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Volumn 253, Issue 1, 1999, Pages 131-142

Neurotrophin signaling via Trks and p75

Author keywords

Neurons; Neurotrophins; P75; Signaling; Trks

Indexed keywords

ADAPTOR PROTEIN; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4; NEUROTROPHIN RECEPTOR; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

EID: 0033604518     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4705     Document Type: Article
Times cited : (318)

References (145)
  • 1
    • 0028808732 scopus 로고
    • Early events in neurotrophin signaling via Trk and p75 receptors
    • Greene L. A., Kaplan D. R. Early events in neurotrophin signaling via Trk and p75 receptors. Curr. Opin. Neurobiol. 5:1995;579-587.
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 579-587
    • Greene, L.A.1    Kaplan, D.R.2
  • 2
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal R. A., Greenberg M. E. Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19:1996;463-489.
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 4
    • 0032006901 scopus 로고    scopus 로고
    • Nerve growth factor: Two receptors, multiple functions
    • Frade J. M., Barde Y. A. Nerve growth factor: Two receptors, multiple functions. Bioessays. 20:1998;137-145.
    • (1998) Bioessays , vol.20 , pp. 137-145
    • Frade, J.M.1    Barde, Y.A.2
  • 5
    • 0030907924 scopus 로고    scopus 로고
    • Signal transduction by the neurotrophin receptors
    • Kaplan D. R., Miller F. D. Signal transduction by the neurotrophin receptors. Curr. Opin. Cell. Biol. 9:1997;213-221.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 213-221
    • Kaplan, D.R.1    Miller, F.D.2
  • 6
    • 0031772820 scopus 로고    scopus 로고
    • Studying signal transduction in neuronal cells: The Trk/NGF system
    • Kaplan D. R. Studying signal transduction in neuronal cells: The Trk/NGF system. Prog. Brain Res. 117:1998;35-46.
    • (1998) Prog. Brain Res. , vol.117 , pp. 35-46
    • Kaplan, D.R.1
  • 7
    • 0033563189 scopus 로고    scopus 로고
    • Trks: Signal transduction and intracellular pathways
    • Klesse L. J., Parada L. F. Trks: Signal transduction and intracellular pathways. Microsc. Res. Tech. 45:1999;210-216.
    • (1999) Microsc. Res. Tech. , vol.45 , pp. 210-216
    • Klesse, L.J.1    Parada, L.F.2
  • 8
    • 0032538877 scopus 로고    scopus 로고
    • The saga of the nerve growth factor
    • Levi-Montalcini R. The saga of the nerve growth factor. Neuroreport. 9:1998;R71-R83.
    • (1998) Neuroreport , vol.9
    • Levi-Montalcini, R.1
  • 9
    • 0033004063 scopus 로고    scopus 로고
    • Neurotrophin regulation of synaptic transmission
    • Schuman E. M. Neurotrophin regulation of synaptic transmission. Curr. Opin. Neurobiol. 9:1999;105-109.
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 105-109
    • Schuman, E.M.1
  • 10
    • 0030759543 scopus 로고    scopus 로고
    • Neurotrophin regulation of the developing nervous system: Analyses of knockout mice
    • Conover J. C., Yancopoulos G. D. Neurotrophin regulation of the developing nervous system: Analyses of knockout mice. Rev. Neurosci. 8:1997;13-27.
    • (1997) Rev. Neurosci. , vol.8 , pp. 13-27
    • Conover, J.C.1    Yancopoulos, G.D.2
  • 11
    • 0030767944 scopus 로고    scopus 로고
    • Role of neurotrophins in synapse development and plasticity
    • Lu B., Figurov A. Role of neurotrophins in synapse development and plasticity. Rev. Neurosci. 8:1997;1-12.
    • (1997) Rev. Neurosci. , vol.8 , pp. 1-12
    • Lu, B.1    Figurov, A.2
  • 12
    • 0030078595 scopus 로고    scopus 로고
    • Neurotrophin-3 as an essential signal for the developing nervous system
    • Chalazonitis A. Neurotrophin-3 as an essential signal for the developing nervous system. Mol. Neurobiol. 12:1996;39-53.
    • (1996) Mol. Neurobiol. , vol.12 , pp. 39-53
    • Chalazonitis, A.1
  • 13
  • 15
    • 0029556562 scopus 로고
    • Structural and functional properties of the TRK family of neurotrophin receptors
    • Barbacid M. Structural and functional properties of the TRK family of neurotrophin receptors. Ann. N.Y. Acad. Sci. 766:1995;442-458.
    • (1995) Ann. N.Y. Acad. Sci. , vol.766 , pp. 442-458
    • Barbacid, M.1
  • 16
    • 0028358877 scopus 로고
    • Neurotrophic factors and their receptors
    • Ip N. Y., Yancopoulos G. D. Neurotrophic factors and their receptors. Ann. Neurol. 35:1994;S13-S16.
    • (1994) Ann. Neurol. , vol.35
    • Ip, N.Y.1    Yancopoulos, G.D.2
  • 18
    • 0025735392 scopus 로고
    • The trk proto-oncogene product: A signal transducing receptor for nerve growth factor [see comments]
    • Kaplan D. R., Hempstead B. L., Martin-Zanca D., Chao M. V., Parada L. F. The trk proto-oncogene product: A signal transducing receptor for nerve growth factor [see comments]. Science. 252:1991;554-558.
    • (1991) Science , vol.252 , pp. 554-558
    • Kaplan, D.R.1    Hempstead, B.L.2    Martin-Zanca, D.3    Chao, M.V.4    Parada, L.F.5
  • 19
    • 0025857391 scopus 로고
    • The trk proto-oncogene encodes a receptor for nerve growth factor
    • Klein R., Jing S. Q., Nanduri V., O'Rourke E., Barbacid M. The trk proto-oncogene encodes a receptor for nerve growth factor. Cell. 65:1991;189-197.
    • (1991) Cell , vol.65 , pp. 189-197
    • Klein, R.1    Jing, S.Q.2    Nanduri, V.3    O'Rourke, E.4    Barbacid, M.5
  • 20
    • 0026091934 scopus 로고
    • The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines
    • Loeb D. M., Maragos J., Martin-Zanca D., Chao M. V., Parada L. F., Greene L. A. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell. 66:1991;961-966.
