메뉴 건너뛰기




Volumn 57, Issue 4, 1997, Pages 651-658

DNA excision repair profiles of normal and leukemic human lymphocytes: Functional analysis at the single-cell level

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA;

EID: 1842290989     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (54)
  • 1
    • 0025674116 scopus 로고
    • Drug-induced DNA damage and tumor sensitivity
    • Epstein, R. J. Drug-induced DNA damage and tumor sensitivity. J. Clin. Oncol., 8: 2062-2084, 1990.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 2062-2084
    • Epstein, R.J.1
  • 4
    • 0002385099 scopus 로고
    • Alkylating agents
    • B. A. Chabner and J. M. Collins (eds.), Philadelphia: Lippincott
    • Colvin, M., and Chabner, B. A. Alkylating agents. In: B. A. Chabner and J. M. Collins (eds.), Cancer Chemotherapy Principles and Practice, pp. 276-314. Philadelphia: Lippincott, 1990.
    • (1990) Cancer Chemotherapy Principles and Practice , pp. 276-314
    • Colvin, M.1    Chabner, B.A.2
  • 5
    • 0018087684 scopus 로고
    • Oxygens in DNA are main targets for ethylnitrosourea in normal and xeroderma pigmentosum fibroblasts and fetal rat brain cells
    • Singer, B., Bodell, W. J., Cleaver, J. E., Thomas, G. H., Rajewsky, M. F., and Thon, W. Oxygens in DNA are main targets for ethylnitrosourea in normal and xeroderma pigmentosum fibroblasts and fetal rat brain cells. Nature (Lond.), 276: 85-88, 1978.
    • (1978) Nature (Lond.) , vol.276 , pp. 85-88
    • Singer, B.1    Bodell, W.J.2    Cleaver, J.E.3    Thomas, G.H.4    Rajewsky, M.F.5    Thon, W.6
  • 6
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek, D. T. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res., 231: 11-30, 1990.
    • (1990) Mutat. Res. , vol.231 , pp. 11-30
    • Beranek, D.T.1
  • 7
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase. Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA alkyltransferase. Regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res., 50: 6119-6129, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 9
    • 0026611091 scopus 로고
    • 6- alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells
    • 6- alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells. Cancer Res., 52: 2008-2011, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 2008-2011
    • Bronstein, S.M.1    Skopek, T.R.2    Swenberg, J.A.3
  • 10
    • 0026611836 scopus 로고
    • 6-methylguanine: Thymine mispairs in DNA of extracts of human cells
    • 6-methylguanine: thymine mispairs in DNA of extracts of human cells. Biochemistry, 31: 7998-8008, 1992.
    • (1992) Biochemistry , vol.31 , pp. 7998-8008
    • Sibghat-Ullah1    Day III, R.S.2
  • 11
    • 0028177052 scopus 로고
    • 6-alkylguanine in the nuclear DNA of human lymphocytes and leukaemic cells: Analysis at the single-cell level
    • 6-alkylguanine in the nuclear DNA of human lymphocytes and leukaemic cells: analysis at the single-cell level. Br. J. Cancer, 69: 698-705, 1994.
    • (1994) Br. J. Cancer , vol.69 , pp. 698-705
    • Thomale, J.1    Seiler, F.2    Müller, M.R.3    Seeber, S.4    Rajewsky, M.F.5
  • 14
    • 0025924488 scopus 로고
    • 6-benzylguanine analogues on the sensitivity of human tumor cells to the cytotoxic effect of alkylating agents
    • 6-benzylguanine analogues on the sensitivity of human tumor cells to the cytotoxic effect of alkylating agents. Cancer Res., 51: 3367-3372, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3367-3372
    • Dolan, M.E.1    Mitchell, R.B.2    Mummert, C.3    Moschel, R.C.4    Pegg, A.E.5
  • 15
    • 0027434870 scopus 로고
    • 6-benzylguanine
    • 6-benzylguanine. Biochemistry, 32: 11998-12006, 1993.
    • (1993) Biochemistry , vol.32 , pp. 11998-12006
    • Pegg, A.E.1
  • 16
    • 0027339636 scopus 로고
    • 6-benzylguanine and 1.3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograph completely resistant to BCNU alone
    • 6-benzylguanine and 1.3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograph completely resistant to BCNU alone. Biochem. Pharmacol., 45: 483-491, 1993.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 483-491
    • Gerson, S.L.1    Zborowska, E.2    Norton, K.3    Gordon, N.H.4    Willson, J.K.5
  • 17
    • 0027380294 scopus 로고
    • 6-alkylation products in individual cells by monoclonal antibodies and digital imaging of intensified nuclear fluorescence
    • 6-alkylation products in individual cells by monoclonal antibodies and digital imaging of intensified nuclear fluorescence. Carcinogenesis (Lond.), 9: 1907-1913, 1993.
