-
2
-
-
0028845212
-
Cytokine receptor signalling
-
(1995)
Nature
, vol.377
, pp. 591-594
-
-
Ihle, J.N.1
-
6
-
-
0034658583
-
Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
-
(2000)
Oncogene
, vol.19
, pp. 2557-2565
-
-
Kotenko, S.V.1
Pestka, S.2
-
9
-
-
17744373448
-
Interleukin 20. Discovery, receptor identification, and role in epidermal function
-
(2001)
Cell
, vol.104
, pp. 9-19
-
-
Blumberg, H.1
Conklin, D.2
Xu, W.3
Grossmann, A.4
Brender, T.5
Carollo, S.6
Eagan, M.7
Foster, D.8
Haldeman, B.A.9
Hammond, A.10
-
10
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
-
11
-
-
0034232353
-
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin
-
(2000)
Nat Immunol
, vol.1
, pp. 59-64
-
-
Pandey, A.1
Ozaki, K.2
Baumann, H.3
Levin, S.D.4
Puel, A.5
Farr, A.G.6
Ziegler, S.F.7
Leonard, W.J.8
Lodish, H.F.9
-
12
-
-
0033965488
-
Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: Evidence for interactions between the kinase and pseudokinase domains
-
(2000)
Mol Cell Biol
, vol.20
, pp. 947-956
-
-
Chen, M.1
Cheng, A.2
Candotti, F.3
Zhou, Y.J.4
Hymel, A.5
Fasth, A.6
Notarangelo, L.D.7
O'Shea, J.J.8
-
17
-
-
0033559793
-
Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3-receptor interaction domain
-
(1999)
EMBO J
, vol.18
, pp. 1549-1558
-
-
Cacalano, N.A.1
Migone, T.S.2
Bazan, F.3
Hanson, E.P.4
Chen, M.5
Candotti, F.6
O'Shea, J.J.7
Johnston, J.A.8
-
18
-
-
0034501027
-
Of genes and phenotypes: The immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model
-
(2000)
Immunol Rev
, vol.178
, pp. 39-48
-
-
Notarangelo, L.D.1
Giliani, S.2
Mazza, C.3
Mella, P.4
Savoldi, G.5
Rodriguez-Perez, C.6
Mazzolari, E.7
Fiorini, M.8
Duse, M.9
Plebani, A.10
-
20
-
-
0033952813
-
Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma[c])-dependent signaling: Comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice
-
(2000)
Int Immunol
, vol.12
, pp. 123-132
-
-
Suzuki, K.1
Nakajima, H.2
Saito, Y.3
Saito, T.4
Leonard, W.J.5
Iwamoto, I.6
-
21
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
-
(2000)
J Exp Med
, vol.191
, pp. 771-780
-
-
Kennedy, M.K.1
Glaccum, M.2
Brown, S.N.3
Butz, E.A.4
Viney, J.L.5
Embers, M.6
Matsuki, N.7
Charrier, K.8
Sedger, L.9
Willis, C.R.10
-
24
-
-
0035159241
-
Jak3 selectively regulates bax and bcl-2 expression To promote T-cell development
-
(2001)
Mol Cell Biol
, vol.21
, pp. 678-689
-
-
Wen, R.1
Wang, D.2
McKay, C.3
Bunting, K.D.4
Marine, J.C.5
Vanin, E.F.6
Zambetti, G.P.7
Korsmeyer, S.J.8
Ihle, J.N.9
Cleveland, J.L.10
-
26
-
-
0033199317
-
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
-
(1999)
Immunity
, vol.11
, pp. 281-288
-
-
Van Parijs, L.1
Refaeli, Y.2
Lord, J.D.3
Nelson, B.H.4
Abbas, A.K.5
Baltimore, D.6
-
27
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
Hammond, A.4
Sprecher, C.5
Gross, J.A.6
Johnston, J.7
Madden, K.8
Xu, W.9
West, J.10
-
28
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
McKay, C.2
Wang, D.3
Topham, D.J.4
Parganas, E.5
Nakajima, H.6
Pendeville, H.7
Yasukawa, H.8
Sasaki, A.9
Yoshimura, A.10
Ihle, J.N.11
-
29
-
-
0033711641
-
Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function
-
(2000)
Immunity
, vol.13
, pp. 561-571
-
-
Shimoda, K.1
Kato, K.2
Aoki, K.3
Matsuda, T.4
Miyamoto, A.5
Shibamori, M.6
Yamashita, M.7
Numata, A.8
Takase, K.9
Kobayashi, S.10
-
30
-
-
0033696404
-
Partial impairment of cytokine responses in Tyk2-deficient mice
-
(2000)
Immunity
, vol.13
, pp. 549-560
-
-
Karaghiosoff, M.1
Neubauer, H.2
Lassnig, C.3
Kovarik, P.4
Schindler, H.5
Pircher, H.6
McCoy, B.7
Bogdan, C.8
Decker, T.9
Brem, G.10
-
31
-
-
0034658541
-
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
-
(2000)
Oncogene
, vol.19
, pp. 2548-2556
-
-
Hirano, T.1
Ishihara, K.2
Hibi, M.3
-
40
-
-
0035862950
-
Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
-
(2001)
EMBO J
, vol.20
, pp. 91-100
-
-
Kovarik, P.1
Mangold, M.2
Ramsauer, K.3
Heidari, H.4
Steinborn, R.5
Zotter, A.6
Levy, D.E.7
