Apoptosis in proliferative vitreoretinal disorders: Possible involvement of TGF-β-induced RPE cell apoptosis

Experimental Eye Research

Volumn 65, Issue 3, 1997, Pages 365-378

  Esser, Peter ^c   Heimann, Klaus ^d   Bartz Schmidt, Karl Ulrich ^d   Fontana, Adriano ^a   Schraermeyer, Ulrich ^d   Thumann, Gabriele ^d   Weller, Michael ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^d NONE

Author keywords

Apoptosis; Programmed cell death; Proliferative diabetic retinopathy; Proliferative vitreoretinopathy; Retinal pigment epithelium; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; DIABETIC RETINOPATHY; GROWTH REGULATION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; PATHOGENESIS; PRIORITY JOURNAL; RETINA CELL; VITREORETINOPATHY;

EID: 0030874743     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1997.0341     Document Type: Article

References (59)

1. Assoian, R. K., Fleurdelys, B. E., Stevenson, H. C., Miller, P. J., Madtes, D. K., Raines, E. W., Ross, R. and Sporn, M. B. (1987). Expression and secretion of type beta transforming growth factor by activated human macrophages. Proc. Natl. Acad. Sci. U.S.A. 84, 6020-4.
2. Barry, M. A., Behnke, C. A. and Eastman, A. (1990). Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem. Pharmacol. 40, 2353-62.
3. Chang, C. J., Lai, W. W., Edward, D. P. and Tso, M. O. M. (1995). Apoptotic photoreceptor cell death after traumatic retinal detachment in humans. Arch. Ophthalmol. 113, 880-6.
4. Connor, T. B., Jr., Roberts, A. B., Sporn, M. B., Danielpour, D., Dart, L. L., Michels, R. G., de Bustros, S., Enger, C., Kato, H., Lansing, M., Hayashi, H. and Glaser, B. M. (1989). Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye. J. Clin. Invest. 83, 1661-6.
5. 3 by glioblastoma cells, astrocytes and microglia. J. Immunol. 148, 1404-10.
6. Cook, B., Lewis, G. P., Fisher, S. K. and Adler, R. (1995). Apoptotic photoreceptor degeneration in experimental retinal detachment. Invest. Ophthalmol. Vis. Sci. 36, 990-6.
7. Dallas, S. L., Miyazono, K., Skerry, T. M., Mundy, G. R. and Bonewald, L. F. (1995). Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein. J. Cell Biol. 131, 539-49.
8. Esser, P., Heimann, K., Abts, H., Fontana, A. and Weller, M. (1995). CD95 (Fas/APO-1) antibody-mediated apoptosis of human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 213, 1026-34.
9. Esser, P., Heimann, K. and Wiedemann, P. (1993). Macrophages in proliferative vitreoretinopathy and proliferative diabetic retinopathy, differentiation of subpopulations. Br. J. Ophthalmol. 77, 731-3.
10. Esser, P., Weller, M., Bresgen, M., Heimann, K. and Wiedemann, P. (1992). The effects of basic fibroblast growth factor on bovine retinal pigment epithelium in vitro. Ger. J. Ophthalmol. 1, 58-61.
11. Flanders, K. C., Thompson, N. L., Cissel, D. S., Van Obberghen-Schilling, E., Baker, C. C., Kass, M. E., Ellingsworth, L. R., Roberts, A. B. and Sporn, M. B. (1989). Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes. J. Cell Biol. 108, 653-60.
12. Gabrielian, K., Osusky, R., Sippy, B. D., Ryan, S. J. and Hinton, D. R. (1994). Effect of TGF-β on interferon-γ-induced HLA-DR expression in human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 35, 4253-9.
13. Gaudric, A., Glacet Bernard A., Clement G., Falquerho, L., Barritault, D. and Coscas, G. (1990). Transforming growth factor beta in the vitreous of patients with epiretinal proliferation. Ophthalmologie 4, 51-2.
14. Gavrieli, Y., Sherman, Y. and Ben-Sasson, S. A. (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
15. Gopalakrishna, P. and Khar, A. (1995). Comet assay to measure DNA damage in apoptotic cells. J. Biochem. Biophys. Methods 30, 69-73.
16. Gregory, C. Y. and Bird, A. C. (1995). Cell loss in retinal dystrophies by apoptosis - death by informed consent! Br. J. Ophthalmol. 79, 186-90.
