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Volumn 101, Issue 3, 1998, Pages 410-420

Effect of fexofenadine on eosinophil-induced changes in epithelial permeability and cytokine release from nasal epithelial cells of patients with seasonal allergic rhinitis

Author keywords

Allergic rhinitis; Cytokines; Eosinophils; Epithelial permeability; Fexofenadine; Nasal epithelial cells

Indexed keywords

FEXOFENADINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; RANTES; TERFENADINE;

EID: 0031920720     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70256-8     Document Type: Article
Times cited : (129)

References (61)
  • 2
    • 0026477886 scopus 로고
    • Eosinophils and neutrophils
    • Kay AB, Corrigan CJ. Eosinophils and neutrophils. Br Med Bull 1991;48:51-64.
    • (1991) Br Med Bull , vol.48 , pp. 51-64
    • Kay, A.B.1    Corrigan, C.J.2
  • 3
    • 0025877106 scopus 로고
    • The role of inflammatory cells in the pathogenesis of asthma and chronic obstructive pulmonary disease
    • Corrigan CJ, Kay AB. The role of inflammatory cells in the pathogenesis of asthma and chronic obstructive pulmonary disease. Am Rev Respir Dis 1991;143:1165-8.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1165-1168
    • Corrigan, C.J.1    Kay, A.B.2
  • 4
    • 0024447208 scopus 로고
    • Are blood eosinophil number and activity important for the development of the late asthmatic reaction after allergen challenge?
    • Venge P, Dahl R. Are blood eosinophil number and activity important for the development of the late asthmatic reaction after allergen challenge? Eur Respir J 1989;2:430S-4S.
    • (1989) Eur Respir J , vol.2
    • Venge, P.1    Dahl, R.2
  • 5
    • 0026915515 scopus 로고
    • The effect of activated eosinophils on cultured human nasal epithelial cell activity and the influence of nedocromil sodium in vitro
    • Devalia JL, Sapsford R, Rusznak C, Davies R. The effect of activated eosinophils on cultured human nasal epithelial cell activity and the influence of nedocromil sodium in vitro. Am J Respir Cell Mol Biol 1992;7:270-7.
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 270-277
    • Devalia, J.L.1    Sapsford, R.2    Rusznak, C.3    Davies, R.4
  • 6
    • 0024309120 scopus 로고
    • Cytological changes in the nasal secretion during late nasal response
    • Pelikan Z, Pelikan-Filipek M. Cytological changes in the nasal secretion during late nasal response. J Allergy Clin Immunol 1989;63:1068-79.
    • (1989) J Allergy Clin Immunol , vol.63 , pp. 1068-1079
    • Pelikan, Z.1    Pelikan-Filipek, M.2
  • 7
    • 0024202874 scopus 로고
    • The cellular response of the human nasal mucosa to natural allergen response
    • Pipkorn U, Karlsson G, Enerback L. The cellular response of the human nasal mucosa to natural allergen response. J Allergy Clin Immunol 1988;63:1046-54.
    • (1988) J Allergy Clin Immunol , vol.63 , pp. 1046-1054
    • Pipkorn, U.1    Karlsson, G.2    Enerback, L.3
  • 8
    • 0018568643 scopus 로고
    • Symptoms of chronic and allergic rhinitis and occurrence of nasal secretion granulocytes in university students, school children and infants
    • Malmberg H. Symptoms of chronic and allergic rhinitis and occurrence of nasal secretion granulocytes in university students, school children and infants. Allergy 1979;34:389-4.
    • (1979) Allergy , vol.34 , pp. 389-394
    • Malmberg, H.1
  • 10
    • 0026464603 scopus 로고
    • Expression and generation of interleukin-8, IL-6, granulocyte-macrophage-colony stimulating factor by bronchial epithelial cells and enhancement by interleukin-1β and tumour necrosis factor-a
    • Cromwell O, Hamid Q, Corrigan CJ, Barkans J, Meng Q, Collins PD, et al. Expression and generation of interleukin-8, IL-6, granulocyte-macrophage-colony stimulating factor by bronchial epithelial cells and enhancement by interleukin-1β and tumour necrosis factor-a. Immunology 1992;77:330-7.
