-
1
-
-
0030888122
-
Naturally occurring primary deficiencies of the immune system
-
Fischer A, et al. Naturally occurring primary deficiencies of the immune system. Annu Rev Immunol 1997;15:93-124.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 93-124
-
-
Fischer, A.1
-
2
-
-
0035752146
-
Cytokines and immunodeficiency diseases
-
Leonard WJ. Cytokines and immunodeficiency diseases. Nat Rev Immunol 2001;1:200-208.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 200-208
-
-
Leonard, W.J.1
-
3
-
-
0036246445
-
Primary cellular immunodeficiencies
-
Buckley RH. Primary cellular immunodeficiencies. J Allergy Clin Immunol 2002;109:747-757.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 747-757
-
-
Buckley, R.H.1
-
4
-
-
2542461255
-
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution
-
Buckley RH. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. Annu Rev Immunol 2004;22:625-655.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 625-655
-
-
Buckley, R.H.1
-
5
-
-
0036464666
-
Hematopoietic stem cell transplantation for severe combined immunodeficiency in the neonatal period leads to superior thymic output and improved survival
-
Myers LA, Patel DD, Puck JM, Buckley RH. Hematopoietic stem cell transplantation for severe combined immunodeficiency in the neonatal period leads to superior thymic output and improved survival. Blood 2002;99:872-878.
-
(2002)
Blood
, vol.99
, pp. 872-878
-
-
Myers, L.A.1
Patel, D.D.2
Puck, J.M.3
Buckley, R.H.4
-
6
-
-
0842327458
-
Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: Huge review
-
Kalman L, et al. Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: huge review. Genet Med 2004;6:16-26.
-
(2004)
Genet Med
, vol.6
, pp. 16-26
-
-
Kalman, L.1
-
7
-
-
0029126218
-
Adenosine deaminase deficiency: Molecular basis and recent developments
-
Hirschhorn R. Adenosine deaminase deficiency: molecular basis and recent developments. Clin Immunol Immunopathol 1995;76:S219-S227.
-
(1995)
Clin Immunol Immunopathol
, vol.76
-
-
Hirschhorn, R.1
-
8
-
-
0021833639
-
Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency
-
Shearer WT, et al. Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency. N Engl J Med 1985;312:1151-1159.
-
(1985)
N Engl J Med
, vol.312
, pp. 1151-1159
-
-
Shearer, W.T.1
-
9
-
-
0023442485
-
Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-q13
-
de Saint Basile G, et al. Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-q13. Proc Natl Acad Sci USA 1987;84:7576-7579.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7576-7579
-
-
De Saint Basile, G.1
-
10
-
-
0027403374
-
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
-
Noguchi M, et al. Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 1993;73:147-157.
-
(1993)
Cell
, vol.73
, pp. 147-157
-
-
Noguchi, M.1
-
11
-
-
0025599933
-
Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes
-
Chatila T, et al. Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes. Proc Natl Acad Sci USA 1990;87:10033-10037.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 10033-10037
-
-
Chatila, T.1
-
12
-
-
0025297840
-
Severe combined immunodeficiency due to a specific defect in the production of interleukin-2
-
Weinberg K, Parkman R. Severe combined immunodeficiency due to a specific defect in the production of interleukin-2. N Engl J Med 1990;322:1718-1723.
-
(1990)
N Engl J Med
, vol.322
, pp. 1718-1723
-
-
Weinberg, K.1
Parkman, R.2
-
13
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
Schorle H, Holtschke T, Hunig T, Schimpl A, Horak I. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 1991;15:621-624.
-
(1991)
Nature
, vol.15
, pp. 621-624
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
14
-
-
0027731604
-
Sharing of interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
-
Kondo M, et al. Sharing of interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 1993;262:1874-1877.
-
(1993)
Science
, vol.262
, pp. 1874-1877
-
-
Kondo, M.1
-
15
-
-
0027751556
-
Interleukin-2 receptor gamma chain: A functional component of the interleukin-7 receptor
-
Noguchi M, et al. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science 1993;262:1877-1880.
-
(1993)
Science
, vol.262
, pp. 1877-1880
-
-
Noguchi, M.1
-
16
-
-
0027787877
-
Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor
-
Russell SM, et al. Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science 1993;262:1880-1883.
-
(1993)
Science
, vol.262
, pp. 1880-1883
-
-
Russell, S.M.1
-
17
-
-
0028171065
-
Interaction of IL-2Rβ and γc chains with Jak1 and Jak3. Implications for XSCID and XCID
-
Russell SM, et al. Interaction of IL-2Rβ and γc chains with Jak1 and Jak3. Implications for XSCID and XCID. Science 1994;266:1042-1045.
-
(1994)
Science
, vol.266
, pp. 1042-1045
-
-
Russell, S.M.1
-
18
-
-
0028221433
-
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15
-
Giri JG, et al. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 1994;13:2822-2830.
-
(1994)
EMBO J
, vol.13
, pp. 2822-2830
-
-
Giri, J.G.1
-
19
-
-
0028814556
-
Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex
-
Kimura Y, et al. Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex. Int Immunol 1995;7:115-120.
-
(1995)
Int Immunol
, vol.7
, pp. 115-120
-
-
Kimura, Y.1
-
20
-
-
0035400054
-
Cutting edge: The common gamma-chain is an indispensable subunit of the IL-21 receptor complex
-
Asao H, et al. Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol 2001;167:1-5.
-
(2001)
J Immunol
, vol.167
, pp. 1-5
-
-
Asao, H.1
-
21
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki K, et al. A critical role for IL-21 in regulating immunoglobulin production. Science 2002;298:1630-1634.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
-
22
-
-
0037119351
-
Cytokine and cytokine receptor pleiotropy and redundancy
-
Ozaki K, Leonard WJ. Cytokine and cytokine receptor pleiotropy and redundancy. J Biol Chem 2002;277:29355-29358.
-
(2002)
J Biol Chem
, vol.277
, pp. 29355-29358
-
-
Ozaki, K.1
Leonard, W.J.2
-
23
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain
-
Cao X, et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 1995;2:223-238.
-
(1995)
Immunity
, vol.2
, pp. 223-238
-
-
Cao, X.1
-
24
-
-
0028878330
-
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
-
Disanto JP, Muller W, Guy-Grand D, Fischer A, Rajewsky K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc Natl Acad Sci USA 1995;92:377-381.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 377-381
-
-
Disanto, J.P.1
Muller, W.2
Guy-Grand, D.3
Fischer, A.4
Rajewsky, K.5
-
25
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka T, et al. Defective lymphoid development in mice lacking Jak3. Science 1995;270:800-802.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
-
26
-
-
0029550822
-
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
-
Park SY, et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 1995;3:771-782.
-
(1995)
Immunity
, vol.3
, pp. 771-782
-
-
Park, S.Y.1
-
27
-
-
0034979957
-
Impaired interferon gamma-mediated immunity and susceptibility to mycobacterial infection in childhood
-
Remus N, et al. Impaired interferon gamma-mediated immunity and susceptibility to mycobacterial infection in childhood. Pediatr Res 2001;50:8-13.
-
(2001)
Pediatr Res
, vol.50
, pp. 8-13
-
-
Remus, N.1
-
28
-
-
0030455878
-
Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection
-
Jouanguy E, et al. Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N Engl J Med 1996;335:1956-1961.
-
(1996)
N Engl J Med
, vol.335
, pp. 1956-1961
-
-
Jouanguy, E.1
-
29
-
-
0030467174
-
A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection
-
Newport MJ, et al. A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. N Engl J Med 1996;335:1941-1949.
-
(1996)
N Engl J Med
, vol.335
, pp. 1941-1949
-
-
Newport, M.J.1
-
30
-
-
0033967256
-
Partial interferon-gamma receptor signaling chain deficiency in a patient with bacille Calmette-Guerin and Mycobacterium abscessus infection
-
Doffinger R, et al. Partial interferon-gamma receptor signaling chain deficiency in a patient with bacille Calmette-Guerin and Mycobacterium abscessus infection. J Infect Dis 2000;181:379-384.
-
(2000)
J Infect Dis
, vol.181
, pp. 379-384
-
-
Doffinger, R.1
-
31
-
-
0035854542
-
Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
-
Dupuis S, et al. Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 2001;293:300-303.
