-
1
-
-
0025234628
-
Type-1 diabetes: A chronic autoimmune disease of human, mouse and rat
-
Castano L & Eisenbarth GS (1991). Type-1 diabetes: a chronic autoimmune disease of human, mouse and rat. Annual Review of Immunology, 8: 647-679.
-
(1991)
Annual Review of Immunology
, vol.8
, pp. 647-679
-
-
Castano, L.1
Eisenbarth, G.S.2
-
2
-
-
0027293874
-
Repair of pancreatic β-cells. A relevant phenomenon in early IDDM?
-
Eizirik DL, Sandler S & Palmer JP (1993). Repair of pancreatic β-cells. A relevant phenomenon in early IDDM? Diabetes, 42: 1383-1391.
-
(1993)
Diabetes
, vol.42
, pp. 1383-1391
-
-
Eizirik, D.L.1
Sandler, S.2
Palmer, J.P.3
-
3
-
-
0025197945
-
Cytokines and free radicals as effector molecules in the destruction of pancreatic β cells
-
Baekkeskov S & Hansen B (Editors), Springer, Berlin, Heidelberg, New York
-
Mandrup-Poulsen T, Helqvist S, Wogensen LD, Molvig J, Pociot F & Nerup J (1990). Cytokines and free radicals as effector molecules in the destruction of pancreatic β cells. In: Baekkeskov S & Hansen B (Editors), Human Diabetes - Genetic, Environmental and Autoimmune Etiology. Springer, Berlin, Heidelberg, New York, 166-193.
-
(1990)
Human Diabetes - Genetic, Environmental and Autoimmune Etiology
, pp. 166-193
-
-
Mandrup-Poulsen, T.1
Helqvist, S.2
Wogensen, L.D.3
Molvig, J.4
Pociot, F.5
Nerup, J.6
-
4
-
-
0000836601
-
Role of cytokines in IDDM pathogenesis and islet β-cell destruction
-
Rabinovitch A (1993). Role of cytokines in IDDM pathogenesis and islet β-cell destruction. Diabetes Review, 1: 215-240.
-
(1993)
Diabetes Review
, vol.1
, pp. 215-240
-
-
Rabinovitch, A.1
-
5
-
-
0026079608
-
Biochemical and molecular actions of interleukin-1β on pancreatic β-cells
-
Sandler S, Eizirik DL, Svensson C, Strandell E, Welsh M & Welsh N (1991). Biochemical and molecular actions of interleukin-1β on pancreatic β-cells. Autoimmunity, 10: 241-253.
-
(1991)
Autoimmunity
, vol.10
, pp. 241-253
-
-
Sandler, S.1
Eizirik, D.L.2
Svensson, C.3
Strandell, E.4
Welsh, M.5
Welsh, N.6
-
6
-
-
0027534895
-
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans
-
Corbett JA, Sweetland MA, Wang JL, Lancaster Jr JR & McDaniel ML (1993). Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. Proceedings of the National Academy of Sciences, USA, 90: 1731-1735.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 1731-1735
-
-
Corbett, J.A.1
Sweetland, M.A.2
Wang, J.L.3
Lancaster Jr., J.R.4
McDaniel, M.L.5
-
7
-
-
0028296629
-
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation
-
Eizirik DL, Sandler S, Welsh N, Cetkovic-Cvrlje M, Nieman A, Geller DA, Pipeleers DG, Bendtzen K & Hellerström C (1994). Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. Journal of Clinical Investigation, 93: 1968-1974.
-
(1994)
Journal of Clinical Investigation
, vol.93
, pp. 1968-1974
-
-
Eizirik, D.L.1
Sandler, S.2
Welsh, N.3
Cetkovic-Cvrlje, M.4
Nieman, A.5
Geller, D.A.6
Pipeleers, D.G.7
Bendtzen, K.8
Hellerström, C.9
-
8
-
-
0028902552
-
Nitric oxide syntheses: Properties and catalytic mechanism
-
Griffith OW & Stuher DJ (1995). Nitric oxide syntheses: properties and catalytic mechanism. Annual Review of Physiology, 57: 707-736.
-
(1995)
Annual Review of Physiology
, vol.57
, pp. 707-736
-
-
Griffith, O.W.1
Stuher, D.J.2
-
9
-
-
0028035106
-
The high-output nitric oxide pathway: Role and regulation
-
Xie Q-W & Nathan C (1994). The high-output nitric oxide pathway: role and regulation. Journal of Leukocyte Biology, 56: 576-582.
-
(1994)
Journal of Leukocyte Biology
, vol.56
, pp. 576-582
-
-
Xie, Q.-W.1
Nathan, C.2
-
10
-
-
0028922422
-
Nitric oxide: Pathophysiological mechanisms
-
Gross SS (1995). Nitric oxide: pathophysiological mechanisms. Annual Review of Physiology, 57: 737-769.
-
(1995)
Annual Review of Physiology
, vol.57
, pp. 737-769
-
-
Gross, S.S.1
-
11
-
-
0025685395
-
Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism
-
Southern C, Schulster D & Green IC (1990). Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism. FEBS Letters, 276: 42-44.
