Use of the comet assay to investigate possible interactions of nitric oxide and reactive oxygen species in the induction of DNA damage and inhibition of function in an insulin-secreting cell line

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 375, Issue 2, 1997, Pages 137-146

  Delaney, Carol A ^a,b   Green, Irene C ^a   Lowe, Jillian E ^a   Cunningham, James M ^a   Butler, Anthony R ^c   Renton, Louise ^c   D'Costa, Ieta ^a,d   Green, Michael H L ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF ST ANDREWS   (United Kingdom)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

3 Morpholinosydnonimine (SIN 1); Catalase; Comet assay (single cell gel electrophoresis); DNA damage; DNA synthesis; Insulin secreting cells; Nitric oxide; Roussin's black salt (heptanitrosyltri 3 thioxotetraferrate(1 )); S Nitrosoglutathione; Superoxide dismutase; Superoxide Hydrogen peroxide

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; LINSIDOMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; S NITROSOGLUTATHIONE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DNA SYNTHESIS; GEL ELECTROPHORESIS; HAMSTER; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL; PRIORITY JOURNAL;

ANIMALS; CATALASE; CELL LINE; CRICETINAE; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; INSULIN; MUTAGENS; NITRATES; NITRIC OXIDE; NITRITES; REACTIVE OXYGEN SPECIES; SECRETORY RATE; SUPEROXIDE DISMUTASE;

ANIMALIA; CRICETINAE;

EID: 0030915040     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00009-2     Document Type: Article

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