    • (1992) Immunology , vol.77 , pp. 330-337
    • Cromwell, O.1    Hamid, Q.2    Corrigan, C.J.3    Barkans, J.4    Meng, Q.5    Collins, P.D.6
  • 11
    • 0027669560 scopus 로고
    • The effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro
    • Devalia JL, Campbell AM, Sapsford R, Rusnak C, Quint D, Godard P, et al. The effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro. Am J Respir Cell Mol Biol 1993;9:271-8.
    • (1993) Am J Respir Cell Mol Biol , vol.9 , pp. 271-278
    • Devalia, J.L.1    Campbell, A.M.2    Sapsford, R.3    Rusnak, C.4    Quint, D.5    Godard, P.6
  • 12
    • 33646956883 scopus 로고    scopus 로고
    • Expression of RANTES in human bronchial epithelial cells in vitro and in vivo and the effect of corticosteroids
    • Wang JH, Devalia JL, Xia C, Sapsford R, Davies R. Expression of RANTES in human bronchial epithelial cells in vitro and in vivo and the effect of corticosteroids. Am J Respir Cell Mol Biol 1996;9:271-8.
    • (1996) Am J Respir Cell Mol Biol , vol.9 , pp. 271-278
    • Wang, J.H.1    Devalia, J.L.2    Xia, C.3    Sapsford, R.4    Davies, R.5
  • 13
    • 0011822725 scopus 로고
    • Human bronchial epithelial cells exposed to isocyanates potentiate the activation and proliferation of T cells induced by antigen receptor triggering through the release of IL-1 and IL-6
    • Johanssen SGO, editor. Award Book 1990. Upssala: AW Graflska
    • Mattoli S, Miante S, Calabro F, Mazzetti M, Allegra L. Human bronchial epithelial cells exposed to isocyanates potentiate the activation and proliferation of T cells induced by antigen receptor triggering through the release of IL-1 and IL-6. In: Johanssen SGO, editor. Pharmacia Allergy Research Foundation. Award Book 1990. Upssala: AW Graflska; 1990. p. 25-35.
    • (1990) Pharmacia Allergy Research Foundation. , pp. 25-35
    • Mattoli, S.1    Miante, S.2    Calabro, F.3    Mazzetti, M.4    Allegra, L.5
  • 14
    • 0029315090 scopus 로고
    • Bronchial epithelial cell-cytokine interactions in airway inflammation
    • Levine SJ. Bronchial epithelial cell-cytokine interactions in airway inflammation. J Invest Med 1995;43:241-9.
    • (1995) J Invest Med , vol.43 , pp. 241-249
    • Levine, S.J.1
  • 15
    • 0029556783 scopus 로고
    • The effect of conditioned medium from cultured human bronchial epithelial cells on eosinophil and neutrophil chemotaxis and adherence, in vitro
    • Abdelaziz MM, Devalia JL, Khair OA, Calderon M, Sapsford R, Davies R. The effect of conditioned medium from cultured human bronchial epithelial cells on eosinophil and neutrophil chemotaxis and adherence, in vitro. Am J Respir Cell Mol Biol 1995;13:728-37.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 728-737
    • Abdelaziz, M.M.1    Devalia, J.L.2    Khair, O.A.3    Calderon, M.4    Sapsford, R.5    Davies, R.6
  • 16
    • 0027494730 scopus 로고
    • Anti-inflammatory actions of steroids: Molecular mechanisms
    • Barnes PJ, Adock I. Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol Sci 1993;14:436-41.
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 436-441
    • Barnes, P.J.1    Adock, I.2
  • 17
    • 0027176276 scopus 로고
    • Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids
    • Sousa AR, Poston RN, Lane SJ, Nakhosteen JA, Lee TH. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am Rev Respir Dis 1993;147:1557-61.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1557-1561
    • Sousa, A.R.1    Poston, R.N.2    Lane, S.J.3    Nakhosteen, J.A.4    Lee, T.H.5
  • 20
    • 0024307222 scopus 로고
    • Mediators and nasal allergy
    • Pipkorn U. Mediators and nasal allergy. Clin Exp Allergy 1989;26:585-9.