-
(1990)
FEBS Letters
, vol.276
, pp. 42-44
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
12
-
-
0028626360
-
The inducible form of nitric oxide synthase (iNOS) in insulin-producing cells
-
Eizirik DL & Leijerstam F (1994). The inducible form of nitric oxide synthase (iNOS) in insulin-producing cells. Diabetes and Metabolism, 20: 116-122.
-
(1994)
Diabetes and Metabolism
, vol.20
, pp. 116-122
-
-
Eizirik, D.L.1
Leijerstam, F.2
-
13
-
-
0028633557
-
Cytokines, nitric oxide and insulin secreting cells
-
Cunningham JM & Green IC (1994). Cytokines, nitric oxide and insulin secreting cells. Growth Regulation, 4: 173-180.
-
(1994)
Growth Regulation
, vol.4
, pp. 173-180
-
-
Cunningham, J.M.1
Green, I.C.2
-
14
-
-
0026683354
-
Does nitric oxide mediate autoimmune destruction of β-cells?
-
Corbett JA & McDaniel ML (1992). Does nitric oxide mediate autoimmune destruction of β-cells? Diabetes, 41: 897-903.
-
(1992)
Diabetes
, vol.41
, pp. 897-903
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
15
-
-
0026684463
-
Type 1 (insulin-dependent) diabetes mellitus and nitric oxide
-
Kolb H & Kolb-Bachofen V (1992). Type 1 (insulin-dependent) diabetes mellitus and nitric oxide. Diabetologia, 35: 796-797.
-
(1992)
Diabetologia
, vol.35
, pp. 796-797
-
-
Kolb, H.1
Kolb-Bachofen, V.2
-
16
-
-
0028049833
-
Major species differences between man and rodents in the susceptibility to pancreatic β-cell injury
-
Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerström C & Andersson A (1994). Major species differences between man and rodents in the susceptibility to pancreatic β-cell injury. Proceedings of the National Academy of Sciences, USA, 91: 9253-9256.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 9253-9256
-
-
Eizirik, D.L.1
Pipeleers, D.G.2
Ling, Z.3
Welsh, N.4
Hellerström, C.5
Andersson, A.6
-
17
-
-
0028054338
-
Nitric oxide and pancreatic β-cell destruction in insulin dependent diabetes mellitus: Don't take NO for an answer
-
Welsh N, Eizirik DL & Sandler S (1994). Nitric oxide and pancreatic β-cell destruction in insulin dependent diabetes mellitus: don't take NO for an answer. Autoimmunity, 18: 285-290.
-
(1994)
Autoimmunity
, vol.18
, pp. 285-290
-
-
Welsh, N.1
Eizirik, D.L.2
Sandler, S.3
-
18
-
-
0028596498
-
Studies on the molecular regulation of the inducible form of nitric oxide synthase (NOS) in insulin-producing cells
-
Niemann A, Björklund A & Eizirik DL (1994). Studies on the molecular regulation of the inducible form of nitric oxide synthase (NOS) in insulin-producing cells. Molecular and Cellular Endocrinology, 106: 151-155.
-
(1994)
Molecular and Cellular Endocrinology
, vol.106
, pp. 151-155
-
-
Niemann, A.1
Björklund, A.2
Eizirik, D.L.3
-
19
-
-
0029092387
-
Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells
-
Bedoya FJ, Flodström M & Eizirik DL (1995). Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells. Biochemical and Biophysical Research Communications, 210: 816-822.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.210
, pp. 816-822
-
-
Bedoya, F.J.1
Flodström, M.2
Eizirik, D.L.3
-
20
-
-
0029082331
-
Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans
-
Karlsen AE, Andersen HU, Vissing H, Larsen PM, Fey SJ, Cuartero BG, Madsen OD, Petersen JS, Mortensen SB, Mandrup-Poulsen T, Boel E & Nerup J (1995). Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans. Diabetes, 44: 753-758.
-
(1995)
Diabetes
, vol.44
, pp. 753-758
-
-
Karlsen, A.E.1
Andersen, H.U.2
Vissing, H.3
Larsen, P.M.4
Fey, S.J.5
Cuartero, B.G.6
Madsen, O.D.7
Petersen, J.S.8
Mortensen, S.B.9
Mandrup-Poulsen, T.10
Boel, E.11
Nerup, J.12
-
21
-
-
0024240524
-
Functional characteristics of rat pancreatic islets maintained in culture following exposure to human interleukin-1
-
Eizirik DL, Strandell E, Bendtzen K & Sandler S (1988). Functional characteristics of rat pancreatic islets maintained in culture following exposure to human interleukin-1. Diabetes, 37: 916-919.
-
(1988)
Diabetes
, vol.37
, pp. 916-919
-
-
Eizirik, D.L.1
Strandell, E.2
Bendtzen, K.3
Sandler, S.4
-
22
-
-
0023899820
-
Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures
-
Rabinovitch A, Clifford P & Baquerizo H (1988). Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures. Endocrinology, 122: 2393-2398.