17. Heimann, K. and Wiedemann, P. (1989). Cologne classification of proliferative vitreoretinopathy. In: (Heimann, K. and Wiedemann, P. Eds) Proliferative vitreoretinopathy. Pp 148-9. Kaden: Heidelberg.
18. Hiscott, P. S., Grierson, I. and McLeod, D. (1985). Natural history of fibrocellular epiretinal membranes: a quantitative, autoradiographic, and immunohistochemical study. Br. J. Ophthalmol. 69, 810-23.
19. Hiscott, P. S., Grierson, I., Trombetta, C. J., Rahi, C. J., Marshall, A. H. S. and McLeod, D. (1984). Retinal and epiretinal glia - an immunohistochemical study. Br. J. Ophthalmol. 68, 698-707.
20. Immonen, I. J. R., Salonen, E. M., Vaheri, A. I. and Laatikainen, L. T. (1988). Plasmin in subretinal fluid. Acta Ophthalmol. 66, 647-51.
21. Kerr, J. F. R., Wyllie, A. H. and Currie, A. R. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-57.
22. Lang, R., Lustig, M., Francois, F., Sellinger, M. and Plesken, H. (1994). Apoptosis during macrophage-dependent ocular tissue remodelling. Development 120, 3395-403.
23. Leschey, K. H., Hackett, S. F., Singer, J. H. and Campochiaro, P. A. (1990). Growth factor responsiveness of human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 31, 839-46.
24. Li, W. C., Kuszak, J. R., Dunn, K., Wang, R. R., Ma, W., Wang, G. M., Spector, A., Leib, M., Cotliar, A. M. and Weiss, M. (1995). Lens epithelial apoptosis appears to be a common cellular basis for non-conginental cataract development in humans and animals. J. Cell Biol. 130, 169-81.
25. Limb, G. A., Little, B. C., Meager, A., Ogilvie, J. A., Wolstencroft, R. A., Franks, W. A., Chignell, A. H. and Dumonde, D. C. (1991). Cytokines in proliferative vitreoretinopathy. Eye 5, 686-93.
26. Lolley, R. N., Rong, H. and Craft, C. M. (1994). Linkage of photoreceptor degeneration by apoptosis with inherited defect in phototransduction. Invest. Ophthalmol. Vis. Sci. 35, 358-62.
27. Lowry, O. H., Rosebrough, B. J., Farr, A. L. and Randall, R. J. (1951). Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-75.
28. Lutty, G. A., Merges, C., Threlkeld, A. B., Crone, S. and McLeod, D. S. (1993). Heterogeneity in localization of isoforms of TGF-beta in human retina, vitreous, and choroid. Invest. Ophthalmol Vis. Sci. 34, 477-487.
29. Lyons, R. M., Keski-Oja, J. and Moses, H. L. (1990). Mechanisms of activation of latent recombinant transforming growth factor-β1 by plasmin. J. Cell Biol. 110, 1361-7.
30. Machemer, R., Aaberg, T. M., Freeman, H. M., Irvine, A. R., Lean, J. S. and Michels, R. M. (1991). An updated classification of retinal detachment with proliferative vitreoretinopathy. Am. J. Ophthalmol. 112, 159-65.
31. Machemer, R. and Laqua, H. (1975). Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation). Am. J. Ophthalmol. 80, 1-23.
32. Martin, S. J. and Green, D. R. (1995). Apoptosis and cancer: the failure of controls on cell death and cell survival. Crit. Rev. Oncol. Hematol. 18, 137-53.
33. Melino, G., Annicchiarico-Petruzzelli, M. and Piredda, L. (1994). Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol. Cell Biol. 154, 6584-96.
34. Oberhammer, F., Wilson, J. W., Dive, C., Morris, I. D., Hickman, J. A., Wakeling, A. E., Walker, P. R. and Sikorska, M. (1993). Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12, 3679-84.
35. Papermaster, D. S. and Windle, J. (1995). Death at an early age. Apoptosis in inherited retinal degenerations. Invest. Ophthalmol. Vis. Sci. 36, 977-83.
36. Pasquale, L. R., Dorman Pease, M. E., Lutty, G. A., Quigley, H. A. and Jampel, H. D. (1993). Immunolocalization of TGF-beta 1, TGF-beta 2, and TGF-beta 3 in the anterior segment of the human eye. Invest. Ophthalmol. Vis. Sci. 34, 23-30.
37. Penfold, P. L. and Provis, J. M. (1986). Cell death in the development of the human retina: phagocytosis of pyknotic and apoptotic bodies by retinal cells. Graefes. Arch. Clin. Exp. Ophthalmol. 224, 549-53.