    • (1989) Clin Exp Allergy , vol.26 , pp. 585-589
    • Pipkorn, U.1
  • 23
    • 0024435806 scopus 로고
    • Inhibitory effect of terfenadine on mediator release from human blood basophils and eosinophils
    • Nabe M, Agrawal DK, Sarmiento EU, Townley RG. Inhibitory effect of terfenadine on mediator release from human blood basophils and eosinophils. Clin Exp Allergy 1989;19:515-20.
    • (1989) Clin Exp Allergy , vol.19 , pp. 515-520
    • Nabe, M.1    Agrawal, D.K.2    Sarmiento, E.U.3    Townley, R.G.4
  • 24
    • 0023484111 scopus 로고
    • Antiallergic effects of terfenaine on immediate type hypersensitivity reactions
    • Akagi M, Mio M, Miyoshi K, Tasaka K. Antiallergic effects of terfenaine on immediate type hypersensitivity reactions. Immunopharmacol Immunotoxicol 1987;9:257-79.
    • (1987) Immunopharmacol Immunotoxicol , vol.9 , pp. 257-279
    • Akagi, M.1    Mio, M.2    Miyoshi, K.3    Tasaka, K.4
  • 25
    • 0024506787 scopus 로고
    • Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine
    • De Vos C, Joseph M, Leprevost C, Vorng H, Tomassini M, Capron M, et al. Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine. Int Arch Allergy Appl Immunol 1989;88:212-5.
    • (1989) Int Arch Allergy Appl Immunol , vol.88 , pp. 212-215
    • De Vos, C.1    Joseph, M.2    Leprevost, C.3    Vorng, H.4    Tomassini, M.5    Capron, M.6
  • 26
    • 0026700961 scopus 로고
    • The effects of cetirizine on the adhesion of human eosinophils and neutrophils to cultured human umbilical vein endothelial cells
    • Kyan-Aung U, Hallsworth M, Haskard D, De Vos C, Lee T. The effects of cetirizine on the adhesion of human eosinophils and neutrophils to cultured human umbilical vein endothelial cells. J Allergy Clin Immunol 1992;90:270-2.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 270-272
    • Kyan-Aung, U.1    Hallsworth, M.2    Haskard, D.3    De Vos, C.4    Lee, T.5
  • 27
    • 0000096993 scopus 로고
    • Mass balance and pharmacokinetics of fexofenadine HCI in healthy, male volunteers
    • Lippert C, Ling J, Brown P, Burmaster S, Eller M, Cheng L, et al. Mass balance and pharmacokinetics of fexofenadine HCI in healthy, male volunteers. Pharm Res 1995;12(suppl 1):S390.
    • (1995) Pharm Res , vol.12 , Issue.1 SUPPL.
    • Lippert, C.1    Ling, J.2    Brown, P.3    Burmaster, S.4    Eller, M.5    Cheng, L.6
  • 28
    • 0031017632 scopus 로고    scopus 로고
    • A comparison of cytokine release from epithelial cells cultured from nasal biopsy specimens of atopic patients with and without rhinitis, and nonatopic subjects without rhinitis
    • Calderön MA, Devalia JL, Prior AJ, Sapsford R, Davies R. A comparison of cytokine release from epithelial cells cultured from nasal biopsy specimens of atopic patients with and without rhinitis, and nonatopic subjects without rhinitis. J Allergy Clin Immunol 1997;99:65-76.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 65-76
    • Calderön, M.A.1    Devalia, J.L.2    Prior, A.J.3    Sapsford, R.4    Davies, R.5
  • 29
    • 0025171382 scopus 로고
    • Culture and comparison of human bronchial and nasal epithelial cells in vitro
    • Devalia JL, Sapsford R, Wells C, Richman P, Davies R. Culture and comparison of human bronchial and nasal epithelial cells in vitro. Respir Med 1990;84:303-12.
    • (1990) Respir Med , vol.84 , pp. 303-312
    • Devalia, J.L.1    Sapsford, R.2    Wells, C.3    Richman, P.4    Davies, R.5
  • 30
    • 0028052178 scopus 로고
    • No effect of histamine on human bronchial epithelial cell permeability and tight junctional integrity in vitro
    • Devalia JL, Godfrey RWA, Sapsford R, Severs NJ, Jeffery PK, Davies R. No effect of histamine on human bronchial epithelial cell permeability and tight junctional integrity in vitro. Eur Respir J 1994;7:1958-65.