-
(1988)
Endocrinology
, vol.122
, pp. 2393-2398
-
-
Rabinovitch, A.1
Clifford, P.2
Baquerizo, H.3
-
23
-
-
0024405152
-
Differential sensitivity to β-cell secretagogues in cultured rat pancreatic islets exposed to human interleukin-1β
-
Eizirik DL, Sandler S, Hallberg A, Bendtzen K, Sener A & Malaisse WJ (1989). Differential sensitivity to β-cell secretagogues in cultured rat pancreatic islets exposed to human interleukin-1β. Endocrinology, 125: 752-759.
-
(1989)
Endocrinology
, vol.125
, pp. 752-759
-
-
Eizirik, D.L.1
Sandler, S.2
Hallberg, A.3
Bendtzen, K.4
Sener, A.5
Malaisse, W.J.6
-
24
-
-
0026606220
-
Glucose-sensing by the pancreatic B-cell: The mitochondrial part
-
Malaisse WJ (1992). Glucose-sensing by the pancreatic B-cell: the mitochondrial part. International Journal of Biochemistry, 24: 693-701.
-
(1992)
International Journal of Biochemistry
, vol.24
, pp. 693-701
-
-
Malaisse, W.J.1
-
25
-
-
0023203183
-
Inhibitory effects of interleukin-1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets
-
Sandler S, Andersson A & Hellerström C (1987). Inhibitory effects of interleukin-1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets. Endocrinology, 121: 1424-1431.
-
(1987)
Endocrinology
, vol.121
, pp. 1424-1431
-
-
Sandler, S.1
Andersson, A.2
Hellerström, C.3
-
26
-
-
0023768414
-
Interleukin-1 induced impairment in pancreatic islet oxidative metabolism is potentiated by tumor necrosis factor
-
Eizirik DL (1988). Interleukin-1 induced impairment in pancreatic islet oxidative metabolism is potentiated by tumor necrosis factor. Acta Endocrinologica, 119: 321-325.
-
(1988)
Acta Endocrinologica
, vol.119
, pp. 321-325
-
-
Eizirik, D.L.1
-
27
-
-
0025221587
-
Short-term exposure of rat pancreatic islets to human interleukin-1β increases cellular uptake of calcium
-
Borg LAH & Eizirik DL (1990). Short-term exposure of rat pancreatic islets to human interleukin-1β increases cellular uptake of calcium. Immunology Letters, 26: 253-258.
-
(1990)
Immunology Letters
, vol.26
, pp. 253-258
-
-
Borg, L.A.H.1
Eizirik, D.L.2
-
28
-
-
0027285626
-
Exogenous nitric oxide (NO) generation or IL-1β-induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase in RINm5F cells
-
Dimmeler S, Ankarcrona M, Nicotera P & Brüne B (1993). Exogenous nitric oxide (NO) generation or IL-1β-induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase in RINm5F cells. Journal of Immunology, 150: 2964-2971.
-
(1993)
Journal of Immunology
, vol.150
, pp. 2964-2971
-
-
Dimmeler, S.1
Ankarcrona, M.2
Nicotera, P.3
Brüne, B.4
-
29
-
-
0025833992
-
Interleukin-1β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
-
Welsh N, Eizirik DL, Bendtzen K & Sandler S (1991). Interleukin-1β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology, 129: 3167-3173.
-
(1991)
Endocrinology
, vol.129
, pp. 3167-3173
-
-
Welsh, N.1
Eizirik, D.L.2
Bendtzen, K.3
Sandler, S.4
-
30
-
-
0025731384
-
Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes
-
Stadler J, Billiar TR, Curran RD, Stuehr DJ, Ochoa JB & Simmonds RC (1991). Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. American Journal of Physiology, 260: C910-C916.
-
(1991)
American Journal of Physiology
, vol.260
-
-
Stadler, J.1
Billiar, T.R.2
Curran, R.D.3
Stuehr, D.J.4
Ochoa, J.B.5
Simmonds, R.C.6
-
31
-
-
0027960215
-
Superoxide and peroxynitrite inactivate aconitase, nitric oxide does not
-
Hausladen A & Fridovich I (1994). Superoxide and peroxynitrite inactivate aconitase, nitric oxide does not. Journal of Biological Chemistry, 269: 29405-29408.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 29405-29408
-
-
Hausladen, A.1
Fridovich, I.2
-
32
-
-
0028090219
-
Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide
-
Castro L, Rodriquez M & Radi R (1994). Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide. Journal of Biological Chemistry, 269: 29409-29415.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 29409-29415
-
-
Castro, L.1
Rodriquez, M.2
Radi, R.3
-
33
-
-
0028084944
-
Succinic acid monomethyl ester protects rat pancreatic islet secretory potential against interleukin-1β (IL-1β) without affecting glutamate decarboxylase expression or nitric oxide production
-
Eizirik DL, Welsh N, Niemann A, Velloso LA & Malaisse WJ (1994). Succinic acid monomethyl ester protects rat pancreatic islet secretory potential against interleukin-1β (IL-1β) without affecting glutamate decarboxylase expression or nitric oxide production. FEBS Letters, 337: 298-302.