38. Quigley, H. A., Nickells, R. W., Kerrigan, L. A., Pease, M. E., Thibault, D. J. and Zack, D. J. (1994). Ganglion cell death in experimental monkey glaucoma and axotomy occurs by apoptosis. Invest. Ophthalmol. Vis. Sci. 35, 2083.
39. Reed, J. C. (1994). Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124, 1-6.
40. Savill, J., Hogg, N., Ren, Y. and Haslett, C. (1992). Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J. Clin. Invest. 90, 1513-22.
41. Schulte-Frohlinde, D., Simic, M. G. and Gorner, H. (1990). Laser-induced strand break formation in DNA and polynucleotides. Photochem. Photobiol. 52, 1137-51.
42. Sellins, K. S. and Cohen, J. J. (1991). Hyperthermia induces apoptosis in thymocytes. Radiat. Res. 126, 88-95.
43. Tanihara, H., Yoshida, M., Matsumoto, M. and Yoshimura, N. (1993). Identification of transforming growth factor-β expressed in cultured human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 34, 413-19.
44. Thompson, C. B. (1995). Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-62.
45. Truong, L. D., Kadmon, D., McCune, B. K., Flanders, K. C., Scardino, P. T. and Thompson, T. C. (1993). Association of transforming growth factor β1 with prostate cancer. Hum. Pathol. 24, 4-9.
46. Tso, M. O., Zhang, C., Abler, A. S., Chang, C. J., Wong, F., Chang, G. Q. and Lam, T. T. (1994). Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats. Invest. Ophthalmol. Vis. Sci. 35, 2693-9.
47. Weller, M., Bresgen, M., Heimann, K. and Wiedemann, P. (1990a). Blood coagulation factor XIII contributes to the development of periretinal membranes. Acta Ophthalmol. 68, 246-52.
48. Weller, M., Constam, D. B., Malipiero, U. and Fontana, A. (1994a). Transforming growth factor-β2 induces apoptosis of murine T cell clones without downregulating bcl-2 mRNA expression. Eur. J. Immunol. 24, 1293-300.
49. Weller, M., Esser, P., Bresgen, M., Heimann, K. and Wiedemann, P. (1992). Thrombospondin: a new attachment protein in preretinal traction membranes. Eur. J. Ophthalmol. 2, 10-14.
50. Weller, M., Esser, P., Heimann, K. and Wiedemann, P. (1991a). Mononuclear phagocytes in proliferative vitreoretinopathie (PVR). A specific role of microglial cells in non-traumatic disease? Eur. J. Ophthalmol. 1, 161-6.
51. Weller, M., Esser, P., Heimann, K. and Wiedemann, P. (1991b). Retinal microglia: a new cell in idiopathic proliferative vitreoretinopathy? Exp. Eye Res. 53, 275-81.
52. Weller, M. and Fontana, A. (1995a). The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-β, T cell apoptosis and the immune privilege of the brain. Brain Res. Rev. 21, 128-51.
53. Weller, M., Frei, K., Groscurth, P., Krammer, P. H., Yonekawa, Y. and Fontana, A. (1994b). Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. J. Clin. Invest. 94, 954-64.
54. Weller, M., Heimann, K. and Wiedemann, P. (1988a). Immunochemical studies of epiretinal membranes using APAAP complexes. Evidence for macrophage involvement in traumatic proliferative vitreoretinopathy. Int. Ophthalmol. 11, 181-6.
55. Weller, M., Heimann, K. and Wiedemann, P. (1988b). Demonstration of mononuclear phagocytes in a human epiretinal membrane using a monoclonal anti-human macrophage antibody. Graefes. Arch. Clin. Exp. Ophthalmol. 226, 252-4.
56. Weller, M., Malipiero, U. V., Aguzzi, A., Reed, J. C. and Fontana, A. (1995b). Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. J. Clin. Invest. 95, 2633-4.
57. 2: modulation by the phosphatase inhibitors, okadaic acid and calyculin A. Exp. Cell Res. 221, 395-403.
58. Weller, M., Wiedemann, P. and Heimann, K. (1990b). Proliferative vitreoretinopathy - is it anything more than wound healing at the wrong place? Int. Ophthalmol. 14, 105-17.
59. Yamashita, H., Hori, S. and Masuda, K. (1986). Population and proportion of component cells in preretinal membranes. Jpn. J. Ophthalmol. 30, 269-81.