    • (1994) Eur Respir J , vol.7 , pp. 1958-1965
    • Devalia, J.L.1    Godfrey, R.W.A.2    Sapsford, R.3    Severs, N.J.4    Jeffery, P.K.5    Davies, R.6
  • 31
    • 0024539177 scopus 로고
    • Hypodense eosinophilic granulocytes in normal individuals and patients with asthma: Generation of hypodense cell populations in vitro
    • Kloprogge E, de Leeuw AJ, de Monchy JGR, Kauffman HF. Hypodense eosinophilic granulocytes in normal individuals and patients with asthma: generation of hypodense cell populations in vitro. J Allergy Clin Immunol 1989;83:393-400.
    • (1989) J Allergy Clin Immunol , vol.83 , pp. 393-400
    • Kloprogge, E.1    De Leeuw, A.J.2    De Monchy, J.G.R.3    Kauffman, H.F.4
  • 32
    • 0015883441 scopus 로고
    • Basophils in bronchial asthma with reference to reagin-type allergy
    • Kimura I, Moritani Y, Tanizaki Y. Basophils in bronchial asthma with reference to reagin-type allergy. Clin Allergy 1973;3:195-202.
    • (1973) Clin Allergy , vol.3 , pp. 195-202
    • Kimura, I.1    Moritani, Y.2    Tanizaki, Y.3
  • 33
    • 4844222228 scopus 로고
    • Modified Boyden chamber method of measuring polymorphonuclear leukocyte chemotaxis
    • Gallin JI, Quie PG, editors. New York: Raven Press
    • Cates KL, Ray CE, Quie PG. Modified Boyden chamber method of measuring polymorphonuclear leukocyte chemotaxis. In: Gallin JI, Quie PG, editors. Leukocyte chemotaxis: methods, physiology, and clinical implications. New York: Raven Press; 1978. p. 67-71.
    • (1978) Leukocyte Chemotaxis: Methods, Physiology, and Clinical Implications. , pp. 67-71
    • Cates, K.L.1    Ray, C.E.2    Quie, P.G.3
  • 34
    • 0019876870 scopus 로고
    • The reactive cleavage of the myeloperoxidase in half, producing enzymatically active hemi-myeloperoxidase
    • Andrews PC, Krinsky NI. The reactive cleavage of the myeloperoxidase in half, producing enzymatically active hemi-myeloperoxidase. J Biol Chem 1981;256:4211-8.
    • (1981) J Biol Chem , vol.256 , pp. 4211-4218
    • Andrews, P.C.1    Krinsky, N.I.2
  • 35
    • 0029130433 scopus 로고
    • Pharmacological modulation of IL-6 and IL-8 secretion by H-antagonist decarboethoxy-loratadine and dexamethasone by human mast and basophilic cell lines
    • Lippert U, Kruger-Krasagakes S, Moller A, Kiessling U, Czarnetzki BM. Pharmacological modulation of IL-6 and IL-8 secretion by H-antagonist decarboethoxy-loratadine and dexamethasone by human mast and basophilic cell lines. Exp Dermatol 1995;4:272-6.
    • (1995) Exp Dermatol , vol.4 , pp. 272-276
    • Lippert, U.1    Kruger-Krasagakes, S.2    Moller, A.3    Kiessling, U.4    Czarnetzki, B.M.5
  • 36
    • 0029010698 scopus 로고
    • Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells
    • Vignola AM, Crampette L, Mondain M, Sauvere G, Czarlewski W, Bousquet J, et al. Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells. Allergy 1995;50:200-3.