-
(1994)
FEBS Letters
, vol.337
, pp. 298-302
-
-
Eizirik, D.L.1
Welsh, N.2
Niemann, A.3
Velloso, L.A.4
Malaisse, W.J.5
-
34
-
-
0023607389
-
Murine macrophages and pancreatic β-cells. Chemotactic properties of insulin and β-cytostatic action of interleukin-1
-
Leiter E (1987). Murine macrophages and pancreatic β-cells. Chemotactic properties of insulin and β-cytostatic action of interleukin-1. Journal of Experimental Medicine, 166: 1174-1179.
-
(1987)
Journal of Experimental Medicine
, vol.166
, pp. 1174-1179
-
-
Leiter, E.1
-
35
-
-
0025009733
-
Interleukin-1β depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism
-
Eizirik DL, Welsh M, Strandell E, Welsh N & Sandler S (1990). Interleukin-1β depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism. Endocrinology, 127: 2290-2297.
-
(1990)
Endocrinology
, vol.127
, pp. 2290-2297
-
-
Eizirik, D.L.1
Welsh, M.2
Strandell, E.3
Welsh, N.4
Sandler, S.5
-
36
-
-
0026556675
-
Interleukin-1β induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets
-
Welsh N & Sandler S (1992). Interleukin-1β induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets. Biochemical and Biophysical Research Communications, 182: 333-340.
-
(1992)
Biochemical and Biophysical Research Communications
, vol.182
, pp. 333-340
-
-
Welsh, N.1
Sandler, S.2
-
37
-
-
0025995444
-
Interleukin-1β induces an early decrease in insulin release, (pro)insulin biosynthesis and insulin mRNA in mouse pancreatic islets by a mechanism dependent on gene transcription and protein synthesis
-
Eizirik DL (1991). Interleukin-1β induces an early decrease in insulin release, (pro)insulin biosynthesis and insulin mRNA in mouse pancreatic islets by a mechanism dependent on gene transcription and protein synthesis. Autoimmunity, 10: 107-114.
-
(1991)
Autoimmunity
, vol.10
, pp. 107-114
-
-
Eizirik, D.L.1
-
38
-
-
0027934873
-
TNF-α and IFN-γ potentiate the deleterious effects of IL-1β on mouse pancreatic islets mainly via the generation of nitric oxide
-
Cetkovic-Cvrlje M & Eizirik DL (1994). TNF-α and IFN-γ potentiate the deleterious effects of IL-1β on mouse pancreatic islets mainly via the generation of nitric oxide, Cytokine, 6: 399-406.
-
(1994)
Cytokine
, vol.6
, pp. 399-406
-
-
Cetkovic-Cvrlje, M.1
Eizirik, D.L.2
-
39
-
-
0024584020
-
A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
-
Stuehr DJ & Nathan CF (1989). A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. Journal of Experimental Medicine, 169: 1543-1555.
-
(1989)
Journal of Experimental Medicine
, vol.169
, pp. 1543-1555
-
-
Stuehr, D.J.1
Nathan, C.F.2
-
40
-
-
28044464985
-
Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative disease
-
Cleeter MWJ, Cooper JM, Darley-Usmar VM, Moncada S & Schapira AHV (1994). Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative disease. FEBS Letters, 345: 50-54.
-
(1994)
FEBS Letters
, vol.345
, pp. 50-54
-
-
Cleeter, M.W.J.1
Cooper, J.M.2
Darley-Usmar, V.M.3
Moncada, S.4
Schapira, A.H.V.5
-
41
-
-
0028145462
-
Nitric oxide-mediated inhibition of the mitochondnal respiratory chain in cultured astrocytes
-
Bolaños JP, Peuchen S, Reales SJR, Land JM & Clark JB (1994). Nitric oxide-mediated inhibition of the mitochondnal respiratory chain in cultured astrocytes. Journal of Neurochemistry, 63: 910-916.
-
(1994)
Journal of Neurochemistry
, vol.63
, pp. 910-916
-
-
Bolaños, J.P.1
Peuchen, S.2
Reales, S.J.R.3
Land, J.M.4
Clark, J.B.5
-
42
-
-
0028791996
-
The effects of nitric oxide on the membrane potential and ionic currents of mouse pancreatic B cells
-
Krippeit-Drews P, Kröncke K-D, Welker S, Zempel G, Roenfeldt M, Ammon HP, Lang F & Drews G (1995). The effects of nitric oxide on the membrane potential and ionic currents of mouse pancreatic B cells. Endocrinology, 136: 5363-5369.
-
(1995)
Endocrinology
, vol.136
, pp. 5363-5369
-
-
Krippeit-Drews, P.1
Kröncke, K.-D.2
Welker, S.3
Zempel, G.4
Roenfeldt, M.5
Ammon, H.P.6
Lang, F.7
Drews, G.8
-
43
-
-
0028220671
-
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
-
Bolotina VM, Najibi S, Palacino JJ, Pagano PJ & Cohen RA (1994). Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature, 368: 850-853.