-
(2001)
Science
, vol.293
, pp. 300-303
-
-
Dupuis, S.1
-
32
-
-
0031919849
-
Jaks and STATs: Biological implications
-
Leonard WJ, O'Shea JJ. Jaks and STATs: biological implications. Annu Rev Immunol 1998;16:293-322.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
33
-
-
0038539290
-
Of JAKs, STATs, blind watchmakers, jeeps and trains
-
Kerr IM, Costa-Pereira AP, Lillemeier BF, Strobl B. Of JAKs, STATs, blind watchmakers, jeeps and trains. FEBS Lett 2003;546:1-5.
-
(2003)
FEBS Lett
, vol.546
, pp. 1-5
-
-
Kerr, I.M.1
Costa-Pereira, A.P.2
Lillemeier, B.F.3
Strobl, B.4
-
34
-
-
0036885067
-
The lineage decisions of helper T cells
-
Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol 2002;2:933-944.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
35
-
-
18244428735
-
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
-
Altare F, et al. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency. Science 1998;280:1432-1435.
-
(1998)
Science
, vol.280
, pp. 1432-1435
-
-
Altare, F.1
-
36
-
-
0032535370
-
Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection
-
Altare F, et al. Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection. J Clin Invest 1998;102:2035-2040.
-
(1998)
J Clin Invest
, vol.102
, pp. 2035-2040
-
-
Altare, F.1
-
37
-
-
0032577295
-
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
-
de Jong R, et al. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. Science 1998;280:1435-1438.
-
(1998)
Science
, vol.280
, pp. 1435-1438
-
-
De Jong, R.1
-
38
-
-
0026684134
-
Cloning of the gamma chain of the human IL-2 receptor
-
Takeshita T, et al. Cloning of the gamma chain of the human IL-2 receptor. Science 1992;257:379-382.
-
(1992)
Science
, vol.257
, pp. 379-382
-
-
Takeshita, T.1
-
39
-
-
0020409664
-
A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor
-
Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature 1982;300:267-269.
-
(1982)
Nature
, vol.300
, pp. 267-269
-
-
Leonard, W.J.1
Depper, J.M.2
Uchiyama, T.3
Smith, K.A.4
Waldmann, T.A.5
Greene, W.C.6
-
40
-
-
0021193219
-
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
-
Leonard WJ, et al. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature 1984;311:626-631.
-
(1984)
Nature
, vol.311
, pp. 626-631
-
-
Leonard, W.J.1
-
41
-
-
0021123385
-
Molecular cloning of cDNA encoding human interleukin-2 receptor
-
Nikaido T, et al. Molecular cloning of cDNA encoding human interleukin-2 receptor. Nature 1984;311:631-635.
-
(1984)
Nature
, vol.311
, pp. 631-635
-
-
Nikaido, T.1
-
42
-
-
0021707413
-
Cloning, sequence and expression of human interleukin-2 receptor
-
Cosman D, et al. Cloning, sequence and expression of human interleukin-2 receptor. Nature 1984;312:768-771.
-
(1984)
Nature
, vol.312
, pp. 768-771
-
-
Cosman, D.1
-
43
-
-
0023010578
-
Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions
-
Sharon M, Klausner RD, Cullen BR, Chizzonite R, Leonard WJ. Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions. Science 1986;234:859-863.
-
(1986)
Science
, vol.234
, pp. 859-863
-
-
Sharon, M.1
Klausner, R.D.2
Cullen, B.R.3
Chizzonite, R.4
Leonard, W.J.5
-
44
-
-
0023230069
-
The IL-2 receptor beta chain (p70): Role in mediating signals for LAK, NK, and proliferative activities
-
Siegel JP, Sharon M, Smith PL, Leonard WJ. The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activities. Science 1987;238:75-78.
-
(1987)
Science
, vol.238
, pp. 75-78
-
-
Siegel, J.P.1
Sharon, M.2
Smith, P.L.3
Leonard, W.J.4
-
45
-
-
0023280191
-
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells
-
Tsudo M, et al. The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells. Proc Natl Acad Sci USA 1987;84:5394-5398.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5394-5398
-
-
Tsudo, M.1
-
46
-
-
0024403321
-
Interleukin-2 receptor beta chain gene: Generation of three receptor forms by cloned human alpha and beta chain cDNA's
-
Hatakeyama M, et al. Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's. Science 1989;244:551-556.
-
(1989)
Science
, vol.244
, pp. 551-556
-
-
Hatakeyama, M.1
-
47
-
-
0029962080
-
The interleukin-2 receptor gamma chain: Its role in the multiple cytokine receptor complexes and T cell development in XSCID
-
Sugamura K, et al. The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu Rev Immunol 1996;14:179-205.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 179-205
-
-
Sugamura, K.1
-
48
-
-
0029924265
-
The molecular basis of X-linked severe combined immunodeficiency: Defective cytokine receptor signaling
-
Leonard WJ. The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling. Annu Rev Med 1996;47:229-239.
-
(1996)
Annu Rev Med
, vol.47
, pp. 229-239
-
-
Leonard, W.J.1
-
49
-
-
0031410650
-
Signaling from the IL-2 receptor to the nucleus
-
Lin JX, Leonard WJ. Signaling from the IL-2 receptor to the nucleus. Cytokine Growth Factor Rev 1997;8:313-332.
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 313-332
-
-
Lin, J.X.1
Leonard, W.J.2
-
50
-
-
0023225411
-
A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors
-
Dukovich M, et al. A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Nature 1987;327:518-522.
-
(1987)
Nature
, vol.327
, pp. 518-522
-
-
Dukovich, M.1
-
51
-
-
84942877339
-
Interleukin-2
-
Thomson A, Lotze MT, eds. New York: Academic Press
-
Lin JX, Leonard WJ. Interleukin-2. In: Thomson A, Lotze MT, eds. The Cytokine Handbook. New York: Academic Press, 2003: 167-199.
-
(2003)
The Cytokine Handbook
, pp. 167-199
-
-
Lin, J.X.1
Leonard, W.J.2
-
52
-
-
0027688772
-
Immune responses in interleukin-2-deficient mice
-
Kundig TM, Schorle H, Bachmann MF, Hengartner H, Zinkernagel RM, Horak I. Immune responses in interleukin-2-deficient mice. Science 1993;262:1059-1061.
-
(1993)
Science
, vol.262
, pp. 1059-1061
-
-
Kundig, T.M.1
Schorle, H.2
Bachmann, M.F.3
Hengartner, H.4
Zinkernagel, R.M.5
Horak, I.6
-
53
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
54
-
-
0029414785
-
Interleukin-2 deficient mice: A new model to study autoimmunity and self-tolerance
-
Horak I, Lohler J, Ma A, Smith KA. Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance. Immunol Rev 1995;148:35-44.
-
(1995)
Immunol Rev
, vol.148
, pp. 35-44
-
-
Horak, I.1
Lohler, J.2
Ma, A.3
Smith, K.A.4
-
55
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995;3:521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
56
-
-
0030903027
-
Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor
-
Sharfe N, Dadi HK, Shahar M, Roifman CM. Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor. Proc Natl Acad Sci USA 1997;94:3168-3171.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3168-3171
-
-
Sharfe, N.1
Dadi, H.K.2
Shahar, M.3
Roifman, C.M.4
-
57
-
-
0032502801
-
Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
-
Van Parijs L, Abbas AK. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 1998;280:243-248.
-
(1998)
Science
, vol.280
, pp. 243-248
-
-
Van Parijs, L.1
Abbas, A.K.2
-
58
-
-
0033007321
-
Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
-
Lenardo M, et al. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 1999;17:221-253.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 221-253
-
-
Lenardo, M.1
-
59
-
-
0345059209
-
An inherited disorder of lymphocyte apoptosis: The autoimmune lymphoproliferative syndrome
-
Straus SE, Sneller M, Lenardo MJ, Puck JM, Strober W. An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome. Ann Intern Med 1999;130:591-601.
-
(1999)
Ann Intern Med
, vol.130
, pp. 591-601
-
-
Straus, S.E.1
Sneller, M.2
Lenardo, M.J.3
Puck, J.M.4
Strober, W.5
-
60
-
-
0026017971
-
Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
-
Lenardo MJ. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature 1991;353:858-861.
