Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells

Journal of Experimental Medicine

Volumn 193, Issue 2, 2001, Pages 219-231

  Fehniger, Todd A ^a,b   Suzuki, Kazuhiro ^a,c   Ponnappan, Anand ^a   VanDeusen, Jeffrey B ^a,b   Cooper, Megan A ^a,b   Florea, Sorin M ^a   Freud, Aharon G ^a   Robinson, Michael L ^d   Durbin, Joan ^d   Caligiuri, Michael A ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c GUNMA UNIVERSITY   (Japan)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

Inflammation; Interleukin 15; Leukemia; Lymphocytes; Transgenic mice

Indexed keywords

CD8 ANTIGEN; INTERLEUKIN 15;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE STRUCTURE; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; LYMPHATIC LEUKEMIA; MEMORY CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; DNA PRIMERS; GENETIC ENGINEERING; IMMUNOLOGIC MEMORY; INFLAMMATION MEDIATORS; INTERLEUKIN-15; KILLER CELLS, NATURAL; LEUKEMIA, EXPERIMENTAL; LYMPHOCYTOSIS; MICE; MICE, TRANSGENIC; PHENOTYPE; TIME FACTORS;

EID: 0035862325     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.2.219     Document Type: Article

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