-
(1994)
Nature
, vol.368
, pp. 850-853
-
-
Bolotina, V.M.1
Najibi, S.2
Palacino, J.J.3
Pagano, P.J.4
Cohen, R.A.5
-
45
-
-
0026522884
-
DNA damage and mutation in human cells exposed to nitric oxide in vitro
-
Nguyen T, Brunson D, Crespi CL, Penman BW, Wishnok JS & Tannenbaum SR (1992). DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proceedings of the National Academy of Sciences, USA, 89: 3030-3034.
-
(1992)
Proceedings of the National Academy of Sciences, USA
, vol.89
, pp. 3030-3034
-
-
Nguyen, T.1
Brunson, D.2
Crespi, C.L.3
Penman, B.W.4
Wishnok, J.S.5
Tannenbaum, S.R.6
-
46
-
-
0027536123
-
Islet DNA is a target of inflammatory attack by nitric oxide
-
Fehsel K, Jalowy A, Qi S, Burkart V, Hartmann B & Kolb H (1993). Islet DNA is a target of inflammatory attack by nitric oxide. Diabetes, 42: 496-500.
-
(1993)
Diabetes
, vol.42
, pp. 496-500
-
-
Fehsel, K.1
Jalowy, A.2
Qi, S.3
Burkart, V.4
Hartmann, B.5
Kolb, H.6
-
47
-
-
0027428461
-
Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
-
Delaney CA, Green MHL, Lowe JE & Green IC (1993). Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Letters, 333: 291-295.
-
(1993)
FEBS Letters
, vol.333
, pp. 291-295
-
-
Delaney, C.A.1
Green, M.H.L.2
Lowe, J.E.3
Green, I.C.4
-
48
-
-
0028258386
-
Mechanisms of cytokine-induced destruction of rat insulinoma cells: The role of nitric oxide
-
Suarez-Pinzon WL, Strynadka K, Schulz R & Rabinovitch A (1994). Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide. Endocrinology, 134: 1006-1010.
-
(1994)
Endocrinology
, vol.134
, pp. 1006-1010
-
-
Suarez-Pinzon, W.L.1
Strynadka, K.2
Schulz, R.3
Rabinovitch, A.4
-
49
-
-
84889511366
-
DNA damage in neonatal rat islets caused by the combination of tumour necrosis factor-alpha and interferon-gamma
-
Delaney CA, Dunger A, Green MHL, Bone AJ & Green IC (1994). DNA damage in neonatal rat islets caused by the combination of tumour necrosis factor-alpha and interferon-gamma. Diabetologia, 37: A44.
-
(1994)
Diabetologia
, vol.37
-
-
Delaney, C.A.1
Dunger, A.2
Green, M.H.L.3
Bone, A.J.4
Green, I.C.5
-
50
-
-
0028074995
-
DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction
-
Rabinovitch A, Suarez-Pinzon WL, Shi Y, Morgan AR & Bleackley RC (1994). DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction. Diabetologia, 37: 733-738.
-
(1994)
Diabetologia
, vol.37
, pp. 733-738
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Shi, Y.3
Morgan, A.R.4
Bleackley, R.C.5
-
51
-
-
84889549744
-
Nitric oxide induced by tumor necrosis factor-alpha and interferon-gamma inhibits insulin secretion and causes DNA damage in neonatal rat islets
-
in press
-
Dunger A, Cunningham JM, Delaney CA, Green MHL, Bone AJ & Green IC (1996). Nitric oxide induced by tumor necrosis factor-alpha and interferon-gamma inhibits insulin secretion and causes DNA damage in neonatal rat islets. Diabetes (in press).
-
(1996)
Diabetes
-
-
Dunger, A.1
Cunningham, J.M.2
Delaney, C.A.3
Green, M.H.L.4
Bone, A.J.5
Green, I.C.6
-
52
-
-
0011818260
-
Effects of nitric oxide on DNA damage and ultrastructure in islets of Langerhans - A comparison of human and rodent
-
Delaney CA, Eizirik DL, Lowe JE, Green MHL, Thorpe JR, Pipeleers DG, Hellerström C & Green IC (1995). Effects of nitric oxide on DNA damage and ultrastructure in islets of Langerhans - a comparison of human and rodent. Diabetologia, 38: A17.
-
(1995)
Diabetologia
, vol.38
-
-
Delaney, C.A.1
Eizirik, D.L.2
Lowe, J.E.3
Green, M.H.L.4
Thorpe, J.R.5
Pipeleers, D.G.6
Hellerström, C.7
Green, I.C.8
-
53
-
-
0029915909
-
Nitric oxide donors decrease the function and survival of human pancreatic islets
-
in press
-
Eizirik DL, Delaney CA, Green MHL, Cunningham JM, Thorpe JR, Pipeleers DG, Hellerström C & Green IC (1996). Nitric oxide donors decrease the function and survival of human pancreatic islets. Molecular and Cellular Endocrinology (in press).
-
(1996)
Molecular and Cellular Endocrinology
-
-
Eizirik, D.L.1
Delaney, C.A.2
Green, M.H.L.3
Cunningham, J.M.4
Thorpe, J.R.5
Pipeleers, D.G.6
Hellerström, C.7
Green, I.C.8
-
54
-
-
0027977269
-
It was a good year for DNA repair
-
Cleaver J (1994). It was a good year for DNA repair. Cell, 76: 1-4.