-
(1991)
Nature
, vol.353
, pp. 858-861
-
-
Lenardo, M.J.1
-
61
-
-
0031569514
-
Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor
-
Van Parijs L, Biuckians A, Ibragimov A, Alt FW, Willerford DM, Abbas AK. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. J Immunol 1997;158:3738-3745.
-
(1997)
J Immunol
, vol.158
, pp. 3738-3745
-
-
Van Parijs, L.1
Biuckians, A.2
Ibragimov, A.3
Alt, F.W.4
Willerford, D.M.5
Abbas, A.K.6
-
62
-
-
17544398702
-
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
-
Refaeli Y, Van Parijs L, London CA, Tschopp J, Abbas AK. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998;8:615-623.
-
(1998)
Immunity
, vol.8
, pp. 615-623
-
-
Refaeli, Y.1
Van Parijs, L.2
London, C.A.3
Tschopp, J.4
Abbas, A.K.5
-
63
-
-
0033199317
-
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
-
Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999;11:281-288.
-
(1999)
Immunity
, vol.11
, pp. 281-288
-
-
Van Parijs, L.1
Refaeli, Y.2
Lord, J.D.3
Nelson, B.H.4
Abbas, A.K.5
Baltimore, D.6
-
64
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000;101:455-458.
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
65
-
-
0034084162
-
Regulatory T cells in autoimmmunity
-
Shevach EM. Regulatory T cells in autoimmmunity. Annu Rev Immunol 2000;18:423-449.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 423-449
-
-
Shevach, E.M.1
-
66
-
-
0036857530
-
The role of suppressor T cells in regulation of immune responses
-
McHugh RS, Shevach EM. The role of suppressor T cells in regulation of immune responses. J Allergy Clin Immunol 2002;110:693-702.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 693-702
-
-
McHugh, R.S.1
Shevach, E.M.2
-
67
-
-
0348047537
-
The main function of IL-2 is to promote the development of T regulatory cells
-
Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 2003;74:961-965.
-
(2003)
J Leukoc Biol
, vol.74
, pp. 961-965
-
-
Malek, T.R.1
-
68
-
-
7144259082
-
Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik M, de Moraes ML, Pontoux C, Vasseur F, Penit C. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int Immunol 1998;10:371-378.
-
(1998)
Int Immunol
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
De Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
69
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells. IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida AR, Legrand N, Papiernik M, Freitas AA. Homeostasis of peripheral CD4+ T cells. IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol 2002;169:4850-4860.
-
(2002)
J Immunol
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
71
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek TR, Yu A, Vincek V, Scibelli P, Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 2002;17:167-178.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
72
-
-
0141920630
-
Essential role for STAT5 signaling in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance
-
Antov A, Yang L, Vig M, Baltimore D, Van Parijs L. Essential role for STAT5 signaling in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance. J Immunol 2003;171:3435-3441.
-
(2003)
J Immunol
, vol.171
, pp. 3435-3441
-
-
Antov, A.1
Yang, L.2
Vig, M.3
Baltimore, D.4
Van Parijs, L.5
-
73
-
-
0242580058
-
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice
-
Snow JW, Abraham N, Ma MC, Herndier BG, Pastuszak AW, Goldsmith MA. Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice. J Immunol 2003;171:5042-5050.
-
(2003)
J Immunol
, vol.171
, pp. 5042-5050
-
-
Snow, J.W.1
Abraham, N.2
Ma, M.C.3
Herndier, B.G.4
Pastuszak, A.W.5
Goldsmith, M.A.6
-
74
-
-
1642398043
-
Interleukin 2 plays a central role in Th2 differentiation
-
Cote-Sierra J, et al. Interleukin 2 plays a central role in Th2 differentiation. Proc Natl Acad Sci USA 2004;101:3880-3885.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3880-3885
-
-
Cote-Sierra, J.1
-
75
-
-
0033118752
-
The role of cytokine receptor signaling in lymphocyte development
-
Baird AM, Gerstein RM, Berg LJ. The role of cytokine receptor signaling in lymphocyte development. Curr Opin Immunol 1999;11:157-166.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 157-166
-
-
Baird, A.M.1
Gerstein, R.M.2
Berg, L.J.3
-
76
-
-
0033103099
-
Interleukin-7: Physiological roles and mechanisms of action
-
Hofmeister R, Khaled AR, Benbernou N, Rajnavolgyi E, Muegge K, Durum SK. Interleukin-7: physiological roles and mechanisms of action. Cytokine Growth Factor Rev 1999;10:41-60.
-
(1999)
Cytokine Growth Factor Rev
, vol.10
, pp. 41-60
-
-
Hofmeister, R.1
Khaled, A.R.2
Benbernou, N.3
Rajnavolgyi, E.4
Muegge, K.5
Durum, S.K.6
-
77
-
-
0036624721
-
Interleukin-7: From bench to clinic
-
Fry TJ, Mackall CL. Interleukin-7: from bench to clinic. Blood 2002;99:3892-3904.
-
(2002)
Blood
, vol.99
, pp. 3892-3904
-
-
Fry, T.J.1
Mackall, C.L.2
-
78
-
-
0027209141
-
Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody
-
Grabstein KH, et al. Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody. J Exp Med 1993;178:257-264.
-
(1993)
J Exp Med
, vol.178
, pp. 257-264
-
-
Grabstein, K.H.1
-
79
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon JJ, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994;180:1955-1960.
-
(1994)
J Exp Med
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
-
80
-
-
0028929565
-
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
-
von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995;181:1519-1526.
-
(1995)
J Exp Med
, vol.181
, pp. 1519-1526
-
-
Von Freeden-Jeffry, U.1
Vieira, P.2
Lucian, L.A.3
McNeil, T.4
Burdach, S.E.5
Murray, R.6
-
81
-
-
0031740732
-
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
-
Fuel A, Ziegler SF, Buckley RH, Leonard WJ. Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet 1998;20:394-397.
-
(1998)
Nat Genet
, vol.20
, pp. 394-397
-
-
Fuel, A.1
Ziegler, S.F.2
Buckley, R.H.3
Leonard, W.J.4
-
82
-
-
0024282606
-
Stimulation of B-cell progenitors by cloned murine interleukin-7
-
Namen AE, et al. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 1988;333:571-573.
-
(1988)
Nature
, vol.333
, pp. 571-573
-
-
Namen, A.E.1
-
83
-
-
0026531928
-
Interleukin-7 expression during mouse thymus development
-
Wiles MV, Ruiz P, Imhof BA. Interleukin-7 expression during mouse thymus development. Eur J Immunol 1992;22:1037-1042.
-
(1992)
Eur J Immunol
, vol.22
, pp. 1037-1042
-
-
Wiles, M.V.1
Ruiz, P.2
Imhof, B.A.3
-
84
-
-
0029150219
-
Vascular cell adhesion molecule 1-positive reticular cells express interleukin-7 and stem cell factor in the bone marrow
-
Funk PE, Stephan RP, Witte PL. Vascular cell adhesion molecule 1-positive reticular cells express interleukin-7 and stem cell factor in the bone marrow. Blood 1995;86:2661-2671.
-
(1995)
Blood
, vol.86
, pp. 2661-2671
-
-
Funk, P.E.1
Stephan, R.P.2
Witte, P.L.3
-
85
-
-
0026027238
-
Development of lymphocytes in interleukin 7-transgenic mice
-
Samaridis J, et al. Development of lymphocytes in interleukin 7-transgenic mice. Eur J Immunol 1991;21:453-460.
-
(1991)
Eur J Immunol
, vol.21
, pp. 453-460
-
-
Samaridis, J.1
-
86
-
-
0028924203
-
Lymphoproliferative disorders in IL-7 transgenic mice: Expansion of immature B cells which retain macrophage potential
-
Fisher AG, Burdet C, Bunce C, Merkenschlager M, Ceredig R. Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential. Int Immunol 1995;7:415-423.