    • (1993) Carcinogenesis (Lond.) , vol.9 , pp. 1907-1913
    • Seiler, F.1    Kirstein, U.2    Eberle, G.3    Hochleitner, K.4    Rajewsky, M.F.5
  • 19
    • 0028822646 scopus 로고
    • Overexpression of the XPA repair gene increases resistance to ultraviolet radiation in human cells by selective repair of DNA damage
    • Cleaver, J. E., Charles, W. C., McDowell, M. L., Sadinsky, W. J., and Mitchell, D. L. Overexpression of the XPA repair gene increases resistance to ultraviolet radiation in human cells by selective repair of DNA damage. Cancer Res., 55: 6152-6160, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 6152-6160
    • Cleaver, J.E.1    Charles, W.C.2    McDowell, M.L.3    Sadinsky, W.J.4    Mitchell, D.L.5
  • 20
    • 0030041960 scopus 로고    scopus 로고
    • Repair-deficient 3-methlyadenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing
    • Engelward, B. P., Dreslin, A., Christensen, J., Huszar, D., Kurahara, C., and Samson, L. Repair-deficient 3-methlyadenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. EMBO J., 15: 945-952, 1996.
    • (1996) EMBO J. , vol.15 , pp. 945-952
    • Engelward, B.P.1    Dreslin, A.2    Christensen, J.3    Huszar, D.4    Kurahara, C.5    Samson, L.6
  • 21
    • 0029144513 scopus 로고
    • Repair of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea-induced damage by mammalian cell extracts
    • Cappelli, E., Redaelli, A., Rivano, M. E., Abbondandolo, A., and Frosina, G. Repair of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea-induced damage by mammalian cell extracts. Carcinogenesis (Lond.), 16: 2267-2270, 1995.
    • (1995) Carcinogenesis (Lond.) , vol.16 , pp. 2267-2270
    • Cappelli, E.1    Redaelli, A.2    Rivano, M.E.3    Abbondandolo, A.4    Frosina, G.5
  • 25
    • 0028964370 scopus 로고
    • Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance
    • Bramson, J., McQuillan, A., Aubin, R., Alaoui-Jamali, M., and Batist, G. Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance. Mutat. Res., 336: 269-278, 1995.
    • (1995) Mutat. Res. , vol.336 , pp. 269-278
    • Bramson, J.1    McQuillan, A.2    Aubin, R.3    Alaoui-Jamali, M.4    Batist, G.5
  • 26
    • 0026465075 scopus 로고
    • Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells
    • Ibeanu, G., Hartenstein, B., Dunn, W. C., Chang, L. Y., Hofmann, E., Coquerelle, T., Mitra, S., and Kaina, B. Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells. Carcinogenesis (Lond.), 13: 1989-1995, 1992.
    • (1992) Carcinogenesis (Lond.) , vol.13 , pp. 1989-1995
    • Ibeanu, G.1    Hartenstein, B.2    Dunn, W.C.3    Chang, L.Y.4    Hofmann, E.5    Coquerelle, T.6    Mitra, S.7    Kaina, B.8
  • 27
    • 0028596574 scopus 로고
    • A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress
    • Walker, L. J., Craig, B. E., Harris, A. L., and Hickson, I. D. A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Res., 22: 4884-4889, 1995.
    • (1995) Nucleic Acids Res. , vol.22 , pp. 4884-4889
    • Walker, L.J.1    Craig, B.E.2    Harris, A.L.3    Hickson, I.D.4
  • 29
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N. P., Tice, R. R., Stephens, R. E., and Schneider, E. L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175: 184-191, 1988.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    Tice, R.R.2    Stephens, R.E.3    Schneider, E.L.4
  • 30
    • 0028918375 scopus 로고
    • The cornet assay: A comprehensive review
    • Fairbairn, D. W., Olive, P. L., and O'Neill, K. L. The cornet assay: a comprehensive review. Mutat. Res., 339: 37-59, 1995.
    • (1995) Mutat. Res. , vol.339 , pp. 37-59
    • Fairbairn, D.W.1    Olive, P.L.2    O'Neill, K.L.3
  • 31
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the comet assay
    • Olive, P. L., Banath, J. P., and Durand, R. E. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the comet assay. Radiat. Res., 122: 86-94, 1990.
    • (1990) Radiat. Res. , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 32
    • 0026738581 scopus 로고
    • Single cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells
    • Gedik, C. M., Ewens, S. W. B., and Collins, A. R. Single cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells. Int. J. Radiat. Biol., 62: 313-320, 1992.
