메뉴 건너뛰기




Volumn 39, Issue 9, 2002, Pages 537-544

Interleukin-15 and the regulation of lymphoid homeostasis

Author keywords

Interleukin 15; Lymphoid homeostasis; Pleiotropic expression

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 2; RECEPTOR SUBTYPE;

EID: 0036890419     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(02)00211-0     Document Type: Review
Times cited : (61)

References (68)
  • 1
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:2001;675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 2
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L., Holt A.C., Medzhitov R., Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 413:2001;732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 3
    • 0034812784 scopus 로고    scopus 로고
    • Differential effects of IL-2 and IL-15 on expression of IL-2 receptor alpha
    • Alileche A., Goldman C.K., Waldmann T.A. Differential effects of IL-2 and IL-15 on expression of IL-2 receptor alpha. Biochem. Biophys. Res. Commun. 285:2001;1302-1308.
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 1302-1308
    • Alileche, A.1    Goldman, C.K.2    Waldmann, T.A.3
  • 5
    • 0033854469 scopus 로고    scopus 로고
    • Viral activation of interleukin-15 (IL-15): Characterization of a virus-inducible element in the IL-15 promoter region
    • Azimi N., Tagaya Y., Mariner J., Waldmann T.A. Viral activation of interleukin-15 (IL-15): characterization of a virus-inducible element in the IL-15 promoter region. J. Virol. 74:2000;7338-7348.
    • (2000) J. Virol. , vol.74 , pp. 7338-7348
    • Azimi, N.1    Tagaya, Y.2    Mariner, J.3    Waldmann, T.A.4
  • 6
    • 0030008255 scopus 로고    scopus 로고
    • Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region/IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation
    • Bamford R.N., Baffiata A.P., Burton J.D., Sharma H., Waldmann T.A. Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region/IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation. Proc. Natl. Acad. Sci. U.S.A. 93:1996;2897-2902.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 2897-2902
    • Bamford, R.N.1    Baffiata, A.P.2    Burton, J.D.3    Sharma, H.4    Waldmann, T.A.5
  • 7
    • 0032080666 scopus 로고    scopus 로고
    • The 5′-untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control
    • Bamford R.N., DeFilippis A.P., Azimi N., Kurys G., Waldmann T.A. The 5′-untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control. J. Immunol. 160:1998;4418-4426.
    • (1998) J. Immunol. , vol.160 , pp. 4418-4426
    • Bamford, R.N.1    DeFilippis, A.P.2    Azimi, N.3    Kurys, G.4    Waldmann, T.A.5
  • 8
    • 0028363377 scopus 로고
    • The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
    • Bamford R.N., Grant A.J., Burton J.D., Peters C., Kurys G., Goldman C.K., Brennan J., Roessler E., Waldmann T.A. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc. Natl. Acad. Sci. U.S.A. 91:1994;4940-4944.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4940-4944
    • Bamford, R.N.1    Grant, A.J.2    Burton, J.D.3    Peters, C.4    Kurys, G.5    Goldman, C.K.6    Brennan, J.7    Roessler, E.8    Waldmann, T.A.9
  • 9
    • 0023200330 scopus 로고
    • The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells
    • Bell E.B., Sparshott S.M., Drayson M.T., Ford W.L. The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells. J. Immunol. 139:1987;1379-1384.
    • (1987) J. Immunol. , vol.139 , pp. 1379-1384
    • Bell, E.B.1    Sparshott, S.M.2    Drayson, M.T.3    Ford, W.L.4
  • 12
    • 0034698828 scopus 로고    scopus 로고
    • Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells
    • Cho B.K., Rao V.P., Ge Q., Eisen H.N., Chen J. Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J. Exp. Med. 192:2000;549-556.
    • (2000) J. Exp. Med. , vol.192 , pp. 549-556
    • Cho, B.K.1    Rao, V.P.2    Ge, Q.3    Eisen, H.N.4    Chen, J.5
  • 13
    • 0031194890 scopus 로고    scopus 로고
    • Cytokines: Shared receptors, distinct functions
    • DiSanto J.P. Cytokines: shared receptors, distinct functions. Curr. Biol. 7:1997;R424-R426.
    • (1997) Curr. Biol. , vol.7
    • DiSanto, J.P.1
  • 15
    • 0035865338 scopus 로고    scopus 로고
    • Autologous regulation of naive T cell homeostasis within the T cell compartment
