메뉴 건너뛰기




Volumn 73, Issue 2, 1999, Pages 466-475

The survival of sympathetic neurons promoted by potassium depolarization, but not by cyclic AMP, requires phosphatidylinositol 3- kinase and Akt

Author keywords

Apoptosis; Cyclic AMP; Depolarization; Nerve growth factor; Phosphatidylinositol 3 kinase; Sympathetic neuron

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; CYCLIC AMP; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM; PROTEIN KINASE B;

EID: 0032788544     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0730466.x     Document Type: Article
Times cited : (50)

References (56)
  • 3
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji S. X., Majdan M., Pozniak C. D., Belliveau D. J., Aloyz R., Kohn J., Causing C. G., and Miller F. D. (1998) The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140, 911-923.
    • (1998) J. Cell Biol. , vol.140 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 5
    • 0028142584 scopus 로고
    • Expression of the cyclic AMP-dependent protein kinase (PKA) catalytic subunit from a herpes simplex virus vector extends the survival of rat sympathetic neurons in the absence of NGF
    • Buckmaster E. A. and Tolkovsky A. M. (1994) Expression of the cyclic AMP-dependent protein kinase (PKA) catalytic subunit from a herpes simplex virus vector extends the survival of rat sympathetic neurons in the absence of NGF. Eur. J. Neurosci. 6, 1316-1327.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1316-1327
    • Buckmaster, E.A.1    Tolkovsky, A.M.2
  • 7
    • 0026659868 scopus 로고
    • Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells
    • Carter A. N. and Downes C. P. (1992) Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells. J. Biol. Chem. 267, 14563-14567.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14563-14567
    • Carter, A.N.1    Downes, C.P.2
  • 8
    • 0029834669 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival
    • Creedon D. J., Johnson E. M., and Lawrence J. C. (1996) Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival. J. Biol. Chem. 271, 20713-20718.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20713-20718
    • Creedon, D.J.1    Johnson, E.M.2    Lawrence, J.C.3
  • 9
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross D. A., Alessi D. R., Cohen P., Andjelkovich M., and Hemmings B. A. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 10
    • 0032522924 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Atk protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons
    • Crowder R. J. and Freeman R. S. (1998) Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18, 2933-2943.
    • (1998) J. Neurosci. , vol.18 , pp. 2933-2943
    • Crowder, R.J.1    Freeman, R.S.2
  • 11
    • 0029807471 scopus 로고    scopus 로고
    • Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells
    • Datta K., Bellacosa A., Chan T. O., and Tsichlis P. N. (1996) Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells. J. Biol. Chem. 271, 30835-30839.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30835-30839
    • Datta, K.1    Bellacosa, A.2    Chan, T.O.3    Tsichlis, P.N.4
  • 12
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of bad couples survival signals to the cell-intrinsic death machinery
    • Datta S. R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., and Greenberg M. E. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91, 231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 13
    • 0027485950 scopus 로고
    • Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor (NGF)
    • Deckwerth T. L. and Johnson E. M. Jr. (1993) Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor (NGF). J. Cell Biol. 123, 1207-1222.
    • (1993) J. Cell Biol. , vol.123 , pp. 1207-1222
    • Deckwerth, T.L.1    Johnson E.M., Jr.2
  • 14
    • 0030458720 scopus 로고    scopus 로고
    • Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ice family proteases
    • Deshmukh M., Vasilakos J., Deckwerth T. L., Lampe P. A., Shivers B. D., and Johnson E. M. Jr. (1996) Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J. Cell Biol. 135, 1341-1354.
    • (1996) J. Cell Biol. , vol.135 , pp. 1341-1354
    • Deshmukh, M.1    Vasilakos, J.2    Deckwerth, T.L.3    Lampe, P.A.4    Shivers, B.D.5    Johnson E.M., Jr.6
  • 15
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor and cAMP
    • D'Mello S. R., Galli C., Ciotti T., and Calissano P. (1993) Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor and cAMP. Proc. Natl. Acad. Sci. USA 90, 10989-10993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 16
    • 0031054670 scopus 로고    scopus 로고
    • Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI 3-kinase in IGF-1 signaling
    • D'Mello S. R., Borodezt K., and Soltoff S. P. (1997) Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling. J. Neurosci. 17, 1548-1560.
