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Volumn 18, Issue , 2000, Pages 423-449

Regulatory T cells in autoimmmunity

Author keywords

Gastritis; Immune regulation; Organ specific autoimmunity; Suppressor T cells

Indexed keywords

CD4 ANTIGEN; TUMOR ANTIGEN;

EID: 0034084162     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.18.1.423     Document Type: Review
Times cited : (1183)

References (77)
  • 1
    • 0014792798 scopus 로고
    • Cell interactions in the induction of tolerance: The role of thymic lymphocytes
    • Gershon RK, Kondo K. 1970. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 18:723-35
    • (1970) Immunology , vol.18 , pp. 723-735
    • Gershon, R.K.1    Kondo, K.2
  • 2
    • 0027436739 scopus 로고
    • Saying the "S" word in public
    • Green DR, Webb DR. 1993. Saying the "S" word in public. Immunol. Today 14:523-25
    • (1993) Immunol. Today , vol.14 , pp. 523-525
    • Green, D.R.1    Webb, D.R.2
  • 3
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka Y, Sakakura T. 1969. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 166:753-55
    • (1969) Science , vol.166 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 5
    • 0018865212 scopus 로고
    • Experimental production of possible autoimmune gastritis followed by macrocytic anemia in athymic nude mice
    • Kojima A, Taguchi O, Nishizuka Y. 1980. Experimental production of possible autoimmune gastritis followed by macrocytic anemia in athymic nude mice. Lab. Invest. 42:387-95
    • (1980) Lab. Invest. , vol.42 , pp. 387-395
    • Kojima, A.1    Taguchi, O.2    Nishizuka, Y.3
  • 6
    • 0020432846 scopus 로고
    • Study on cellular events in post-thymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocyte damage after adoptive transfer
    • Sakaguchi S, Takahashi T, Nishizuka Y. 1982. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocyte damage after adoptive transfer. J. Exp. Med. 156:1565-76
    • (1982) J. Exp. Med. , vol.156 , pp. 1565-1576
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 7
    • 0020451946 scopus 로고
    • Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
    • Sakaguchi S, Takahashi T, Nishizuka Y. 1982. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J. Exp. Med. 156:1577-86
    • (1982) J. Exp. Med. , vol.156 , pp. 1577-1586
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 8
    • 0025949001 scopus 로고
    • Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy
    • Smith H, Sakamoto Y, Kasai K, Tung KSK. 1991. Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. J. Immunol. 147: 2928-33
    • (1991) J. Immunol. , vol.147 , pp. 2928-2933
    • Smith, H.1    Sakamoto, Y.2    Kasai, K.3    Tung, K.S.K.4
  • 9
    • 0026761052 scopus 로고
    • Tolerance mechanism in experimental ovarian and gastric autoimmune diseases
    • Smith H, Lou Y-H, Lacy P, Tung KSK. 1992. Tolerance mechanism in experimental ovarian and gastric autoimmune diseases. J. Immunol. 149:2212-18
    • (1992) J. Immunol. , vol.149 , pp. 2212-2218
    • Smith, H.1    Lou, Y.-H.2    Lacy, P.3    Tung, K.S.K.4
  • 10
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. 1985. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161:72-87
    • (1985) J. Exp. Med. , vol.161 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 11
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25)
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). J. Immunol. 155:1151-64
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 12
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consquence of developmental abnormality of a T cell subpopulation
    • Asano M, Toda M, Sakaguchi N, Sakaguchi S. 1996. Autoimmune disease as a consquence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184:387-96
    • (1996) J. Exp. Med. , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 13