    • (1991) Cell , vol.66 , pp. 961-966
    • Loeb, D.M.1    Maragos, J.2    Martin-Zanca, D.3    Chao, M.V.4    Parada, L.F.5    Greene, L.A.6
  • 21
    • 0027263736 scopus 로고
    • Transfection with trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants
    • Loeb D. M., Greene L. A. Transfection with trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants. J. Neurosci. 13:1993;2919-2929.
    • (1993) J. Neurosci. , vol.13 , pp. 2919-2929
    • Loeb, D.M.1    Greene, L.A.2
  • 22
    • 0031007865 scopus 로고    scopus 로고
    • Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos
    • Wyatt S., Pinon L. G., Ernfors P., Davies A. M. Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos. EMBO J. 16:1997;3115-3123.
    • (1997) EMBO J. , vol.16 , pp. 3115-3123
    • Wyatt, S.1    Pinon, L.G.2    Ernfors, P.3    Davies, A.M.4
  • 23
    • 0026025820 scopus 로고
    • TrkB, a neural receptor protein-tyrosine kinase: Evidence for a full-length and two truncated receptors
    • Middlemas D. S., Lindberg R. A., Hunter T. trkB, a neural receptor protein-tyrosine kinase: Evidence for a full-length and two truncated receptors. Mol. Cell. Biol. 11:1991;143-153.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 143-153
    • Middlemas, D.S.1    Lindberg, R.A.2    Hunter, T.3
  • 25
    • 0033565944 scopus 로고    scopus 로고
    • Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells
    • Kryl D., Yacoubian T., Haapasalo A., Castren E., Lo D., Barker P. A. Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. J. Neurosci. 19:1999;5823-5833.
    • (1999) J. Neurosci. , vol.19 , pp. 5823-5833
    • Kryl, D.1    Yacoubian, T.2    Haapasalo, A.3    Castren, E.4    Lo, D.5    Barker, P.A.6
  • 26
    • 0028846967 scopus 로고
    • Nerve growth factor binding site on TrkA mapped to a single 24-amino acid leucine-rich motif
    • Windisch J. M., Marksteiner R., Schneider R. Nerve growth factor binding site on TrkA mapped to a single 24-amino acid leucine-rich motif. J. Biol. Chem. 270:1995;28133-28138.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28133-28138
    • Windisch, J.M.1    Marksteiner, R.2    Schneider, R.3
  • 28
    • 0032489439 scopus 로고    scopus 로고
    • High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors
    • Urfer R., Tsoulfas P., O'Connell L., Hongo J. A., Zhao W., Presta L. G. High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors. J. Biol. Chem. 273:1998;5829-5840.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5829-5840
    • Urfer, R.1    Tsoulfas, P.2    O'Connell, L.3    Hongo, J.A.4    Zhao, W.5    Presta, L.G.6
  • 30
    • 0027050178 scopus 로고
    • Nerve growth factor mediates signal transduction through trk homodimer receptors
    • Jing S., Tapley P., Barbacid M. Nerve growth factor mediates signal transduction through trk homodimer receptors. Neuron. 9:1992;1067-1079.
    • (1992) Neuron , vol.9 , pp. 1067-1079
    • Jing, S.1    Tapley, P.2    Barbacid, M.3
  • 31
    • 0026468503 scopus 로고
    • Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation
    • Hempstead B. L., Rabin S. J., Kaplan L., Reid S., Parada L. F., Kaplan D. R. Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron. 9:1992;883-896.
    • (1992) Neuron , vol.9 , pp. 883-896
    • Hempstead, B.L.1    Rabin, S.J.2    Kaplan, L.3    Reid, S.4    Parada, L.F.5    Kaplan, D.R.6
  • 32
    • 0028873047 scopus 로고
    • Prevention of apoptotic neuronal death by GM1 ganglioside. Involvement of Trk neurotrophin receptors
    • Ferrari G., Anderson B. L., Stephens R. M., Kaplan D. R., Greene L. A. Prevention of apoptotic neuronal death by GM1 ganglioside. Involvement of Trk neurotrophin receptors. J. Biol. Chem. 270:1995;3074-3080.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3074-3080
    • Ferrari, G.1    Anderson, B.L.2    Stephens, R.M.3    Kaplan, D.R.4    Greene, L.A.5
  • 34
    • 0032998629 scopus 로고    scopus 로고
    • Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation
    • MacPhee I., Barker P. A. Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation. J. Neurochem. 72:1999;1423-1430.
    • (1999) J. Neurochem. , vol.72 , pp. 1423-1430
    • MacPhee, I.1    Barker, P.A.2
  • 35
    • 0031880893 scopus 로고    scopus 로고
    • Promotion of neuronal survival by GM1 ganglioside. Phenomenology and mechanism of action
    • Ferrari G., Greene L. A. Promotion of neuronal survival by GM1 ganglioside. Phenomenology and mechanism of action. Ann. N.Y. Acad. Sci. 845:1998;263-273.
    • (1998) Ann. N.Y. Acad. Sci. , vol.845 , pp. 263-273
    • Ferrari, G.1    Greene, L.A.2
  • 36
    • 0032475936 scopus 로고    scopus 로고
    • Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells
    • Mutoh T., Tokuda A., Inokuchi J., Kuriyama M. Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells. J. Biol. Chem. 273:1998;26001-26007.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26001-26007
    • Mutoh, T.1    Tokuda, A.2    Inokuchi, J.3    Kuriyama, M.4
  • 37
    • 0030991784 scopus 로고    scopus 로고
    • Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor
    • Cunningham M. E., Stephens R. M., Kaplan D. R., Greene L. A. Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor. J. Biol. Chem. 272:1997;10957-10967.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10957-10967
    • Cunningham, M.E.1    Stephens, R.M.2    Kaplan, D.R.3    Greene, L.A.4
  • 38
    • 0032535448 scopus 로고    scopus 로고
    • A function-structure model for NGF-activated TRK
    • Cunningham M. E., Greene L. A. A function-structure model for NGF-activated TRK. EMBO J. 17:1998;7282-7293.