-
(1995)
Int Immunol
, vol.7
, pp. 415-423
-
-
Fisher, A.G.1
Burdet, C.2
Bunce, C.3
Merkenschlager, M.4
Ceredig, R.5
-
87
-
-
0029856131
-
Prelymphomatous B cell hyperplasia in the bone marrow of interleukin-7 transgenic mice: Precursor B cell dynamics, microenvironmental organization and osteolysis
-
Valenzona HO, Pointer R, Ceredig R, Osmond DG. Prelymphomatous B cell hyperplasia in the bone marrow of interleukin-7 transgenic mice: precursor B cell dynamics, microenvironmental organization and osteolysis. Exp Hematol 1996;24:1521-1529.
-
(1996)
Exp Hematol
, vol.24
, pp. 1521-1529
-
-
Valenzona, H.O.1
Pointer, R.2
Ceredig, R.3
Osmond, D.G.4
-
88
-
-
0034968595
-
Control of chromatin accessibility for V(D)J recombination by interleukin-7
-
Huang J, Muegge K. Control of chromatin accessibility for V(D)J recombination by interleukin-7. J Leukoc Biol 2001;69:907-911.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 907-911
-
-
Huang, J.1
Muegge, K.2
-
89
-
-
2242434790
-
Nonrandom X chromosome inactivation in B cells from carriers of X chromosome-linked severe combined immunodeficiency
-
Conley ME, Lavoie A, Briggs C, Brown P, Guerra C, Puck JM. Nonrandom X chromosome inactivation in B cells from carriers of X chromosome-linked severe combined immunodeficiency. Proc Natl Acad Sci USA 1988;85:3090-3094.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 3090-3094
-
-
Conley, M.E.1
Lavoie, A.2
Briggs, C.3
Brown, P.4
Guerra, C.5
Puck, J.M.6
-
90
-
-
0035471754
-
Interleukin-7: Master regulator of peripheral T-cell homeostasis?
-
Fry TJ, Mackall CL. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol 2001;22:564-571.
-
(2001)
Trends Immunol
, vol.22
, pp. 564-571
-
-
Fry, T.J.1
Mackall, C.L.2
-
91
-
-
0036672918
-
Maintaining the norm: T-cell homeostasis
-
Jameson SC. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol 2002;2:547-556.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 547-556
-
-
Jameson, S.C.1
-
92
-
-
0038655228
-
Cytokine control of memory T-cell development and survival
-
Schluns KS, Lefrancois L. Cytokine control of memory T-cell development and survival. Nat Rev Immunol 2003;3:269-279.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 269-279
-
-
Schluns, K.S.1
Lefrancois, L.2
-
93
-
-
0037460105
-
Cytokines and T cell homeostasis
-
Sprent J, Surh CD. Cytokines and T cell homeostasis. Immunol Lett 2003;85: 145-149.
-
(2003)
Immunol Lett
, vol.85
, pp. 145-149
-
-
Sprent, J.1
Surh, C.D.2
-
94
-
-
17444433046
-
Homeostatic control of T-cell generation in neonates
-
Schonland SO, et al. Homeostatic control of T-cell generation in neonates. Blood 2003;102:1428-1434.
-
(2003)
Blood
, vol.102
, pp. 1428-1434
-
-
Schonland, S.O.1
-
95
-
-
0037243278
-
Neonates support lymphopenia-induced proliferation
-
Min B, McHugh R, Sempowski GD, Mackall C, Foucras G, Paul WE. Neonates support lymphopenia-induced proliferation. Immunity 2003;18:131-140.
-
(2003)
Immunity
, vol.18
, pp. 131-140
-
-
Min, B.1
McHugh, R.2
Sempowski, G.D.3
Mackall, C.4
Foucras, G.5
Paul, W.E.6
-
96
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naive and memory CDS T cells in vivo
-
Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CDS T cells in vivo. Nat Immunol 2000;1:426-432.
-
(2000)
Nat Immunol
, vol.1
, pp. 426-432
-
-
Schluns, K.S.1
Kieper, W.C.2
Jameson, S.C.3
Lefrancois, L.4
-
97
-
-
0035902513
-
IL-7 is critical for homeostatic proliferation and survival of naive T cells
-
Tan JT, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA 2001;98:8732-8737.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8732-8737
-
-
Tan, J.T.1
-
98
-
-
0038487052
-
Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
-
Seddon B, Tomlinson P, Zamoyska R. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol 2003;4:680-686.
-
(2003)
Nat Immunol
, vol.4
, pp. 680-686
-
-
Seddon, B.1
Tomlinson, P.2
Zamoyska, R.3
-
99
-
-
0037124328
-
Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells
-
Kieper WC, et al. Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells. J Exp Med 2002;195:1533-1539.
-
(2002)
J Exp Med
, vol.195
, pp. 1533-1539
-
-
Kieper, W.C.1
-
100
-
-
0037124366
-
Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells
-
Tan JT, Ernst B, Kieper WC, LeRoy E, Sprent J, Surh CD. Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med 2002;195:1523-1532.
-
(2002)
J Exp Med
, vol.195
, pp. 1523-1532
-
-
Tan, J.T.1
Ernst, B.2
Kieper, W.C.3
LeRoy, E.4
Sprent, J.5
Surh, C.D.6
-
101
-
-
0036890419
-
Interleukin-15 and the regulation of lymphoid homeostasis
-
Lodolce J, et al. Interleukin-15 and the regulation of lymphoid homeostasis. Mol Immunol 2002;39:537-544.
-
(2002)
Mol Immunol
, vol.39
, pp. 537-544
-
-
Lodolce, J.1
-
102
-
-
0037109077
-
IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes
-
Xue HH, et al. IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes. Proc Natl Acad Sci USA 2002;99:13759-13764.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13759-13764
-
-
Xue, H.H.1
-
103
-
-
0033696860
-
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
-
Townsend JM, Fallon GP, Matthews JD, Smith P, John EH, McKenzie NA. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 2000;13:573-583.
-
(2000)
Immunity
, vol.13
, pp. 573-583
-
-
Townsend, J.M.1
Fallon, G.P.2
Matthews, J.D.3
Smith, P.4
John, E.H.5
McKenzie, N.A.6
-
104
-
-
0028293650
-
Thymic lymphomas in interleukin 9 transgenic mice
-
Renauld JC, et al. Thymic lymphomas in interleukin 9 transgenic mice. Oncogene 1994;9:1327-1332.
-
(1994)
Oncogene
, vol.9
, pp. 1327-1332
-
-
Renauld, J.C.1
-
105
-
-
0028276796
-
A lymphokine, provisionally desinated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
-
Burton JD, et al. A lymphokine, provisionally desinated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 1994;91:4935-4939.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4935-4939
-
-
Burton, J.D.1
-
106
-
-
0028179054
-
Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor
-
Grabstein KH, et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994;264:965-968.
-
(1994)
Science
, vol.264
, pp. 965-968
-
-
Grabstein, K.H.1
-
107
-
-
0029006450
-
IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2
-
Giri JG, Anderson DM, Kumaki S, Park LS, Grabstein KH, Cosman D. IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2. J Leukoc Biol 1995;57:763-766.
-
(1995)
J Leukoc Biol
, vol.57
, pp. 763-766
-
-
Giri, J.G.1
Anderson, D.M.2
Kumaki, S.3
Park, L.S.4
Grabstein, K.H.5
Cosman, D.6
-
108
-
-
0035102242
-
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
-
Waldmann TA, Dubois S, Tagaya Y. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 2001;14:105-110.
-
(2001)
Immunity
, vol.14
, pp. 105-110
-
-
Waldmann, T.A.1
Dubois, S.2
Tagaya, Y.3
-
109
-
-
0031051547
-
Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain
-
Suzuki H, Duncan GS, Takimoto H, Mak TW. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain. J Exp Med 1997;185:499-505.
-
(1997)
J Exp Med
, vol.185
, pp. 499-505
-
-
Suzuki, H.1
Duncan, G.S.2
Takimoto, H.3
Mak, T.W.4
-
110
-
-
0032211699
-
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
-
Lodolce JP, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
-
(1998)
Immunity
, vol.9
, pp. 669-676
-
-
Lodolce, J.P.1
-
111
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
-
Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771-780.