    • Dummer W., Ernst B., LeRoy E., Lee D., Surh C. Autologous regulation of naive T cell homeostasis within the T cell compartment. J. Immunol. 166:2001;2460-2468.
    • (2001) J. Immunol. , vol.166 , pp. 2460-2468
    • Dummer, W.1    Ernst, B.2    LeRoy, E.3    Lee, D.4    Surh, C.5
  • 16
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst B., Lee D.S., Chang J.M., Sprent J., Surh C.D. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity. 11:1999;173-181.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 17
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • Fehniger T.A., Caligiuri M.A. Interleukin 15: biology and relevance to human disease. Blood. 97:2001;14-32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 19
    • 0035905477 scopus 로고    scopus 로고
    • Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells
    • Geginat J., Sallusto F., Lanzavecchia A. Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells. J. Exp. Med. 194:2001;1711-1719.
    • (2001) J. Exp. Med. , vol.194 , pp. 1711-1719
    • Geginat, J.1    Sallusto, F.2    Lanzavecchia, A.3
  • 22
    • 0033581935 scopus 로고    scopus 로고
    • Selecting and maintaining a diverse T-cell repertoire
    • Goldrath A.W., Bevan M.J. Selecting and maintaining a diverse T-cell repertoire. Nature. 402:1999;255-262.
    • (1999) Nature , vol.402 , pp. 255-262
    • Goldrath, A.W.1    Bevan, M.J.2
  • 23
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath A.W., Bogatzki L.Y., Bevan M.J. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 192:2000;557-564.
    • (2000) J. Exp. Med. , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 26
    • 0033539516 scopus 로고    scopus 로고
    • Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands
    • Kieper W.C., Jameson S.C. Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands. Proc. Natl. Acad. Sci. U.S.A. 96:1999;13306-13311.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 13306-13311
    • Kieper, W.C.1    Jameson, S.C.2
  • 30
    • 0029788297 scopus 로고    scopus 로고
    • Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells
    • Leclercq G., Debacker V., de Smedt M., Plum J. Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells. J. Exp. Med. 184:1996;325-336.
    • (1996) J. Exp. Med. , vol.184 , pp. 325-336
    • Leclercq, G.1    Debacker, V.2    De Smedt, M.3    Plum, J.4
  • 31
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce J.P., Boone D.L., Chai S., Swain R.E., Dassopoulos T., Treffin S., Ma A. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity. 9:1998;669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3    Swain, R.E.4    Dassopoulos, T.5    Treffin, S.6    Ma, A.7
  • 32
    • 0035886940 scopus 로고    scopus 로고
    • T cell-independent interleukin 15r alpha signals are required for bystander proliferation
    • Lodolce J.P., Burkett P.R., Boone D.L., Chien M., Ma A. T cell-independent interleukin 15r alpha signals are required for bystander proliferation. J. Exp. Med. 194:2001;1187-1194.
    • (2001) J. Exp. Med. , vol.194 , pp. 1187-1194
    • Lodolce, J.P.1    Burkett, P.R.2    Boone, D.L.3    Chien, M.4    Ma, A.5
  • 33
    • 0034610983 scopus 로고    scopus 로고
    • The pleiotropic functions of interleukin 15: Not so interleukin 2-like after all
    • Ma A., Boone D.L., Lodolce J.P. The pleiotropic functions of interleukin 15: not so interleukin 2-like after all. J. Exp. Med. 191:2000;753-756.
    • (2000) J. Exp. Med. , vol.191 , pp. 753-756
    • Ma, A.1    Boone, D.L.2    Lodolce, J.P.3
  • 34
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust D., Vezys V., Marzo A.L., Lefrancois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science. 291:2001;2413-2417.
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 35
    • 0035423390 scopus 로고    scopus 로고
    • IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation
    • Mattei F., Schiavoni G., Belardelli F., Tough D.F. IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation. J. Immunol. 167:2001;1179-1187.
    • (2001) J. Immunol. , vol.167 , pp. 1179-1187
    • Mattei, F.1    Schiavoni, G.2    Belardelli, F.3    Tough, D.F.4
  • 36
    • 0034663776 scopus 로고    scopus 로고
    • Cutting edge: Naive T cells masquerading as memory cells
    • Murali-Krishna K., Ahmed R. Cutting edge: naive T cells masquerading as memory cells. J. Immunol. 165:2000;1733-1737.
    • (2000) J. Immunol. , vol.165 , pp. 1733-1737