    • (1998) EMBO J. , vol.17 , pp. 7282-7293
    • Cunningham, M.E.1    Greene, L.A.2
  • 39
    • 0028245830 scopus 로고
    • A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth
    • Loeb D. M., Stephens R. M., Copeland T., Kaplan D. R., Greene L. A. A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth. J. Biol. Chem. 269:1994;8901-8910.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8901-8910
    • Loeb, D.M.1    Stephens, R.M.2    Copeland, T.3    Kaplan, D.R.4    Greene, L.A.5
  • 40
    • 0028199799 scopus 로고
    • Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses
    • Stephens R. M., Loeb D. M., Copeland T. D., Pawson T., Greene L. A., Kaplan D. R. Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron. 12:1994;691-705.
    • (1994) Neuron , vol.12 , pp. 691-705
    • Stephens, R.M.1    Loeb, D.M.2    Copeland, T.D.3    Pawson, T.4    Greene, L.A.5    Kaplan, D.R.6
  • 41
    • 0028293929 scopus 로고
    • Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma
    • Obermeier A., Bradshaw R. A., Seedorf K., Choidas A., Schlessinger J., Ullrich A. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J. 13:1994;1585-1590.
    • (1994) EMBO J. , vol.13 , pp. 1585-1590
    • Obermeier, A.1    Bradshaw, R.A.2    Seedorf, K.3    Choidas, A.4    Schlessinger, J.5    Ullrich, A.6
  • 42
    • 0033591229 scopus 로고    scopus 로고
    • The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells
    • Yamashita H., Avraham S., Jiang S., Dikic I., Avraham H. The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells. J. Biol. Chem. 274:1999;15059-15065.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15059-15065
    • Yamashita, H.1    Avraham, S.2    Jiang, S.3    Dikic, I.4    Avraham, H.5
  • 43
    • 0027996869 scopus 로고
    • Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor
    • Basu T., Warne P. H., Downward J. Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor. Oncogene. 9:1994;3483-3491.
    • (1994) Oncogene , vol.9 , pp. 3483-3491
    • Basu, T.1    Warne, P.H.2    Downward, J.3
  • 45
    • 0031842341 scopus 로고    scopus 로고
    • Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
    • Ganju P., O'Bryan J. P., Der C., Winter J., James I. F. Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells. Eur. J. Neurosci. 10:1998;1995-2008.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1995-2008
    • Ganju, P.1    O'Bryan, J.P.2    Der, C.3    Winter, J.4    James, I.F.5
  • 46
    • 0032549675 scopus 로고    scopus 로고
    • N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling
    • Nakamura T., Muraoka S., Sanokawa R., Mori N. N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling. J. Biol. Chem. 273:1998;6960-6967.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6960-6967
    • Nakamura, T.1    Muraoka, S.2    Sanokawa, R.3    Mori, N.4
  • 47
    • 0027374486 scopus 로고
    • Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex
    • Obermeier A., Lammers R., Wiesmuller K. H., Jung G., Schlessinger J., Ullrich A. Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex. J. Biol. Chem. 268:1993;22963-22966.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22963-22966
    • Obermeier, A.1    Lammers, R.2    Wiesmuller, K.H.3    Jung, G.4    Schlessinger, J.5    Ullrich, A.6
  • 48
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
    • Kouhara H., Hadari Y. R., Spivak-Kroizman T., Schilling J., Bar-Sagi D., Lax I., Schlessinger J. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell. 89:1997;693-702.
    • (1997) Cell , vol.89 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.R.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 49
    • 0033574538 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces phosphorylation of fibroblast growth factor receptor substrate 2
    • Easton J. B., Moody N. M., Zhu X., Middlemas D. S. Brain-derived neurotrophic factor induces phosphorylation of fibroblast growth factor receptor substrate 2. J. Biol. Chem. 274:1999;11321-11327.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11321-11327
    • Easton, J.B.1    Moody, N.M.2    Zhu, X.3    Middlemas, D.S.4
  • 50
    • 0033515534 scopus 로고    scopus 로고
    • The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation
    • Meakin S. O., MacDonald J. I., Gryz E. A., Kubu C. J., Verdi J. M. The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation. J. Biol. Chem. 274:1999;9861-9870.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9861-9870
    • Meakin, S.O.1    MacDonald, J.I.2    Gryz, E.A.3    Kubu, C.J.4    Verdi, J.M.5
  • 51
    • 0031835659 scopus 로고    scopus 로고
    • Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation
    • Hadari Y. R., Kouhara H., Lax I., Schlessinger J. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. Mol. Cell. Biol. 18:1998;3966-3973.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3966-3973
    • Hadari, Y.R.1    Kouhara, H.2    Lax, I.3    Schlessinger, J.4
  • 52
    • 0032540941 scopus 로고    scopus 로고
    • Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
    • Xu H., Lee K. W., Goldfarb M. Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. J. Biol. Chem. 273:1998;17987-17990.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17987-17990
    • Xu, H.1    Lee, K.W.2    Goldfarb, M.3
  • 53
    • 0027395119 scopus 로고
    • SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells
    • Rabin S. J., Cleghon V., Kaplan D. R. SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol. Cell. Biol. 13:1993;2203-2213.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2203-2213
    • Rabin, S.J.1    Cleghon, V.2    Kaplan, D.R.3
  • 54
    • 0029082202 scopus 로고
    • Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis
    • Peng X., Greene L. A., Kaplan D. R., Stephens R. M. Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis. Neuron. 15:1995;395-406.
    • (1995) Neuron , vol.15 , pp. 395-406
    • Peng, X.1    Greene, L.A.2    Kaplan, D.R.3    Stephens, R.M.4
  • 55
    • 0032418850 scopus 로고    scopus 로고
    • Identification and characterization of novel substrates of Trk receptors in developing neurons
    • Qian X., Riccio A., Zhang Y., Ginty D. D. Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron. 21:1998;1017-1029.
