Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain

Journal of Experimental Medicine

Volumn 185, Issue 3, 1997, Pages 499-505

  Suzuki, Haruhiko ^a,c   Duncan, Gordon S ^a   Takimoto, Hiroaki ^a,d   Mak, Tak W ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b AMGEN INSTITUTE   (Canada)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; INTESTINE EPITHELIUM CELL; LYMPHOCYTE SUBPOPULATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CYTOTOXICITY, IMMUNOLOGIC; INTERLEUKIN-15; INTERLEUKIN-2; INTESTINES; KILLER CELLS, NATURAL; LYMPHOCYTES; MICE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, INTERLEUKIN-2;

EID: 0031051547     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.3.499     Document Type: Article

References (43)

1. Waldmann, T.A. 1993. The IL-2/IL-2 receptor system: a target for rational immune intervention. Immunol. Today. 14: 264-270.
2. Begley, C.G., J.D. Burton, M. Tsudo, B.H. Brownstein, J.L. Ambrus, and T.A. Waldmann. 1990. Human β lymphocytes express the p75 component of the interleukin 2 receptor. Leuk. Res. 14:263-271.
3. Nishikawa, K., S. Saito, T. Mori, Y. Kato, N. Narita, M. Ichijo, Y. Ohashi, T. Takeshita, and K. Sugamura. 1990. Differential expression of the interleukin 2 receptor beta (p75) chain on human peripheral blood natural killer subsets. Int. Immunol. 2:481-486.
4. Djeu, J.Y., J.H. Liu, S. Wei, H. Rui, C.A. Pearson, W.J. Leonard, and D.K. Blanchard. 1993. Function associated with IL-2 receptor-beta on human neutrophils. Mechanism of activation of antifungal activity against Candida albicans by IL-2. J. Immunol. 150:960-970.
5. Espinoza-Delgado, I., J.R. Ortaldo, R. Winkler-Pickett, K. Sugamura, L. Varesio, and D.L. Longo. 1990. Expression and role of p75 interleukin 2 receptor on human monocytes. J. Exp. Med. 171:1821-1826.
6. Minami, Y., T. Kono, T. Miyazaki, and T. Taniguchi. 1993. The IL-2 receptor complex: its structure, function, and target genes. Annu. Rev. Immunol. 11:245-268.
7. Taniguchi, T., and Y. Minami. 1993. The IL-2/IL-2 receptor system: a current overview. Cell. 73:5-8.
8. Grabstein, K.H., J. Eisenman, K. Shanebeck, C. Rauch, S. Srinivasan, V. Fung, C. Beers, J. Richardson, M.A. Schoenbom, M. Ahdieh et al. 1994. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor. Science (Wash. DC). 264:965-968.
9. Willerford, D.M., J. Chen, J.A. Ferry, L. Davidson, A. Ma, and F.W. Alt. 1995. Interleukin-2 receptor a chain regulates the size and content of the peripheral lymphoid compartment. Immunity. 3:521-530.
10. Suzuki, H., T.M. Kündig, C. Furlonger, A. Wakeham, E. Timms, T. Matsuyama, R. Schmits, J.J.L. Simard, P.S. Ohashi, H. Griesser et al. 1995. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β. Science (Wash. DC). 268:1472-1476.
11. DiSanto, J.P., W. Müller, D. Guy-Grand, A. Fischer, and K. Rajewsky. 1995. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl. Acad. Sci. USA. 92:377-381.
12. Noguchi, M., H. Yi, H.M. Rosenblatt, A.H. Filipovich, S. Adelstein, W.S. Modi, O.W. McBride, and W.J. Leonard. 1993. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell. 73:147-157.
13. Conley, M.E. 1992. Molecular approaches to the analysis of X-linked immunodeficiencies. Annu. Rev. Immunol. 10: 215-238.
14. Carson, W.E., J.G. Giri, M.J. Lindenmann, M.L. Linett, M. Ahdieh, R. Paxton, D. Anderson, J. Eisenmann, K. Grabstein, and M.A. Caliguri. 1994. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J. Exp. Med. 180:1395-1403.
15. + intraepithelial lymphocyte T cells abrogate oral tolerance. J. Immunol. 145:2010-2019.
16. Poussier, P., and M. Julius. 1994. Thymus independent T cell development and selection in the intestinal epithelium. Annu. Rev. Immunol. 12:521-553.
17. Poussier, P., and M. Julius. 1994. Intestinal intraepithelial lymphocytes: the plot thickens. J. Exp. Med. 180:1185-1189.
18. Rocha, B., D. Guy-Grand, and P. Vassalli. 1995. Extrathymic T cell differentiation. Curr. Opin. Immunol. 7:235-242.
19. Kawamoto, Y., K. Sasaki, Y. Kato, K. Kojima, T. Tsuji, and A. Miyama. 1996. Rapid killing of murine lymph node T blasts by intestinal intraepithelial lymphocytes in vitro. Eur. J. Immunol. 26:653-658.