    • 0031939403 scopus 로고    scopus 로고
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immuno-regulatory cells
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immuno-regulatory cells. J. Immunol. 160:1212-18
    • (1998) J. Immunol. , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 14
    • 0033064551 scopus 로고    scopus 로고
    • Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells
    • Suri-Payer E, Amar AZ, McHugh R, Natarajan K, Margulies DH, Shevach EM. 1999. Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells. Eur. J. Immunol. 29:669-77
    • (1999) Eur. J. Immunol. , vol.29 , pp. 669-677
    • Suri-Payer, E.1    Amar, A.Z.2    McHugh, R.3    Natarajan, K.4    Margulies, D.H.5    Shevach, E.M.6
  • 15
    • 0023917345 scopus 로고
    • Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice
    • Sakaguchi S, Sakaguchi N. 1988. Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice. J. Exp. Med. 167:1479-85
    • (1988) J. Exp. Med. , vol.167 , pp. 1479-1485
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 16
    • 0024589097 scopus 로고
    • Organ-specific autoimmune disease induced in mice by elimination of T cell subsets
    • Sakaguchi S, Sakaguchi N. 1989. Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. J. Immunol. 142:471-80
    • (1989) J. Immunol. , vol.142 , pp. 471-480
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 17
    • 0025062226 scopus 로고
    • Thymus and autoimmunity: Capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease
    • Sakaguchi S, Sakaguchi N. 1990. Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease. J. Exp. Med. 172:537-45
    • (1990) J. Exp. Med. , vol.172 , pp. 537-545
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 18
    • 0028348192 scopus 로고
    • Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells
    • Sakaguchi N, Miyai K, Sakaguchi S. 1994. Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells. J. Immunol. 152:2586-95
    • (1994) J. Immunol. , vol.152 , pp. 2586-2595
    • Sakaguchi, N.1    Miyai, K.2    Sakaguchi, S.3
  • 19
    • 0015908120 scopus 로고
    • Spontaneous thyroiditis in thymectomized and irradiated wistar rats
    • Penhale WJ, Farmer A, McKenna RP, Irvine WJ. 1973. Spontaneous thyroiditis in thymectomized and irradiated wistar rats. Clin. exp. Med. 15:225-36
    • (1973) Clin. Exp. Med. , vol.15 , pp. 225-236
    • Penhale, W.J.1    Farmer, A.2    McKenna, R.P.3    Irvine, W.J.4
  • 22
    • 0028944896 scopus 로고
    • Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia
    • Barrett SP, Toh BH, Alderuccio F, van Driel I, Gleeson PA. 1995. Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia. Eur. J. Immunol. 25:238-44
    • (1995) Eur. J. Immunol. , vol.25 , pp. 238-244
    • Barrett, S.P.1    Toh, B.H.2    Alderuccio, F.3    Van Driel, I.4    Gleeson, P.A.5
  • 23
    • 0029659052 scopus 로고    scopus 로고
    • Organ-specific autoimmunity induced by lymphopenia
    • Gleeson PA, Toh B-H, van Driel I. 1996. Organ-specific autoimmunity induced by lymphopenia. Immunol. Rev. 149:97-126
    • (1996) Immunol. Rev. , vol.149 , pp. 97-126
    • Gleeson, P.A.1    Toh, B.-H.2    Van Driel, I.3
  • 24
    • 0027220205 scopus 로고
    • An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus
    • Alderuccio F, Toh B-H, Tan S-S, Gleeson PA, van Driel IR. 1993. An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J. Exp. Med. 178:419-26
    • (1993) J. Exp. Med. , vol.178 , pp. 419-426
    • Alderuccio, F.1    Toh, B.-H.2    Tan, S.-S.3    Gleeson, P.A.4    Van Driel, I.R.5
  • 25
    • 0030760665 scopus 로고    scopus 로고
    • Expression of the gastric H/K-ATP-α-subunit in the thymus may explain the dominant role of the β-subunit in the pathogenesis of autoimmune gastritis