    • (1998) Neuron , vol.21 , pp. 1017-1029
    • Qian, X.1    Riccio, A.2    Zhang, Y.3    Ginty, D.D.4
  • 56
    • 0030856143 scopus 로고    scopus 로고
    • Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons
    • Yamada M., Ohnishi H., Sano S., Nakatani A., Ikeuchi T., Hatanaka H. Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons. J. Biol. Chem. 272:1997;30334-30339.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30334-30339
    • Yamada, M.1    Ohnishi, H.2    Sano, S.3    Nakatani, A.4    Ikeuchi, T.5    Hatanaka, H.6
  • 57
    • 0030812590 scopus 로고    scopus 로고
    • Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor
    • Holgado-Madruga M., Moscatello D. K., Emlet D. R., Dieterich R., Wong A. J. Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor. Proc. Natl. Acad. Sci. USA. 94:1997;12419-12424.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12419-12424
    • Holgado-Madruga, M.1    Moscatello, D.K.2    Emlet, D.R.3    Dieterich, R.4    Wong, A.J.5
  • 58
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke T. F., Kaplan D. R., Cantley L. C. PI3K: Downstream AKTion blocks apoptosis. Cell. 88:1997;435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 59
    • 0030053945 scopus 로고    scopus 로고
    • Nerve growth factor induces a multimeric TrkA receptor complex in neuronal cells that includes Crk, SHC and PLC-gamma 1 but excludes P130CAS
    • Torres M., Bogenmann E. Nerve growth factor induces a multimeric TrkA receptor complex in neuronal cells that includes Crk, SHC and PLC-gamma 1 but excludes P130CAS. Oncogene. 12:1996;77-86.
    • (1996) Oncogene , vol.12 , pp. 77-86
    • Torres, M.1    Bogenmann, E.2
  • 60
    • 0029871329 scopus 로고    scopus 로고
    • Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells
    • Ribon V., Saltiel A. R. Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells. J. Biol. Chem. 271:1996;7375-7380.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7375-7380
    • Ribon, V.1    Saltiel, A.R.2
  • 61
    • 0028122971 scopus 로고
    • CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells
    • Matsuda M., Hashimoto Y., Muroya K., Hasegawa H., Kurata T., Tanaka S., Nakamura S., Hattori S. CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells. Mol. Cell. Biol. 14:1994;5495-5500.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5495-5500
    • Matsuda, M.1    Hashimoto, Y.2    Muroya, K.3    Hasegawa, H.4    Kurata, T.5    Tanaka, S.6    Nakamura, S.7    Hattori, S.8
  • 62
    • 0032499282 scopus 로고    scopus 로고
    • Rap1 mediates sustained MAP kinase activation induced by nerve growth factor [see comments]
    • York R. D., Yao H., Dillon T., Ellig C. L., Eckert S. P., McCleskey E. W., Stork P. J. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor [see comments]. Nature. 392:1998;622-626.
    • (1998) Nature , vol.392 , pp. 622-626
    • York, R.D.1    Yao, H.2    Dillon, T.3    Ellig, C.L.4    Eckert, S.P.5    McCleskey, E.W.6    Stork, P.J.7
  • 63
    • 0030221509 scopus 로고    scopus 로고
    • Dissociation of NGF induced signal transduction from neurite elongation by expression of a mutant adaptor protein v-Crk in PC12 cells
    • Teng K. K., Courtney J. C., Henegouwen P. B., Birge R. B., Hempstead B. L. Dissociation of NGF induced signal transduction from neurite elongation by expression of a mutant adaptor protein v-Crk in PC12 cells. Mol. Cell. Neurosci. 8:1996;157-170.
    • (1996) Mol. Cell. Neurosci. , vol.8 , pp. 157-170
    • Teng, K.K.1    Courtney, J.C.2    Henegouwen, P.B.3    Birge, R.B.4    Hempstead, B.L.5
  • 64
    • 0030756918 scopus 로고    scopus 로고
    • Transient association of the phosphotyrosine phosphatase SHP-2 with TrkA is induced by nerve growth factor
    • Goldsmith B. A., Koizumi S. Transient association of the phosphotyrosine phosphatase SHP-2 with TrkA is induced by nerve growth factor. J. Neurochem. 69:1997;1014-1019.
    • (1997) J. Neurochem. , vol.69 , pp. 1014-1019
    • Goldsmith, B.A.1    Koizumi, S.2
  • 65
    • 0033066759 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and association of BIT with SHP-2 induced by neurotrophins
    • Ohnishi H., Yamada M., Kubota M., Hatanaka H., Sano S. Tyrosine phosphorylation and association of BIT with SHP-2 induced by neurotrophins. J. Neurochem. 72:1999;1402-1408.
    • (1999) J. Neurochem. , vol.72 , pp. 1402-1408
    • Ohnishi, H.1    Yamada, M.2    Kubota, M.3    Hatanaka, H.4    Sano, S.5
  • 67
    • 0033062990 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neurons
    • Yamada M., Ohnishi H., Sano S., Araki T., Nakatani A., Ikeuchi T., Hatanaka H. Brain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neurons. J. Neurochem. 73:1999;41-49.
    • (1999) J. Neurochem. , vol.73 , pp. 41-49
    • Yamada, M.1    Ohnishi, H.2    Sano, S.3    Araki, T.4    Nakatani, A.5    Ikeuchi, T.6    Hatanaka, H.7
  • 68
    • 0030929989 scopus 로고    scopus 로고
    • A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation
    • Wright J. H., Drueckes P., Bartoe J., Zhao Z., Shen S. H., Krebs E. G. A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation. Mol. Biol. Cell. 8:1997;1575-1585.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 1575-1585
    • Wright, J.H.1    Drueckes, P.2    Bartoe, J.3    Zhao, Z.4    Shen, S.H.5    Krebs, E.G.6
  • 69
    • 0032566002 scopus 로고    scopus 로고
    • Stimulation of the protein tyrosine kinase c-Yes but not c-Src by neurotrophins in human brain-metastatic melanoma cells
    • Marchetti D., Parikh N., Sudol M., Gallick G. E. Stimulation of the protein tyrosine kinase c-Yes but not c-Src by neurotrophins in human brain-metastatic melanoma cells. Oncogene. 16:1998;3253-3260.
    • (1998) Oncogene , vol.16 , pp. 3253-3260
    • Marchetti, D.1    Parikh, N.2    Sudol, M.3    Gallick, G.E.4
  • 71
    • 2642599031 scopus 로고    scopus 로고
    • Association of the Src family tyrosine kinase Fyn with TrkB
    • Iwasaki Y., Gay B., Wada K., Koizumi S. Association of the Src family tyrosine kinase Fyn with TrkB. J. Neurochem. 71:1998;106-111.