-
(1994)
Cell
, vol.76
, pp. 1-4
-
-
Cleaver, J.1
-
55
-
-
0028919809
-
Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA
-
de Rojas-Walker T, Tamir S, Ji H, Wishnok JS & Tannenbaum SR (1995). Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA. Chemical Research in Toxicology, 8: 473-477.
-
(1995)
Chemical Research in Toxicology
, vol.8
, pp. 473-477
-
-
De Rojas-Walker, T.1
Tamir, S.2
Ji, H.3
Wishnok, J.S.4
Tannenbaum, S.R.5
-
57
-
-
0027955137
-
Review of the genotoxicity of nitrogen oxides
-
Victorin K (1994). Review of the genotoxicity of nitrogen oxides. Mutation Research, 317: 43-55.
-
(1994)
Mutation Research
, vol.317
, pp. 43-55
-
-
Victorin, K.1
-
58
-
-
0029111530
-
Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
-
Inoue S & Kawanishi S (1995). Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Letters, 371: 86-88.
-
(1995)
FEBS Letters
, vol.371
, pp. 86-88
-
-
Inoue, S.1
Kawanishi, S.2
-
60
-
-
0025938548
-
Inhibition of tumour cell ribonucleotide reductase by macrophage-derived nitric oxide
-
Kwon NS, Stuehr DJ & Nathan CF (1991). Inhibition of tumour cell ribonucleotide reductase by macrophage-derived nitric oxide. Journal of Experimental Medicine, 174: 762-767.
-
(1991)
Journal of Experimental Medicine
, vol.174
, pp. 762-767
-
-
Kwon, N.S.1
Stuehr, D.J.2
Nathan, C.F.3
-
61
-
-
0026490231
-
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide
-
Lepoivre M, Flaman JM & Henry Y (1992). Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide. Journal of Biological Chemistry, 267: 22994-23000.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 22994-23000
-
-
Lepoivre, M.1
Flaman, J.M.2
Henry, Y.3
-
62
-
-
0028181674
-
6-methylguanine-DNA-methyltransferase
-
6-methylguanine-DNA-methyltransferase. Carcinogenesis, 15: 443-447.
-
(1994)
Carcinogenesis
, vol.15
, pp. 443-447
-
-
Laval, F.1
Wink, D.A.2
-
63
-
-
84889515762
-
The effect of nitric oxide on DNA synthesis and DNA damage in insulin-secreting cells
-
Delaney CA, Green MHL, Belgore F & Green IC (1994). The effect of nitric oxide on DNA synthesis and DNA damage in insulin-secreting cells. Diabetic Medicine, 11: A31.
-
(1994)
Diabetic Medicine
, vol.11
-
-
Delaney, C.A.1
Green, M.H.L.2
Belgore, F.3
Green, I.C.4
-
65
-
-
0002423940
-
The molecular basis of experimental diabetes
-
Okamoto H (Editor), Cambridge University Press, Cambridge
-
Okamoto H (1990). The molecular basis of experimental diabetes. In: Okamoto H (Editor), Molecular Biology of the Islets of Langerhans. Cambridge University Press, Cambridge, 209-231.
-
(1990)
Molecular Biology of the Islets of Langerhans
, pp. 209-231
-
-
Okamoto, H.1
-
66
-
-
0028276094
-
Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD depletion
-
Radons J, Heller B, Bürkle A, Hartmann B, Rodriguez M-L, Kröncke K-D, Burkart V & Kolb H (1994). Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD depletion. Biochemical and Biophysical Research Communications, 199: 1270-1277.
-
(1994)
Biochemical and Biophysical Research Communications
, vol.199
, pp. 1270-1277
-
-
Radons, J.1
Heller, B.2
Bürkle, A.3
Hartmann, B.4
Rodriguez, M.-L.5
Kröncke, K.-D.6
Burkart, V.7
Kolb, H.8
-
68
-
-
0027955580
-
Interrelationship of changes in islet nicotine adenine dinucleotide, insulin secretion, and cell viability induced by interleukin-1β
-
Bolaffi JL, Rodd GG, Wang J & Grodsky GM (1994). Interrelationship of changes in islet nicotine adenine dinucleotide, insulin secretion, and cell viability induced by interleukin-1β. Endocrinology, 134: 537-542.
-
(1994)
Endocrinology
, vol.134
, pp. 537-542
-
-
Bolaffi, J.L.1
Rodd, G.G.2
Wang, J.3
Grodsky, G.M.4
-
69
-
-
0029017038
-
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells
-
Heller B, Wang Z-Q, Wagner EF, Radons J, Bürkle A, Fehsel K, Burkart V & Kolb H (1995). Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. Journal of Biological Chemistry, 270: 11176-11180.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 11176-11180
-
-
Heller, B.1
Wang, Z.-Q.2
Wagner, E.F.3
Radons, J.4
Bürkle, A.5
Fehsel, K.6
Burkart, V.7
Kolb, H.8
-
70
-
-
0026670335
-
Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview
-
Wyllie AH (1992). Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Review, 11: 95-103.
