpkins JW (1996) Estradiol protects against β-amyloid (25-35) induced toxicity in SK-N-SH human neuroblastoma cells. Neurosci Lett 218:165-168.
    • (1996) Neurosci Lett , vol.218 , pp. 165-168
    • Green, P.S.1    Gridley, K.E.2    Simpkins, J.W.3
  • 18
    • 0031555397 scopus 로고    scopus 로고
    • Low concentrations of estradiol reduce β-amyloid toxicity, lipid peroxidation and glucose utilization in human SK-N-Sh neuroblastoma cells
    • Gridley KE, Green PS, Simpkins JW (1997) Low concentrations of estradiol reduce β-amyloid toxicity, lipid peroxidation and glucose utilization in human SK-N-Sh neuroblastoma cells. Brain Res 778:158-165.
    • (1997) Brain Res , vol.778 , pp. 158-165
    • Gridley, K.E.1    Green, P.S.2    Simpkins, J.W.3
  • 19
    • 0029969410 scopus 로고    scopus 로고
    • 17β-estradiol potentiates kainate-induced currents via activation of the cAMP cascade
    • Gu Q, Moss RL (1996) 17β-estradiol potentiates kainate-induced currents via activation of the cAMP cascade. J Neurosci 16:3620-3629.
    • (1996) J Neurosci , vol.16 , pp. 3620-3629
    • Gu, Q.1    Moss, R.L.2
  • 21
    • 0022486717 scopus 로고
    • Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections
    • Hefti F (1986) Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. J Neurosci 6:2155-2162.
    • (1986) J Neurosci , vol.6 , pp. 2155-2162
    • Hefti, F.1
  • 22
    • 0028086440 scopus 로고
    • Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects
    • Henderson VW, Paganini Hill A, Emanuel CK, Dunn ME, Buckwalter JG (1994) Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects. Arch Neurol 51:896-900.
    • (1994) Arch Neurol , vol.51 , pp. 896-900
    • Henderson, V.W.1    Paganini Hill, A.2    Emanuel, C.K.3    Dunn, M.E.4    Buckwalter, J.G.5
  • 24
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore longitudinal study of aging
    • Kawas C, Resnick S, Morrison A, Brookmeyer R, Corrada M, Zonderman A, Bacal C, Lingle DD, Metter E (1997) A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore longitudinal study of aging. Neurology 48:1517-1521.
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3    Brookmeyer, R.4    Corrada, M.5    Zonderman, A.6    Bacal, C.7    Lingle, D.D.8    Metter, E.9
  • 25
    • 0023067115 scopus 로고
    • Nerve growth factor treatment after brain injury prevents neuronal death
    • Kromer LF (1987) Nerve growth factor treatment after brain injury prevents neuronal death. Science 235:216-218.
    • (1987) Science , vol.235 , pp. 216-218
    • Kromer, L.F.1
  • 26
    • 0028113573 scopus 로고
    • Role of neurotrophins in preventing glutamate induced neuronal cell death
    • Lindholm D (1994) Role of neurotrophins in preventing glutamate induced neuronal cell death. J Neurol 241:S16-S18.
    • (1994) J Neurol , vol.241
    • Lindholm, D.1
  • 27
    • 0029915861 scopus 로고    scopus 로고
    • Effects of ovariectomy and estrogen replacement on trkA and choline acetyltransferase mRNA expression in the rat basal forebrain
    • McMillan PJ, Singer CA, Dorsa DM (1996) Effects of ovariectomy and estrogen replacement on trkA and choline acetyltransferase mRNA expression in the rat basal forebrain. J Neurosci 16:1860-1865.
    • (1996) J Neurosci , vol.16 , pp. 1860-1865
    • McMillan, P.J.1    Singer, C.A.2    Dorsa, D.M.3
  • 28
    • 0030026862 scopus 로고    scopus 로고
    • Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor
    • Mermelstein PJ, Becker JB, Surmeier DJ (1996) Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor. J Neurosci 16:595-604.
    • (1996) J Neurosci , vol.16 , pp. 595-604
    • Mermelstein, P.J.1    Becker, J.B.2    Surmeier, D.J.3
  • 32
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks differentiation of PC-12 cells induced by nerve growth factor
    • Pang L, Sawada T, Decker SJ, Saltiel AR (1995) Inhibition of MAP kinase kinase blocks differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem 270:13585-13588.
    • (1995) J Biol Chem , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 33
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9:726-735.