    • (1998) J. Neurochem. , vol.71 , pp. 106-111
    • Iwasaki, Y.1    Gay, B.2    Wada, K.3    Koizumi, S.4
  • 72
    • 0025931499 scopus 로고
    • Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions
    • Kremer N. E., D'Arcangelo G., Thomas S. M., DeMarco M., Brugge J. S., Halegoua S. Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions. J. Cell Biol. 115:1991;809-819.
    • (1991) J. Cell Biol. , vol.115 , pp. 809-819
    • Kremer, N.E.1    D'Arcangelo, G.2    Thomas, S.M.3    Demarco, M.4    Brugge, J.S.5    Halegoua, S.6
  • 73
    • 0032522924 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons
    • Crowder R. J., Freeman R. S. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18:1998;2933-2943.
    • (1998) J. Neurosci. , vol.18 , pp. 2933-2943
    • Crowder, R.J.1    Freeman, R.S.2
  • 74
    • 0031029870 scopus 로고    scopus 로고
    • Induction of a distinct morphology and signal transduction in TrkB/PC12 cells by nerve growth factor and brain-derived neurotrophic factor
    • Iwasaki Y., Ishikawa M., Okada N., Koizumi S. Induction of a distinct morphology and signal transduction in TrkB/PC12 cells by nerve growth factor and brain-derived neurotrophic factor. J. Neurochem. 68:1997;927-934.
    • (1997) J. Neurochem. , vol.68 , pp. 927-934
    • Iwasaki, Y.1    Ishikawa, M.2    Okada, N.3    Koizumi, S.4
  • 75
    • 0030920912 scopus 로고    scopus 로고
    • Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth
    • McAllister A. K., Katz L. C., Lo D. C. Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron. 18:1997;767-778.
    • (1997) Neuron , vol.18 , pp. 767-778
    • McAllister, A.K.1    Katz, L.C.2    Lo, D.C.3
  • 76
    • 0031409097 scopus 로고    scopus 로고
    • Activation of trk-A but not trk-B signal transduction pathway inhibits growth of neuroblastoma cells
    • Lucarelli E., Kaplan D., Thiele C. J. Activation of trk-A but not trk-B signal transduction pathway inhibits growth of neuroblastoma cells. Eur. J. Cancer. 33:1997;2068-2070.
    • (1997) Eur. J. Cancer , vol.33 , pp. 2068-2070
    • Lucarelli, E.1    Kaplan, D.2    Thiele, C.J.3
  • 77
    • 0030862873 scopus 로고    scopus 로고
    • Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor
    • Indo Y., Mardy S., Tsuruta M., Karim M. A., Matsuda I. Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor. Jpn. J. Hum. Genet. 42:1997;343-351.
    • (1997) Jpn. J. Hum. Genet. , vol.42 , pp. 343-351
    • Indo, Y.1    Mardy, S.2    Tsuruta, M.3    Karim, M.A.4    Matsuda, I.5
  • 79
    • 0032904490 scopus 로고    scopus 로고
    • Distribution and retrograde transport of trophic factors in the central nervous system: Functional implications for the treatment of neurodegenerative diseases
    • Mufson E. J., Kroin J. S., Sendera T. J., Sobreviela T. Distribution and retrograde transport of trophic factors in the central nervous system: Functional implications for the treatment of neurodegenerative diseases. Prog. Neurobiol. 57:1999;451-484.
    • (1999) Prog. Neurobiol. , vol.57 , pp. 451-484
    • Mufson, E.J.1    Kroin, J.S.2    Sendera, T.J.3    Sobreviela, T.4
  • 80
    • 0031788475 scopus 로고    scopus 로고
    • Retrograde axonal transport of neurotrophins: Differences between neuronal populations and implications for motor neuron disease
    • Bartlett S. E., Reynolds A. J., Hendry I. A. Retrograde axonal transport of neurotrophins: Differences between neuronal populations and implications for motor neuron disease. Immunol. Cell Biol. 76:1998;419-423.
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 419-423
    • Bartlett, S.E.1    Reynolds, A.J.2    Hendry, I.A.3
  • 85
    • 0030985451 scopus 로고    scopus 로고
    • A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA
    • Grimes M. L., Beattie E., Mobley W. C. A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA. Proc. Natl. Acad. Sci. USA. 94:1997;9909-9914.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9909-9914
    • Grimes, M.L.1    Beattie, E.2    Mobley, W.C.3
  • 86
    • 0031730287 scopus 로고    scopus 로고
    • Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis
    • Zapf-Colby A., Olefsky J. M. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology. 139:1998;3232-3240.
    • (1998) Endocrinology , vol.139 , pp. 3232-3240
    • Zapf-Colby, A.1    Olefsky, J.M.2
  • 87
    • 0030801304 scopus 로고    scopus 로고
    • An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons [see comments]
    • Riccio A., Pierchala B. A., Ciarallo C. L., Ginty D. D. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons [see comments]. Science. 277:1997;1097-1100.
    • (1997) Science , vol.277 , pp. 1097-1100
    • Riccio, A.1    Pierchala, B.A.2    Ciarallo, C.L.3    Ginty, D.D.4
  • 88
    • 0030861966 scopus 로고    scopus 로고
    • Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures
    • Senger D. L., Campenot R. B. Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J. Cell Biol. 138:1997;411-421.
    • (1997) J. Cell Biol. , vol.138 , pp. 411-421
    • Senger, D.L.1    Campenot, R.B.2
  • 89
    • 0025321521 scopus 로고
    • Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
    • Rodriguez-Tébar A., Dechant G., Barde Y.-A. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron. 4:1990;487-492.
    • (1990) Neuron , vol.4 , pp. 487-492
    • Rodriguez-Tébar, A.1    Dechant, G.2    Barde, Y.-A.3
  • 90
    • 0026608541 scopus 로고
    • Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor
    • Rodriguez-Tébar A., Dechant G., Gotz R., Barde Y. A. Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor. EMBO J. 11:1992;917-922.
    • (1992) EMBO J. , vol.11 , pp. 917-922
    • Rodriguez-Tébar, A.1    Dechant, G.2    Gotz, R.3    Barde, Y.A.4
  • 91
    • 0027942459 scopus 로고
    • The p75 neurotrophin receptor
    • Chao M. V. The p75 neurotrophin receptor. J. Neurobiol. 25:1994;1373-1385.