    • Murali-Krishna, K.1    Ahmed, R.2
  • 38
    • 0035500282 scopus 로고    scopus 로고
    • Lipopolysaccharide-stimulated or granulocyte-macrophage colony-stimulating factor-stimulated monocytes rapidly express biologically active IL-15 on their cell surface independent of new protein synthesis
    • Neely G.G., Robbins S.M., Amankwah E.K., Epelman S., Wong H., Spurrell J.C., Jandu K.K., Zhu W., Fogg D.K., Brown C.B., Mody C.H. Lipopolysaccharide-stimulated or granulocyte-macrophage colony-stimulating factor-stimulated monocytes rapidly express biologically active IL-15 on their cell surface independent of new protein synthesis. J. Immunol. 167:2001;5011-5017.
    • (2001) J. Immunol. , vol.167 , pp. 5011-5017
    • Neely, G.G.1    Robbins, S.M.2    Amankwah, E.K.3    Epelman, S.4    Wong, H.5    Spurrell, J.C.6    Jandu, K.K.7    Zhu, W.8    Fogg, D.K.9    Brown, C.B.10    Mody, C.H.11
  • 40
    • 0032586823 scopus 로고    scopus 로고
    • Naive cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?
    • Oehen S., Brduscha-Riem K. Naive cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: a pitfall for T cell memory studies? Eur. J. Immunol. 29:1999;608-614.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 608-614
    • Oehen, S.1    Brduscha-Riem, K.2
  • 41
    • 0035202257 scopus 로고    scopus 로고
    • Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response
    • Ohteki T., Suzue K., Maki C., Ota T., Koyasu S. Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response. Nat. Immunol. 2:2001;1138-1143.
    • (2001) Nat. Immunol. , vol.2 , pp. 1138-1143
    • Ohteki, T.1    Suzue, K.2    Maki, C.3    Ota, T.4    Koyasu, S.5
  • 42
    • 0030639208 scopus 로고    scopus 로고
    • Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms
    • Onu A., Pohl T., Krause H., Bulfone-Paus S. Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms. J. Immunol. 158:1997;255-262.
    • (1997) J. Immunol. , vol.158 , pp. 255-262
    • Onu, A.1    Pohl, T.2    Krause, H.3    Bulfone-Paus, S.4
  • 44
    • 0033248123 scopus 로고    scopus 로고
    • IL-2Rbeta/IL-7Ralpha doubly deficient mice recapitulate the thymic and intraepithelial lymphocyte (IEL) developmental defects of gammac-/- mice: Roles for both IL-2 and IL-15 in CD8alphaalpha IEL development
    • Porter B.O., Malek T.R. IL-2Rbeta/IL-7Ralpha doubly deficient mice recapitulate the thymic and intraepithelial lymphocyte (IEL) developmental defects of gammac-/- mice: roles for both IL-2 and IL-15 in CD8alphaalpha IEL development. J. Immunol. 163:1999;5906-5912.
    • (1999) J. Immunol. , vol.163 , pp. 5906-5912
    • Porter, B.O.1    Malek, T.R.2
  • 45
    • 0035889933 scopus 로고    scopus 로고
    • Homeostatic expansion occurs independently of costimulatory signals
    • Prlic M., Blazar B.R., Khoruts A., Zell T., Jameson S.C. Homeostatic expansion occurs independently of costimulatory signals. J. Immunol. 167:2001;5664-5668.
    • (2001) J. Immunol. , vol.167 , pp. 5664-5668
    • Prlic, M.1    Blazar, B.R.2    Khoruts, A.3    Zell, T.4    Jameson, S.C.5
  • 46
    • 0030588575 scopus 로고    scopus 로고
    • IL-15 can substitute for the marrow microenvironment in the differentiation of natural killer cells
    • Puzanov I.J., Bennett M., Kumar V. IL-15 can substitute for the marrow microenvironment in the differentiation of natural killer cells. J. Immunol. 157:1996;4282-4285.
    • (1996) J. Immunol. , vol.157 , pp. 4282-4285
    • Puzanov, I.J.1    Bennett, M.2    Kumar, V.3
  • 47
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt R.L., Khoruts A., Merica R., Zell T., Jenkins M.K. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 410:2001;101-105.
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 48
    • 0024332461 scopus 로고
    • Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo
    • Rocha B., Dautigny N., Pereira P. Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo. Eur. J. Immunol. 19:1989;905-911.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 905-911
    • Rocha, B.1    Dautigny, N.2    Pereira, P.3
  • 49
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B., Merz H., Schorle H., Schimpl A., Feller A.C., Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell. 75:1993;253-261.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horak, I.6
  • 51