    • (1995) Allergy , vol.50 , pp. 200-203
    • Vignola, A.M.1    Crampette, L.2    Mondain, M.3    Sauvere, G.4    Czarlewski, W.5    Bousquet, J.6
  • 37
    • 0029070965 scopus 로고
    • Loratadine reduces allergen-induced mucosal output of a2-macr°globulin and tryptase in allergic rhinitis
    • Greiff L, Persson CGA, Svensson C, Enander I, Anderson M. Loratadine reduces allergen-induced mucosal output of a2-macr°globulin and tryptase in allergic rhinitis. J Allergy Clin Immunol 1995;96:97-103.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 97-103
    • Greiff, L.1    Persson, C.G.A.2    Svensson, C.3    Enander, I.4    Anderson, M.5
  • 38
    • 0030444684 scopus 로고    scopus 로고
    • Topical azelastine reduces eosinophil and intercellular adhesion molecule-1 expression on nasal epithelial cells: An antiallergic activity
    • Ciprandi G, Pronzato C, Passalacqua G, Ricca V, Bagnasco M, Grogen J, et al. Topical azelastine reduces eosinophil and intercellular adhesion molecule-1 expression on nasal epithelial cells: an antiallergic activity. J Allergy Clin Immunol 1996;96:1088-96.
    • (1996) J Allergy Clin Immunol , vol.96 , pp. 1088-1096
    • Ciprandi, G.1    Pronzato, C.2    Passalacqua, G.3    Ricca, V.4    Bagnasco, M.5    Grogen, J.6
  • 39
    • 0029116991 scopus 로고
    • Terfenadine exerts antiallergic activity reducing ICAM-1 expression on nasal epithelial cells in patients with pollen allergy
    • Ciprandi G, Pronzato C, Ricca V, Varese P, Del Giacco OS, Canonica GW. Terfenadine exerts antiallergic activity reducing ICAM-1 expression on nasal epithelial cells in patients with pollen allergy. Clin Exp Allergy 1995;25:871-8.
    • (1995) Clin Exp Allergy , vol.25 , pp. 871-878
    • Ciprandi, G.1    Pronzato, C.2    Ricca, V.3    Varese, P.4    Del Giacco, O.S.5    Canonica, G.W.6
  • 40
    • 0029662151 scopus 로고    scopus 로고
    • Effect of HI and H2 antagonists on nasal symptoms and mediator release in atopic patients after nasal allergen challenge during the pollen season
    • Wang D, Clement P, Smitz J. Effect of HI and H2 antagonists on nasal symptoms and mediator release in atopic patients after nasal allergen challenge during the pollen season. Acta Otolaryngol 1996;116:91-6.
    • (1996) Acta Otolaryngol , vol.116 , pp. 91-96
    • Wang, D.1    Clement, P.2    Smitz, J.3
  • 41
    • 0030950378 scopus 로고    scopus 로고
    • The effect of fluticasone propionate aqueous nasal spray on eosinophils and cytokines in nasal secretions of patients with ragweed allergic rhinitis
    • Alvarado-Valdes CA, Blomgren J, Weiler D, Gleich GJ, Reed CE, Field EA, et al. The effect of fluticasone propionate aqueous nasal spray on eosinophils and cytokines in nasal secretions of patients with ragweed allergic rhinitis. Clin Ther 1997;19:273-81.
    • (1997) Clin Ther , vol.19 , pp. 273-281
    • Alvarado-Valdes, C.A.1    Blomgren, J.2    Weiler, D.3    Gleich, G.J.4    Reed, C.E.5    Field, E.A.6
  • 42
    • 85004775232 scopus 로고
    • Inhibitory effect of ceterizine 2HC1 on eosinophil migration in vivo
    • Fadel R, Herpin-Richard N, Rihoux JP, Henocq E. Inhibitory effect of ceterizine 2HC1 on eosinophil migration in vivo. Clin Allergy 1987;17:373-9.
    • (1987) Clin Allergy , vol.17 , pp. 373-379
    • Fadel, R.1    Herpin-Richard, N.2    Rihoux, J.P.3    Henocq, E.4
  • 43
    • 0023784858 scopus 로고
    • Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin
    • Michel L, De Vos C, Rihoux JP, Burtin C, Benveniste J, Dubertret L. Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin. J Allergy Clin Immunol 1988;82:101-9.
    • (1988) J Allergy Clin Immunol , vol.82 , pp. 101-109
    • Michel, L.1    De Vos, C.2    Rihoux, J.P.3    Burtin, C.4    Benveniste, J.5    Dubertret, L.6
  • 44
    • 0024333843 scopus 로고
    • Effect of ceterizine on mast cell-mediator release and cellular traffic during the cutaneous late-phase reaction
    • Charlesworth EN, Kagey-Sobotka A, Norman PS, Lichtenstein LM. Effect of ceterizine on mast cell-mediator release and cellular traffic during the cutaneous late-phase reaction. J Allergy Clin Immunol 1989;83:905-12.