    • (1994) J. Neurobiol. , vol.25 , pp. 1373-1385
    • Chao, M.V.1
  • 92
    • 0025990724 scopus 로고
    • Disruption of cysteine rich repeats of the NGF receptor leads to loss of ligand binding
    • Yan H., Chao M. V. Disruption of cysteine rich repeats of the NGF receptor leads to loss of ligand binding. J. Biol. Chem. 266:1991;12099-12104.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12099-12104
    • Yan, H.1    Chao, M.V.2
  • 93
    • 0030851905 scopus 로고    scopus 로고
    • NMR structure of the death domain of the p75 neurotrophin receptor
    • Liepinsh E., Ilag L. L., Otting G., Ibáñez C. F. NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J. 16:1997;4999-5005.
    • (1997) EMBO J. , vol.16 , pp. 4999-5005
    • Liepinsh, E.1    Ilag, L.L.2    Otting, G.3    Ibáñez, C.F.4
  • 94
    • 0018584222 scopus 로고
    • Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglion cells
    • Sutter A., Riopelle R. J., Harris-Warrick R. M., Shooter E. M. Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglion cells. J. Biol. Chem. 254:1979;5972-5982.
    • (1979) J. Biol. Chem. , vol.254 , pp. 5972-5982
    • Sutter, A.1    Riopelle, R.J.2    Harris-Warrick, R.M.3    Shooter, E.M.4
  • 96
    • 0023133256 scopus 로고
    • Gene transfer and molecular cloning of the rat nerve growth factor receptor
    • Radeke M. J., Misko T. P., Hsu C., Herzenberg L. A., Shooter E. M. Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature. 325:1987;593-597.
    • (1987) Nature , vol.325 , pp. 593-597
    • Radeke, M.J.1    Misko, T.P.2    Hsu, C.3    Herzenberg, L.A.4    Shooter, E.M.5
  • 97
    • 0024999375 scopus 로고
    • Molecular cloning and neurotrophic activities of a protein with structural similarities to β-nerve growth factor: Developmental and topographical expression in the brain
    • Ernfors P., Ibáñez C. F., Ebendal T., Olson L., Persson H. Molecular cloning and neurotrophic activities of a protein with structural similarities to β-nerve growth factor: Developmental and topographical expression in the brain. Proc. Natl. Acad. Sci. USA. 87:1990;5454-5458.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5454-5458
    • Ernfors, P.1    Ibáñez, C.F.2    Ebendal, T.3    Olson, L.4    Persson, H.5
  • 98
    • 0025907893 scopus 로고
    • Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary
    • Hallböök F., Ibanez C. F., Persson H. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron. 6:1991;845-858.
    • (1991) Neuron , vol.6 , pp. 845-858
    • Hallböök, F.1    Ibanez, C.F.2    Persson, H.3
  • 99
    • 0029004721 scopus 로고
    • Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signaling
    • Ryden M., Murray-Rust J., Glass D., Ilag L. L., Trupp M., Yancopoulos G. D., McDonald N. Q., Ibáñez C. F. Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signaling. EMBO J. 14:1995;1979-1990.
    • (1995) EMBO J. , vol.14 , pp. 1979-1990
    • Ryden, M.1    Murray-Rust, J.2    Glass, D.3    Ilag, L.L.4    Trupp, M.5    Yancopoulos, G.D.6    McDonald, N.Q.7    Ibáñez, C.F.8
  • 100
    • 0028916394 scopus 로고
    • Functional interactions of neurotrophins and neurotrophin receptors
    • Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18:1995;223-253.
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 223-253
    • Bothwell, M.1
  • 101
    • 0030878081 scopus 로고    scopus 로고
    • The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity
    • Dechant G., Tsoulfas P., Parada L. F., Barde Y. A. The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity. J. Neurosci. 17:1997;5281-5287.
    • (1997) J. Neurosci. , vol.17 , pp. 5281-5287
    • Dechant, G.1    Tsoulfas, P.2    Parada, L.F.3    Barde, Y.A.4
  • 102
    • 0027299487 scopus 로고
    • Specific high affinity receptors for neurotrophin-3 on sympathetic neurons
    • Dechant G., Rodriguez-Tébar A., Kolbeck R., Barde Y.-A. Specific high affinity receptors for neurotrophin-3 on sympathetic neurons. J. Neurosci. 13:1993;2610-2616.
    • (1993) J. Neurosci. , vol.13 , pp. 2610-2616
    • Dechant, G.1    Rodriguez-Tébar, A.2    Kolbeck, R.3    Barde, Y.-A.4
  • 103
    • 0025774207 scopus 로고
    • High affinity NGF binding requires co-expression of the trk proto-oncogene and the low affinity NGF receptor
    • Hempstead B. L., Martin-Zanca D., Kaplan D. R., Chao M. V. High affinity NGF binding requires co-expression of the trk proto-oncogene and the low affinity NGF receptor. Nature. 350:1991;678-683.
    • (1991) Nature , vol.350 , pp. 678-683
    • Hempstead, B.L.1    Martin-Zanca, D.2    Kaplan, D.R.3    Chao, M.V.4
  • 104
    • 0027966170 scopus 로고
    • Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to trkA on PC12 cells
    • Barker P. A., Shooter E. M. Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to trkA on PC12 cells. Neuron. 13:1994;203-215.
    • (1994) Neuron , vol.13 , pp. 203-215
    • Barker, P.A.1    Shooter, E.M.2
  • 106
    • 0030945725 scopus 로고    scopus 로고
    • Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor
    • Rydén M., Hempstead B., Ibáñez C. F. Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor. J. Biol. Chem. 272:1997.
    • (1997) J. Biol. Chem. , vol.272
    • Rydén, M.1    Hempstead, B.2    Ibáñez, C.F.3
  • 107
    • 0028270620 scopus 로고
    • The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development
    • Barrett G. L., Bartlett P. The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development. Proc. Natl. Acad. Sci. USA. 91:1994;6501-6505.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6501-6505
    • Barrett, G.L.1    Bartlett, P.2
  • 108
    • 0027330994 scopus 로고
    • P75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
    • Davies A., Lee K.-F., Jaenisch R. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron. 11:1993;1-20.
    • (1993) Neuron , vol.11 , pp. 1-20
    • Davies, A.1    Lee, K.-F.2    Jaenisch, R.3
  • 109
    • 0028196552 scopus 로고
    • P75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF
    • Lee K. F., Davies A. M., Jaenisch R. p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF. Development. 120:1994;1027-1033.