    • (1992) Int. J. Radiat. Biol. , vol.62 , pp. 313-320
    • Gedik, C.M.1    Ewens, S.W.B.2    Collins, A.R.3
  • 33
    • 0026501421 scopus 로고
    • UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: A potential diagnostic technique
    • Green, M. H. L., Lowe, J. E., Harkourt, S. A., Akinluyi, P., Rowe, T., Cole, J., Anstey, A. V., and Arlett, C. F. UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique. Mutat. Res., 273: 137-144, 1992.
    • (1992) Mutat. Res. , vol.273 , pp. 137-144
    • Green, M.H.L.1    Lowe, J.E.2    Harkourt, S.A.3    Akinluyi, P.4    Rowe, T.5    Cole, J.6    Anstey, A.V.7    Arlett, C.F.8
  • 34
    • 0027994402 scopus 로고
    • A single-cell gel-electrophoresis technique for the detection of DNA damage induced by ACNU, an alkylating agent or irradiation in murine glioma cell lines
    • Hara, A., Zhang, W., Kohayashi, H., Niikawa, S., Sakai, N., and Yamada, H. A single-cell gel-electrophoresis technique for the detection of DNA damage induced by ACNU, an alkylating agent or irradiation in murine glioma cell lines. Neurol. Res., 16: 234-240, 1994.
    • (1994) Neurol. Res. , vol.16 , pp. 234-240
    • Hara, A.1    Zhang, W.2    Kohayashi, H.3    Niikawa, S.4    Sakai, N.5    Yamada, H.6
  • 35
    • 0015362491 scopus 로고
    • 14C in the fetal and adult rat
    • 14C in the fetal and adult rat. Cancer Res., 32: 1501-1505, 1972.
    • (1972) Cancer Res. , vol.32 , pp. 1501-1505
    • Goth, R.1    Rajewsky, M.F.2
  • 37
    • 0028596468 scopus 로고
    • Induction and mechanism of DNA single- And double- strand breaks by tetracycline/Cu(II) in the absence of light
    • Buschfort, C., and Wirte, I. Induction and mechanism of DNA single- and double- strand breaks by tetracycline/Cu(II) in the absence of light. Carcinogenesis (Lond.), 15: 2927-2930, 1994.
    • (1994) Carcinogenesis (Lond.) , vol.15 , pp. 2927-2930
    • Buschfort, C.1    Wirte, I.2
  • 39
    • 0021843514 scopus 로고
    • A new approach to the study of the base-excision repair pathway using methoxyamine
    • Liuzzi, M., and Talpaert-Borle, M. A new approach to the study of the base-excision repair pathway using methoxyamine. J. Biol. Chem., 260: 5252-5258, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 5252-5258
    • Liuzzi, M.1    Talpaert-Borle, M.2
  • 40
    • 0022273524 scopus 로고
    • Quantitation and visualization of alkyl-deoxynucleosides in the DNA of mammalian cells by monoclonal antibodies
    • Adamkiewicz, J., Eberle, G., Huh, N., Nehls, P., and Rajewsky, M. F. Quantitation and visualization of alkyl-deoxynucleosides in the DNA of mammalian cells by monoclonal antibodies. Environ. Health Perspect., 62: 49-55, 1985.
    • (1985) Environ. Health Perspect. , vol.62 , pp. 49-55
    • Adamkiewicz, J.1    Eberle, G.2    Huh, N.3    Nehls, P.4    Rajewsky, M.F.5
  • 41
    • 0004339248 scopus 로고    scopus 로고
    • Monoclonal antibody- Based quantification and repair analysis of specific alkylation products in DNA
    • G. P. Pfeiffer (ed.), New York: Plenum Press
    • Thomale, J., Engelbergs, J., Seiler, F., and Rajewsky, M. F. Monoclonal antibody- based quantification and repair analysis of specific alkylation products in DNA. In: G. P. Pfeiffer (ed.), Technologies for the Detection of DNA Damage and Mutations, pp. 87-102. New York: Plenum Press, 1996.
    • (1996) Technologies for the Detection of DNA Damage and Mutations , pp. 87-102
    • Thomale, J.1    Engelbergs, J.2    Seiler, F.3    Rajewsky, M.F.4
  • 42
    • 0028865604 scopus 로고
    • The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay)
    • Speit, G., and Hartmann, A. The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay). Mutagenesis, 10: 555-559, 1995.