Muller, M.8
Decker, T.9
-
47
-
-
0032561211
-
Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation
-
(1998)
J Biol Chem
, vol.273
, pp. 28049-28056
-
-
Strehlow, I.1
Schindler, C.2
-
54
-
-
0034657958
-
Roles of STAT3 defined by tissue-specific gene targeting
-
(2000)
Oncogene
, vol.19
, pp. 2607-2611
-
-
Akira, S.1
-
62
-
-
18144438839
-
Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
-
(2000)
J Immunol
, vol.164
, pp. 4659-4664
-
-
Frucht, D.M.1
Aringer, M.2
Galon, J.3
Danning, C.4
Brown, M.5
Fan, S.6
Centola, M.7
Wu, C.Y.8
Yamada, N.9
El Gabalawy, H.10
O'Shea, J.J.11
-
64
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
McKay, C.2
Schuetz, E.3
Van Deursen, J.M.4
Stravopodis, D.5
Wang, D.6
Brown, M.7
Bodner, S.8
Grosveld, G.9
Ihle, J.N.10
-
65
-
-
0033082138
-
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
-
(1999)
Immunity
, vol.10
, pp. 249-259
-
-
Moriggl, R.1
Topham, D.J.2
Teglund, S.3
Sexl, V.4
McKay, C.5
Wang, D.6
Hoffmeyer, A.7
Van Deursen, J.8
Sangster, M.Y.9
Bunting, K.D.10
-
66
-
-
0033639119
-
Stat5 is essential for the myelo- and lympho-proliferative disease induced by TEL/JAK2
-
(2000)
Mol Cell
, vol.6
, pp. 693-704
-
-
Schwaller, J.1
Parganas, E.2
Wang, D.3
Cain, D.4
Aster, J.C.5
Williams, I.R.6
Lee, C.K.7
Gerthner, R.8
Kitamura, T.9
Frantsve, J.10
-
67
-
-
0032926518
-
+ T cells
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 114-123
-
-
Miyata, S.1
Matsuyama, T.2
Kodama, T.3
Nishioka, Y.4
Kuribayashi, K.5
Takeda, K.6
Akira, S.7
Sugita, M.8
-
73
-
-
13144258732
-
Twenty proteins containing a C-terminal SOCS box form five structural classes
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 114-119
-
-
Hilton, D.J.1
Richardson, R.T.2
Alexander, W.S.3
Viney, E.M.4
Willson, T.A.5
Sprigg, N.S.6
Starr, R.7
Nicholson, S.E.8
Metcalf, D.9
Nicola, N.A.10
-
74
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2071-2076
-
-
Zhang, J.G.1
Farley, A.2
Nicholson, S.E.3
Willson, T.A.4
Zugaro, L.M.5
Simpson, R.J.6
Moritz, R.L.7
Cary, D.8
Richardson, R.9
Hausmann, G.10
-
75
-
-
0032772125
-
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6396-6407
-
-
Matsumoto, A.1
Seki, Y.2
Kubo, M.3
Ohtsuka, S.4
Suzuki, A.5
Hayashi, I.6
Tsuji, K.7
Nakahata, T.8
Okabe, M.9
Yamada, S.10
Yoshimura, A.11
-
76
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
(1999)
EMBO J
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
Ohtsuka, S.7
Imaizumi, T.8
Matsuda, T.9
Ihle, J.N.10
Yoshimura, A.11
-
77
-
-
0033555258
-
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction
-
(1999)
EMBO J
, vol.18
, pp. 375-385
-
-
Nicholson, S.E.1
Willson, T.A.2
Farley, A.3
Starr, R.4
Zhang, J.G.5
Baca, M.6
Alexander, W.S.7
Metcalf, D.8
Hilton, D.J.9
Nicola, N.A.10
-
78
-
-
0032573161
-
Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13130-13134
-
-
Narazaki, M.1
Fujimoto, M.2
Matsumoto, T.3
Morita, Y.4
Saito, H.5
Kajita, T.6
Yoshizaki, K.7
Naka, T.8
Kishimoto, T.9
-
79
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
80
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
-
81
-
-
0034729710
-
Gigantism in mice lacking suppressor of cytokine signalling-2
-
(2000)
Nature
, vol.405
, pp. 1069-1073
-
-
Metcalf, D.1
Greenhalgh, C.J.2
Viney, E.3
Willson, T.A.4
Starr, R.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
85
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6493-6498
-
-
Nicholson, S.E.1
De, S.D.2
Fabri, L.J.3
Corbin, J.4
Willson, T.A.5
Zhang, J.G.6
Silva, A.7
Asimakis, M.8
Farley, A.9
Nash, A.D.10
-
89
-
-
0034657917
-
Modulation of STAT signaling by STAT-interacting proteins
-
(2000)
Oncogene
, vol.19
, pp. 2638-2644
-
-
Shuai, K.1
-
94
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
(2001)
Nature
, vol.409
, pp. 349-354
-
-
Irie-Sasaki, J.1
Sasaki, T.2
Matsumoto, W.3
Opavsky, A.4
Cheng, M.5
Welstead, G.6
Griffiths, E.7
Krawczyk, C.8
Richardson, C.D.9
Aitken, K.10
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