    • (1989) J Allergy Clin Immunol , vol.83 , pp. 905-912
    • Charlesworth, E.N.1    Kagey-Sobotka, A.2    Norman, P.S.3    Lichtenstein, L.M.4
  • 45
    • 0025216725 scopus 로고
    • Terfenadine: An updated review of its pharmacological properties and therapeutic efficacy
    • Mctavish D, Goa KL, Ferrill M. Terfenadine: an updated review of its pharmacological properties and therapeutic efficacy. Drugs 1990;39:552-74.
    • (1990) Drugs , vol.39 , pp. 552-574
    • Mctavish, D.1    Goa, K.L.2    Ferrill, M.3
  • 46
    • 0023163754 scopus 로고
    • Terfenadine is a potent and selective histamine H; receptor antagonist in asthmatic airways
    • Rafferty P, Holgate ST. Terfenadine is a potent and selective histamine H; receptor antagonist in asthmatic airways. Am Rev Respir Dis 1987;135:181-4.
    • (1987) Am Rev Respir Dis , vol.135 , pp. 181-184
    • Rafferty, P.1    Holgate, S.T.2
  • 47
    • 0023554639 scopus 로고
    • The contribution of histamine to immediate bronchoconstriction provoked by allergen and adenosine 5'-monophosphate in atopic asthma
    • Rafferty P, Beasley R, Holgate ST. The contribution of histamine to immediate bronchoconstriction provoked by allergen and adenosine 5'-monophosphate in atopic asthma. Am Rev Respir Dis 1987;136:369-73.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 369-373
    • Rafferty, P.1    Beasley, R.2    Holgate, S.T.3
  • 48
    • 0021271414 scopus 로고
    • Terfenadine in exercise induced asthma
    • Patel KR. Terfenadine in exercise induced asthma. BMJ 1984;288:1496-7.
    • (1984) BMJ , vol.288 , pp. 1496-1497
    • Patel, K.R.1
  • 49
    • 0029883856 scopus 로고    scopus 로고
    • Dose-response relation between terfenadine (Seldane) and the QTc interval on the scalar electrocardiogram: Distinguishing a drug effect from spontaneous variability
    • Pratt CM, Ruberg S, Morganroth J, McNutt B, Woodward J, Harris S, et al. Dose-response relation between terfenadine (Seldane) and the QTc interval on the scalar electrocardiogram: distinguishing a drug effect from spontaneous variability. Am Heart J 1996;131:472-80.
    • (1996) Am Heart J , vol.131 , pp. 472-480
    • Pratt, C.M.1    Ruberg, S.2    Morganroth, J.3    McNutt, B.4    Woodward, J.5    Harris, S.6
  • 50
    • 0001809585 scopus 로고    scopus 로고
    • Effect of fexofenadine HC1 on corrected QT interval (QTc)
    • Pratt C, Mason J, Russell T, Ahlbrandt R. Effect of fexofenadine HC1 on corrected QT interval (QTc). Allergy 1997;52(suppl 37):67.
    • (1997) Allergy , vol.52 , Issue.37 SUPPL. , pp. 67
    • Pratt, C.1    Mason, J.2    Russell, T.3    Ahlbrandt, R.4
  • 52
    • 0029164318 scopus 로고
    • Molecular pharmacological aspects of histamine receptors
    • Leurs R, Smit MJ, Timmerman H. Molecular pharmacological aspects of histamine receptors. Pharmacol Ther 1995;66:413-63.
    • (1995) Pharmacol Ther , vol.66 , pp. 413-463
    • Leurs, R.1    Smit, M.J.2    Timmerman, H.3
  • 53
    • 0027065041 scopus 로고
    • Histamine increases cytosolic Ca2+ in HL-60 promyelocytes predominantly via H2 receptors with an unique agonist/antagonist profile and induces functional differentiation
    • Seifert R, Hoer A, Schwaner I, Buschauer A. Histamine increases cytosolic Ca2+ in HL-60 promyelocytes predominantly via H2 receptors with an unique agonist/antagonist profile and induces functional differentiation. Mol Pharmacol 1992;42:235-41.