-
(1992)
Cancer Metastasis Review
, vol.11
, pp. 95-103
-
-
Wyllie, A.H.1
-
71
-
-
0026522112
-
The origins of DNA breaks: A consequence of DNA damage, DNA repair, or apoptosis
-
Eastman A & Barry MA (1992). The origins of DNA breaks: a consequence of DNA damage, DNA repair, or apoptosis. Cancer Investigations, 10: 229-240.
-
(1992)
Cancer Investigations
, vol.10
, pp. 229-240
-
-
Eastman, A.1
Barry, M.A.2
-
73
-
-
0027265740
-
2+ channels exposed to serum from patients with type 1 diabetes
-
2+ channels exposed to serum from patients with type 1 diabetes. Science, 261: 86-90.
-
(1993)
Science
, vol.261
, pp. 86-90
-
-
Juntti-Berggren, L.1
Larsson, O.2
Rorsman, P.3
Ammala, C.4
Bokvist, K.5
Wahlander, K.6
Nicotera, P.7
Dypbukt, J.8
Orrenius, S.9
Hallberg, A.10
Berggren, P.-O.11
-
74
-
-
0027488644
-
Sensitivity of insulin-secreting RINm5F cells to undergoing apoptosis by the protein kinase C inhibitor staurosporine
-
Sanchez-Margalet V, Lucas M, Solano F & Goberna R (1993). Sensitivity of insulin-secreting RINm5F cells to undergoing apoptosis by the protein kinase C inhibitor staurosporine. Experimental Cell Research, 209: 160-163.
-
(1993)
Experimental Cell Research
, vol.209
, pp. 160-163
-
-
Sanchez-Margalet, V.1
Lucas, M.2
Solano, F.3
Goberna, R.4
-
75
-
-
0028657016
-
Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis
-
Morgan NG, Cable HC, Newcombe NR & Williams GT (1994). Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis. Bioscience Reports, 14: 243-250.
-
(1994)
Bioscience Reports
, vol.14
, pp. 243-250
-
-
Morgan, N.G.1
Cable, H.C.2
Newcombe, N.R.3
Williams, G.T.4
-
76
-
-
0029401861
-
Differences in the expression of heat shock proteins and antioxidant enzymes between human and rodent pancreatic islets: Implications for the pathogenesis of insulin-dependent diabetes mellitus
-
Welsh N, Margulis B, Borg LAH, Wiklund HJ, Saldeen J, Flodström M, Mello MA, Andersson A, Pipeleers DG, Hellerström C & Eizirik DL (1995). Differences in the expression of heat shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus. Molecular Medicine, 1: 806-820.
-
(1995)
Molecular Medicine
, vol.1
, pp. 806-820
-
-
Welsh, N.1
Margulis, B.2
Borg, L.A.H.3
Wiklund, H.J.4
Saldeen, J.5
Flodström, M.6
Mello, M.A.7
Andersson, A.8
Pipeleers, D.G.9
Hellerström, C.10
Eizirik, D.L.11
-
77
-
-
0028179849
-
Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells
-
Ankarcrona M, Dypbukt JM, Brüne B & Nicotera P (1994). Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Experimental Cell Research, 213: 172-177.
-
(1994)
Experimental Cell Research
, vol.213
, pp. 172-177
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Brüne, B.3
Nicotera, P.4
-
78
-
-
0028889021
-
Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes
-
Mitrovic B, Ignarro LJ, Vinters HU, Akers M-A, Schmid I, Uittenbogaarts C & Merrill JE (1995). Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes. Neuroscience, 65: 531-539.
-
(1995)
Neuroscience
, vol.65
, pp. 531-539
-
-
Mitrovic, B.1
Ignarro, L.J.2
Vinters, H.U.3
Akers, M.-A.4
Schmid, I.5
Uittenbogaarts, C.6
Merrill, J.E.7
-
79
-
-
0029093781
-
Apoptotic cell death triggered by nitric oxide in pancreatic β-cells
-
Kaneto H, Fujii J, Seo HG, Suzuki K, Matsuoka T-A, Nakamura M, Tatsumi H, Yamasaki Y, Kamada T & Taniguchi N (1995). Apoptotic cell death triggered by nitric oxide in pancreatic β-cells. Diabetes, 44: 733-738.
-
(1995)
Diabetes
, vol.44
, pp. 733-738
-
-
Kaneto, H.1
Fujii, J.2
Seo, H.G.3
Suzuki, K.4
Matsuoka, T.-A.5
Nakamura, M.6
Tatsumi, H.7
Yamasaki, Y.8
Kamada, T.9
Taniguchi, N.10
-
80
-
-
0028988029
-
NOC, a nitric oxide-releasing compound, induces dose dependent apoptosis in macrophages
-
Shimaoka M, Iida T, Ohara A, Taenaka N, Mashimo T, Honda T & Yoshiya I (1995). NOC, a nitric oxide-releasing compound, induces dose dependent apoptosis in macrophages. Biochemical and Biophysical Research Communications, 209: 519-526.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.209
, pp. 519-526
-
-
Shimaoka, M.1
Iida, T.2
Ohara, A.3
Taenaka, N.4
Mashimo, T.5
Honda, T.6
Yoshiya, I.7
-
83
-
-
0026054681
-
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of β-cells
-
Eizirik DL, Sandler S, Ahnström G & Welsh M (1991). Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of β-cells. Biochemical Pharmacology, 42: 2275-2282.
