Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon γ-producing Th1 cells

Journal of Experimental Medicine

Volumn 196, Issue 7, 2002, Pages 969-977

  Wurster, Andrea L ^a   Rodgers, Vikki L ^a   Satoskar, Abhay R ^b   Whitters, Matthew J ^c   Young, Deborah A ^c   Collins, Mary ^c   Grusby, Michael J ^a,d  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c PFIZER INC   (United States)

^d Dept of Immunology and Infectious Diseases ^*  (United States)

Author keywords

Cell differentiation; Cytokines; Immunosuppression; Interleukins; T lymphocytes helper inducer

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 21; MESSENGER RNA; STAT4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; GENE EXPRESSION; HELPER CELL; IMMUNE RESPONSE; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CELL DIFFERENTIATION; CYTOKINES; INTERFERON TYPE II; INTERLEUKINS; MICE; MICE, INBRED C57BL; T-LYMPHOCYTES, HELPER-INDUCER; TH1 CELLS;

EID: 0037037544     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020620     Document Type: Article

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