-
(2000)
J Exp Med
, vol.191
, pp. 771-780
-
-
Kennedy, M.K.1
-
112
-
-
0037093844
-
Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
-
Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 2002;168:4827-4831.
-
(2002)
J Immunol
, vol.168
, pp. 4827-4831
-
-
Schluns, K.S.1
Williams, K.2
Ma, A.3
Zheng, X.X.4
Lefrancois, L.5
-
113
-
-
0037124341
-
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
-
Becker TC, et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002;195:1541-1548.
-
(2002)
J Exp Med
, vol.195
, pp. 1541-1548
-
-
Becker, T.C.1
-
114
-
-
0034633683
-
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice
-
Marks-Konczalik J, et al. IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. Proc Natl Acad Sci USA 2000;97:11445-11450.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11445-11450
-
-
Marks-Konczalik, J.1
-
115
-
-
0035862325
-
Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8(+) T Cells
-
Fehniger TA, et al. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8(+) T Cells. J Exp Med 2001;193:219-232.
-
(2001)
J Exp Med
, vol.193
, pp. 219-232
-
-
Fehniger, T.A.1
-
116
-
-
0037218561
-
A role for Stat5 in CD8+ T cell homeostasis
-
Kelly J, Spolski R, Imada K, Bollenbacher J, Lee S, Leonard WJ. A role for Stat5 in CD8+ T cell homeostasis. J Immunol 2003;170:210-217.
-
(2003)
J Immunol
, vol.170
, pp. 210-217
-
-
Kelly, J.1
Spolski, R.2
Imada, K.3
Bollenbacher, J.4
Lee, S.5
Leonard, W.J.6
-
117
-
-
0033504733
-
Molecular basis of T-cell differentiation
-
Flavell RA, et al. Molecular basis of T-cell differentiation. Cold Spring Harb Symp Quant Biol 1999;64:563-571.
-
(1999)
Cold Spring Harb Symp Quant Biol
, vol.64
, pp. 563-571
-
-
Flavell, R.A.1
-
118
-
-
0034571173
-
The molecular basis of T helper 1 and T helper 2 cell differentiation
-
O'Garra A, Arai N. The molecular basis of T helper 1 and T helper 2 cell differentiation. Trends Cell Biol 2000;10:542-550.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 542-550
-
-
O'Garra, A.1
Arai, N.2
-
119
-
-
0026328818
-
Generation and analysis of interleukin-4 deficient mice
-
Kuhn R, Rajewsky K, Muller W. Generation and analysis of interleukin-4 deficient mice. Science 1991;254:707-710.
-
(1991)
Science
, vol.254
, pp. 707-710
-
-
Kuhn, R.1
Rajewsky, K.2
Muller, W.3
-
120
-
-
0030931043
-
An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice
-
Noben-Trauth N, Shultz LD, Brombacher F, Urban JF Jr, Gu H, Paul WE. An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci USA 1997;94:10838-10843.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10838-10843
-
-
Noben-Trauth, N.1
Shultz, L.D.2
Brombacher, F.3
Urban Jr., J.F.4
Gu, H.5
Paul, W.E.6
-
121
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996;4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
122
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996;380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
-
123
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda K, et al. Essential role of Stat6 in IL-4 signalling. Nature 1996;380:627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
-
124
-
-
0037775352
-
IL-13 effector functions
-
Wynn TA. IL-13 effector functions. Annu Rev Immunol 2003;21:425-456.
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 425-456
-
-
Wynn, T.A.1
-
125
-
-
0033010373
-
The IL-4 receptor: Signaling mechanisms and biologic functions
-
Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE. The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol 1999;17:701-738.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
126
-
-
0034633734
-
Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain
-
Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ. Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci USA 2000;97:11439-11444.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11439-11444
-
-
Ozaki, K.1
Kikly, K.2
Michalovich, D.3
Young, P.R.4
Leonard, W.J.5
-
127
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak J, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000;408:57-63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
-
128
-
-
18344394955
-
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity
-
Kasaian MT, et al. IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity 2002;16:559-569.
-
(2002)
Immunity
, vol.16
, pp. 559-569
-
-
Kasaian, M.T.1
-
129
-
-
0037037544
-
Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells
-
Wurster AL, et al. Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. J Exp Med 2002;196:969-977.
-
(2002)
J Exp Med
, vol.196
, pp. 969-977
-
-
Wurster, A.L.1
-
130
-
-
0036784616
-
IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response
-
Strengell M, Sareneva T, Foster D, Julkunen I, Matikainen S. IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response. J Immunol 2002;169:3600-3605.
-
(2002)
J Immunol
, vol.169
, pp. 3600-3605
-
-
Strengell, M.1
Sareneva, T.2
Foster, D.3
Julkunen, I.4
Matikainen, S.5
-
131
-
-
0031440585
-
Advances in the understanding of cytokine signal transduction: The role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency
-
O'Shea JJ, Notarangelo LD, Johnston JA, Candotti F. Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency. J Clin Immunol 1997;17:431-447.
-
(1997)
J Clin Immunol
, vol.17
, pp. 431-447
-
-
O'Shea, J.J.1
Notarangelo, L.D.2
Johnston, J.A.3
Candotti, F.4
-
132
-
-
3242742473
-
Type 1 cytokines and interferons and their receptors
-
Paul WE, ed. Philadelphia: Lippincott Williams & Wilkins
-
Leonard WJ. Type 1 cytokines and interferons and their receptors. In: Paul WE, ed. Fundamental Immunology. Philadelphia: Lippincott Williams & Wilkins, 2003: 701-747.
-
(2003)
Fundamental Immunology
, pp. 701-747
-
-
Leonard, W.J.1
-
133
-
-
0028114542
-
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor
-
Boussiotis VA, et al. Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. Science 1994;266:1039-1042.
-
(1994)
Science
, vol.266
, pp. 1039-1042
-
-
Boussiotis, V.A.1
-
134
-
-
0027993022
-
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
-
Miyazaki T, et al. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science 1994;266:1045-1047.
-
(1994)
Science
, vol.266
, pp. 1045-1047
-
-
Miyazaki, T.1
-
135
-
-
0032562772
-
Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta
-
Zhu MH, Berry JA, Russell SM, Leonard WJ. Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta. J Biol Chem 1998;273:10719-10725.
-
(1998)
J Biol Chem
, vol.273
, pp. 10719-10725
-
-
Zhu, M.H.1
Berry, J.A.2
Russell, S.M.3
Leonard, W.J.4
-
136
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID. Essential role of Jak3 in lymphoid development
-
Russell SM, et al. Mutation of Jak3 in a patient with SCID. Essential role of Jak3 in lymphoid development. Science 1995;270:797-799.
-
(1995)
Science
, vol.270
, pp. 797-799
-
-
Russell, S.M.1
-
137
-
-
0029164841
-
Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)
-
Macchi P, et al. Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID). Nature 1995;377:65-68.
-
(1995)
Nature
, vol.377
, pp. 65-68
-
-
Macchi, P.1
-
138
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig SJ, et al. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 1998;93:373-383.
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.J.1
-
139
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 2002;109:S121-S131.
-
(2002)
Cell
, vol.109
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
140
-
-
0034501027
-
Of genes and phenotypes: The immunological and molecular spectrum of combined immune deficiency. Defects of the gamma (c)-JAK3 signaling pathway as a model
-
Notarangelo LD, et al. Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma (c)-JAK3 signaling pathway as a model. Immunol Rev 2000;178:39-48.
-
(2000)
Immunol Rev
, vol.178
, pp. 39-48
-
-
Notarangelo, L.D.1
-
141
-
-
0030062769
-
Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state
-
Briscoe J, et al. Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state. EMBOJ 1996;15:799-809.
-
(1996)
EMBO J
, vol.15
, pp. 799-809
-
-
Briscoe, J.1
-
142
-
-
0029786754
-
Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase
-
Gauzzi MC, Velazquez L, McKendry R, Mogensen KE, Fellous M, Pellegrini S. Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase. J Biol Chem 1996;271:20494-20500.