-
(1991)
Biochemical Pharmacology
, vol.42
, pp. 2275-2282
-
-
Eizirik, D.L.1
Sandler, S.2
Ahnström, G.3
Welsh, M.4
-
84
-
-
0027162258
-
Induction of nitric oxide synthesis and its reactions in cultured human and rat hepatocytes stimulated with cytokines plus LPS
-
Nüssler AK, Geller DA, Sweetland MA, Di Silvio M, Billiar TR, Madariaga JB, Simmons RL & Lancaster Jr JR (1993). Induction of nitric oxide synthesis and its reactions in cultured human and rat hepatocytes stimulated with cytokines plus LPS. Biochemical and Biophysical Research Communications, 194: 826-835.
-
(1993)
Biochemical and Biophysical Research Communications
, vol.194
, pp. 826-835
-
-
Nüssler, A.K.1
Geller, D.A.2
Sweetland, M.A.3
Di Silvio, M.4
Billiar, T.R.5
Madariaga, J.B.6
Simmons, R.L.7
Lancaster Jr., J.R.8
-
85
-
-
0028181046
-
Reversibility of interleukin-1β-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase
-
Corbett JA & McDaniel ML (1994). Reversibility of interleukin-1β-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase. Biochemical Journal, 299: 719-724.
-
(1994)
Biochemical Journal
, vol.299
, pp. 719-724
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
86
-
-
0027440247
-
Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages
-
Nunoshiba T, de Rojas-Walker T, Wishnok JS, Tannenbaum SR & Demple B (1993). Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages. Proceedings of the National Academy of Sciences, USA, 90: 9993-9997.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 9993-9997
-
-
Nunoshiba, T.1
De Rojas-Walker, T.2
Wishnok, J.S.3
Tannenbaum, S.R.4
Demple, B.5
-
87
-
-
0026633029
-
Interleukin-1β increases the activity of superoxide dismutase in rat pancreatic islets
-
Borg LAH, Cagliero E, Sandler S, Welsh N & Eizirik DL (1992). Interleukin-1β increases the activity of superoxide dismutase in rat pancreatic islets. Endocrinology, 130: 2851-2857.
-
(1992)
Endocrinology
, vol.130
, pp. 2851-2857
-
-
Borg, L.A.H.1
Cagliero, E.2
Sandler, S.3
Welsh, N.4
Eizirik, D.L.5
-
88
-
-
0028170683
-
Dissociation between interleukin-1β-induced expression of mRNA for superoxide dismutase and nitric oxide synthase in insulin-producing cells
-
Bigdeli N, Niemann A, Sandler S & Eizirik DL (1994). Dissociation between interleukin-1β-induced expression of mRNA for superoxide dismutase and nitric oxide synthase in insulin-producing cells. Biochemical and Biophysical Research Communications, 203: 1542-1547.
-
(1994)
Biochemical and Biophysical Research Communications
, vol.203
, pp. 1542-1547
-
-
Bigdeli, N.1
Niemann, A.2
Sandler, S.3
Eizirik, D.L.4
-
89
-
-
0027238867
-
Genotoxic agents increase expression of growth arrest and DNA damage-inducible genes gadd 153 and gadd 45 in rat pancreatic islets
-
Eizirik DL, Bjorklund A & Cagliero E (1993). Genotoxic agents increase expression of growth arrest and DNA damage-inducible genes gadd 153 and gadd 45 in rat pancreatic islets. Diabetes, 42: 738-745.
-
(1993)
Diabetes
, vol.42
, pp. 738-745
-
-
Eizirik, D.L.1
Bjorklund, A.2
Cagliero, E.3
-
90
-
-
0026052415
-
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1β-induced impaired β-cell function
-
Margulis BA, Sandler S, Eizirik DL, Welsh N & Welsh M (1991). Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1β-induced impaired β-cell function. Diabetes, 40: 1418-1422.
-
(1991)
Diabetes
, vol.40
, pp. 1418-1422
-
-
Margulis, B.A.1
Sandler, S.2
Eizirik, D.L.3
Welsh, N.4
Welsh, M.5
-
91
-
-
0029064481
-
Heat shock induces resistance in rat pancreatic islets against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro
-
Bellman K, Wenz A, Radons J, Burkart V, Kleemann R & Kolb H (1995). Heat shock induces resistance in rat pancreatic islets against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro. Journal of Clinical Investigations, 95: 2840-2845.
-
(1995)
Journal of Clinical Investigations
, vol.95
, pp. 2840-2845
-
-
Bellman, K.1
Wenz, A.2
Radons, J.3
Burkart, V.4
Kleemann, R.5
Kolb, H.6
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