Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

Nature Immunology

Volumn 5, Issue 7, 2004, Pages 752-760

  Dillon, Stacey R ^a   Sprecher, Cindy ^a   Hammond, Angela ^a   Bilsborough, Janine ^a   Rosenfeld Franklin, Maryland ^a   Presnell, Scott R ^a   Haugen, Harald S ^a   Maurer, Mark ^a   Harder, Brandon ^a   Johnston, Janet ^a   Bort, Susan ^a   Mudri, Sherri ^a   Kuijper, Joseph L ^a   Bukowski, Tom ^a   Shea, Pamela ^a   Dong, Dennis L ^a   Dasovich, Maria ^a   Grant, Francis J ^a   Lockwood, Luann ^a   Levin, Steven D ^a   LeCiel, Cosette ^a   Waggie, Kim ^a   Day, Heather ^a   Topouzis, Stavros ^a   Kramer, Janet ^a   Kuestner, Rolf ^a   Chen, Zhi ^a   Foster, Don ^a   Parrish Novak, Julia ^a   Gross, Jane A ^a   more..

^a ZymoGenetics ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HELIX LOOP HELIX PROTEIN; INTERLEUKIN 31; INTERLEUKIN RECEPTOR; MESSENGER RNA; ONCOSTATIN M; UNCLASSIFIED DRUG; CYTOKINE RECEPTOR; GLYCOPROTEIN GP 130; IL31RA PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE;

AIRWAY; ALLERGIC DISEASE; ALOPECIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DATA ANALYSIS; DERMATITIS; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERSENSITIVITY; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRURITUS; SIGNAL TRANSDUCTION; SKIN DEFECT; T LYMPHOCYTE ACTIVATION; TH2 CELL; TRANSGENIC MOUSE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; INFUSION PUMP; LUNG; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; PATHOLOGY; POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSGENE; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; DERMATITIS; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION PROFILING; HUMANS; HYPERSENSITIVITY; INFUSION PUMPS, IMPLANTABLE; INTERLEUKINS; LUNG; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, CYTOKINE; RECEPTORS, INTERLEUKIN; RECEPTORS, ONCOSTATIN M; RNA, MESSENGER; T-LYMPHOCYTES; TRANSGENES; UP-REGULATION;

EID: 3242798310     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1084     Document Type: Article

References (37)