    • (1994) Development , vol.120 , pp. 1027-1033
    • Lee, K.F.1    Davies, A.M.2    Jaenisch, R.3
  • 112
    • 0027528768 scopus 로고
    • Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells
    • Ip N. Y., Stitt T. N., Tapley P., Klein R., Glass D. J., Fandl J., Greene L. A., Barbacid M., Yancopoulos G. D. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron. 10:1993;137-149.
    • (1993) Neuron , vol.10 , pp. 137-149
    • Ip, N.Y.1    Stitt, T.N.2    Tapley, P.3    Klein, R.4    Glass, D.J.5    Fandl, J.6    Greene, L.A.7    Barbacid, M.8    Yancopoulos, G.D.9
  • 115
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji S. X., Majdan M., Pozniak C. D., Belliveau D. J., Aloyz R., Kohn J., Causing C. G., Miller F. D. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140:1998;911-923.
    • (1998) J. Cell Biol. , vol.140 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 116
    • 0344665622 scopus 로고    scopus 로고
    • Neurotrophins induce death of cultured hippocampal neurons
    • Friedman W. J., Grosman J. Neurotrophins induce death of cultured hippocampal neurons. Soc. Neurosci. Abstr. 25:1999;767.
    • (1999) Soc. Neurosci. Abstr. , vol.25 , pp. 767
    • Friedman, W.J.1    Grosman, J.2
  • 117
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade J. M., Barde Y. A. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron. 20:1998;35-41.
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 118
    • 0029829495 scopus 로고    scopus 로고
    • Survival of cholinergic forebrain neurons in developing p75 NGFR-deficient mice
    • van der Zee C. E. E., Ross G. M., Riopelle R. J., Hagg T. Survival of cholinergic forebrain neurons in developing p75 NGFR-deficient mice. Science. 274:1996;1729-1732.
    • (1996) Science , vol.274 , pp. 1729-1732
    • Van Der Zee, C.E.E.1    Ross, G.M.2    Riopelle, R.J.3    Hagg, T.4
  • 119
    • 0023856172 scopus 로고
    • Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: Ultrastructural localization, suppression by axonal contact, and binding properties
    • Taniuchi M., Clark H. B., Schweitzer J. B., Johnson E. M. J. Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: Ultrastructural localization, suppression by axonal contact, and binding properties. J. Neurosci. 8:1988;664-681.
    • (1988) J. Neurosci. , vol.8 , pp. 664-681
    • Taniuchi, M.1    Clark, H.B.2    Schweitzer, J.B.3    Johnson, E.M.J.4
  • 120
    • 0023864835 scopus 로고
    • Axons regulate Schwann cell expression of the major myelin and NGF receptor genes
    • Lemke G., Chao M. Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. Development. 102:1988;499-504.
    • (1988) Development , vol.102 , pp. 499-504
    • Lemke, G.1    Chao, M.2
  • 121
    • 0029805770 scopus 로고    scopus 로고
    • Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
    • Casaccia-Bonnefil P., Carter B. D., Dobrowsky R. T., Chao M. V. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature. 383:1996;716-719.
    • (1996) Nature , vol.383 , pp. 716-719
    • Casaccia-Bonnefil, P.1    Carter, B.D.2    Dobrowsky, R.T.3    Chao, M.V.4
  • 122
    • 0032520192 scopus 로고    scopus 로고
    • P75 neurotrophin receptor expression on adult human oligodendrocytes: Signaling without cell death in response to NGF
    • Ladiwala U., Lachance C., Simoneau S. J., Bhakar A., Barker P. A., Antel J. P. p75 neurotrophin receptor expression on adult human oligodendrocytes: Signaling without cell death in response to NGF. J. Neurosci. 18:1998;1297-1304.
    • (1998) J. Neurosci. , vol.18 , pp. 1297-1304
    • Ladiwala, U.1    Lachance, C.2    Simoneau, S.J.3    Bhakar, A.4    Barker, P.A.5    Antel, J.P.6
  • 123
    • 0039529731 scopus 로고    scopus 로고
    • Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway
    • Soilu-Hanninen M., Ekert P., Bucci T., Syroid D., Bartlett P. F., Kilpatrick T. J. Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway. J. Neurosci. 19:1999;4828-4838.
    • (1999) J. Neurosci. , vol.19 , pp. 4828-4838
    • Soilu-Hanninen, M.1    Ekert, P.2    Bucci, T.3    Syroid, D.4    Bartlett, P.F.5    Kilpatrick, T.J.6
  • 125
    • 0000326996 scopus 로고    scopus 로고
    • Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival
    • Yoon S. O., Casaccia-Bonnefil P., Carter B., Chao M. V. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. J. Neurosci. 18:1998;3273-3281.
    • (1998) J. Neurosci. , vol.18 , pp. 3273-3281
    • Yoon, S.O.1    Casaccia-Bonnefil, P.2    Carter, B.3    Chao, M.V.4
  • 126
    • 0007460987 scopus 로고    scopus 로고
    • TrkB signaling inhibits p75-mediated apoptosis induced by NGF in embryonic proprioceptive neurons
    • Davey F., Davies A. TrkB signaling inhibits p75-mediated apoptosis induced by NGF in embryonic proprioceptive neurons. Curr. Biol. 115:1998;56-67.
    • (1998) Curr. Biol. , vol.115 , pp. 56-67
    • Davey, F.1    Davies, A.2
  • 128
    • 0028108788 scopus 로고
    • Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor
    • Dobrowsky R., Werner M., Castellino A., Chao M., Hannun Y. Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science. 265:1994;1596-1599.
    • (1994) Science , vol.265 , pp. 1596-1599
    • Dobrowsky, R.1    Werner, M.2    Castellino, A.3    Chao, M.4    Hannun, Y.5
  • 129
    • 0029090337 scopus 로고
    • Neurotrophins induce sphingomyelin hydrolysis: Modulation by co-expression of p75 with trk receptors
    • Dobrowsky R. T., Jenkins G. M., Hannun Y. A. Neurotrophins induce sphingomyelin hydrolysis: Modulation by co-expression of p75 with trk receptors. J. Biol. Chem. 270:1995;22135-22142.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22135-22142
    • Dobrowsky, R.T.1    Jenkins, G.M.2    Hannun, Y.A.3
  • 130
    • 0026458406 scopus 로고
    • TNF activates NF-kB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
    • Schutze S., Potthof K., Machleidt T., Berkovic D., Wiegmann K., Kronke M. TNF activates NF-kB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell. 71:1992;765-776.