    • (1995) Mutagenesis , vol.10 , pp. 555-559
    • Speit, G.1    Hartmann, A.2
  • 43
    • 0029864861 scopus 로고    scopus 로고
    • Analysis of DNA alkylation and repair in mammalian cells by the comet assay
    • Fortini, P., Raspaglio, G., Falchi, M., and Dogliotti, E. Analysis of DNA alkylation and repair in mammalian cells by the comet assay. Mutagenesis, 11: 169-175, 1996.
    • (1996) Mutagenesis , vol.11 , pp. 169-175
    • Fortini, P.1    Raspaglio, G.2    Falchi, M.3    Dogliotti, E.4
  • 44
    • 0029557172 scopus 로고
    • Determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis "comet" assay
    • Malcolmson, A. M., Davies, G., Hanson, J. A, Deeley, J. O. T., Gaffney, C. C., McGregor, A. D., and Kerby, I. J. Determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis "comet" assay. Eur. J. Cancer, 33A: 2320-2323, 1995.
    • (1995) Eur. J. Cancer , vol.33 A , pp. 2320-2323
    • Malcolmson, A.M.1    Davies, G.2    Hanson, J.A.3    Deeley, J.O.T.4    Gaffney, C.C.5    McGregor, A.D.6    Kerby, I.J.7
  • 45
    • 0023159814 scopus 로고
    • 4- ethylthymine and the ethylphosphotriester dTp(Et)dT are highly persistent DNA modifications in slowly dividing tissues of the ethylnitrosourea-treated rat
    • 4- ethylthymine and the ethylphosphotriester dTp(Et)dT are highly persistent DNA modifications in slowly dividing tissues of the ethylnitrosourea-treated rat. Carcinogenesis (Lond.), 8: 751-757, 1987.
    • (1987) Carcinogenesis (Lond.) , vol.8 , pp. 751-757
    • Den Engelse, L.1    De Graaf, A.2    De Brij, R.-J.3    Menkveid, G.J.4
  • 46
    • 0028932764 scopus 로고
    • 3-Methyladenine and 7-methylguanine exhibit no preferential removal from the transcribed strand of the dehydrofolate reductase gene in Chinese hamster ovarian B11 cells
    • Wang, W., Sitaram, A., and Scicchitano, D. A. 3-Methyladenine and 7-methylguanine exhibit no preferential removal from the transcribed strand of the dehydrofolate reductase gene in Chinese hamster ovarian B11 cells. Biochemistry, 34: 1798-1804, 1995.
    • (1995) Biochemistry , vol.34 , pp. 1798-1804
    • Wang, W.1    Sitaram, A.2    Scicchitano, D.A.3
  • 47
    • 0028057718 scopus 로고
    • 6-ethylguanine in transcribed and non- Transcribed genes in rat
    • 6-ethylguanine in transcribed and non- transcribed genes in rat. J. Biol. Chem., 269(3)): 1681-1686, 1994.
    • (1994) J. Biol. Chem. , vol.269 , Issue.3 , pp. 1681-1686
    • Thomale, J.1    Hochleitner, K.2    Rajewsky, M.F.3
  • 51
    • 0028918746 scopus 로고
    • 6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate. N-(2-hydroxyethyl)-N-nitrosourea or N-ethyl-N-nitrosourea
    • 6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate. N-(2-hydroxyethyl)-N-nitrosourea or N-ethyl-N-nitrosourea. Cancer Res., 55: 1875- 1882, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1875-1882
    • Jansen, J.G.1    Vrieling, H.2    Van Teijlingen, C.M.M.3    Mohn, G.R.4    Tates, A.D.5    Van Zeeland, A.A.6
  • 53
    • 0026069790 scopus 로고
    • Processing in vitro of abasic site reacted with methoxyamine: A new assay for the detection of abasic sites in vivo
    • Rosa, S. Fortini, P., Karran, P., Bigniami, M., and Dogliotti, E. Processing in vitro of abasic site reacted with methoxyamine: a new assay for the detection of abasic sites in vivo. Nucleic Acids Res., 19: 5569-5574, 1991.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5569-5574
    • Rosa, S.1    Fortini, P.2    Karran, P.3    Bigniami, M.4    Dogliotti, E.5
  • 54
    • 0028946062 scopus 로고
    • Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns of ERCC1 and ERCC2
    • Dabholkar, M. D., Berger, M. S., Vionnet, J. A., Egwuagu, C., Silber, J. R., Yu, J. J., and Reed, E. Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns of ERCC1 and ERCC2. Cancer Res., 55: 1261-1266, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1261-1266
    • Dabholkar, M.D.1    Berger, M.S.2    Vionnet, J.A.3    Egwuagu, C.4    Silber, J.R.5    Yu, J.J.6    Reed, E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.