-
(1996)
J Biol Chem
, vol.271
, pp. 20494-20500
-
-
Gauzzi, M.C.1
Velazquez, L.2
McKendry, R.3
Mogensen, K.E.4
Fellous, M.5
Pellegrini, S.6
-
143
-
-
0033965488
-
Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: Evidence for interactions between the kinase and pseudokinase domains
-
Chen M, et al. Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains. Mol Cell Biol 2000;20:947-956.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 947-956
-
-
Chen, M.1
-
144
-
-
0034949188
-
Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus
-
Yeh JH, et al. Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus. Mol Cell Biol 2001;21:4515-4527.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4515-4527
-
-
Yeh, J.H.1
-
145
-
-
0037033012
-
The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction
-
Saharinen P, Silvennoinen O. The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction. J Biol Chem 2002;277:47954-47963.
-
(2002)
J Biol Chem
, vol.277
, pp. 47954-47963
-
-
Saharinen, P.1
Silvennoinen, O.2
-
146
-
-
0031017533
-
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways
-
Luo H, et al. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol Cell Biol 1997;17:1562-1571.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1562-1571
-
-
Luo, H.1
-
147
-
-
0028097219
-
Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
-
Frank SJ, Gilliland G, Kraft AS, Arnold CS. Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 1994;135:2228-2239.
-
(1994)
Endocrinology
, vol.135
, pp. 2228-2239
-
-
Frank, S.J.1
Gilliland, G.2
Kraft, A.S.3
Arnold, C.S.4
-
148
-
-
0029024882
-
Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
-
Frank SJ, et al. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem 1995;270:14776-14785.
-
(1995)
J Biol Chem
, vol.270
, pp. 14776-14785
-
-
Frank, S.J.1
-
149
-
-
0029011115
-
The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain
-
Zhao Y, Wagner F, Frank SJ, Kraft AS. The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain. J Biol Chem 1995;270:13814-13818.
-
(1995)
J Biol Chem
, vol.270
, pp. 13814-13818
-
-
Zhao, Y.1
Wagner, F.2
Frank, S.J.3
Kraft, A.S.4
-
150
-
-
0031009816
-
The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals
-
Chen M, et al. The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals. Proc Natl Acad Sci USA 1997;94:6910-6915.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6910-6915
-
-
Chen, M.1
-
151
-
-
0033559793
-
Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3-receptor interaction domain
-
Cacalano NA, et al. Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain. EMBO J 1999;18:1549-1558.
-
(1999)
EMBO J
, vol.18
, pp. 1549-1558
-
-
Cacalano, N.A.1
-
152
-
-
1542343959
-
Janus kinase 3 (JAK3) deficiency: Clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation
-
Roberts JL, et al. Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation. Blood 2004;103:2009-2018.
-
(2004)
Blood
, vol.103
, pp. 2009-2018
-
-
Roberts, J.L.1
-
153
-
-
18244393495
-
Unexpected effects of PERM domain mutations on catalytic activity of Jak3: Structural implication for Janus kinases
-
Zhou YJ, et al. Unexpected effects of PERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases. Mol Cell 2001;8:959-969.
-
(2001)
Mol Cell
, vol.8
, pp. 959-969
-
-
Zhou, Y.J.1
-
154
-
-
0028933799
-
Signaling through the hematopoietic cytokine receptors
-
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O. Signaling through the hematopoietic cytokine receptors. Annu Rev Immunol 1995;13:369-398.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 369-398
-
-
Ihle, J.N.1
Witthuhn, B.A.2
Quelle, F.W.3
Yamamoto, K.4
Silvennoinen, O.5
-
155
-
-
0037007207
-
Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha
-
McBride KM, Banninger G, McDonald C, Reich NC. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha. EMBO J 2002;21:1754-1763.
-
(2002)
EMBO J
, vol.21
, pp. 1754-1763
-
-
McBride, K.M.1
Banninger, G.2
McDonald, C.3
Reich, N.C.4
-
156
-
-
33750216805
-
Mechanisms and biological consequences of STAT signaling by cytokines that share the common cytokine receptor γ chain, γc
-
Sehgal PB, Levy D, Hirano T, eds. Boston: Kluwer Academic
-
Lin JX, Leonard WJ. Mechanisms and biological consequences of STAT signaling by cytokines that share the common cytokine receptor γ chain, γc. In: Sehgal PB, Levy D, Hirano T, eds. Signal Transducers and Activators of Transcription (STATs): Activation and Biology. Boston: Kluwer Academic, 2003.
-
(2003)
Signal Transducers and Activators of Transcription (STATs): Activation and Biology
-
-
Lin, J.X.1
Leonard, W.J.2
-
157
-
-
0035367819
-
Signaling by type I and II cytokine receptors: Ten years after
-
Gadina M, et al. Signaling by type I and II cytokine receptors: ten years after. Curr Opin Immunol 2001;13:363-373.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 363-373
-
-
Gadina, M.1
-
158
-
-
0031057929
-
Stat5a is mandatory for adult mammary gland development and lactogenesis
-
Liu X, Robinson GW, Wagner KU, Garrett L, Wynshaw-Boris A, Hennighausen L. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev 1997;11:179-186.
-
(1997)
Genes Dev
, vol.11
, pp. 179-186
-
-
Liu, X.1
Robinson, G.W.2
Wagner, K.U.3
Garrett, L.4
Wynshaw-Boris, A.5
Hennighausen, L.6
-
159
-
-
0030833570
-
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
-
Udy GB, et al. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci USA 1997;94:7239-7244.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7239-7244
-
-
Udy, G.B.1
-
160
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
Teglund S, et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 1998;93:841-850.
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
-
161
-
-
0031433362
-
An indirect effect of Stat5a in IL-2-induced proliferation: A critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction
-
Nakajima H, et al. An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction. Immunity 1997;7:691-701.
-
(1997)
Immunity
, vol.7
, pp. 691-701
-
-
Nakajima, H.1
-
162
-
-
0031774896
-
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
-
Imada K, et al. Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity. J Exp Med 1998;188:2067-2074.
-
(1998)
J Exp Med
, vol.188
, pp. 2067-2074
-
-
Imada, K.1
-
163
-
-
0033082138
-
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
-
Moriggl R, et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 1999;10:249-259.
-
(1999)
Immunity
, vol.10
, pp. 249-259
-
-
Moriggl, R.1
-
164
-
-
0029124056
-
Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain
-
Goldsmith MA, et al. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. J Biol Chem 1995;270:21729-21737.
-
(1995)
J Biol Chem
, vol.270
, pp. 21729-21737
-
-
Goldsmith, M.A.1
-
165
-
-
0028962572
-
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
-
Lin JX, et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 1995;2:331-339.
-
(1995)
Immunity
, vol.2
, pp. 331-339
-
-
Lin, J.X.1
-
166
-
-
0029875230
-
Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
-
Friedmann MC, Migone TS, Russell SM, Leonard WJ. Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc Natl Acad Sci USA 1996;93:2077-2082.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2077-2082
-
-
Friedmann, M.C.1
Migone, T.S.2
Russell, S.M.3
Leonard, W.J.4
-
167
-
-
0031836964
-
Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
-
Onishi M, et al. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol Cell Biol 1998;18:3871-3879.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3871-3879
-
-
Onishi, M.1
-
168
-
-
0029005549
-
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I
-
Migone TS, et al. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science 1995;269:79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.S.1
-
169
-
-
0037062489
-
Constitutive activation of Stat5a by retrovirus integration in early pre-B lymphomas of SL/Kh strain mice
-
Tsuruyama T, Nakamura T, Jin G, Ozeki M, Yamada Y, Hiai H. Constitutive activation of Stat5a by retrovirus integration in early pre-B lymphomas of SL/Kh strain mice. Proc Natl Acad Sci USA 2002;99:8253-8258.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8253-8258
-
-
Tsuruyama, T.1
Nakamura, T.2
Jin, G.3
Ozeki, M.4
Yamada, Y.5
Hiai, H.6
-
170
-
-
0038152914
-
Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma
-
Kelly JA, et al. Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma. J Exp Med 2003;198:79-89.
-
(2003)
J Exp Med
, vol.198
, pp. 79-89
-
-
Kelly, J.A.1
-
171
-
-
0029853971
-
An IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I (Y) and a GATA family protein
-
John S, Robbins CM, Leonard WJ. An IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I (Y) and a GATA family protein. EMBO J 1996;15:5627-5635.