    • Alderuccio F, Gleeson PA, Berzins SP, Martin M, van Driel IR, Toh B-H. 1997. Expression of the gastric H/K-ATP-α-subunit in the thymus may explain the dominant role of the β-subunit in the pathogenesis of autoimmune gastritis. Autoimmunity 25:167-75
    • (1997) Autoimmunity , vol.25 , pp. 167-175
    • Alderuccio, F.1    Gleeson, P.A.2    Berzins, S.P.3    Martin, M.4    Van Driel, I.R.5    Toh, B.-H.6
  • 27
    • 0029084806 scopus 로고
    • Expression of a gastric autoantigen in pancreatic islets results in non-destructive insulitis after neonatal thymectomy
    • Barrett SP, van Driel IR, Tan S-S, Toh B-H, Gleeson PA. 1995. Expression of a gastric autoantigen in pancreatic islets results in non-destructive insulitis after neonatal thymectomy. Eur. J. Immunol. 25:2686-94
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2686-2694
    • Barrett, S.P.1    Van Driel, I.R.2    Tan, S.-S.3    Toh, B.-H.4    Gleeson, P.A.5
  • 28
    • 0016764764 scopus 로고
    • Thyroiditis in T cell-depleted rats: Influence of strain, radiation dose, adjuvants and antilymphocyte serum
    • Penhale WJ, Farmer A, Irvine WJ. 1975. Thyroiditis in T cell-depleted rats: influence of strain, radiation dose, adjuvants and antilymphocyte serum. Clin. exp. Immunol. 21:362-75
    • (1975) Clin. Exp. Immunol. , vol.21 , pp. 362-375
    • Penhale, W.J.1    Farmer, A.2    Irvine, W.J.3
  • 29
    • 0017195863 scopus 로고
    • Thyroiditis in T cell-depleted rats: Suppression of the autoallergic response by reconstitution with normal lymphoid cells
    • Penhale WJ, Irvine WJ, Inglis JR, Farmer A. 1976. Thyroiditis in T cell-depleted rats: suppression of the autoallergic response by reconstitution with normal lymphoid cells. Clin. Exp. Immunol. 25:6-16
    • (1976) Clin. Exp. Immunol. , vol.25 , pp. 6-16
    • Penhale, W.J.1    Irvine, W.J.2    Inglis, J.R.3    Farmer, A.4
  • 32
    • 0027509812 scopus 로고
    • + T cell subset that inhibits this autoimmune potential
    • + T cell subset that inhibits this autoimmune potential. J. Exp. Med. 177:627-36
    • (1993) J. Exp. Med. , vol.177 , pp. 627-636
    • Fowell, D.1    Mason, D.2
  • 33
    • 0028179230 scopus 로고
    • + T cells are important for the balance between protective and pathogenic cell-mediated immunity
    • + T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179:589-600
    • (1994) J. Exp. Med. , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.L.4
  • 38
    • 0033560023 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-12 receptor subunit expression by endogneous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells
    • Chang JT, Shevach EM, Segal BM. 1999. Regulation of interleukin (IL)-12 receptor subunit expression by endogneous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells. J. Exp. Med. 189:969-78
    • (1999) J. Exp. Med. , vol.189 , pp. 969-978
    • Chang, J.T.1    Shevach, E.M.2    Segal, B.M.3
  • 41
    • 0019442054 scopus 로고
    • Experimental autoimmune orchitis after neonatal thymectomy in the mouse
    • Taguchi O, Nishizuka Y. 1981. Experimental autoimmune orchitis after neonatal thymectomy in the mouse. Clin. exp. Immunol. 46:425-34
    • (1981) Clin. Exp. Immunol. , vol.46 , pp. 425-434
    • Taguchi, O.1    Nishizuka, Y.2
  • 42
    • 0023155686 scopus 로고
    • Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance
    • Taguchi O, Nishizuka Y. 1987. Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance. J. Exp. Med 165:146-56
    • (1987) J. Exp. Med , vol.165 , pp. 146-156
    • Taguchi, O.1    Nishizuka, Y.2
  • 43
    • 0028103905 scopus 로고
    • Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigens
    • Taguchi O, Kontani K, Ikeda H, Kezuka T, Takeuchi M, Takahashi T. 1994. Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigens. Immunology 82:365-69
    • (1994) Immunology , vol.82 , pp. 365-369