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F., Lenig D., Forster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 401:1999;708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 52
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns K.S., Kieper W.C., Jameson S.C., Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1:2000;426-432.
    • (2000) Nat. Immunol. , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 53
    • 0032433054 scopus 로고    scopus 로고
    • Type I interferon-mediated stimulation of T cells by CpG DNA
    • Sun S., Zhang X., Tough D.F., Sprent J. Type I interferon-mediated stimulation of T cells by CpG DNA. J. Exp. Med. 188:1998;2335-2342.
    • (1998) J. Exp. Med. , vol.188 , pp. 2335-2342
    • Sun, S.1    Zhang, X.2    Tough, D.F.3    Sprent, J.4
  • 54
    • 0034698825 scopus 로고    scopus 로고
    • Homeostatic T cell proliferation: How far can T cells be activated to self-ligands?
    • Surh C.D., Sprent J. Homeostatic T cell proliferation: how far can T cells be activated to self-ligands? J. Exp. Med. 192:2000;F9-F14.
    • (2000) J. Exp. Med. , vol.192
    • Surh, C.D.1    Sprent, J.2
  • 55
    • 0031051547 scopus 로고    scopus 로고
    • Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain
    • Suzuki H., Duncan G.S., Takimoto H., Mak T.W. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain. J. Exp. Med. 185:1997;499-505.
    • (1997) J. Exp. Med. , vol.185 , pp. 499-505
    • Suzuki, H.1    Duncan, G.S.2    Takimoto, H.3    Mak, T.W.4
  • 57
    • 0029946063 scopus 로고    scopus 로고
    • IL-15: A pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels
    • Tagaya Y., Bamford R.N., DeFilippis A.P., Waldmann T.A. IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity. 4:1996a;329-336.
    • (1996) Immunity , vol.4 , pp. 329-336
    • Tagaya, Y.1    Bamford, R.N.2    DeFilippis, A.P.3    Waldmann, T.A.4
  • 58
    • 0029811474 scopus 로고    scopus 로고
    • Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells
    • Tagaya Y., Burton J.D., Miyamoto Y., Waldmann T.A. Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells. EMBO J. 15:1996b;4928-4939.
    • (1996) EMBO J. , vol.15 , pp. 4928-4939
    • Tagaya, Y.1    Burton, J.D.2    Miyamoto, Y.3    Waldmann, T.A.4
  • 61
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough D.F., Borrow P., Sprent J. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science. 272:1996;1947-1950.
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.F.1    Borrow, P.2    Sprent, J.3
  • 62
    • 0030918819 scopus 로고    scopus 로고
    • T cell stimulation in vivo by lipopolysaccharide (LPS)
    • Tough D.F., Sun S., Sprent J. T cell stimulation in vivo by lipopolysaccharide (LPS). J. Exp. Med. 185:1997;2089-2094.
    • (1997) J. Exp. Med. , vol.185 , pp. 2089-2094
    • Tough, D.F.1    Sun, S.2    Sprent, J.3
  • 63
    • 0037079709 scopus 로고    scopus 로고
    • Enforced expression of the Ikaros isoform IKS decreases the numbers of extrathymic intraepithelial lymphocytes and natural killer 1.1+ T cells
    • Tucker S.N., Jessup H.K., Fujii H., Wilson C.B. Enforced expression of the Ikaros isoform IKS decreases the numbers of extrathymic intraepithelial lymphocytes and natural killer 1.1+ T cells. Blood. 99:2002;513-519.
    • (2002) Blood , vol.99 , pp. 513-519
    • Tucker, S.N.1    Jessup, H.K.2    Fujii, H.3    Wilson, C.B.4
  • 65
    • 0035814926 scopus 로고    scopus 로고
    • Cytokines: IL-21 joins the gamma(c)-dependent network?
    • Vosshenrich C.A., Di Santo J.P. Cytokines: IL-21 joins the gamma(c)-dependent network? Curr. Biol. 11:2001;R175-R177.
    • (2001) Curr. Biol. , vol.11
    • Vosshenrich, C.A.1    Di Santo, J.P.2
  • 66
    • 0028784289 scopus 로고
    • Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford D.M., Chen J., Ferry J.A., Davidson L., Ma A., Alt F.W. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity. 3:1995;521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 67
    • 0034965185 scopus 로고    scopus 로고
    • Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: Evidence for two distinct regulatory mechanisms
    • Wolf M., Schimpl A., Hunig T. Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms. Eur. J. Immunol. 31:2001;1637-1645.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1637-1645
    • Wolf, M.1    Schimpl, A.2    Hunig, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.