20. Ohtsuka, K., T. Iiai, H. Watanabe, T. Tanaka, M. Miyasaka, K. Sato, H. Asakura, and T. Abo. 1994. Similarities and differences between extrathymic T cells residing in mouse liver and intestine. Cell. Immunol. 153:52-66.
21. + T cells, but not natural killer cells. J. Exp. Med. 184:289-293.
22. Maki, K., S. Sunaga, Y. Komagata, Y. Kodaira, A. Mabuchi, H. Karasuyama, K. Yokomuro, J.-I. Miyazaki, and K. Ikuta. 1996. Interleukin 7 receptor-deficient mice lack γδ T cells. Proc. Natl. Acad. Sci. USA. 93:7172-7177.
23. Guy-Grand, D., B. Rocha, P. Mintz, M. Malassis-Seris, F. Selz, B. Malissen, and P. Vasalli. 1994. Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J. Exp. Med. 180:673-679.
24. Rocha, B., P. Vassalli, and D. Guy-Grand. 1994. Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice. J. Exp. Med. 180:681-686.
25. Trinchierei, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187-386.
26. Phillips, J.H., T. Takeshita, K. Sugamura, and L.L. Lanier. 1989. Activation of natural killer cells via the p75 interleukin 2 receptor J. Exp. Med. 170:291-296.
27. Tanaka, T., F. Kitamura, Y. Nagasaka, K. Kuida, H. Suwa, and M. Miyasaka. 1993. Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor β chain monoclonal antibody in mice. J. Exp. Med. 178:1103-1107.
28. Giorda, R., E.P. Weisberg, T.K. Ip, and M. Trucco. 1992. Genomic structure and strain-specific expression of the natural killer receptor NKR-P1. J. Immunol. 149:1631-1635.
29. Yokoyama, W.M., and W.E. Seaman. 1993. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu. Rev. Immunol. 11:613-635.
30. Malek, T.R., V. Vincek, B. Gatalica, and M. Bucan. 1993. The IL-2 receptor beta chain gene (IL-2Rβ) is closely linked to the PDGFβ locus on mouse chromosome 15. Immunogenetics. 38:154-156.
31. Rodewald, H.R., P. Moingeon, J.L. Lucich, C. Dosion, P. Lopez, and E.L. Reinherz. 1992. A population of early fetal thymocytes expressing FcγRII/III contain precursors of T lymphocytes and natural killer cells. Cell. 69:139-150.
32. Sanchez, M.J., M.O. Muench, M.G. Roncarolo, L.L. Lanier, and J.H. Phillips. 1994. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180:569-576.
33. Sanchez, M.J., H. Spits, L.L. Lanier, and J.H. Phillips. 1993. Human natural killer cell committed thymocytes and their relation to the T cell lineage. J. Exp. Med. 178:1857-1866.
34. Leclerque, G., V. Debacker, M. DeSmedt, and J. Plum. 1996. Differential effects of interleukin-15 and interleukin-2 on differentiation of bi-potential T/natural killer progenitor cells. J. Exp. Med. 184:325-226.
35. Falk, I., C.N. Levelt, and K. Eichmann. 1993. Lineage relationships of the fetal thymocyte subset that expresses the β chain of the interleukin-2 receptor. Eur. J. Immunol. 23: 3373-3376.
36. Kundig, T.M., H. Schorle, M.F. Bachmann, H. Hengartner, R.M. Zinkernagel, and I. Horak. 1993. Immune responses in interleukin-2-deficient mice. Science (Wash. DC). 262:1059-1061.
37. Puzanov, I.J., M. Bennett, and V. Kumar. 1996. IL-15 can substitute for the marrow microenvironment in the differentiation of natural killer cells. J. Immunol. 157:4282-4285.
38. + dendritic epidermal cells. Int. Immunol. 4:487-191.
39. + dendritic epidermal cells of adult mice from fetal thymic precursors. Nature (Lod.). 344:68-70.
40. Schimpl, A., T. Hünig, A. Elbe, I. Berberich, S. Krämer, H. Merz, A.C. Feller, B. Sadlack, H. Schorle, and I. Horak. 1994. Development and function of the immune system in mice with targeted disruption of the IL-2 gene. In Transgenics and Targeted Mutagenesis in Immunology. H. Bluethman and P. Ohasi, editors. Academic Press, London, UK. 191-201.
41. Rocha, B., P. Vassalli, and D. Guy-Grand. 1992. The extrathymic T-cell development pathway. Immunol. Today. 13: 449-454.
42. Guy-Grand, D., B. Cuenod-Jabri, M. Malassis-Seris, F. Selz, and P. Vassalli. 1996. Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur. J. Immunol. 26:2248-2256.
43. Giri, J.G., S. Kumaki, M. Ahdieh, D.J. Friend, A. Loomis, K. Shanebeck, R. DuBose, D. Cosman, L.S. Park, and D.M. Anderson. 1995. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO (Eur. Mol. Biol. Organ.) J. 14: 3654-3663.