    • (1992) Mol Pharmacol , vol.42 , pp. 235-241
    • Seifert, R.1    Hoer, A.2    Schwaner, I.3    Buschauer, A.4
  • 54
    • 0026729484 scopus 로고
    • Mechanism of inhibitory effects of azelastine on smooth muscle contraction
    • Masuo M, Shimada T, Kitazawa T. Mechanism of inhibitory effects of azelastine on smooth muscle contraction. J Pharmacol Exp Ther 1992;26:1300-8.
    • (1992) J Pharmacol Exp Ther , vol.26 , pp. 1300-1308
    • Masuo, M.1    Shimada, T.2    Kitazawa, T.3
  • 55
    • 0028341226 scopus 로고
    • Effects of azelastine on membrane currents in tracheal smooth muscle cells isolated from the guinea pig
    • Hazama H, Nakajima T, Hisada T, Hamada E, Omata M, Kurachi Y. Effects of azelastine on membrane currents in tracheal smooth muscle cells isolated from the guinea pig. Eur J Pharmacol 1994;259:143-50.
    • (1994) Eur J Pharmacol , vol.259 , pp. 143-150
    • Hazama, H.1    Nakajima, T.2    Hisada, T.3    Hamada, E.4    Omata, M.5    Kurachi, Y.6
  • 56
    • 0028167658 scopus 로고
    • Inhibitory effect of the H; antagonist loratadine on histamine release from human basophils
    • Miadonna A, Milazzo N, Lorini M, Marchesi E, Tedeschi A. Inhibitory effect of the H; antagonist loratadine on histamine release from human basophils. Int Arch Allergy Immunol 1994;105:12-7.
    • (1994) Int Arch Allergy Immunol , vol.105 , pp. 12-17
    • Miadonna, A.1    Milazzo, N.2    Lorini, M.3    Marchesi, E.4    Tedeschi, A.5
  • 57
    • 0025864589 scopus 로고
    • Locating intracellular calcium stores
    • Burgoyne RD, Cheek TR. Locating intracellular calcium stores. Trends Biochem Sci 1991;16:319-20.
    • (1991) Trends Biochem Sci , vol.16 , pp. 319-320
    • Burgoyne, R.D.1    Cheek, T.R.2
  • 58
    • 0024453294 scopus 로고
    • Inositol phosphates and cell signaling
    • Berridge MJ, Irvine RF. Inositol phosphates and cell signaling. Nature 1989;341:197-205.
    • (1989) Nature , vol.341 , pp. 197-205
    • Berridge, M.J.1    Irvine, R.F.2
  • 59
    • 0009656723 scopus 로고
    • Activation mechanisms of mast cells and basophils
    • Holgate ST, Church MK, editors. London: Gower Medical Publishing
    • Kennerly D, Duffy P. Activation mechanisms of mast cells and basophils. In: Holgate ST, Church MK, editors. Allergy. London: Gower Medical Publishing; 1993. p. 4.1-4.14.
    • (1993) Allergy.
    • Kennerly, D.1    Duffy, P.2
  • 60
    • 0001180419 scopus 로고
    • The AP-1 complex and its role in transcriptional control by protein kinase C
    • Cohen P, Foulkes G, editors. Amsterdam: Elsevier/North Holland Biomedical Press
    • Karin M. The AP-1 complex and its role in transcriptional control by protein kinase C. In: Cohen P, Foulkes G, editors. Molecular aspects of cellular regulation. Vol 6. Amsterdam: Elsevier/North Holland Biomedical Press; 1990. p. 143-61.
    • (1990) Molecular Aspects of Cellular Regulation. , vol.6 , pp. 143-161
    • Karin, M.1
  • 61
    • 0024920023 scopus 로고
    • From cell code to gene code: Cytokines and transcription factors. Research review
    • Muegge K, Durum SK. From cell code to gene code: cytokines and transcription factors. Research review. The New Biologist 1989;!: 239-45.
    • (1989) The New Biologist , pp. 239-245
    • Muegge, K.1    Durum, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.