1. Robert, C. & Kupper, T.S. Inflammatory skin diseases, T cells, and immune surveillance. N. Engl. J. Med. 341, 1817-1828 (1999).
2. Hwang, S.T. Mechanisms of T-cell homing to skin. Adv. Dermatol. 17, 211-241 (2001).
3. Akdis, C.A. et al. T cells and T cell-derived cytokines as pathogenic factors in the nonallergic form of atopic dermatitis. J. Invest. Dermatol. 113, 628-634 (1999).
4. Leung, D.Y. & Bieber, T. Atopic dermatitis. Lancet 361, 151-160 (2003).
5. Boulay, J.L., O'Shea, J.J. & Paul, W.E. Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 19, 159-163 (2003).
6. Ghilardi, N. et al. A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT3 and STAT-5. J. Biol. Chem. 277, 16831-16836 (2002).
7. Diveu, C. et al. GPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor. J. Biol. Chem. 278, 49850-49859 (2003).
8. Lok, S. et al. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 389, 565-568 (1994).
9. Palacios, R. & Steinmetz, M. II-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41, 727-734 (1985).
10. Sprang, S.R. & Bazan, J.F. Cytokine structural taxonomy and mechanisms of receptor engagement. Curr. Opin. Struct. Biol. 3, 815-827 (1993).
11. Uzel, G., Frucht, D.M., Fleisher, T.A. & Holland, S.M. Detection of intracellular phosphorylated STAT-4 by flow cytometry. Clin. Immunol. 100, 270-276 (2001).
12. Chan, L.S., Robinson, N. & Xu, L. Expression of interleukin-4 in the epidermis of transgenic mice results in a pruritic inflammatory skin disease: an experimental animal model to study atopic dermatitis. J. Invest. Dermatol. 117, 977-983 (2001).
13. Konishi, H. et al. IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions. Proc. Natl. Acad. Sci. USA 99, 11340-11345 (2002).
14. + lymphocytes into lesional atopic dermatitis skin. J. Invest. Dermatol. 115, 640-646 (2000).
15. Tomkinson, A. et al. A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J. Immunol. 166, 5792-5800 (2001).
16. Schnare, M. et al. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2, 947-950 (2001).
17. Eisenbarth, S.C. et al. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J. Exp. Med. 196, 1645-1651 (2002).
18. Dabbagh, K., Dahl, M.E., Stepick-Biek, P. & Lewis, D.B. Toll-like receptor 4 is required for optimal development of Th2 immune responses: role of dendritic cells. J. Immunol. 168, 4524-4530 (2002).
19. Trautmann, A., Akdis, M., Brocker, E.B., Blaser, K. & Akdis, C.A. New insights into the role of T cells in atopic dermatitis and allergic contact dermatitis. Trends Immunol. 22, 530-532 (2001).
20. + T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis. J. Allergy Clin. Immunol. 107, 359-366 (2001 ).
21. Matsuda, H. et al. Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice. Int. Immunol. 9, 461-466 (1997).
22. Nickoloff, B.J. & Naidu, Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J. Am. Acad. Dermatol. 30, 535-546 (1994).
23. Matsushima, H., Hayashi, S. & Shimada, S. Skin scratching switches immune responses from Th2 to Th1 type in epicutaneously immunized mice. J. Dermatol. Sci. 32, 223-230 (2003).
24. Williams, I.R. et al. IL-7 overexpression in transgenic mouse keratinocytes causes a lymphoproliferative skin disease dominated by intermediate TCR cells: evidence for a hierarchy in IL-7 responsiveness among cutaneous T cells. J. Immunol. 159, 3044-3056 (1997).
25. Stander, S. & Steinhoff, M. Pathophysiology of pruritus in atopic dermatitis: an overview. Exp. Dermatol. 11, 12-24 (2002).
26. Nocka, K. et al. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J. 9, 1805-1813 (1990).
27. Wilkinson, J., Thomas, S., Lio, P., Holgate, S.T. & Morton, N.E. Evidence for linkage for atopy and asthma to markers on chromosome 12q. Eur. Respir. J. 9, 435s (1996).
28. Raby, B.A. et al. Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes. Hum. Mol. Genet. 12, 1973-1979 (2003).
29. Gubler, U. & Hoffman, B.J. A simple and very efficient method for generating cDNA libraries. Gene 25, 263-269 (1983).
30. + type 1 and type 2 T cells. J. Immunol. 167, 3057-3063 (2001).
31. Corti, M., Brody, A.R. & Harrison, J.H. Isolation and primary culture of murine alveolar type II cells. Am. J. Respir. Cell. Mol. Biol. 14, 309-315 (1996).
32. 1. Exp. Mol. Pathol. 71, 13-33 (2001).
33. Taboit-Dameron, F. et al. Association of the 5′HS4 sequence of the chicken β-globin locus control region with human EF1α gene promoter induces ubiquitous and high expression of human CD55 and CD59 cDNAs in transgenic rabbits. Transgenic Res. 8, 223-235 (1999).
34. Iritani, B.M., Forbush, K.A., Farrar, M.A. & Perlmutter, R.M. Control of B cell development by Ras-mediated activation of Raf. EMBO J. 16, 7019-7031 (1997).
35. Gross, J.A. et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404, 995-999 (2000).
36. Gross, J.A. et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS. Immunity 15, 289-302 (2001).
37. + effector and memory T cell generation. Nat. Immunol. 4, 835-842 (2003).