    • (1997) J. Neurosci. , vol.17 , pp. 1548-1560
    • D'Mello, S.R.1    Borodezt, K.2    Soltoff, S.P.3
  • 18
    • 0028803687 scopus 로고
    • Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK
    • Earp H. S., Huckle W. R., Dawson T. L., Li X., Graves L. M., and Dy R. (1995) Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK. J. Biol. Chem. 270, 28440-28447.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28440-28447
    • Earp, H.S.1    Huckle, W.R.2    Dawson, T.L.3    Li, X.4    Graves, L.M.5    Dy, R.6
  • 19
    • 0025786538 scopus 로고
    • The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization
    • Edwards S. N., Buckmaster A. E., and Tolkovsky A. M. (1991) The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization. J. Neurochem. 57, 2140-2143.
    • (1991) J. Neurochem. , vol.57 , pp. 2140-2143
    • Edwards, S.N.1    Buckmaster, A.E.2    Tolkovsky, A.M.3
  • 20
    • 0032549659 scopus 로고    scopus 로고
    • High affinity calmodulin target sequence in the signaling molecule PI 3-kinase
    • Fischer R., Julsgart J., and Berchtold M. W. (1998) High affinity calmodulin target sequence in the signaling molecule PI 3-kinase. FEBS Lett. 425, 175-177.
    • (1998) FEBS Lett. , vol.425 , pp. 175-177
    • Fischer, R.1    Julsgart, J.2    Berchtold, M.W.3
  • 21
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
    • Franke T. F., Kaplan D. R., Cantley L. C., and Toker A. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275, 665-668.
    • (1997) Science , vol.275 , pp. 665-668
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3    Toker, A.4
  • 22
    • 0026482631 scopus 로고
    • Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium
    • Franklin J. L. and Johnson E. M. Jr. (1992) Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends Neurosci. 15, 501-508.
    • (1992) Trends Neurosci. , vol.15 , pp. 501-508
    • Franklin, J.L.1    Johnson E.M., Jr.2
  • 24
    • 0023244774 scopus 로고
    • The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
    • Gallo V., Kingsbury A., Balazs R., and Jorgensen O. S. (1987) The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J. Neurosci. 7, 2203-2213.
    • (1987) J. Neurosci. , vol.7 , pp. 2203-2213
    • Gallo, V.1    Kingsbury, A.2    Balazs, R.3    Jorgensen, O.S.4
  • 25
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., and Ben-Sasson S. A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 27
    • 0028918408 scopus 로고
    • Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
    • Hu Q., Klippel A., Muslin A. J., Fantl W. J., and Williams L. T. (1995) Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 268, 100-102.
    • (1995) Science , vol.268 , pp. 100-102
    • Hu, Q.1    Klippel, A.2    Muslin, A.J.3    Fantl, W.J.4    Williams, L.T.5
  • 33
    • 0031015986 scopus 로고    scopus 로고
    • A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain
    • Klippel A., Kavanaugh W. M., Pot D., and Williams L. T. (1997) A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol. Cell. Biol. 17, 338-344.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 338-344
    • Klippel, A.1    Kavanaugh, W.M.2    Pot, D.3    Williams, L.T.4
  • 34
    • 0029810181 scopus 로고    scopus 로고
    • Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
    • Kohn A. D., Takeuchi F., and Roth R. A. (1996) Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J. Biol. Chem. 271, 21920-21926.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21920-21926
    • Kohn, A.D.1    Takeuchi, F.2    Roth, R.A.3
  • 36
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G., Klippel A., and Weber M. J. (1997) Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17, 1595-1606.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 38
    • 0023851503 scopus 로고
    • Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
    • Martin D. P., Schmidt R. E., DiStefano P. S., Lowry O. H., Carter J. G., and Johnson E. M. Jr. (1988) Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol. 106, 829-844.
    • (1988) J. Cell Biol. , vol.106 , pp. 829-844
    • Martin, D.P.1    Schmidt, R.E.2    DiStefano, P.S.3    Lowry, O.H.4    Carter, J.G.5    Johnson E.M., Jr.6
  • 39
    • 0030938816 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor 1-mediated survival of cerebellar granule cells
    • Miller T. M., Tansey M. G., Johnson E. M., and Creedon D. J. (1997) Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor 1-mediated survival of cerebellar granule cells. J. Biol. Chem. 272, 9847-9853.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9847-9853
    • Miller, T.M.1    Tansey, M.G.2    Johnson, E.M.3    Creedon, D.J.4
  • 40
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway
    • Pap M. and Cooper G. M. (1998) Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. 273, 19929-19932.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 41
    • 0030694175 scopus 로고    scopus 로고
    • Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
    • Philpott K. L., McCarthy M. J., Klippel A., and Rubin L. L. (1997) Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J. Cell Biol. 139, 809-815.
    • (1997) J. Cell Biol. , vol.139 , pp. 809-815
    • Philpott, K.L.1    McCarthy, M.J.2    Klippel, A.3    Rubin, L.L.4
  • 42
    • 0026666371 scopus 로고
    • Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells
    • Raffioni S. and Bradshaw R. A. (1992) Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells. Proc. Natl. Acad. Sci. USA 89, 9121-9125.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9121-9125
    • Raffioni, S.1    Bradshaw, R.A.2
  • 44
    • 0030032998 scopus 로고    scopus 로고
    • Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels
    • Rosen L. B. and Greenberg M. E. (1996) Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc. Natl. Acad. Sci. USA 93, 1113-1118.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1113-1118
    • Rosen, L.B.A.1    Greenberg, M.E.2
  • 45
    • 0028277844 scopus 로고
    • Membrane depolarization and calcium influx stimulate mek and MAP kinase via activation of Ras
    • Rosen L. B., Ginty D. D., Weber M. J., and Greenberg M. E. (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12, 1207-1221.
    • (1994) Neuron , vol.12 , pp. 1207-1221
    • Rosen, L.B.1    Ginty, D.D.2    Weber, M.J.3    Greenberg, M.E.4
  • 46
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
    • Rukenstein A., Rydel R. E., and Greene L. A. (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J. Neurosci. 11, 2552-2563.
    • (1991) J. Neurosci. , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 47
    • 0029616354 scopus 로고
    • Calcium influx induces neurite growth through a Src-Ras signaling cassette
    • Rusanescu G., Qi H., Thomas S. M., Brugge J. S., and Halegoua S. (1995) Calcium influx induces neurite growth through a Src-Ras signaling cassette. Neuron 15, 1415-1425.
    • (1995) Neuron , vol.15 , pp. 1415-1425
    • Rusanescu, G.1    Qi, H.2    Thomas, S.M.3    Brugge, J.S.4    Halegoua, S.5
  • 48
    • 0001477595 scopus 로고
    • cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
    • Rydel R. E. and Greene L. A. (1988) cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor. Proc. Natl. Acad. Sci. USA 85, 1257-1261.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1257-1261
    • Rydel, R.E.1    Greene, L.A.2
  • 49
    • 0032519650 scopus 로고    scopus 로고
    • Calmodulin is involved in membrane depolarization-mediated survival of motoneurons by phosphatidylinositol-3 kinase- and MAPK-independent pathways
    • Soler R. M., Egea J., Mintenig G. M., Sanz-Rodriguez C., Iglesias M., and Comelia J. X. (1998) Calmodulin is involved in membrane depolarization-mediated survival of motoneurons by phosphatidylinositol-3 kinase- and MAPK-independent pathways. J. Neurosci. 18, 1230-1239.
    • (1998) J. Neurosci. , vol.18 , pp. 1230-1239
    • Soler, R.M.1    Egea, J.2    Mintenig, G.M.3    Sanz-Rodriguez, C.4    Iglesias, M.5    Comelia, J.X.6
  • 50
    • 0026802515 scopus 로고
    • Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase
    • Soltoff S. P., Rabin S. L., Cantley L. C., and Kaplan D. R. (1992) Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase. J. Biol. Chem. 267, 17472-17477.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17472-17477
    • Soltoff, S.P.1    Rabin, S.L.2    Cantley, L.C.3    Kaplan, D.R.4
  • 52
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos C. J., Matter W. F., Hui K. Y., and Brown R. F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 53
    • 0030777767 scopus 로고    scopus 로고
    • Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase
    • Xiong W. and Parsons J. T. (1997) Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase. J. Cell Biol. 139, 529-539.
    • (1997) J. Cell Biol. , vol.139 , pp. 529-539
    • Xiong, W.1    Parsons, J.T.2
  • 54
    • 0032506514 scopus 로고    scopus 로고
    • Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
    • Yano S., Tokumitsu H., and Soderling T. R. (1998) Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature 396, 584-587.
    • (1998) Nature , vol.396 , pp. 584-587
    • Yano, S.1    Tokumitsu, H.2    Soderling, T.R.3
  • 55
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao R. and Cooper G. M. (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267, 2003-2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 56
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J., Harada H., Yang E., Jockel J., and Korsmeyer S. J. (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 87, 619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.