    • Taguchi, O.1    Kontani, K.2    Ikeda, H.3    Kezuka, T.4    Takeuchi, M.5    Takahashi, T.6
  • 44
    • 0029659054 scopus 로고    scopus 로고
    • The significance of immune suppression in normal self tolerance
    • McCullagh P. 1996. The significance of immune suppression in normal self tolerance. Immunol. Rev. 149:127-54
    • (1996) Immunol. Rev. , vol.149 , pp. 127-154
    • McCullagh, P.1
  • 45
    • 0033103668 scopus 로고    scopus 로고
    • Peripheral autoantigen induces regulatory T cells that prevent autoimmunity
    • Seddon B, Mason D. 1999. Peripheral autoantigen induces regulatory T cells that prevent autoimmunity. J. Exp. Med. 189:877-81
    • (1999) J. Exp. Med. , vol.189 , pp. 877-881
    • Seddon, B.1    Mason, D.2
  • 46
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287-96
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 48
    • 0342634833 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+ CD25+ immunoregulatory T cells is antigen non-specific
    • In press
    • Thornton AM, Shevach EM. 1999. Suppressor effector function of CD4+ CD25+ immunoregulatory T cells is antigen non-specific. J. Immunol. In press
    • (1999) J. Immunol.
    • Thornton, A.M.1    Shevach, E.M.2
  • 50
    • 0024500755 scopus 로고
    • T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
    • Boitard C, Yasunami R, Dardenne M, Bach JF. 1989. T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J. Exp. Med. 169:1669-80
    • (1989) J. Exp. Med. , vol.169 , pp. 1669-1680
    • Boitard, C.1    Yasunami, R.2    Dardenne, M.3    Bach, J.F.4
  • 51
    • 0025115596 scopus 로고
    • The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males
    • Hutchings PR, Cooke A. 1990. The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males. J. Autoimmun. 3:175-85
    • (1990) J. Autoimmun. , vol.3 , pp. 175-185
    • Hutchings, P.R.1    Cooke, A.2
  • 55
    • 0030175335 scopus 로고    scopus 로고
    • + suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice
    • + suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice. J. Autoimmun. 9:331-39
    • (1996) J. Autoimmun. , vol.9 , pp. 331-339
    • Han, H.-S.1    Jun, H.-S.2    Utsugi, T.3    Yoon, J.-W.4
  • 56
    • 0025911147 scopus 로고
    • Islet-infiltrating T cell clones from non-obese diabetic mice that promote or prevent accelerated onset diabetes
    • Pankewycz O, Strom TB, Rubin-Kelley VE. 1991. Islet-infiltrating T cell clones from non-obese diabetic mice that promote or prevent accelerated onset diabetes. Eur. J. Immunol. 21:873-79
    • (1991) Eur. J. Immunol. , vol.21 , pp. 873-879
    • Pankewycz, O.1    Strom, T.B.2    Rubin-Kelley, V.E.3
  • 58
  • 60
    • 0032538918 scopus 로고    scopus 로고
    • + T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    • + T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J. Exp. Med. 188:1883-94
    • (1998) J. Exp. Med. , vol.188 , pp. 1883-1894
    • Olivares-Villagomez, D.1    Wang, Y.2    Lafaille, J.J.3
  • 61
    • 0032538820 scopus 로고    scopus 로고
    • + cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice
    • + cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice. J. Exp. Med. 10:1875-82
    • (1998) J. Exp. Med. , vol.10 , pp. 1875-1882
    • Van De Keere, F.1    Tonegawa, S.2
  • 62
    • 2642654250 scopus 로고    scopus 로고
    • Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities
    • Luhder F, Katz J, Benoist C, Mathis D. 1998. Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. J. Exp. Med. 187:379-87
    • (1998) J. Exp. Med. , vol.187 , pp. 379-387
    • Luhder, F.1    Katz, J.2    Benoist, C.3    Mathis, D.4
  • 63
    • 0030442723 scopus 로고    scopus 로고
    • The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients
    • Saoudi A, Seddon B, Fowell D, Mason D. 1996. The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients. J. Exp. Med. 184:2393-98
    • (1996) J. Exp. Med. , vol.184 , pp. 2393-2398
    • Saoudi, A.1    Seddon, B.2    Fowell, D.3    Mason, D.4
  • 64
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: Expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik M, Leite de Moraes M, Pontoux C, Vasseur F, Penit C. 1998. Regulatory CD4 T cells: expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10:371-78
    • (1998) Int. Immunol. , vol.10 , pp. 371-378
    • Papiernik, M.1    Leite De Moraes, M.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 66
    • 0029835390 scopus 로고    scopus 로고
    • Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
    • Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383:81-85
    • (1996) Nature , vol.383 , pp. 81-85
    • Laufer, T.M.1    DeKoning, J.2    Markowitz, J.S.3    Lo, D.4    Glimcher, L.H.5
  • 67
    • 0033136289 scopus 로고    scopus 로고
    • Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
    • Laufer TM, Fan L, Glimcher LH. 1999. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J. Immunol. 162: 5078-84
    • (1999) J. Immunol. , vol.162 , pp. 5078-5084
    • Laufer, T.M.1    Fan, L.2    Glimcher, L.H.3
  • 68
    • 0030848546 scopus 로고    scopus 로고
    • Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides
    • Grubin CE, Kovats S, deRoos P, Rudensky AY. 1997. Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity 7:197-208
    • (1997) Immunity , vol.7 , pp. 197-208
    • Grubin, C.E.1    Kovats, S.2    DeRoos, P.3    Rudensky, A.Y.4
  • 69
    • 0030073402 scopus 로고    scopus 로고
    • A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens
    • Modigliani Y, Bandeira A, Coutinho A. 1996. A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens. Immunol. Rev. 149:155-74
    • (1996) Immunol. Rev. , vol.149 , pp. 155-174
    • Modigliani, Y.1    Bandeira, A.2    Coutinho, A.3
  • 71
    • 0032433125 scopus 로고    scopus 로고
    • Analysis of the role of variations of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response
    • Ridgway WM, Ito H, Fasso M, Yu C, Fathman CG. 1998. Analysis of the role of variations of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response. J. Exp. Med. 188:2267-75
    • (1998) J. Exp. Med. , vol.188 , pp. 2267-2275
    • Ridgway, W.M.1    Ito, H.2    Fasso, M.3    Yu, C.4    Fathman, C.G.5
  • 72
    • 0032526853 scopus 로고    scopus 로고
    • Endogenous myelin basic protein inactivates the high avidity T cell repertoire
    • Targoni OS, Lehmann PV. 1998. Endogenous myelin basic protein inactivates the high avidity T cell repertoire. J. Exp. Med. 187:2055-63
    • (1998) J. Exp. Med. , vol.187 , pp. 2055-2063
    • Targoni, O.S.1    Lehmann, P.V.2
  • 74
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology
    • Sloan-Lancaster J, Allen PM. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1-27
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 1-27
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 76
    • 0029955719 scopus 로고    scopus 로고
    • T cell-mediated maintenance of natural self-tolerance: Its breakdown as a possible cause of various autoimmune diseases
    • Sakaguchi S, Toda M, Asano M, Itoh M, Morse SS, Sakaguchi N. 1996. T cell-mediated maintenance of natural self-tolerance: its breakdown as a possible cause of various autoimmune diseases. J. Autoimmun. 9:211-20
    • (1996) J. Autoimmun. , vol.9 , pp. 211-220
    • Sakaguchi, S.1    Toda, M.2    Asano, M.3    Itoh, M.4    Morse, S.S.5    Sakaguchi, N.6
  • 77
    • 0023858264 scopus 로고
    • Do suppressor T cells exist?
    • Moller G. 1988. Do suppressor T cells exist? Scand. J. Immunol. 27:247-50
    • (1988) Scand. J. Immunol. , vol.27 , pp. 247-250
    • Moller, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.