    • (1995) FASEB J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 34
    • 0027043103 scopus 로고
    • Purification and characterization of mitogen-activated protein kinase activators from epidermal growth factor-stimulated A431 cells
    • Seger R, Ahn NG, Posada J, Munar ES, Jensen AM, Cooper JA, Cobb MH, Krebs EG (1992) Purification and characterization of mitogen-activated protein kinase activators from epidermal growth factor-stimulated A431 cells. J Biol Chem 267:25628-25631.
    • (1992) J Biol Chem , vol.267 , pp. 25628-25631
    • Seger, R.1    Ahn, N.G.2    Posada, J.3    Munar, E.S.4    Jensen, A.M.5    Cooper, J.A.6    Cobb, M.H.7    Krebs, E.G.8
  • 35
    • 0030570392 scopus 로고    scopus 로고
    • Estrogen protects primary cortical neurons from glutamate neurotoxicity
    • Singer CA, Rogers KL, Strickland TM, Dorsa DM (1996) Estrogen protects primary cortical neurons from glutamate neurotoxicity. Neurosci Lett 212:13-16.
    • (1996) Neurosci Lett , vol.212 , pp. 13-16
    • Singer, C.A.1    Rogers, K.L.2    Strickland, T.M.3    Dorsa, D.M.4
  • 36
    • 0032479933 scopus 로고    scopus 로고
    • Modulation of Bcl-2 expression: A potential component of estrogen neuroprotection in NT2 neurons
    • Singer CA, Rogers KL, Dorsa DM (1998) Modulation of Bcl-2 expression: a potential component of estrogen neuroprotection in NT2 neurons. NeuroReport 9:2565-2568.
    • (1998) NeuroReport , vol.9 , pp. 2565-2568
    • Singer, C.A.1    Rogers, K.L.2    Dorsa, D.M.3
  • 37
    • 0028918161 scopus 로고
    • The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague Dawley rats
    • Singh M, Meyer EM, Simpkins JW (1995) The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague Dawley rats. Endocrinology 136:2320-2324.
    • (1995) Endocrinology , vol.136 , pp. 2320-2324
    • Singh, M.1    Meyer, E.M.2    Simpkins, J.W.3
  • 38
    • 0344097487 scopus 로고    scopus 로고
    • Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: Convergence of estrogen and neurotrophin signaling pathways
    • Singh M, Sétáló Jr G, Guan X, Warren M, Toran-Allerand CD (1999) Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. J Neurosci 19:1179-1188.
    • (1999) J Neurosci , vol.19 , pp. 1179-1188
    • Singh, M.1    Sétáló G., Jr.2    Guan, X.3    Warren, M.4    Toran-Allerand, C.D.5
  • 39
    • 0028264440 scopus 로고
    • Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells
    • Sohrabji F, Greene LA, Miranda RC, Toran-Allerand CD (1994a) Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells. J Neurobiol 25:974-988.
    • (1994) J Neurobiol , vol.25 , pp. 974-988
    • Sohrabji, F.1    Greene, L.A.2    Miranda, R.C.3    Toran-Allerand, C.D.4
  • 40
    • 0028144602 scopus 로고
    • Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons
    • Sohrabji F, Miranda RC, Toran-Allerand CD (1994b) Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons. J Neurosci 14:459-471.
    • (1994) J Neurosci , vol.14 , pp. 459-471
    • Sohrabji, F.1    Miranda, R.C.2    Toran-Allerand, C.D.3
  • 42
    • 0030753755 scopus 로고    scopus 로고
    • Rapid membrane effects of steroids on neuroblastoma cells: Effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription
    • Watters JJ, Campbell JS, Cunningham MJ, Krebs EG, Dorsa DM (1997) Rapid membrane effects of steroids on neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology 138: 4030-4033.
    • (1997) Endocrinology , vol.138 , pp. 4030-4033
    • Watters, J.J.1    Campbell, J.S.2    Cunningham, M.J.3    Krebs, E.G.4    Dorsa, D.M.5
  • 43
    • 0029950722 scopus 로고    scopus 로고
    • A role of ral guanine nucleotide dissociation stimulator in mediating ras-induced transformation
    • White MA, Vale T, Camonis JH, Schaefer E, Wigler MH (1996) A role of ral guanine nucleotide dissociation stimulator in mediating ras-induced transformation. J Biol Chem 271:16439-16442.
    • (1996) J Biol Chem , vol.271 , pp. 16439-16442
    • White, M.A.1    Vale, T.2    Camonis, J.H.3    Schaefer, E.4    Wigler, M.H.5
  • 44
    • 0026668286 scopus 로고
    • Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons
    • Wong M, Moss RL (1992) Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons. J Neurosci 12:3217-3225.
    • (1992) J Neurosci , vol.12 , pp. 3217-3225
    • Wong, M.1    Moss, R.L.2
  • 45


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