-
(1996)
EMBO J
, vol.15
, pp. 5627-5635
-
-
John, S.1
Robbins, C.M.2
Leonard, W.J.3
-
172
-
-
0034897188
-
The basis for IL-2-induced IL-2 receptor a chain gene regulation: Importance of two widely separated IL-2 response elements
-
Kim HP, Kelly J, Leonard WJ. The basis for IL-2-induced IL-2 receptor a chain gene regulation: importance of two widely separated IL-2 response elements. Immunity 2001;15:159-172.
-
(2001)
Immunity
, vol.15
, pp. 159-172
-
-
Kim, H.P.1
Kelly, J.2
Leonard, W.J.3
-
173
-
-
0033199236
-
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
-
Nosaka T, Kawashima T, Misawa K, Ikuta K, Mui AL, Kitamura T. STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J 1999;18:4754-4765.
-
(1999)
EMBO J
, vol.18
, pp. 4754-4765
-
-
Nosaka, T.1
Kawashima, T.2
Misawa, K.3
Ikuta, K.4
Mui, A.L.5
Kitamura, T.6
-
174
-
-
0033560095
-
Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells
-
Matikainen S, Sareneva T, Ronni T, Lehtonen A, Koskinen PJ, Julkunen I. Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells. Blood 1999;93:1980-1991.
-
(1999)
Blood
, vol.93
, pp. 1980-1991
-
-
Matikainen, S.1
Sareneva, T.2
Ronni, T.3
Lehtonen, A.4
Koskinen, P.J.5
Julkunen, I.6
-
175
-
-
0033106168
-
Transcriptional regulation of the cyclin D1 promoter by STAT5: Its involvement in cytokine-dependent growth of hematopoietic cells
-
Matsumura I, et al. Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J 1999;18:1367-1377.
-
(1999)
EMBO J
, vol.18
, pp. 1367-1377
-
-
Matsumura, I.1
-
176
-
-
0035253352
-
Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2
-
Martino A, Holmes JHT, Lord JD, Moon JJ, Nelson BH. Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2. J Immunol 2001;166:1723-1729.
-
(2001)
J Immunol
, vol.166
, pp. 1723-1729
-
-
Martino, A.1
Holmes, J.H.T.2
Lord, J.D.3
Moon, J.J.4
Nelson, B.H.5
-
177
-
-
0344064893
-
Stat5 activation plays a critical role in Th2 differentiation
-
Zhu J, Cote-Sierra J, Guo L, Paul WE. Stat5 activation plays a critical role in Th2 differentiation. Immunity 2003;19:739-748.
-
(2003)
Immunity
, vol.19
, pp. 739-748
-
-
Zhu, J.1
Cote-Sierra, J.2
Guo, L.3
Paul, W.E.4
-
178
-
-
0142219240
-
Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation
-
Blaeser F, et al. Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. JExp Med 2003;198:1189-1200.
-
(2003)
JExp Med
, vol.198
, pp. 1189-1200
-
-
Blaeser, F.1
-
179
-
-
0029115522
-
Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15
-
Johnston JA, et al. Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. Proc Natl Acad Sci USA 1995;92:8705-8709.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8705-8709
-
-
Johnston, J.A.1
-
180
-
-
0033520477
-
Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9
-
Demoulin JB, Van Roost E, Stevens M, Groner B, Renauld JC. Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9. J Biol Chem 1999;274:25855-25861.
-
(1999)
J Biol Chem
, vol.274
, pp. 25855-25861
-
-
Demoulin, J.B.1
Van Roost, E.2
Stevens, M.3
Groner, B.4
Renauld, J.C.5
-
181
-
-
0037514399
-
IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells
-
Strengell M, et al. IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells. J Immunol 2003;170:5464-5469.
-
(2003)
J Immunol
, vol.170
, pp. 5464-5469
-
-
Strengell, M.1
-
182
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda K, et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci USA 1997;94:3801-3804.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
-
183
-
-
0034657958
-
Roles of STAT3 defined by tissue-specific gene targeting
-
Akira S. Roles of STAT3 defined by tissue-specific gene targeting. Oncogene 2000;19:2607-2611.
-
(2000)
Oncogene
, vol.19
, pp. 2607-2611
-
-
Akira, S.1
-
184
-
-
0031758022
-
Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes
-
Akaishi H, et al. Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes. Int Immunol 1998;10:1747-1751.
-
(1998)
Int Immunol
, vol.10
, pp. 1747-1751
-
-
Akaishi, H.1
-
185
-
-
0030024563
-
Targeted disruption of the mouse Stat 1 gene results in compromised innate immunity to viral disease
-
Durbin JE, Hackenmiller R, Simon MC, Levy DE. Targeted disruption of the mouse Stat 1 gene results in compromised innate immunity to viral disease. Cell 1996;84:443-450.
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
186
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz MA, et al. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996;84:431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
-
187
-
-
0036200194
-
Protein kinase B (Akt) regulation and function in T lymphocytes
-
Cantrell D. Protein kinase B (Akt) regulation and function in T lymphocytes. Semin Immunol 2002;14:19-26.
-
(2002)
Semin Immunol
, vol.14
, pp. 19-26
-
-
Cantrell, D.1
-
188
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci USA 1997;94:3627-3632.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
189
-
-
0037080219
-
IL-2 and related cytokines can promote T cell survival by activating AKT
-
Kelly E, Won A, Refaeli Y, Van Parijs L. IL-2 and related cytokines can promote T cell survival by activating AKT. J Immunol 2002;168:597-603.
-
(2002)
J Immunol
, vol.168
, pp. 597-603
-
-
Kelly, E.1
Won, A.2
Refaeli, Y.3
Van Parijs, L.4
-
190
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
-
192
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
-
193
-
-
0037094096
-
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
-
Stahl M, et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002;168:5024-5031.
-
(2002)
J Immunol
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
-
194
-
-
0031433335
-
Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
-
Brennan P, Babbage JW, Burgering BM, Groner B, Reif K, Cantrell DA. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 1997;7:679-689.
-
(1997)
Immunity
, vol.7
, pp. 679-689
-
-
Brennan, P.1
Babbage, J.W.2
Burgering, B.M.3
Groner, B.4
Reif, K.5
Cantrell, D.A.6
-
195
-
-
0029983731
-
The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis
-
Corcoran AE, Smart FM, Cowling RJ, Crompton T, Owen MJ, Venkitaraman AR. The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J 1996;15:1924-1932.
-
(1996)
EMBO J
, vol.15
, pp. 1924-1932
-
-
Corcoran, A.E.1
Smart, F.M.2
Cowling, R.J.3
Crompton, T.4
Owen, M.J.5
Venkitaraman, A.R.6
-
196
-
-
0033136288
-
Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors
-
Pallard C, Stegmann AP, van Kleffens T, Smart F, Venkitaraman A, Spits H. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999;10:525-535.
-
(1999)
Immunity
, vol.10
, pp. 525-535
-
-
Pallard, C.1
Stegmann, A.P.2
Van Kleffens, T.3
Smart, F.4
Venkitaraman, A.5
Spits, H.6
-
197
-
-
0035971435
-
Signal transduction by MAP kinases in T lymphocytes
-
Rincon M, Flavell RA, Davis RJ. Signal transduction by MAP kinases in T lymphocytes. Oncogene 2001;20:2490-2497.
-
(2001)
Oncogene
, vol.20
, pp. 2490-2497
-
-
Rincon, M.1
Flavell, R.A.2
Davis, R.J.3
-
199
-
-
0038578688
-
GTPases and T cell activation
-
Cantrell DA. GTPases and T cell activation. Immunol Rev 2003;192:122-130.
-
(2003)
Immunol Rev
, vol.192
, pp. 122-130
-
-
Cantrell, D.A.1
-
200
-
-
0036359608
-
Transgenic analysis of thymocyte signal transduction
-
Cantrell DA. Transgenic analysis of thymocyte signal transduction. Nat Rev Immunol 2002;2:20-27.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 20-27
-
-
Cantrell, D.A.1
-
201
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
Pages G, et al. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 1999;286:1374-1377.
