Repair of γ-irradiation-induced DNA single-strand breaks in human bone marrow cells: Effects of a second irradiation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 373, Issue 1, 1997, Pages 31-37

  Lankinen, Maarit H ^a   Vilpo, Juhani A ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Base excision repair; Bone marrow cell; DNA repair; Ionizing irradiation

Indexed keywords

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; EXCISION REPAIR; GAMMA RADIATION; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

BONE MARROW; BONE MARROW CELLS; CELLS, CULTURED; CENTRIFUGATION, DENSITY GRADIENT; CESIUM RADIOISOTOPES; DNA FRAGMENTATION; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROPHORESIS; HUMANS; KINETICS; LEUKOCYTES, MONONUCLEAR; MICROSCOPY, FLUORESCENCE;

EID: 0031015126     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(96)00183-2     Document Type: Article

References (19)

1. Johns, H.E. and J.R. Cunningham (1983) The Physics of Radiobiology, 4th Edn. Springfield, IL, Charles C. Thomas.
2. Elkind, M.M. and H. Sutton (1960) Radiation response of mammalian cells grown in culture. I. Repair of x-ray damage in surviving Chinese hamster cells. Radiat. Res., 13, 556-562.
3. Hutchinson, F. (1985) Chemical changes induced in DNA by ionizing radiation. Prog. Nucleic Acid Res. Mol. Biol., 32, 115-154.
4. Teoule, R. (1987) Radiation-induced DNA damage and its repair. Int. J. Radiat. Biol., 51, 573-589.
5. von Sonntag, C. (1987) The Chemical Basis of Radiation Biology. Taylor & Francis, London.
6. Price, A. (1993) The repair of ionizing radiation-induced damage to DNA. Cancer Biol., 4, 61-71.
7. Friedberg, E.C., G.C. Walker and W. Siede (1995) DNA repair and mutagenesis, ASM Press, Washington, DC.
8. Singh, N.P., M.T. McCoy, R.R. Tice and E.L. Schneider (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
9. Boyum, A., D. Lovhaug, L. Tresland and E.M. Nordlie (1991) Separation of leucocytes: improved cell purity by fine adjustments of gradient medium density and osmolality. Scand. J. Immunol., 34, 697-712.
10. Lankinen, M.H, L.M. Vilpo and J.A. Vilpo (1996) UV- and γ-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes. Mutation Res., 352, 31-38.
11. Rothstein, G. (1993) Origin and development of the blood and blood-forming tissues, in: G.H. Lee, T.C. Bithell, J. Foerster, J.W. Athens and J.N. Lukens (Eds.), Wintrobe's Clinical Hematology, 9th Edn., Lea & Febriger, Philadelphia, pp. 41-78.
12. Vilpo, J.A. (1988) The DNA-repair enzyme uracil-DNA glycosylase in the human hematopoietic system. Mutation Res., 193, 207-217.
13. Olive, P.L. and J.P. Banáth (1993) Induction and rejoining of radiation-induced DNA single-strand breaks: 'tail moment' as a function of position in the cell cycle. Mutation Res., 294, 275-283.
14. Homberg, K., S. Fält, A. Johansson and B. Lambert (1993) Clonal chromosome aberrations and karyotypic instability in X-irradiated human T-lymphocytes. Mutation Res., 286, 321-330.
15. Hendry, J.H. and Y. Feng-Tong (1995) Response of bone marrow to low LET irradiation, in: J.H. Hendry and B.I. Lord (Eds.), Radiation Toxicology. Bone Marrow and Leukaemia, Taylor & Francis, London, pp. 91-116.
16. Mauch, P., L. Constine, J. Greenberger, W. Knospe, J. Sullivan, J.L. Liesveld and H.J. Deeg (1995) Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy. Int. J. Radiat. Oncol. Biol. Phys., 31, 1319-1339.
17. Ward, J.F. (1985) Biochemistry of DNA lesions. Radiat. Res., 104, 103-111.
18. Ward, J.F. (1986) Mechanisms of DNA repair and their potential modification for radiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 12, 1027-1032.
19. Frankenberg-Schwater, M. (1989) Review of kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation. Radiother. Oncol., 14, 307-320.