    • (1992) Cell , vol.71 , pp. 765-776
    • Schutze, S.1    Potthof, K.2    Machleidt, T.3    Berkovic, D.4    Wiegmann, K.5    Kronke, M.6
  • 131
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by Il-1B
    • Mathias S., Younes A., Kan C.-C., Orlow I., Joseph C., Kolesnick R. N. Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by Il-1B. Science. 259:1993;519-522.
    • (1993) Science , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.-C.3    Orlow, I.4    Joseph, C.5    Kolesnick, R.N.6
  • 132
    • 0033613831 scopus 로고    scopus 로고
    • Association of the p75 neurotrophin receptor with TRAF6
    • Khursigara G., Orlinick J. R., Chao M. V. Association of the p75 neurotrophin receptor with TRAF6. J. Biol. Chem. 274:1999;2597-2600.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2597-2600
    • Khursigara, G.1    Orlinick, J.R.2    Chao, M.V.3
  • 135
    • 0032517786 scopus 로고    scopus 로고
    • P53 is essential for developmental neuron death as regulated by the trkA and p75 neurotrophin receptors
    • Aloyz R. S., Bamji S. X., Pozniak C. D., Toma J. G., Atwal J., Kaplan D. R., Miller F. D. P53 is essential for developmental neuron death as regulated by the trkA and p75 neurotrophin receptors. J. Cell Biol. 143:1998;1691-1703.
    • (1998) J. Cell Biol. , vol.143 , pp. 1691-1703
    • Aloyz, R.S.1    Bamji, S.X.2    Pozniak, C.D.3    Toma, J.G.4    Atwal, J.5    Kaplan, D.R.6    Miller, F.D.7
  • 136
    • 0007400741 scopus 로고
    • Developmentally regulated expression of the nerve growth factor receptor gene in the periphery and brain
    • Buck C. R., Martinez H. J., Black I. B., Chao M. V. Developmentally regulated expression of the nerve growth factor receptor gene in the periphery and brain. Proc. Natl. Acad. Sci. USA. 84:1987;3060-3063.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3060-3063
    • Buck, C.R.1    Martinez, H.J.2    Black, I.B.3    Chao, M.V.4
  • 137
    • 0024468836 scopus 로고
    • Expression of NGF receptor in the rat forebrain detected with in situ hybridization and immunohistochemistry
    • Gibbs R. B., McCabe J. T., Buck C. R., Chao M. V., Pfaff D. W. Expression of NGF receptor in the rat forebrain detected with in situ hybridization and immunohistochemistry. Mol. Brain Res. 6:1989;275-287.
    • (1989) Mol. Brain Res. , vol.6 , pp. 275-287
    • Gibbs, R.B.1    McCabe, J.T.2    Buck, C.R.3    Chao, M.V.4    Pfaff, D.W.5
  • 138
    • 0025987885 scopus 로고
    • Temporal and spatial expression of NGF receptor mRNA during postnatal rat brain development analyzed by in situ hybridization
    • Friedman W. J., Olson L., Persson H. Temporal and spatial expression of NGF receptor mRNA during postnatal rat brain development analyzed by in situ hybridization. Dev. Brain Res. 63:1991;43-51.
    • (1991) Dev. Brain Res. , vol.63 , pp. 43-51
    • Friedman, W.J.1    Olson, L.2    Persson, H.3
  • 140
    • 0024365473 scopus 로고
    • Expression of NGF and NGF receptor mRNAs in the developing brain: Evidence for local delivery and action of NGF
    • Lu B., Buck C. R., Dreyfus C. F., Black I. B. Expression of NGF and NGF receptor mRNAs in the developing brain: Evidence for local delivery and action of NGF. Exp. Neurol. 104:1989;191-199.
    • (1989) Exp. Neurol. , vol.104 , pp. 191-199
    • Lu, B.1    Buck, C.R.2    Dreyfus, C.F.3    Black, I.B.4
  • 141
    • 0024380143 scopus 로고
    • Expression of high- and low-affinity nerve growth factor receptors by Purkinje cells in the developing rat cerebellum
    • Cohen-Cory S., Dreyfus C. F., Black I. B. Expression of high- and low-affinity nerve growth factor receptors by Purkinje cells in the developing rat cerebellum. Exp. Neurol. 105:1989;104-109.
    • (1989) Exp. Neurol. , vol.105 , pp. 104-109
    • Cohen-Cory, S.1    Dreyfus, C.F.2    Black, I.B.3
  • 142
    • 0024145347 scopus 로고
    • Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat
    • Ernfors P., Halböök F., Ebendal T., Shooter E. M., Radeke M. J., Misko T. P., Persson H. Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat. Neuron. 1:1988;983-996.
    • (1988) Neuron , vol.1 , pp. 983-996
    • Ernfors, P.1    Halböök, F.2    Ebendal, T.3    Shooter, E.M.4    Radeke, M.J.5    Misko, T.P.6    Persson, H.7
  • 143
    • 0024679252 scopus 로고
    • Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
    • Ernfors P., Henschen A., Olson L., Persson H. Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron. 2:1989;1605-1613.
    • (1989) Neuron , vol.2 , pp. 1605-1613
    • Ernfors, P.1    Henschen, A.2    Olson, L.3    Persson, H.4
  • 144
    • 0028670573 scopus 로고
    • Is p75NGFR involved in developmental neural cell death
    • Rabizadeh S., Bredesen D. E. Is p75NGFR involved in developmental neural cell death. Dev. Neurosci. 16:1994;207-211.
    • (1994) Dev. Neurosci. , vol.16 , pp. 207-211
    • Rabizadeh, S.1    Bredesen, D.E.2
  • 145
    • 0033566919 scopus 로고    scopus 로고
    • P75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
    • Roux P. P., Colicos M. A., Barker P. A., Kennedy T. E. p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. J. Neurosci. 19:1999;6887-6896.
    • (1999) J. Neurosci. , vol.19 , pp. 6887-6896
    • Roux, P.P.1    Colicos, M.A.2    Barker, P.A.3    Kennedy, T.E.4


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