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pages, G.1
-
202
-
-
0036848708
-
RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation
-
Priatel JJ, Teh SJ, Dower NA, Stone JC, Teh HS. RasGRP1 transduces
-
(2002)
Immunity
, vol.17
, pp. 617-627
-
-
Priatel, J.J.1
Teh, S.J.2
Dower, N.A.3
Stone, J.C.4
Teh, H.S.5
-
203
-
-
0042432047
-
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1
-
Layer K, et al. Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1. Immunity 2003;19:243-255.
-
(2003)
Immunity
, vol.19
, pp. 243-255
-
-
Layer, K.1
-
204
-
-
0028299984
-
In search of cytokine-response genes
-
Beadling C, Smith KA. In search of cytokine-response genes. Immunol Today 1994;15:197-199.
-
(1994)
Immunol Today
, vol.15
, pp. 197-199
-
-
Beadling, C.1
Smith, K.A.2
-
205
-
-
0043247592
-
DNA array analysis of interleukin-2-regulated immediate/early genes
-
Beadling C, Smith KA. DNA array analysis of interleukin-2-regulated immediate/early genes. Med Immunol 2002;1:2.
-
(2002)
Med Immunol
, vol.1
, pp. 2
-
-
Beadling, C.1
Smith, K.A.2
-
206
-
-
0037197925
-
IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells
-
Liu K, Catalfamo M, Li Y, Henkart PA, Weng NP. IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells. Proc Natl Acad Sci USA 2002;99:6192-6197.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6192-6197
-
-
Liu, K.1
Catalfamo, M.2
Li, Y.3
Henkart, P.A.4
Weng, N.P.5
-
207
-
-
0038813748
-
Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling
-
Kovanen PE, et al. Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling. J Biol Chem 2003;278:5205-5213.
-
(2003)
J Biol Chem
, vol.278
, pp. 5205-5213
-
-
Kovanen, P.E.1
-
208
-
-
0034075845
-
Transcript imaging of the development of human T helper cells using oligonucleotide arrays
-
Rogge L, et al. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nat Genet 2000;25:96-101.
-
(2000)
Nat Genet
, vol.25
, pp. 96-101
-
-
Rogge, L.1
-
209
-
-
0035224492
-
Distinct gene expression profiles of human type 1 and type 2 T helper cells
-
RESEARCH0022
-
Hamalainen H, Zhou H, Chou W, Hashizume H, Heller R, Lahesmaa R. Distinct gene expression profiles of human type 1 and type 2 T helper cells. Genome Biol 2001;2: RESEARCH0022.
-
(2001)
Genome Biol
, vol.2
-
-
Hamalainen, H.1
Zhou, H.2
Chou, W.3
Hashizume, H.4
Heller, R.5
Lahesmaa, R.6
-
210
-
-
0035884779
-
Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells
-
Chtanova T, Kemp RA, Sutherland AP, Ronchese F, Mackay CR. Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells. J Immunol 2001;167:3057-3063.
-
(2001)
J Immunol
, vol.167
, pp. 3057-3063
-
-
Chtanova, T.1
Kemp, R.A.2
Sutherland, A.P.3
Ronchese, F.4
Mackay, C.R.5
-
211
-
-
1542327676
-
Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation
-
Lu B, Zagouras P, Fischer JE, Lu J, Li B, Flavell RA. Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation. Proc Natl Acad Sci USA 2004;101:3023-3028.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3023-3028
-
-
Lu, B.1
Zagouras, P.2
Fischer, J.E.3
Lu, J.4
Li, B.5
Flavell, R.A.6
-
212
-
-
0037015038
-
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
-
Diehn M, et al. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci USA 2002;99:11796-11801.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11796-11801
-
-
Diehn, M.1
-
213
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
Riley JL, et al. Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc Natl Acad Sci USA 2002;99:11790-11795.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11790-11795
-
-
Riley, J.L.1
-
214
-
-
0036467533
-
Cutting edge: STAT6 serves as a positive and negative regulator of gene expression in IL-4-stimulated B lymphocytes
-
Schroder AJ, Pavlidis P, Arimura A, Capece D, Rothman PB. Cutting edge: STAT6 serves as a positive and negative regulator of gene expression in IL-4-stimulated B lymphocytes. J Immunol 2002;168:996-1000.
-
(2002)
J Immunol
, vol.168
, pp. 996-1000
-
-
Schroder, A.J.1
Pavlidis, P.2
Arimura, A.3
Capece, D.4
Rothman, P.B.5
-
215
-
-
0141920618
-
Identification of novel IL-4/Stat6-regulated genes in T lymphocytes
-
Chen Z, Lund R, Aittokallio T, Kosonen M, Nevalainen O, Lahesmaa R. Identification of novel IL-4/Stat6-regulated genes in T lymphocytes. J Immunol 2003;171:3627-3635.
-
(2003)
J Immunol
, vol.171
, pp. 3627-3635
-
-
Chen, Z.1
Lund, R.2
Aittokallio, T.3
Kosonen, M.4
Nevalainen, O.5
Lahesmaa, R.6
-
216
-
-
0346121599
-
Suppressors of cytokine signaling and immunity
-
Kubo M, Kanada T, Yoshimura A. Suppressors of cytokine signaling and immunity. Nat Immun 2003;4:1169-1176.
-
(2003)
Nat Immun
, vol.4
, pp. 1169-1176
-
-
Kubo, M.1
Kanada, T.2
Yoshimura, A.3
-
217
-
-
0347093460
-
Inhibitors of cytokine signal transduction
-
Wormald S, Hilton DJ. Inhibitors of cytokine signal transduction. J Biol Chem 2004;279:821-824.
-
(2004)
J Biol Chem
, vol.279
, pp. 821-824
-
-
Wormald, S.1
Hilton, D.J.2
-
218
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
-
Alexander WS, et al. SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 1999;98:597-608.
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
-
219
-
-
0344394485
-
Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes
-
Ilangumaran S, et al. Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes. Blood 2003;102:4115-4122.
-
(2003)
Blood
, vol.102
, pp. 4115-4122
-
-
Ilangumaran, S.1
-
220
-
-
0042931134
-
Suppressor of cytokine signaling I regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes
-
Ilangumaran S, Ramanathan S, La Rose J, Poussier P, Rottapel R. Suppressor of cytokine signaling I regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes. J Immunol 2003;171:2435-2445.
-
(2003)
J Immunol
, vol.171
, pp. 2435-2445
-
-
Ilangumaran, S.1
Ramanathan, S.2
La Rose, J.3
Poussier, P.4
Rottapel, R.5
-
221
-
-
1442335020
-
A genome-wide survey of human tyrosine phosphatases
-
Bhaduri A, Sowdhamini R. A genome-wide survey of human tyrosine phosphatases. Protein Eng 2003;16:881-888.
-
(2003)
Protein Eng
, vol.16
, pp. 881-888
-
-
Bhaduri, A.1
Sowdhamini, R.2
-
222
-
-
0034096201
-
Protein phosphatases and the regulation of mitogen-activated protein kinase signalling
-
Keyse SM. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr Opin Cell Biol 2000;12:186-192.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 186-192
-
-
Keyse, S.M.1
-
223
-
-
18244411938
-
Long-term immune reconstitution and outcome after HLA-nonidentical T-cell-depleted bone marrow transplantation for severe combined immunodeficiency: A European retrospective study of 116 patients
-
Haddad E, et al. Long-term immune reconstitution and outcome after HLA-nonidentical T-cell-depleted bone marrow transplantation for severe combined immunodeficiency: a European retrospective study of 116 patients. Blood 1998;91:3646-3653.
-
(1998)
Blood
, vol.91
, pp. 3646-3653
-
-
Haddad, E.1
-
224
-
-
0033580206
-
Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency
-
Buckley RH, et al. Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. N Engl J Med 1999;340:508-516.
-
(1999)
N Engl J Med
, vol.340
, pp. 508-516
-
-
Buckley, R.H.1
-
225
-
-
0037129435
-
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
-
Hacein-Bey-Abina S, et al. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N Engl J Med 2002;346:1185-1193.
-
(2002)
N Engl J Med
, vol.346
, pp. 1185-1193
-
-
Hacein-Bey-Abina, S.1
-
226
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 2003;348:255-256.
-
(2003)
N Engl J Med
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
|